Warner Greene, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #3421
San Francisco CA 94110
Phone415-734-4805
ORCID ORCID Icon0000-0001-9896-8615 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Palo Alto, CABA1971
    Washington University School of Medicine, St. Louis, MOMD, PhD1977Medical Scientist Training Program
    Massachusetts General Hospital, Boston, MA1978Internal Medicine Internship
    Massachusetts General Hospital, Boston, MA1979Internal Medicine Residency
    Collapse Awards and Honors
    American Academy of Arts & Sciences2014Elected as Member
    Association of American Physicians2013Francis Gilman Blake Award
    Association of American Physicians2012  - 2013President
    Ohio State University Center for Retrovirus Research2012Distinguished Research Career Award
    Washington University in St. Louis2012Alumni Achievement Award
    Association of American Physicians2011  - 2012President-Elect
    Global Virus Network2011  - presCenter Director
    National Academy of Medicine2005Elected as Member
    Association of American Physicians2005  - 2011Councilor
    American Association for the Advancement of Science2004Elected Fellow
    AIDS Memorial Advisory Board2003  - presHonorary Co-Chair
    Academic Alliance Foundation2003  - presBoard of Directors
    Waterford Project2000Executive Committee and Chair of Scientific Committee
    ISI Highly Cited Researchers2001Selected as Original Member
    American Society for Clinical Investigation1998  - 2001Institutional Representative
    California Academy of Medicine1993Elected
    American Society for Clinical Investigation1993  - 1994Vice President
    Mayor's AIDS Scientific Advisory Council1997  - 1998Member
    Keystone AIDS Symposium1995Co-Chair
    1st-3rd National Conferences on Human Retroviruses & Related Infections1994  - 1996Co-Chair, Scientific Committee
    Association of American Physicians1990Elected
    Institute for Scientific Information (Science Citation Index)1981  - 1988100 Most Cited Scientists
    American Federation for Clinical Research1987Recipient, Outstanding Investigator Award
    American Society for Clinical Investigation1985Elected
    American Rheumatism Association1988Recipient, Young Investigator Award
    Washington Academy of Sciences1984Recipient, Award in the Biological Sciences
    Alpha Omega Alpha1977Elected Member
    St. Louis Internists1977Prize in Medicine
    Sigma Xi1976Research Honorary
    California Heart Association1970Recipient, Research Fellowship Award
    Stanford University1970  - 1971Honors Program in Biology
    Drexel University2015• Honorary Doctoral Degree and Commencement Speaker
    Institute of Human Virology2019Lifetime Achievement Award for Scientific Contributions

    Collapse Overview 
    Collapse Overview
    Warner C. Greene, MD, PhD is Director of the Gladstone Center for HIV Cure Research, Senior Investigator, and Nick and Sue Hellmann Distinguished Professor of Translational Medicine at the Gladstone Institute of Virology and Immunology (GIVI). He is the Founding and Emeritus Director of GIVI. Dr. Greene is also Professor of Medicine, Microbiology and of Immunology at UCSF. Dr. Greene is a member of the Institute of Medicine of the National Academies and a fellow of the American Academy for the Advancement of Science. He also serves as Co-Director of the UCSF-Gladstone Center for AIDS Research, and has served as a Councilor and President of the Association of American Physicians. Dr. Greene earned a bachelor’s degree at Stanford University and an MD/PhD at Washington University School of Medicine. He took his internship and residency training in Medicine at the Massachusetts General Hospital at Harvard. After serving as a Senior Investigator at the National Cancer Institute and a Professor of Medicine and Howard Hughes Investigator at Duke University Medical Center, Dr. Greene accepted his current position as the Founding Director of the Gladstone Institute of Virology and Immunology in 1991. The ongoing research in Dr. Greene’s laboratory focuses on the molecular mechanisms underlying HIV pathogenesis, latency, and transmission. He is the author of more than 380 scientific papers and has been recognized as one of the 100 Most Cited Scientists in the world. In 2007, Dr. Greene expanded his work to include global health in sub-Saharan Africa in his service as president and executive chairman of the Accordia Global Health Foundation. Accordia established the Infectious Diseases Institute at Makerere University in Uganda, which has trained thousands of African health care workers, is caring for 30,000 HIV-infected patients, and has brought health care to nearly 500,000 people living in remote rural regions of Uganda. In 2016, Accordia merged with Africare.
    Collapse In The News

    Collapse Research 
    Collapse Research Activities and Funding
    Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids
    NIH R01DA049525Sep 15, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Exploiting the Host-HIV Interface To Identify Biomarkers Predicting Time to Viral Rebound after Treatment Interruption
    NIH P01AI131374Aug 8, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Assessing the root causes of chronic inflammation in HIV-infected individuals using drugs of abuse
    NIH R01DA044605Jul 15, 2017 - May 31, 2022
    Role: Principal Investigator
    Durable Antibody Mediated Protection Against HIV
    NIH 1P01AI124912-01Aug 15, 2016 - Jul 31, 2020
    Role: Project Leader
    Durable Antibody Mediated Protection Against HIV
    NIH P01AI124912Aug 15, 2016 - Jul 31, 2020
    Role: Co-Investigator
    amfAR Institute for Cure Research
    amfAR, The American Foundation for AIDS Research Jan 1, 2016 - Dec 31, 2020
    Role: Project Director
    Understanding How CD4 T Cells Die During HIV Infection
    NIH R56AI118574Jul 1, 2015 - Jun 30, 2016
    Role: Principal Investigator
    HIV without AIDS: A Radically Different Approach to Help the Developing World
    NIH DP1DA036502Sep 15, 2013 - May 31, 2018
    Role: Principal Investigator
    Host Factors Influencing HIV Viral Load and Infectivity in Semen
    NIH R01HD074511Jul 25, 2012 - May 31, 2017
    Role: Co-Investigator
    HIV-Induced CD4 T-Cell Depletion: An Innate Host Defense Gone Awry?
