Bill Balke, MD
|Title||Professor in Residence|
|School||UCSF School of Medicine|
|Address||185 Berry Street|
San Francisco CA 94143
|Title||Director, Clinical Research Services, CTSI|
Dr. Balke is a clinical and research cardiac electrophysiologist and has maintained a productive basic science and translational research program since the completion of his postdoctoral fellowship. His scientific areas of interest include cardiac arrhythmias, cardiac hypertrophy, and heart failure. His laboratory has made seminal contributions to the understanding of the stochastic relationship of calcium entry during membrane depolarization to the subsequent release of calcium from the sarcoplasmic reticulum in normal and diseased hearts, as supported by manuscripts in the highest quality peer-reviewed journals including Science, the Proceedings of the National Academy of Sciences, and the Journal of Physiology. The NHLBI, the American Heart Association (AHA), and the Veteran’s Affairs Administration (VA) have funded his research program continuously for the last 18 years.
In addition, his research program has provided the platform for mentored experiences for a number of NIH K award (K08, K23, K25, K01) recipients who have gone on to productive careers in academic medicine and industry. This program has also provided the substrate for several NIH-funded institutional training programs in cardiovascular physiology (NIH T32 awards), integrative physiology (NIH T32 award), women’s health (NIH K12 award, Building Interdisciplinary Research Careers in Women’s Health (BIRCWH)) and an NIH Roadmap K12 program (UM) for an interdisciplinary training program to prepare junior faculty for successful careers in clinical and translational research.
As a consequence of these research and mentoring experiences, Dr. Balke has held numerous leadership roles in the NHLBI’s peer-review process, including several terms as a regular member on the former Cardiovascular ‘A’ Study Section, the inaugural chairperson of the Electrical Signaling, Ion Transport and Arrhythmias (ESTA) Study Section, and the inaugural and current chairperson of the Institutional Training Mechanism (T32) Study Section. Through his chairmanship of all the NHLBI’s K award special emphasis panels (Mentored Clinical Scientist Development Program (K08), Mentored Patient-oriented Research Career Development Program (K23), and the Pathway to Independence Award (K99/R00)), he led the initiative to align the policies and approach of these mechanisms to provide a fair, uniform, and transparent process for selecting and supporting the best science and the most deserving investigators in the early stages of their career development. The identification and implementation of best practices in K award evaluation and review has enabled the NHLBI to define a new training paradigm for the academic development of clinically trained investigators, and has ensured the investigator “pipeline” for the future of cardiovascular science.
Dr. Balke has accumulated a unique blend of faculty and senior-level administrative experiences from premier institutions (namely, Johns Hopkins University, University of Pennsylvania, Harvard University, and the University of California San Francisco (UCSF)) with global reputations and missions as well as land grant institutions (University of Maryland (UM) and University of Kentucky (UK)) committed to local and regional missions. These positions represent escalating levels of scope and responsibility, progressing from Chief of the Division of Cardiology and Associate Chairman of the Department of Medicine (UM); Senior Associate Dean for Research, Associate Provost for Clinical and Translational Science, Associate Provost for Academic Planning and Implementation (UK); to his current position as Program Director of the Clinical Research Center and member of the Board of Directors of the UCSF Clinical and Translational Science Institute (CTSI).
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