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    Carina Mari Aparici, MD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    Address4150 Clement St, Bldg 13
    San Francisco CA 94121
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      Collapse Biography 
      Collapse Education and Training
      Universidad de ValenciaM.D.School of Medicine1992
      Collapse Awards and Honors
      Ongology Outreach Group, the Targeted Radiotreatment Outreach Working Group, Society of NM and MI2013Board Member, Outreach Council, and Co-Chair
      Society of Computed Body Tomography and Magnetic Resonance2012Finalist Poster Award
      Association of University Radiologists (AUR)20123rd Place Trainee Prize
      Society of Nuclear Medicine and Molecular Imaging2011Finalists in the EDUCATIONAL EXHIBITS
      University of California, San Francisco2009Haile T. Debas Academy of Medical Educators Excellence in Teaching Award
      Society of Nuclear Medicine and Molecular Imaging2008Young Professional Award
      SNM Annual Western Regional Meeting 2007Best in training abstract
      ISS/NIH Collaborative Programme2006Plenary Lecture Cardiovascular
      SEMN 2005Plenary Session
      Radiological Society of North America2005Trainee Research Prize: Winner
      Society of Nuclear Medicine and Molecular Imaging2002Cardiovascular Young Investigator Award
      European Association of Nuclear Medicine (EANM)2000Nominated for the Madam Curie Award
      Society of Nuclear Medicine (SNM)1999Nominated for Cardiovascular Young Investigator Award
      European Association of Nuclear Medicine (EANM)1999Nominated for the Madam Curie Award

      Collapse Overview 
      Collapse Overview
      Carina Mari Aparici, MD, is an Associate Professor in Residence in the Department of Radiology at the University of California, San Francisco. Since 2005, Dr. Aparici serves as the Chief of Nuclear Medicine at the San Francisco Veterans Affairs Hospital.

      Nuclear Medicine

      Molecular Imaging, PET/CT, SPECT/CT, small animal imaging, preclinical ad clinical research

      Professional Interests:
      Molecular imaging, positron emission tomography (PET), single photon emission tomography (SPECT), dual modality imaging (hybrid imaging) PET/CT and SPECT/CT, apoptosis, atherosclerosis, vulnerable plaque, intravascular catheter, cardiovascular disease, heart transplant, lymphoscintigraphy, sentinel node, NIS (Sodium/Iodine symporter), molecular targeted treatment, translational research, molecular imaging of the brain.

      Education and Training:
      • Medical School: University of Valencia (UV) School of Medicine, Spain
      • Doctorate Degree: Univeristy of Valencia, Spain
      • Doctorate Degree: Autonomous University of Barcelona (UAB), Spain
      • Master Degree: Autonomous University of Barcelona, Spain
      • Residency: Sant Pau Hospital School of Medicine, UAB, Spain - Nuclear Medicine
      • Residency: Stanford University, California - Nuclear Medicine
      • Fellowship: Stanford University, California - Cardiovascular Nuclear Molecular Imaging
      • Fellowship: Stanford University, California - Breast Cancer Molecular Imaging
      • Fellowship: Stanford University, California - Basic Science Molecular Imaging
      • American Board of Nuclear Medicine
      • Medical License in California
      • BLS certified
      • ACLS certified

      Collapse Interests
      Molecular imaging, positron emission tomography (PET), single photon emission tomography (SPECT), dual modality imaging (hybrid imaging) PET/CT and SPECT/CT, apoptosis, atherosclerosis, vulnerable plaque, intravascular catheter, cardiovascular disease, heart transplant, lymphoma, lymphoscintigraphy, sentinel node, NIS (Sodium/Iodine symporter), molecular targeted treatment, translational research.