    NIH R21AI102782Jul 1, 2012 - Jun 30, 2014
    Role: Principal Investigator
    Martin Delaney Collaboratory to Eradicate HIV-1 Infection
    NIH U19AI096113Jul 8, 2011 - Jun 30, 2016
    Role: Co-Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH P01AI083050Sep 1, 2009 - Aug 31, 2015
    Role: Principal Investigator
    Exploring and Exploiting APOBEC3G Biology
    NIH R56AI065329Sep 1, 2009 - Aug 31, 2011
    Role: Principal Investigator
    Effects of Menopause on T-cell Immunity in HIV-Infected Women
    NIH R21AI080409Sep 25, 2008 - Aug 30, 2011
    Role: Principal Investigator
    Regulation and Action of APOBEC3G
    NIH R01AI065329Jul 1, 2005 - Mar 31, 2010
    Role: Principal Investigator
    Molecular Mechanisms of HIV Post-Integration Latency
    NIH P01AI058708Sep 30, 2004 - Jan 31, 2010
    Role: Co-Investigator
    Exploring How HTLV-1 Tax Induces T Cell Leukemia
    NIH R01CA089001Jul 1, 2002 - Jun 30, 2008
    Role: Principal Investigator
    Microglia and the Neuropathogenesis of HIV Disease
    NIH R01MH064396Apr 1, 2002 - Sep 30, 2007
    Role: Principal Investigator
    GENDER EFFECTS ON HIV BIOLOGY
    NIH P01HD040543Apr 23, 2001 - Mar 31, 2008
    Role: Principal Investigator
    HIV FITNESS, VIRULENCE AND EVOLUTION
    NIH R01CA086814Jul 1, 2000 - Jun 30, 2004
    Role: Principal Investigator
    ANALYSIS OF THE ROLE OF VPR IN HIV PATHOGENESIS
    NIH R01AI045324May 15, 2000 - Apr 30, 2005
    Role: Principal Investigator
    UCSF-GVI Center for AIDS Research
    NIH 4P30AI027763-25Mar 1, 1997 - Aug 31, 2017
    Role: Co-Investigator
    Description: Dr. Greene serves as Co-Director of the UCSF–GIVI CFAR with Dr. Paul Volberding, and is Director of the CFAR Developmental Core.
    IL2 RECEPTORS--ANALYSIS OF ASSEMBLY AND SIGNALING
    NIH R01AI036452Sep 30, 1995 - Aug 31, 2001
    Role: Principal Investigator
    Signal Transduction by Cytokine Receptors in Vivo
    NIH R01GM054351Aug 1, 1995 - Mar 31, 2005
    Role: Principal Investigator
    CONFERENCE ON HIV PATHOGENESIS
    NIH R13AI037515Jan 1, 1995 - Dec 31, 1995
    Role: Principal Investigator
    PURCHASE FACS VANTAGE FLOW CYTOMETER
    NIH S10RR008263Jun 1, 1994 - May 31, 1995
    Role: Principal Investigator
    INHIBITION OF HIV-1 GROWTH TRANSCRIPTION
    NIH R01AI029117Sep 30, 1989 - Jul 31, 1994
    Role: Principal Investigator
    NEF GENE OF HIV-1
    NIH R01AI028240Apr 1, 1989 - Mar 31, 2001
    Role: Principal Investigator
    UCSF-Gladstone Center for AIDS Research
    NIH P30AI027763Sep 30, 1988 - Aug 31, 2022
    Role: Co-Investigator
    General Clinical Research Center
    NIH M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Rep. 2023 Sep 26; 42(9):113055. Li Z, Deeks SG, Ott M, Greene WC. PMID: 37682714; PMCID: PMC10591912.
      View in: PubMed   Mentions:    Fields:    
    2. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 12 20; 13(6):e0230822. Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. PMID: 36314791; PMCID: PMC9765283.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    3. SARS-CoV-2 can infect human embryos. Sci Rep. 2022 09 14; 12(1):15451. Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, Zouves CG, Greene WC, Viotti M. PMID: 36104397; PMCID: PMC9472724.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    4. CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio. 2022 10 26; 13(5):e0189122. Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. PMID: 36073812; PMCID: PMC9600577.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    5. Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV. Viruses. 2022 08 04; 14(8). George AF, McGregor M, Gingrich D, Neidleman J, Marquez RS, Young KC, Thanigaivelan KL, Greene WC, Tien PC, Deitchman AN, Spitzer TL, Roan NR. PMID: 36016345; PMCID: PMC9413545.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training. Afr Health Sci. 2022 Aug; 22(Spec Issue):1-10. Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-Mbidde E, Musoke P, Joloba M, McKinnell H, Kamya M, Mayanja-Kizza H, Manabe YC, Kambugu A. PMID: 36321127; PMCID: PMC9590334.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. Nat Commun. 2022 07 30; 13(1):4422. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 35908075; PMCID: PMC9338928.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    8. Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. JCI Insight. 2022 06 22; 7(12). Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens J, Rincon M, Myatt L, Asiodu IV, Flaherman VJ, Afshar Y, Jacoby VL, Murtha AP, Robinson JF, Ott M, Greene WC, Gaw SL. PMID: 35579965; PMCID: PMC9309042.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    9. Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq. Front Immunol. 2022; 13:883420. Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC. PMID: 35784348; PMCID: PMC9245423.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    10. Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. Nature. 2022 07; 607(7918):351-355. Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. PMID: 35584773; PMCID: PMC9279157.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination. medRxiv. 2022 Feb 09. Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna J, Ott M. PMID: 35075459; PMCID: PMC8786226.
