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Bruce Wintroub, MD

TitleVice Dean of the School of Medicine
SchoolUCSF School of Medicine
DepartmentDermatology
Address1701 Divisadero
San Francisco CA 94115
Phone415-353-7597
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    Other Positions
    TitleChair, Dermatology

    TitleProfessor


    Collapse Biography 
    Collapse Education and Training
    Washington UniversityM.D.1969School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    HUMAN SKIN MAST CELL GRANULE ENZYMES--SKIN DISEASES
    NIH/NIAMS R01AR031901Jul 1, 1982 - Mar 31, 1994
    Role: Principal Investigator
    ANGIOTENSINS IN CUTANEOUS INFLAMMATION &DISEASE
    NIH/NIADDK R01AM031901Jul 1, 1982 - Dec 31, 1987
    Role: Principal Investigator

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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pandya AG, Alexis AF, Berger TG, Wintroub BU. Increasing racial and ethnic diversity in dermatology: A call to action. J Am Acad Dermatol. 2016 Mar; 74(3):584-7. PMID: 26774427.
      View in: PubMed
    2. Fairley JA, Krueger GG, Lessin SR, Leyden JJ, McBurney EI, Orlow SJ, Tharp MD, Voorhees JJ, Wintroub BU, Yancey KB. The Dermatology Foundation: partnerships and programs focused on the future. J Invest Dermatol. 2013 Apr; 133(4):861-2. PMID: 23486423.
      View in: PubMed
    3. Boris C, Lessin SR, Wintroub BU, Yancey KB. A retrospective analysis of the Dermatology Foundation's Career Development Award Program. J Am Acad Dermatol. 2012 Nov; 67(5):969-74. PMID: 22459361.
      View in: PubMed
    4. Callen J, Chamlin S, Eichenfield LF, Ellis C, Girardi M, Goldfarb M, Hanifin J, Lee P, Margolis D, Paller AS, Piacquadio D, Peterson W, Kaulback K, Fennerty M, Wintroub BU. A systematic review of the safety of topical therapies for atopic dermatitis. Br J Dermatol. 2007 Feb; 156(2):203-21. PMID: 17223859.
      View in: PubMed
    5. Wintroub BU. Dermatology, the academic medical center, and the new millennium. Arch Dermatol. 1999 Oct; 135(10):1264-5. PMID: 10522676.
      View in: PubMed
    6. Shupack J, Abel E, Bauer E, Brown M, Drake L, Freinkel R, Guzzo C, Koo J, Levine N, Lowe N, McDonald C, Margolis D, Stiller M, Wintroub B, Bainbridge C, Evans S, Hilss S, Mietlowski W, Winslow C, Birnbaum JE. Cyclosporine as maintenance therapy in patients with severe psoriasis. J Am Acad Dermatol. 1997 Mar; 36(3 Pt 1):423-32. PMID: 9091474.
      View in: PubMed
    7. Bolognia JL, Wintroub BU. The impact of managed care on graduate medical education and academic medical centers. Arch Dermatol. 1996 Sep; 132(9):1078-84. PMID: 8795549.
      View in: PubMed
    8. Heald P, Rook A, Perez M, Wintroub B, Knobler R, Jegasothy B, Gasparro F, Berger C, Edelson R. Treatment of erythrodermic cutaneous T-cell lymphoma with extracorporeal photochemotherapy. J Am Acad Dermatol. 1992 Sep; 27(3):427-33. PMID: 1401279.
      View in: PubMed
    9. Natsuaki M, Stewart CB, Vanderslice P, Schwartz LB, Natsuaki M, Wintroub B, Rutter WJ, Goldstein SM. Human skin mast cell carboxypeptidase: functional characterization, cDNA cloning, and genealogy. J Invest Dermatol. 1992 Aug; 99(2):138-45. PMID: 1629626.
      View in: PubMed
    10. Zackheim HS, Springer EA, Brown PJ, Wintroub B, Clendeninn NJ. A pilot study of piritrexim in mycosis fungoides. Arch Dermatol. 1992 Apr; 128(4):561-2. PMID: 1580670.
      View in: PubMed
    11. Rook AH, Freundlich B, Jegasothy BV, Perez MI, Barr WG, Jimenez SA, Rietschel RL, Wintroub B, Kahaleh MB, Varga J. Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial. Arch Dermatol. 1992 Mar; 128(3):337-46. PMID: 1550365.