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Win A., Mari C. . Journal of Biomedical Graphics and Computing. "Heterogeneous osteoblastic activity in the right ischium of unclear etiology seen on NaF18-PET/CT". 2013; 3(1).
      2. Mari Aparici C, Seo Y. Functional imaging for prostate cancer: therapeutic implications. Semin Nucl Med. 2012 Sep; 42(5):328-42. PMID: 22840598; PMCID: PMC3408625.
      3. Do BH, Mari C, Tseng JR, Quon A, Rosenberg J, Biswal S. Pattern of 18F-FDG uptake in the spinal cord in patients with non-central nervous system malignancy. Spine (Phila Pa 1976). 2011 Oct 1; 36(21):E1395-401. PMID: 21311407.
        View in: PubMed
      4. Taggart DR, Han MM, Quach A, Groshen S, Ye W, Villablanca JG, Jackson HA, Mari Aparici C, Carlson D, Maris J, Hawkins R, Matthay KK. Comparison of iodine-123 metaiodobenzylguanidine (MIBG) scan and [18F]fluorodeoxyglucose positron emission tomography to evaluate response after iodine-131 MIBG therapy for relapsed neuroblastoma. J Clin Oncol. 2009 Nov 10; 27(32):5343-9. PMID: 19805691; PMCID: PMC2773221.
      5. Franc BL, Acton PD, Mari C, Hasegawa BH. Small-animal SPECT and SPECT/CT: important tools for preclinical investigation. J Nucl Med. 2008 Oct; 49(10):1651-63. PMID: 18794275.
        View in: PubMed
      6. Iagaru A, Wang Y, Mari C, Quon A, Goris ML, Horning S, Gambhir SS. (18)F-FDG-PET/CT evaluation of response to treatment in lymphoma: when is the optimal time for the first re-evaluation scan? Hell J Nucl Med. 2008 Sep-Dec; 11(3):153-6. PMID: 19081857.
        View in: PubMed
      7. Seo Y, Mari C, Hasegawa BH. Technological development and advances in single-photon emission computed tomography/computed tomography. Semin Nucl Med. 2008 May; 38(3):177-98. PMID: 18396178; PMCID: PMC3049175.
      8. Iagaru A, Mari C, Sam Gambhir S. Follicular dendritic sarcoma within a focus of Castleman's disease. Serial FDG PET/CT in the follow up of recurrence with histopathologic confirmation. Rev Esp Med Nucl. 2007 Jan-Feb; 26(1):40-5. PMID: 17286947.
        View in: PubMed
      9. Mari Aparici C. [Introduction to the molecular imaging]. Rev Esp Med Nucl. 2006 Nov-Dec; 25(6):394-409. PMID: 17173791.
        View in: PubMed
      10. Iagaru A, Mari C, Segall G. F-18 FDG PET evaluation of bronchial plasmacytoma with CT and MRI correlation. Clin Nucl Med. 2006 May; 31(5):279-80. PMID: 16622337.
        View in: PubMed
      11. Strauss HW, Mari C, Patt BE, Ghazarossian V. Intravascular radiation detectors for the detection of vulnerable atheroma. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C97-100. PMID: 16631517.
        View in: PubMed
      12. Do B, Mari C, Biswal S, Kalinyak J, Quon A, Gambhir SS. Diagnosis of aseptic deep venous thrombosis of the upper extremity in a cancer patient using fluorine-18 fluorodeoxyglucose positron emission tomography/computerized tomography (FDG PET/CT). Ann Nucl Med. 2006 Feb; 20(2):151-5. PMID: 16615425.
        View in: PubMed
      13. Franc BL, Mari C, Johnson D, Leong SP. The role of a positron- and high-energy gamma photon probe in intraoperative localization of recurrent melanoma. Clin Nucl Med. 2005 Dec; 30(12):787-91. PMID: 16319633.
        View in: PubMed
      14. Cowan CM, Aalami OO, Shi YY, Chou YF, Mari C, Thomas R, Quarto N, Nacamuli RP, Contag CH, Wu B, Longaker MT. Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover. Tissue Eng. 2005 Mar-Apr; 11(3-4):645-58. PMID: 15869441.
        View in: PubMed