      View in: PubMed   Mentions:
    12. Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. Front Immunol. 2022; 13:803417. George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. PMID: 35154118; PMCID: PMC8829545.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. Res Sq. 2021 Dec 15. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931183; PMCID: PMC8687466.
      View in: PubMed   Mentions:
    14. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. medRxiv. 2021 Dec 13. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. PMID: 34931197; PMCID: PMC8687468.
      View in: PubMed   Mentions: 2  
    15. Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status. Front Microbiol. 2021; 12:763030. Pedersen JG, Egedal JH, Packard TA, Thavachelvam K, Xie G, van der Sluis RM, Greene WC, Roan NR, Jakobsen MR. PMID: 34899645; PMCID: PMC8661899.
      View in: PubMed   Mentions:
    16. SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. bioRxiv. 2021 Oct 13. Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K. PMID: 34671772; PMCID: PMC8528086.
      View in: PubMed   Mentions: 1  
    17. mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status. Elife. 2021 10 12; 10. Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. PMID: 34636722; PMCID: PMC8545397.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCellsPHPublic Health
    18. Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission. J Biol Chem. 2021 10; 297(4):101098. Luo X, Mouquet H, Schwartz O, Greene WC. PMID: 34418431; PMCID: PMC8446805.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status. bioRxiv. 2021 Jul 29. Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. PMID: 34013277; PMCID: PMC8132283.
      View in: PubMed   Mentions: 1  
    20. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. Cell Rep. 2021 07 20; 36(3):109414. Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR. PMID: 34260965; PMCID: PMC8238659.
      View in: PubMed   Mentions: 49     Fields:    
    21. Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection. Mucosal Immunol. 2021 09; 14(5):1203-1213. Egedal JH, Xie G, Packard TA, Laustsen A, Neidleman J, Georgiou K, Pillai SK, Greene WC, Jakobsen MR, Roan NR. PMID: 33976386; PMCID: PMC8379073.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    22. Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell Rep. 2021 04 27; 35(4):109038. Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. PMID: 33910003; PMCID: PMC8202093.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    23. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. medRxiv. 2021 Feb 05. Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. PMID: 33532792; PMCID: PMC7852243.
      View in: PubMed   Mentions: 1  
    24. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. J Virol. 2021 03 25; 95(8). Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. PMID: 33536176; PMCID: PMC8103695.
      View in: PubMed   Mentions: 8     Fields:    
    25. Identification of unrecognized host factors promoting HIV-1 latency. PLoS Pathog. 2020 12; 16(12):e1009055. Li Z, Hajian C, Greene WC. PMID: 33270809; PMCID: PMC7714144.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    26. Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. PLoS Pathog. 2020 11; 16(11):e1009060. Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. PMID: 33253324; PMCID: PMC7728277.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    27. Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. Elife. 2020 09 29; 9. Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. PMID: 32990219; PMCID: PMC7524554.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    28. SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential. Cell Rep Med. 2020 09 22; 1(6):100081. Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. PMID: 32839763; PMCID: PMC7437502.
      View in: PubMed   Mentions: 120     Fields:    
    29. SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential. bioRxiv. 2020 Aug 03. Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. PMID: 32577663; PMCID: PMC7302219.
      View in: PubMed   Mentions: 1  
    30. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020 05 26; 9. Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. PMID: 32452381; PMCID: PMC7250576.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    31. Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450. Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080; PMCID: PMC7192375.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    32. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 03 27; 35(3):617-640. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408; PMCID: PMC7105328.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    33. Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy. Viruses. 2020 02 08; 12(2). Schwarzer R, Gramatica A, Greene WC. PMID: 32046251; PMCID: PMC7077203.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    34. HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1. J Virol. 2019 12 15; 93(24). Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC. PMID: 31578293; PMCID: PMC6880156.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    35. Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology. 2019 11 11; 16(1):32. Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. PMID: 31711503; PMCID: PMC6849327.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    36. Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 10 31; 179(4):880-894.e10. Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804; PMCID: PMC6922308.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
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    38. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 11; 111:373-381. Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. PMID: 30300855; PMCID: PMC6364691.
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    39. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 08 01; 99(2):336-348. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. PMID: 29518187; PMCID: PMC6084595.
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    40. Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7. Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165; PMCID: PMC5973828.
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    41. Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Cell Rep. 2017 07 25; 20(4):984-998. Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. PMID: 28746881; PMCID: PMC5560086.
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    43. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 2017 May 10; 21(5):569-579.e6. Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238; PMCID: PMC5490666.
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    48. Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. J Biol Chem. 2016 Jul 01; 291(27):14045-14055. LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI. PMID: 27226574; PMCID: PMC4933164.
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    49. Dissecting How CD4 T Cells Are Lost During HIV Infection. Cell Host Microbe. 2016 Mar 09; 19(3):280-91. Doitsh G, Greene WC. PMID: 26962940; PMCID: PMC4835240.
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    50. Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Cell Host Microbe. 2015 Oct 14; 18(4):463-70. Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. PMID: 26468749; PMCID: PMC4627664.
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    53. Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med. 2014 Nov 12; 6(262):262ra157. Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J. PMID: 25391483; PMCID: PMC4372245.
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    54. HIV-1 Fusion Assay. Bio Protoc. 2014 Aug 20; 4(16). Cavrois M, Neidleman J, Greene WC. PMID: 27525294; PMCID: PMC4982656.
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    56. Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol. 2014 Jul; 88(13):7221-34. Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. PMID: 24741080; PMCID: PMC4054457.
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    57. Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. J Infect Dis. 2014 Oct 01; 210(7):1062-6. Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC. PMID: 24719472; PMCID: PMC4168303.