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    12. Irani AM, Goldstein SM, Wintroub B, Bradford T, Schwartz LB. Human mast cell carboxypeptidase. Selective localization to MCTC cells. J Immunol. 1991 Jul 1; 147(1):247-53. PMID: 2051021.
      View in: PubMed
    13. Schechter NM, Irani AM, Sprows JL, Abernethy J, Wintroub B, Schwartz LB. Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell. J Immunol. 1990 Oct 15; 145(8):2652-61. PMID: 2212656.
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    14. Weiss TL, Selleck SE, Reusch M, Wintroub B. Serial subculture and relative transport of human endothelial cells in serum-free, defined conditions. In Vitro Cell Dev Biol. 1990 Aug; 26(8):759-68. PMID: 2168366.
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    15. Goldstein SM, Kaempfer CE, Wintroub B. Human mast cell carboxypeptidase. Monogr Allergy. 1990; 27:132-45. PMID: 2084535.
      View in: PubMed
    16. Halberg FE, Fu KK, Weaver KA, Zackheim HS, Epstein EH, Wintroub B. Combined total body X-ray irradiation and total skin electron beam radiotherapy with an improved technique for mycosis fungoides. Int J Radiat Oncol Biol Phys. 1989 Aug; 17(2):427-32. PMID: 2666369.
      View in: PubMed
    17. Hunziker T, Boillat C, Gerber HA, Wiesmann U, Wintroub B. In vitro pemphigus vulgaris model using organotypic cultures of human epidermal keratinocytes. J Invest Dermatol. 1989 Aug; 93(2):263-7. PMID: 2474033.
      View in: PubMed
    18. Goldstein SM, Kaempfer CE, Kealey JT, Wintroub B. Human mast cell carboxypeptidase. Purification and characterization. J Clin Invest. 1989 May; 83(5):1630-6. PMID: 2708524; PMCID: PMC303870.
    19. Weiss TL, Barker ME, Selleck SE, Wintroub B. Erythropoietin binding and induced differentiation of Rauscher erythroleukemia cell line red 5-1.5. J Biol Chem. 1989 Jan 25; 264(3):1804-10. PMID: 2463988.
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    20. Goldstein SM, Wasserman SI, Wintroub BU. Mast cell and eosinophil mediated damage in bullous pemphigoid. Immunol Ser. 1989; 46:527-45. PMID: 2484955.
      View in: PubMed
    21. Goldstein SM, Kaempfer CE, Wintroub B. Mast cell carboxypeptidase: biochemistry and biology. Prog Clin Biol Res. 1989; 297:145-54. PMID: 2685818.
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    22. Goldstein SM, Kaempfer CE, Proud D, Schwartz LB, Irani AM, Wintroub B. Detection and partial characterization of a human mast cell carboxypeptidase. J Immunol. 1987 Oct 15; 139(8):2724-9. PMID: 2443571.
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    23. Dzau VJ, Gonzalez D, Kaempfer C, Dubin D, Wintroub BU. Human neutrophils release serine proteases capable of activating prorenin. Circ Res. 1987 Apr; 60(4):595-601. PMID: 3297385.
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    24. Edelson R, Berger C, Gasparro F, Jegasothy B, Heald P, Wintroub B, Vonderheid E, Knobler R, Wolff K, Plewig G. Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results. N Engl J Med. 1987 Feb 5; 316(6):297-303. PMID: 3543674.
      View in: PubMed
    25. Wintroub BU, Wasserman SI. The molecular pathogenesis of bullous pemphigoid. Clin Dermatol. 1987 Jan-Mar; 5(1):126-34. PMID: 3552182.
      View in: PubMed
    26. Stern RS, Wintroub B. Adverse drug reactions: reporting and evaluating cutaneous reactions. Adv Dermatol. 1987; 2:3-17. PMID: 2978937.
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    27. Stern RS, Wintroub B, Arndt KA. Drug reactions. J Am Acad Dermatol. 1986 Dec; 15(6):1282-8. PMID: 2948975.
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    28. LeBoit PE, Yen TS, Wintroub B. The evolution of lesions in erythema elevatum diutinum. Am J Dermatopathol. 1986 Oct; 8(5):392-402. PMID: 3777377.
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    29. Snyder RA, Wintroub B. Inhibition of angiotensin-converting enzyme by des-Leu10-angiotensin I: a potential mechanism of endogenous angiotensin-converting enzyme regulation. Biochim Biophys Acta. 1986 May 12; 871(1):1-5. PMID: 3008847.
