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Alessandro Didonna, PhD

TitleAdjunct Instructor
SchoolUCSF School of Medicine
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-476-1335
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    Collapse Biography 
    Collapse Education and Training
    University of Bari, ItalyB.Sc.2004Cell and Molecular Biology
    University of Bari, ItalyM.Sc.2006Cell and Molecular Biology
    International School for Advanced Studies, ItalyPh.D.2010Functional and Structural Genomics
    Northwestern UniversityPostdoctoral Fellow2011Neurology
    University of California, San FranciscoPostdoctoral Fellow2013Neurology
    Collapse Awards and Honors
    Italian Multiple Sclerosis Foundation (FISM)2015  - 2017Senior Research Fellowship
    American Neurological Association2015Travel Grant
    American Society for Cell Biology2016Travel Grant
    Italian Multiple Sclerosis Foundation (FISM)2017Young Researcher Best Poster Award
    Conrad N. Hilton Foundation2017  - 2019Marilyn Hilton Award for Innovation in MS Research
    American Society for Cell Biology2017Travel Grant

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Didonna A, Oksenberg JR. Multiple Sclerosis: Perspectives in Treatment and Pathogenesis. Ian S. Zagon and Patricia J. McLaughlin (Editors). The Genetics of Multiple Sclerosis. 2017; 3-16.
    2. Guglielmetti C, Najac C, Didonna A, Van der Linden A, Ronen SM, Chaumeil MM. Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model. Proc Natl Acad Sci U S A. 2017 Aug 15; 114(33):E6982-E6991. PMID: 28760957.
      View in: PubMed
    3. Didonna A, Opal P. Advances in Sequencing Technologies for Understanding Hereditary Ataxias: A Review. JAMA Neurol. 2016 Dec 01; 73(12):1485-1490. PMID: 27749953.
      View in: PubMed
    4. Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini SE. Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Sci Rep. 2016 Aug 22; 6:31603. PMID: 27546286; PMCID: PMC4992865.
    5. Didonna A, Benetti F. Post-translational modifications in neurodegeneration. AIMS Biophysics. 2016; 1(3):27-49.
    6. Didonna A. Preclinical Models of Multiple Sclerosis: Advantages and Limitations Towards Better Therapies. Curr Med Chem. 2016; 23(14):1442-59. PMID: 27048376.
      View in: PubMed
    7. Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8. PMID: 26433934; PMCID: PMC5007634 [Available on 12/15/16].
    8. Didonna A, Venturini AC, Hartman K, Vranac T, Curin Šerbec V, Legname G. Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c). PeerJ. 2015; 3:e811. PMID: 25802800; PMCID: PMC4369333.
    9. Didonna A, Oksenberg JR. Genetic determinants of risk and progression in multiple sclerosis. Clin Chim Acta. 2015 Sep 20; 449:16-22. PMID: 25661088; PMCID: PMC4524789 [Available on 09/20/16].
    10. Didonna A, Opal P. The promise and perils of HDAC inhibitors in neurodegeneration. Ann Clin Transl Neurol. 2015 Jan; 2(1):79-101. PMID: 25642438; PMCID: PMC4301678.
    11. Venkatraman A, Hu YS, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, Opal P. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. Hum Mol Genet. 2014 Jul 15; 23(14):3733-45. PMID: 24594842; PMCID: PMC4065149.
    12. Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. J Clin Invest. 2013 May; 123(5):1964-75. PMID: 23585478; PMCID: PMC3635735.
    13. Didonna A. Prion protein and its role in signal transduction. Cell Mol Biol Lett. 2013 Jun; 18(2):209-30. PMID: 23479001.
      View in: PubMed
    14. Didonna A, Sussman J, Benetti F, Legname G. The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells. Prion. 2012 Jul 01; 6(3):309-16. PMID: 22561161; PMCID: PMC3399532.
    15. Didonna A, Vaccari L, Bek A, Legname G. Infrared microspectroscopy: a multiple-screening platform for investigating single-cell biochemical perturbations upon prion infection. ACS Chem Neurosci. 2011 Mar 16; 2(3):160-74. PMID: 22778865; PMCID: PMC3369737.
    16. Didonna A, Legname G. Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells. Mol Neurodegener. 2010 Aug 09; 5:29. PMID: 20696038; PMCID: PMC2928767.
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