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    58. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun. 2014 Apr 01; 5:3508. Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. PMID: 24691351; PMCID: PMC4129123.
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    60. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature. 2014 Jan 23; 505(7484):509-14. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. PMID: 24356306; PMCID: PMC4047036.
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    61. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. PLoS Pathog. 2013; 9(12):e1003834. Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. PMID: 24385908; PMCID: PMC3873446.
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    62. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science. 2014 Jan 24; 343(6169):428-32. Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. PMID: 24356113; PMCID: PMC3976200.
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    64. Solutions to global health challenges: no more Band-Aids. J Clin Invest. 2013 Nov; 123(11):4967-70. Greene WC. PMID: 24177468; PMCID: PMC3809817.
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    65. Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV. PLoS One. 2013; 8(10):e77749. Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC. PMID: 24204950; PMCID: PMC3813743.
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    66. An integrated overview of HIV-1 latency. Cell. 2013 Oct 24; 155(3):519-29. Ruelas DS, Greene WC. PMID: 24243012; PMCID: PMC4361081.
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    67. Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. J Virol. 2013 Dec; 87(24):13354-69. Webster B, Ott M, Greene WC. PMID: 24089557; PMCID: PMC3838274.
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    68. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013; 9(4):e1003302. Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. PMID: 23593007; PMCID: PMC3623766.
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    71. Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis. Immunol Rev. 2012 Mar; 246(1):286-310. Chan JK, Greene WC. PMID: 22435562.
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    72. Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3035-40. Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK, Swiss HIV Cohort Study. PMID: 22315404; PMCID: PMC3286922.
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    74. Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. J Virol. 2012 Mar; 86(5):2556-70. Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. PMID: 22205732; PMCID: PMC3302289.
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    75. Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe. 2011 Dec 15; 10(6):541-50. Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC. PMID: 22177559; PMCID: PMC3257029.
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    76. Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol. 2012 Jan; 86(2):1244-9. Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J. PMID: 22090109; PMCID: PMC3255800.
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    78. Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. PLoS Pathog. 2011 Oct; 7(10):e1002284. Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML. PMID: 21998583; PMCID: PMC3188525.
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    79. HIV latency. Cold Spring Harb Perspect Med. 2011 Sep; 1(1):a007096. Siliciano RF, Greene WC. PMID: 22229121; PMCID: PMC3234450.
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    81. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog. 2011 Aug; 7(8):e1002184. Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. PMID: 21876670; PMCID: PMC3158049.
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    82. NF-κB/Rel: agonist and antagonist roles in HIV-1 latency. Curr Opin HIV AIDS. 2011 Jan; 6(1):12-8. Chan JK, Greene WC. PMID: 21242888; PMCID: PMC3493179.
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    91. Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). J Biol Chem. 2010 Jan 15; 285(3):1861-9. Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC. PMID: 19897482; PMCID: PMC2804344.
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    94. Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Retrovirology. 2009 Jan 13; 6:2. Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT. PMID: 19144136; PMCID: PMC2631513.
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    98. Novel targets for HIV therapy. Antiviral Res. 2008 Dec; 80(3):251-65. Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T. PMID: 18789977.
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    108. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J Immunol. 2007 May 15; 178(10):6581-9. Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM. PMID: 17475889.
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    110. APOBEC3G and HIV-1: strike and counterstrike. Curr HIV/AIDS Rep. 2007 Feb; 4(1):3-9. Soros VB, Greene WC. PMID: 17338854.
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    112. In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog. 2007 Jan; 3(1):e4. Cavrois M, Neidleman J, Kreisberg JF, Greene WC. PMID: 17238285; PMCID: PMC1779297.
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    114. A plea for justice for jailed medical workers. Science. 2006 Nov 10; 314(5801):924-5. Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. PMID: 17062652.
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    116. NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Mol Cell Biol. 2006 Oct; 26(19):7283-98. O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC. PMID: 16980629; PMCID: PMC1592877.
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    117. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol. 2006 Nov; 80(21):10407-18. Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. PMID: 16956949; PMCID: PMC1641771.
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    120. Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. J Exp Med. 2006 Apr 17; 203(4):865-70. Kreisberg JF, Yonemoto W, Greene WC. PMID: 16606671; PMCID: PMC2118295.
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    121. Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin. J Biol Chem. 2006 Jun 02; 281(22):15099-109. Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ. PMID: 16554298.
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    122. Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol. 2006 Feb; 80(4):1992-9. Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC. PMID: 16439555; PMCID: PMC1367165.
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    124. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 2006 Jan 11; 25(1):139-49. Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. PMID: 16319923; PMCID: PMC1356344.
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    126. NF-kappaB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol. 2005 Sep; 25(18):7966-75. Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC. PMID: 16135789; PMCID: PMC1234328.
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    127. Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. J Biol Chem. 2005 Oct 21; 280(42):35713-22. Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC. PMID: 16105841.
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    129. Host factors regulating post-integration latency of HIV. Trends Microbiol. 2005 Apr; 13(4):137-9. Williams SA, Greene WC. PMID: 15817380.
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    130. Protecting APOBEC3G: a potential new target for HIV drug discovery. Curr Opin Investig Drugs. 2005 Feb; 6(2):141-7. Stopak K, Greene WC. PMID: 15751736.
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    131. Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef. J Virol. 2005 Feb; 79(3):1655-65. Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT. PMID: 15650191; PMCID: PMC544094.
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    132. Studies of ebola virus glycoprotein-mediated entry and fusion by using pseudotyped human immunodeficiency virus type 1 virions: involvement of cytoskeletal proteins and enhancement by tumor necrosis factor alpha. J Virol. 2005 Jan; 79(2):918-26. Yonezawa A, Cavrois M, Greene WC. PMID: 15613320; PMCID: PMC538559.