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    30. Wintroub BU, Kaempfer CE, Schechter NM, Proud D. A human lung mast cell chymotrypsin-like enzyme. Identification and partial characterization. J Clin Invest. 1986 Jan; 77(1):196-201. PMID: 3511089; PMCID: PMC423327.
    31. Burrall BA, Wintroub BU, Goetzl EJ. Selective expression of 15-lipoxygenase activity by cultured human keratinocytes. Biochem Biophys Res Commun. 1985 Nov 27; 133(1):208-13. PMID: 3935111.
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    32. Grayson S, Johnson-Winegar AG, Wintroub BU, Isseroff RR, Epstein EH, Elias PM. Lamellar body-enriched fractions from neonatal mice: preparative techniques and partial characterization. J Invest Dermatol. 1985 Oct; 85(4):289-94. PMID: 4045217.
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    33. Schwartz LB, Bradford TR, Littman BH, Wintroub B. The fibrinogenolytic activity of purified tryptase from human lung mast cells. J Immunol. 1985 Oct; 135(4):2762-7. PMID: 3161948.
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    34. Wintroub B, Stern R. Cutaneous drug reactions: pathogenesis and clinical classification. J Am Acad Dermatol. 1985 Aug; 13(2 Pt 1):167-79. PMID: 2931455.
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    35. Snyder RA, Watt KW, Wintroub B. A human platelet angiotensin I-processing system. Identification of components and inhibition of angiotensin-converting enzyme by product. J Biol Chem. 1985 Jul 5; 260(13):7857-60. PMID: 2989263.
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    36. Epstein JH, Wintroub BU. Photosensitivity due to drugs. Drugs. 1985 Jul; 30(1):42-57. PMID: 3896743.
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    37. Koch SE, Wintroub BU. Pott's puffy tumor. A clinical marker for osteomyelitis of the skull. Arch Dermatol. 1985 Apr; 121(4):548-9. PMID: 3977381.
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    38. Snyder RA, Kaempfer CE, Wintroub B. Chemistry of a human monocyte-derived cell line (U937): identification of the angiotensin I-converting activity as leukocyte cathepsin G. Blood. 1985 Jan; 65(1):176-82. PMID: 2981131.
      View in: PubMed
    39. Wintroub BU, Schechter NB, Lazarus GS, Kaempfer CE, Schwartz LB. Angiotensin I conversion by human and rat chymotryptic proteinases. J Invest Dermatol. 1984 Nov; 83(5):336-9. PMID: 6092480.
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    40. Borton LK, Wintroub BU. Disseminated cryptococcosis presenting as herpetiform lesions in a homosexual man with acquired immunodeficiency syndrome. J Am Acad Dermatol. 1984 Feb; 10(2 Pt 2):387-90. PMID: 6707261.
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    41. Wintroub BU, Klickstein LB, Dzau VJ, Watt KW. Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G. Biochemistry. 1984 Jan 17; 23(2):227-32. PMID: 6696878.
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    42. Margolis RJ, Tonnesen MG, Harrist TJ, Bhan AK, Wintroub BU, Mihm MC, Soter NA. Lymphocyte subsets and Langerhans cells/indeterminate cells in erythema multiforme. J Invest Dermatol. 1983 Nov; 81(5):403-6. PMID: 6631050.
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    43. Center DM, Wintroub BU, Austen KF. Identification of chemoattractant activity for lymphocytes in blister fluid of patients with bullous pemphigoid: evidence for the presence of a lymphokine. J Invest Dermatol. 1983 Sep; 81(3):204-8. PMID: 6350481.
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    44. Branch WT, Wintroub BU. Dermatologic training for nondermatologists. J Am Acad Dermatol. 1983 Aug; 9(2):281-3. PMID: 6886124.
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    45. Tonnesen MG, Harrist TJ, Wintroub BU, Mihm MC, Soter NA. Erythema multiforme: microvascular damage and infiltration of lymphocytes and basophils. J Invest Dermatol. 1983 Apr; 80(4):282-6. PMID: 6339644.
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    46. Branch WT, Collins M, Wintroub BU. Dermatologic practice: implications for a primary care residency curriculum. J Med Educ. 1983 Feb; 58(2):136-42. PMID: 6822984.
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    47. Klickstein LB, Kaempfer CE, Wintroub BU. The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G. J Biol Chem. 1982 Dec 25; 257(24):15042-6. PMID: 6294088.
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    48. Dvorak AM, Mihm MC, Osage JE, Kwan TH, Austen KF, Wintroub BU. Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient. J Invest Dermatol. 1982 Feb; 78(2):91-101. PMID: 7035575.
