Bo Huang, PhD
|School||UCSF School of Pharmacy|
|Address||1700 4th Street|
San Francisco CA 94158
|2011||NIH Director's New Innovator Award|
|2010||Packard Fellowship for Science and Engineering|
|2007||GE & Science Young Life Scientist Award, North America Regional Winner|
||2004||Stanford Graduate Fellowship|
|2006||Annual Reviews Prize in Physical Chemistry, Stanford University|
The vast majority of biological processes inside a cell are carried out by the coordinated participation of many proteins. Our research focuses on understanding the mechanisms that enable them to work together. By developing and applying new approaches based on super-resolution microscopy and single-molecule imaging, we are interested in answering three questions: (1) how proteins organize into large complexes such as the nuclear pore complex and centrosome, (2) how proteins dynamically interact with each other to regulate cell signaling, especially in the G-protein coupled receptor pathway, and for cell adhesion molecules to control the development of the nervous system, and (3) how protein and DNA interact each other in the nucleus. We are also interested in combining synthetic chemistry, protein engineering and microfluidics-based high-throughput screening to create new fluorescent probes that allow us to better study these cellular structures and processes.
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