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    134. The brightening future of HIV therapeutics. Nat Immunol. 2004 Sep; 5(9):867-71. Greene WC. PMID: 15334078.
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    135. Redistricting the retroviral restriction factors. Nat Med. 2004 Aug; 10(8):778-80. Greene WC. PMID: 15286773.
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    136. Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem. 2004 Oct 01; 279(40):42008-17. Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. PMID: 15284245.
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    137. Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol. 2004 May; 5(5):392-401. Chen LF, Greene WC. PMID: 15122352.
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    138. p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem. 2004 Jun 18; 279(25):26115-25. Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC. PMID: 15073170.
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    139. Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. J Biol Chem. 2004 Apr 30; 279(18):18137-45. O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC. PMID: 14963024.
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    140. Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J Virol. 2004 Feb; 78(3):1375-83. Schaeffer E, Soros VB, Greene WC. PMID: 14722292; PMCID: PMC321368.
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    141. Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Methods Mol Biol. 2004; 263:333-44. Cavrois M, Neidleman J, Bigos M, Greene WC. PMID: 14976375.
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    142. Regulation of NF-kappaB action by reversible acetylation. Novartis Found Symp. 2004; 259:208-17; discussion 218-25. Greene WC, Chen LF. PMID: 15171256.
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    143. How resting T cells deMURR HIV infection. Nat Immunol. 2004 Jan; 5(1):18-9. Greene WC. PMID: 14699403.
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    144. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol Cell. 2003 Sep; 12(3):591-601. Stopak K, de Noronha C, Yonemoto W, Greene WC. PMID: 14527406.
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    145. Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J Mol Med (Berl). 2003 Sep; 81(9):549-57. Chen LF, Greene WC. PMID: 12920522.
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    146. Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem. 2003 Oct 31; 278(44):43202-13. Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. PMID: 12881522.
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    147. Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. J Virol. 2003 Jul; 77(13):7582-9. Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC. PMID: 12805458; PMCID: PMC164827.
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    148. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J Virol. 2003 Feb; 77(3):2124-33. Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC. PMID: 12525647; PMCID: PMC140869.
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    149. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med. 2002 Jul; 8(7):673-80. Greene WC, Peterlin BM. PMID: 12091904.
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    150. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J Exp Med. 2001 Nov 19; 194(10):1407-19. Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA. PMID: 11714748; PMCID: PMC2193684.
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    151. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science. 2001 Nov 02; 294(5544):1105-8. de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC. PMID: 11691994.
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    152. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001 Aug 31; 293(5535):1653-7. Fischle W, Verdin E, Greene WC. PMID: 11533489.
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    153. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature. 2001 Apr 12; 410(6830):834-8. Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. PMID: 11298454.
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    154. Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J Virol. 2001 Mar; 75(6):2993-3000. Schaeffer E, Geleziunas R, Greene WC. PMID: 11222724; PMCID: PMC115925.
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    156. The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. J Biol Chem. 2000 Nov 03; 275(44):34021-4. Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. PMID: 10980190.
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    157. NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J Neurosci. 2000 Oct 15; 20(20):7556-63. Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. PMID: 11027214; PMCID: PMC6772878.
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    159. Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO J. 2000 Sep 01; 19(17):4712-22. Lin L, DeMartino GN, Greene WC. PMID: 10970863; PMCID: PMC302078.
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    161. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Mol Cell Biol. 2000 Apr; 20(8):2933-40. Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. PMID: 10733597; PMCID: PMC85537.
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    162. Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Mol Cell Biol. 2000 Feb; 20(4):1170-8. O'Mahony A, Lin X, Geleziunas R, Greene WC. PMID: 10648602; PMCID: PMC85235.
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    163. The generation of nfkb2 p52: mechanism and efficiency. Oncogene. 1999 Nov 04; 18(46):6201-8. Heusch M, Lin L, Geleziunas R, Greene WC. PMID: 10597218.
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    164. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J Immunol. 1999 Sep 15; 163(6):2977-81. Bresnahan PA, Yonemoto W, Greene WC. PMID: 10477559.
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    165. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases. Immunity. 1999 Feb; 10(2):271-80. Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC. PMID: 10072079.
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    169. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol. 1998 Sep; 18(9):5157-65. Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. PMID: 9710600; PMCID: PMC109101.
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    174. Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity. Virology. 1997 Aug 04; 234(2):215-25. Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC. PMID: 9268152.
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    179. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem. 1996 Aug 30; 271(35):21381-90. Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. PMID: 8702919.
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    181. Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Aug 01; 12(4):343-51. Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. PMID: 8673542.
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    183. Is the Nef protein of HIV-1 required for pathogenesis? Trends Microbiol. 1996 May; 4(5):171-2; discussion 173. Miller MD, Greene WC. PMID: 8727595.
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    184. Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Am J Pathol. 1996 May; 148(5):1661-70. Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. PMID: 8623933; PMCID: PMC1861566.
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    185. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Mol Cell Biol. 1996 Mar; 16(3):1058-65. Sun S, Elwood J, Greene WC. PMID: 8622650; PMCID: PMC231088.
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    186. The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Proc Natl Acad Sci U S A. 1996 Jan 09; 93(1):231-5. Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. PMID: 8552611; PMCID: PMC40212.
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    187. Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction. J Acquir Immune Defic Syndr Hum Retrovirol. 1996; 13 Suppl 1:S76-84. Béraud C, Greene WC. PMID: 8797708.
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    188. Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. J Biol Chem. 1995 Dec 01; 270(48):28858-63. Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC, et al. PMID: 7499411.
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    189. Predicting progression to AIDS. Ann Intern Med. 1995 Nov 01; 123(9):726-7. Greene WC. PMID: 7574230.