      15. Blankenberg FG, Mandl S, Cao YA, O'Connell-Rodwell C, Contag C, Mari C, Gaynutdinov TI, Vanderheyden JL, Backer MV, Backer JM. Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor. J Nucl Med. 2004 Aug; 45(8):1373-80. PMID: 15299064.
        View in: PubMed
      16. Fong KD, Song HM, Nacamuli RP, Franc BL, Mari C, Fang TD, Warren SM, Contag CH, Blankenberg FG, Longaker MT. Apoptosis in a rodent model of cranial suture fusion: in situ imaging and gene expression analysis. Plast Reconstr Surg. 2004 Jun; 113(7):2037-47. PMID: 15253194.
        View in: PubMed
      17. Cowan CM, Shi YY, Aalami OO, Chou YF, Mari C, Thomas R, Quarto N, Contag CH, Wu B, Longaker MT. Adipose-derived adult stromal cells heal critical-size mouse calvarial defects. Nat Biotechnol. 2004 May; 22(5):560-7. PMID: 15077117.
        View in: PubMed
      18. Mari C, Karabiyikoglu M, Goris ML, Tait JF, Yenari MA, Blankenberg FG. Detection of focal hypoxic-ischemic injury and neuronal stress in a rodent model of unilateral MCA occlusion/reperfusion using radiolabeled annexin V. Eur J Nucl Med Mol Imaging. 2004 May; 31(5):733-9. PMID: 14985868.
        View in: PubMed
      19. Mandl SJ, Mari C, Edinger M, Negrin RS, Tait JF, Contag CH, Blankenberg FG. Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome. Mol Imaging. 2004 Jan; 3(1):1-8. PMID: 15142407.
        View in: PubMed
      20. Blankenberg F, Mari C, Strauss HW. Imaging cell death in vivo. Q J Nucl Med. 2003 Dec; 47(4):337-48. PMID: 14973423.
        View in: PubMed
      21. Estorch M, Tembl A, Antonijoan R, Hernandez A, Mari C, Flotats A, Camacho V, Sola R, Barbanoj M, Carrio I. Evaluation of renal graft haemodynamia by 51Cr-EDTA and o-[131I]iodohippurate: its use in the early diagnosis of glomerular hyperfiltration. Nucl Med Commun. 2003 Jun; 24(6):679-82. PMID: 12766604.
        View in: PubMed
      22. Kown MH, Murata S, Jahncke CL, Mari C, Berry GJ, Lijkwan MA, Blankenberg FG, Strauss HW, Robbins RC. Donor cardiac allografts from p53 knockout mice exhibit apoptosis-independent prolongation of survival. Transplant Proc. 2002 Dec; 34(8):3274-6. PMID: 12493444.
        View in: PubMed
      23. Kown MH, Jahncke CL, Lijkwan MA, Koransky ML, Mari C, Berry GJ, Blankenberg FG, Strauss HW, Robbins RC. The use of (99m)technetium-labeled MCP-1 to assess graft coronary artery disease in rat cardiac allografts. J Heart Lung Transplant. 2002 Sep; 21(9):1009-15. PMID: 12231372.
        View in: PubMed
      24. Mari C, Strauss HW. Radiotracer characterization of coronary artery lesions. Nucl Med Commun. 2002 Aug; 23(8):703-6. PMID: 12124473.
        View in: PubMed
      25. Mari C, Strauss WH. Detection and characterization of hibernating myocardium. Nucl Med Commun. 2002 Apr; 23(4):311-22. PMID: 11930184.
        View in: PubMed
      26. Kown MH, van der Steenhoven TJ, Jahncke CL, Mari C, Lijkwan MA, Koransky ML, Blankenberg FG, Strauss HW, Robbins RC. Zinc chloride-mediated reduction of apoptosis as an adjunct immunosuppressive modality in cardiac transplantation. J Heart Lung Transplant. 2002 Mar; 21(3):360-5. PMID: 11897525.
        View in: PubMed
      27. Blankenberg FG, Mari C, Strauss HW. Development of radiocontrast agents for vascular imaging: progress to date. Am J Cardiovasc Drugs. 2002; 2(6):357-65. PMID: 14727951.
        View in: PubMed
      28. Martí-Fàbregas JA, Catafau AM, Marí C, Mendoza G, Sanahuja J, Lleó A, Martí-Vilalta JL. Cerebral perfusion and haemodynamics measured by SPET in symptom-free patients with transient ischaemic attack: clinical implications. Eur J Nucl Med. 2001 Dec; 28(12):1828-35. PMID: 11734922.