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    49. Klickstein LB, Wintroub BU. Separation of angiotensins and assay of angiotensin-generating enzymes by high-performance liquid chromatography. Anal Biochem. 1982 Feb; 120(1):146-50. PMID: 6283931.
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    50. Tonnesen MG, Klempner MS, Austen KF, Wintroub BU. Identification of a human neutrophil angiotension II-generating protease as cathepsin G. J Clin Invest. 1982 Jan; 69(1):25-30. PMID: 6172448; PMCID: PMC371164.
    51. Wintroub BU, Klickstein LB, Watt KW. A human neutrophil-dependent pathway for generation of angiotensin II. Purification of the product and identification as angiotensin II. J Clin Invest. 1981 Aug; 68(2):484-90. PMID: 7021592; PMCID: PMC370822.
    52. Wintroub BU, Mihm MC. Mast cell-dependent effector pathways and cutaneous bullous disorders. Springer Semin Immunopathol. 1981 Jun; 4(1):65-72. PMID: 7022723.
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    53. Wintroub BU, Soter NA. Biology of the mast cell and its role in cutaneous inflammation. Springer Semin Immunopathol. 1981 Jun; 4(1):55-63. PMID: 7022722.
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    54. Wintroub BU, Klickstein LB, Kaempfer CE, Austen KF. A human neutrophil-dependent pathway for generation of angiotensin II: purification and physicochemical characterization of the plasma protein substrate. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):1204-8. PMID: 6785751; PMCID: PMC319976.
    55. Goetzl EJ, Klickstein LB, Watt KW, Wintroub BU. The preferential human mononuclear leukocyte chemotactic activity of the substituent tetrapeptides of angiotensin II. Biochem Biophys Res Commun. 1980 Dec 16; 97(3):1097-102. PMID: 7470137.
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    56. Wintroub BU. Inflammation and mediators. Int J Dermatol. 1980 Oct; 19(8):436-42. PMID: 6109697.
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    57. Wintroub BU, Coblyn JS, Kaempfer CE, Austen KF. Cleavage of fibrinogen by the human neutrophil neutral peptide-generating protease. Proc Natl Acad Sci U S A. 1980 Sep; 77(9):5448-52. PMID: 7001479; PMCID: PMC350077.
    58. Coblyn JS, Austen KF, Wintroub BU. Purification and characterization of a human neutrophil neutral protease. The neutral peptide-generating protease. J Clin Invest. 1979 May; 63(5):998-1005. PMID: 36407; PMCID: PMC372041.
    59. Wintroub B, Mihm MC, Goetzl EJ, Soter NA, Austen KF. Morphologic and functional evidence for release of mast-cell products in bullous pemphigoid. N Engl J Med. 1978 Feb 23; 298(8):417-21. PMID: 340950.
      View in: PubMed
    60. Center DM, Austen KF, Wintroub B. Identification of chemoattractant activity for lymphocytes in bullous pemphigoid bullous fluid. Trans Assoc Am Physicians. 1978; 91:242-52. PMID: 382589.
      View in: PubMed
    61. Wintroub B, Goetzl EJ, Austen KF. A neutrophil-dependent pathway for the generation of a neutral peptide mediator. II. Subcellular localization of the neutrophil protease. Immunology. 1977 Jul; 33(1):41-9. PMID: 873575; PMCID: PMC1445417.
    62. Gigli I, Wintroub B, Goetzl EJ. A phagocytosis-enhancing factor in human plasma. Immunology. 1976 Jun; 30(6):915-24. PMID: 1027715; PMCID: PMC1445077.
    63. Wintroub BU, Goetzl EJ, Austen KF. A neutrophil-dependent pathway for the generation of a neutral peptide mediator: partial characterization of components and control by alpha-1-antitrypsin. J Exp Med. 1974 Sep 1; 140(3):812-24. PMID: 4547125; PMCID: PMC2139623.
    64. Wintroub BU, Schroeder JS, Schroll M, Robison SL, Harrison DC. Hemodynamic response to dopamine in experimental myocardial infarction. Am J Physiol. 1969 Dec; 217(6):1716-20. PMID: 5353047.
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    65. Harrison DC, Pirages S, Robison SC, Wintroub BU. The pulmonary and systemic circulatory response to dopamine infusion. Br J Pharmacol. 1969 Nov; 37(3):618-26. PMID: 5348465; PMCID: PMC1703725.
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