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    191. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. J Biol Chem. 1995 Sep 15; 270(37):21729-37. Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. PMID: 7665592.
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    192. Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc Natl Acad Sci U S A. 1995 Aug 01; 92(16):7192-6. Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. PMID: 7543676; PMCID: PMC41305.
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    194. Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain. J Immunol. 1995 Mar 01; 154(5):2033-40. Goldsmith MA, Amaral MC, Greene WC. PMID: 7868880.
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    195. Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. J Virol. 1995 Jan; 69(1):579-84. Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC. PMID: 7983759; PMCID: PMC188614.
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    198. The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. J Biol Chem. 1994 May 20; 269(20):14698-704. Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC. PMID: 8182077.
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    199. The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. Leukemia. 1994 Apr; 8 Suppl 1:S186-9. Williamson P, Merida I, Greene WC, Gaulton G. PMID: 8152289.
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    200. Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1346-50. Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC. PMID: 8108414; PMCID: PMC43155.
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    201. Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency. Mol Cell Biol. 1994 Feb; 14(2):1374-82. Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC. PMID: 8289813; PMCID: PMC358492.
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    204. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 1993 Oct; 12(10):3879-91. Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. PMID: 8404856; PMCID: PMC413671.
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    209. The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation. J Biol Chem. 1993 Mar 25; 268(9):6765-70. Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN. PMID: 8384218.
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    210. Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function. Virology. 1993 Mar; 193(1):41-9. Hammes SR, Greene WC. PMID: 8438577.
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    217. Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. J Virol. 1992 Jul; 66(7):4540-5. Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E. PMID: 1602559; PMCID: PMC241265.
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    218. Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. J Clin Invest. 1992 Jul; 90(1):121-9. Kaufman PA, Weinberg JB, Greene WC. PMID: 1634604; PMCID: PMC443070.
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    219. Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein. Virology. 1992 Mar; 187(1):316-20. Smith MR, Greene WC. PMID: 1736534.
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    220. The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1875-9. Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC. PMID: 1542686; PMCID: PMC48556.
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    259. Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7709-13. Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G. PMID: 3051003; PMCID: PMC282262.
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    260. HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science. 1988 Sep 23; 241(4873):1652-5. Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC. PMID: 2843985.
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    261. p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei. J Immunol. 1988 Aug 15; 141(4):1358-64. Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S. PMID: 3135330.
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    262. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell. 1988 Jun 03; 53(5):827-36. Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC. PMID: 2836068.
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    263. Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4468-72. Lowenthal JW, Böhnlein E, Ballard DW, Greene WC. PMID: 3132714; PMCID: PMC280451.
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    264. Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. J Biol Chem. 1988 Apr 05; 263(10):4900-6. Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC. PMID: 2832410.
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    265. Sarcoidosis and interleukin-2 receptors. Am Rev Respir Dis. 1988 Apr; 137(4):757-8. Greene WC. PMID: 2833139.
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    266. Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation. Gastroenterology. 1988 Mar; 94(3):647-55. Zeitz M, Greene WC, Peffer NJ, James SP. PMID: 3123303.
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    267. The human interleukin-2 receptor. Recent studies of structure and regulation. Ann N Y Acad Sci. 1988; 546:116-21. Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J. PMID: 3073691.
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    268. In: Smith KA (Ed.), Interleukin 2. New perspectives on the structure of the human high affinity i nterleukin-2 receptor. 1988; 99-112. Wano Y, Dukovich M, Kehrl JH, Greene WC.
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    270. Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. J Clin Invest. 1988 Jan; 81(1):200-5. Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC. PMID: 2826541; PMCID: PMC442494.
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    271. In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic principles and clinical correlations. IL-2, IL-2 receptors, and the growth of human T cells. 1988; 209-288. Greene WC.
    272. Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Science. 1987 Dec 11; 238(4833):1575-8. Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. PMID: 2825351.
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    273. Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. J Immunol. 1987 Oct 01; 139(7):2355-60. Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G. PMID: 2821112.
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    274. Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor. J Exp Med. 1987 Oct 01; 166(4):1156-61. Lowenthal JW, Greene WC. PMID: 3116145; PMCID: PMC2188735.
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    275. Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. J Immunol. 1987 Sep 01; 139(5):1550-6. Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC. PMID: 3040856.
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    276. Interleukin 1 gene expression in adult T cell leukemia. J Clin Invest. 1987 Sep; 80(3):911-6. Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC. PMID: 2887587; PMCID: PMC442321.
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    277. The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function. Clin Res. 1987 Sep; 35(5):439-50. Greene WC. PMID: 2889557.
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    278. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5389-93. Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. PMID: 3037548; PMCID: PMC298861.
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    279. A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Nature. 1987 Jun 11-17; 327(6122):518-22. Dukovich M, Wano Y, Katz P, Cullen BR, Kehrl JH, Greene WC. PMID: 3108674.
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    280. Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. J Immunol. 1987 May 01; 138(9):2917-22. Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA. PMID: 3106493.
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    281. Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors. Proc Natl Acad Sci U S A. 1987 Apr; 84(7):2002-6. Robb RJ, Rusk CM, Yodoi J, Greene WC. PMID: 3031660; PMCID: PMC304571.
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    282. Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor. J Exp Med. 1987 Apr 01; 165(4):1201-6. Robb RJ, Greene WC. PMID: 3031195; PMCID: PMC2188578.
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    283. High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule. Proc Natl Acad Sci U S A. 1987 Apr; 84(8):2125-9. Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J. PMID: 3104909; PMCID: PMC304601.
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    284. Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. Mol Biol Med. 1987 Apr; 4(2):95-109. Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC. PMID: 3114593.
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    285. Trans-activator gene of HTLV-II: interpretation. Science. 1987 Feb 27; 235(4792):1073. Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. PMID: 3029865.
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    286. An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties. Cancer Invest. 1987; 5(4):369-76. Greene WC. PMID: 2889515.
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    287. Human interleukin 2 receptor (Tac antigen). Methods Enzymol. 1987; 150:682-700. Greene WC, Leonard WJ. PMID: 3123879.
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    293. Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Mol Cell Biol. 1986 Dec; 6(12):4244-50. Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC. PMID: 2432398; PMCID: PMC367205.
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    294. Characterization of the human interleukin 2 receptor at the DNA, RNA, and protein level. Immunobiology. 1986 Sep; 172(3-5):357-64. Greene WC. PMID: 3100432.
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    295. The human interleukin-2 receptor: analysis of structure and function. Immunol Rev. 1986 Aug; 92:29-48. Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 3091481.
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    296. Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin. Cancer Res. 1986 Jul; 46(7):3295-8. Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC. PMID: 3011246.
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    297. A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA. J Immunol. 1986 Jun 01; 136(11):4099-105. Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC. PMID: 3084654.
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    298. Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Science. 1986 May 16; 232(4752):877-80. Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. PMID: 3010456.
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    299. Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Proc Natl Acad Sci U S A. 1986 Mar; 83(5):1463-6. Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD. PMID: 3081898; PMCID: PMC323096.
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    301. The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 2:731-7. Greene WC, Depper JM, Krönke M, Leonard WJ. PMID: 2884072.
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    302. Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor. Prog Hematol. 1986; 14:283-301. Greene WC, Leonard WJ, Depper JM. PMID: 2418464.
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    303. In: Marget M, Lang W, Gabler-Sandberger E (Eds.), Proceedings of the IXth International Congress of Infectious and Parasitic Diseases. The transactivator (tat) gene of HTLV-II activates IL-2 receptor, IL-2, and class II major histocompatibility complex cellular gene expression. 1986; 1:67-69. Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA.
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    306. In: Pincus S, Pisetsky D, Rosenwasser L (Eds.), Biologically based immunomodulators in the therapy of rheumatic diseases. The human receptor for interleukin-2: characterization, controversies, and expression in rheumatic diseases. 1986; 297-306. Depper JM, Leonard WJ, Greene WC.
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    308. Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level. J Immunol. 1985 Oct; 135(4):2478-82. Reed JC, Greene WC, Hoover RG, Nowell PC. PMID: 3928749.
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    309. Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor. Cancer Res. 1985 Sep; 45(9 Suppl):4563s-4567s. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA, et al. PMID: 2990688.
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    310. Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia. Cancer Res. 1985 Sep; 45(9 Suppl):4559s-4562s. Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC. PMID: 2990687.
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    311. Interleukin 2 receptor gene expression in normal human T lymphocytes. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6281-5. Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC. PMID: 3929255; PMCID: PMC391037.
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    312. Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med. 1985 Jul 11; 313(2):79-84. Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS. PMID: 2582258.
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    313. Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells. J Exp Med. 1985 Jul 01; 162(1):363-8. Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ. PMID: 2989411; PMCID: PMC2187706.
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    314. Localization of the gene encoding the human interleukin-2 receptor on chromosome 10. Science. 1985 Jun 28; 228(4707):1547-9. Leonard WJ, Donlon TA, Lebo RV, Greene WC. PMID: 3925551.
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    315. Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia. Science. 1985 Jun 07; 228(4704):1215-7. Krönke M, Leonard WJ, Depper JM, Greene WC. PMID: 2988127.
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    316. Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4230-4. Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. PMID: 2987968; PMCID: PMC397970.
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    317. Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol. 1985 Jun; 134(6):4212-7. Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN. PMID: 3921620.
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    318. Adult T cell leukemia: a potential target for ricin A chain immunotoxins. Blood. 1985 Jun; 65(6):1416-21. Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC. PMID: 2986744.
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    319. Sequential expression of genes involved in human T lymphocyte growth and differentiation. J Exp Med. 1985 Jun 01; 161(6):1593-8. Krönke M, Leonard WJ, Depper JM, Greene WC. PMID: 2989408; PMCID: PMC2187631.
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    329. Molecular cloning of cDNA for the human interleukin-2 receptor. Haematol Blood Transfus. 1985; 29:388-95. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA, et al. PMID: 2993133.
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    331. In: Cancer Cells 3: Growth factors and transformation. Structure, function, and expression of the receptor for interleukin-2 on normal and malignant lymphocytes. 1985; 221-226. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC.
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    339. Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen. J Exp Med. 1984 Oct 01; 160(4):1126-46. Robb RJ, Greene WC, Rusk CM. PMID: 6090574; PMCID: PMC2187485.
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    341. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A. 1984 Aug; 81(16):5214-8. Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. PMID: 6332315; PMCID: PMC391668.
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    342. Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor. J Clin Invest. 1984 Jun; 73(6):1711-8. Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM, et al. PMID: 6327770; PMCID: PMC437083.
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    343. Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate. J Immunol. 1984 Jan; 132(1):31-7. Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH. PMID: 6418801.
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    344. Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia. Princess Takamatsu Symp. 1984; 15:259-68. Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC. PMID: 6100644.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    345. Interleukin-2 receptors on activated malignant and normal B-cells. Curr Top Microbiol Immunol. 1984; 113:96-101. Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC. PMID: 6236954.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    346. In: Pick E (Ed.), Lymphokines. A monoclonal antibody which recognizes the human receptor for T cell growth factor: Functional effects and use as a probe to investigate receptor regulation. 1984; 9:127-152. Depper JM, Leonard WJ, Waldmann TA, Greene WC.
    347. In: Sasazuki T (Ed.), Immunogenetics: Its application to clinical medicine. Cell-cell interactions in the human immune response: Analysis of leukemic T calls with immunoregulatory functions. 1984; 137-142. Waldmann TA, Broder S, Greene WC.
    348. In: Greaves M (Ed.), Receptors and Recognition. A monoclonal antibody to the human receptor for T cell growth factor. 1984; 17:45-66. Leonard WJ, Depper JM, Waldmann TA, Greene WC.
    349. Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques. J Clin Invest. 1983 Dec; 72(6):1987-94. Littman BH, Muchmore AV, Steinberg AD, Greene WC. PMID: 6605979; PMCID: PMC437039.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    350. Characterization of the human receptor for T-cell growth factor. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6957-61. Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC. PMID: 6417659; PMCID: PMC390105.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    351. Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Nature. 1983 Oct 20-26; 305(5936):733-6. Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S. PMID: 6195529.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    352. Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen. J Exp Med. 1983 Oct 01; 158(4):1332-7. Robb RJ, Greene WC. PMID: 6413637; PMCID: PMC2187370.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    353. Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol. 1983 Aug; 131(2):690-6. Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC. PMID: 6408186.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    354. Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A. 1983 Jul; 80(14):4522-6. Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA. PMID: 6192435; PMCID: PMC384071.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    355. Evidence for an interleukin-independent pathway for human lymphocyte activation. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3444-7. Koretzky GA, Daniele RP, Greene WC, Nowell PC. PMID: 6407014; PMCID: PMC394060.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    356. Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen. J Exp Med. 1983 Mar 01; 157(3):1064-9. Cossman J, Neckers LM, Leonard WJ, Greene WC. PMID: 6220104; PMCID: PMC2186955.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    357. The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation. Am J Pediatr Hematol Oncol. 1983; 5(2):199-206. Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV. PMID: 6193722.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    358. In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology. Hairy cell leukemia: A malignant expansion of B cells that express Tac antigen. 1983; 9:491-500. Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ.
    359. Construction of human suppressor T cell hybridomas. Lymphokine Res. 1983; 2(2):53-60. Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA. PMID: 6236341.
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    360. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature. 1982 Nov 18; 300(5889):267-9. Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. PMID: 6815536.
      View in: PubMed   Mentions: 215     Fields:    Translation:Humans
    361. Production of human suppressor T cell hybridomas. J Immunol. 1982 Nov; 129(5):1986-92. Greene WC, Fleisher TA, Nelson DL, Waldmann TA. PMID: 6214585.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    362. Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis. J Immunol. 1982 Sep; 129(3):1099-103. Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC. PMID: 6179992.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    363. Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells. J Immunol. 1982 Sep; 129(3):1120-3. Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA. PMID: 6213708.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    364. In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines. Monoclonal anti-Tac blocks the action of human interleukin-2. 1982; 19-24. Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC.
    365. Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes. J Immunol. 1981 Aug; 127(2):799-804. Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA. PMID: 6265558.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    366. Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line. J Exp Med. 1981 Jul 01; 154(1):156-67. Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA. PMID: 6454754; PMCID: PMC2186401.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    367. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation. J Immunol. 1981 Mar; 126(3):1185-91. Greene WC, Fleisher TA, Waldmann TA. PMID: 6450803.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    368. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production. J Immunol. 1981 Mar; 126(3):1192-7. Fleisher TA, Greene WC, Blaese RM, Waldmann TA. PMID: 6450804.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    369. Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes. J Immunol. 1981 Feb; 126(2):580-6. Greene WC, Fleisher TA, Waldmann TA. PMID: 6778919.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    370. Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin. J Immunol. 1980 Jun; 124(6):2979-87. Greene WC, Waldmann TA. PMID: 6966300.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    371. In: Cramer H, Schultz J (Eds.), Mechanism of Action. Cyclic nucleotides in the immune response. 1977; 161-187. Parker CW, Greene WC.
    372. Cytochalasin sensitive structures and lymphocyte activation. Exp Cell Res. 1976 Nov; 103(1):109-17. Greene WC, Parker CM, Parker CW. PMID: 186286.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    373. Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes. Exp Cell Res. 1976 Nov; 103(1):99-108. Parker CW, Greene WC, MacDonald HH. PMID: 991953.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    374. Colchicine-sensitive structures and lymphocyte activation. J Immunol. 1976 Sep; 117(3):1015-22. Greene WC, Parker CM, Parker CW. PMID: 956646.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    375. Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal. J Biol Chem. 1976 Jul 10; 251(13):4017-25. Greene WC, Parker CM, Parker CW. PMID: 932019.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    376. Calcium and lymphocyte activation. Cell Immunol. 1976 Jul; 25(1):74-89. Greene WC, Parker CM, Parker CW. PMID: 183895.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    377. Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers. Exp Cell Res. 1976 May; 99(2):395-407. Atkinson JP, Greene WC, McNearney TA, Parker CW. PMID: 178514.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    378. Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins. Immunol Commun. 1976; 5(1-2):13-25. Parker CW, Dankner RE, Falkenhein SF, Greene WC. PMID: 181319.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    379. In: Eijsvoogel W, Roos D, Zeijlemaker WP (Eds.), Leukocyte membrane determinants regulating immune reactivity. Calcium ionophore A23187 and lymphocyte activation. 1976; 10:129. Greene WC, Wedner HJ, Parker CW.
    380. A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes. Biochem Biophys Res Commun. 1975 Jul 22; 65(2):456-63. Greene WC, Parker CW. PMID: 167774.
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    381. Concanavalin A-induced histamine release from normal rat mast cells. J Immunol. 1975 Jul; 115(1):278-82. Sullivan TJ, Greene WC, Parker CW. PMID: 50352.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    382. Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis. Diabetes. 1971 Oct; 20(10):649-54. Peterson DT, Greene WC, Reaven GM. PMID: 5110696.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
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