        View in: PubMed
      29. Estorch M, Narula J, Flotats A, Marí C, Tembl A, Martín JC, del Valle Camacho M, Catafau AM, Serra-Grima R, Carrió I. Concordance between rest MIBG and exercise tetrofosmin defects: possible use of rest MIBG imaging as a marker of reversible ischaemia. Eur J Nucl Med. 2001 May; 28(5):614-9. PMID: 11383867.
        View in: PubMed
      30. Tembl A, Bernà L, Camacho V, Martín JC, Marí C, Flotats A. [67 Ga-citrate scintigraphy as a determiner in the diagnosis of a subacute thyroiditis]. Rev Esp Med Nucl. 2001 Feb; 20(1):36-9. PMID: 11181329.
        View in: PubMed
      31. Estorch M, Serra-Grima R, Flotats A, Marí C, Bernà L, Catafau A, Martín JC, Tembl A, Narula J, Carrió I. Myocardial sympathetic innervation in the athlete's sinus bradycardia: is there selective inferior myocardial wall denervation? J Nucl Cardiol. 2000 Jul-Aug; 7(4):354-8. PMID: 10958277.
        View in: PubMed
      32. Estorch M, Flotats A, Serra-Grima R, Mari C, Prat T, Martín JC, Bernà L, Catafau AM, Tembl A, Carrió I. Influence of exercise rehabilitation on myocardial perfusion and sympathetic heart innervation in ischaemic heart disease. Eur J Nucl Med. 2000 Mar; 27(3):333-9. PMID: 10774887.
        View in: PubMed
      33. Marí C, León J, Farrerons J, Matis-Guiu X, Tembl A, Martin JC, Flotats A, Bernà Ll. Thymic carcinoid and parathyroid hyperplasia detection with 99mTc-MIBI men type 1. J Endocrinol Invest. 1999 Nov; 22(10):803-7. PMID: 10614532.
        View in: PubMed
      34. Marì C, Catafau A, Carriò I. Bone scintigraphy and metabolic disorders. Q J Nucl Med. 1999 Sep; 43(3):259-67. PMID: 10568141.
        View in: PubMed
      35. Estorch M, Campreciós M, Flotats A, Marí C, Bernà L, Catafau AM, Ballester M, Narula J, Carrió I. Sympathetic reinnervation of cardiac allografts evaluated by 123I-MIBG imaging. J Nucl Med. 1999 Jun; 40(6):911-6. PMID: 10452305.
        View in: PubMed
      36. Catafau AM, Etcheberrigaray A, Perez de los Cobos J, Estorch M, Guardia J, Flotats A, Bernà L, Marí C, Casas M, Carrió I. Regional cerebral blood flow changes in chronic alcoholic patients induced by naltrexone challenge during detoxification. J Nucl Med. 1999 Jan; 40(1):19-24. PMID: 9935051.
        View in: PubMed
      37. Bernà L, Chico A, Matías-Guiu X, Mato E, Catafau A, Alonso C, Mora J, Mauricio D, Rodríguez-Espinosa J, Marí C, Flotats A, Martín JC, Estorch M, Carrió I. Use of somatostatin analogue scintigraphy in the localization of recurrent medullary thyroid carcinoma. Eur J Nucl Med. 1998 Nov; 25(11):1482-8. PMID: 9799343.
        View in: PubMed
      38. Flotats A, I. Carrió, M. Estorch, Ll. Bernà, A. Catafau, Marí Aparici C, M, Ballester. . . Rev Esp Cardiol. “Evaluation of myocardial viability using perfusion cardiac SPECT Thallium-201 rest/redistribucion, tetrofosmin rest/post-nitrates”. 1998; (Supl 1):(51):45-52..
      39. Flotats A, Carrió I, Estorch M, Bernà L, Catafau AM, Marí C, Ballester M. Nitrate administration to enhance the detection of myocardial viability by technetium-99m tetrofosmin single-photon emission tomography. Eur J Nucl Med. 1997 Jul; 24(7):767-73. PMID: 9211763.
        View in: PubMed
      40. Marí C, A. Flotats, Ll. Bernà, M. Estorch, A. Catafau, I. Carrió. . Rev Esp Med Nuclear. “111-pentetreotide in the diagnostic localization of recurrence in medullary thyroid cancer”. 1997; 16(5):316-320.
      41. Flotats A, Carrió I, Estorch M, Bernà L, Catafau A, Marí C, M, Ballester. . Rev Esp Med Nuclear. “Nitrate administration improves the detection of myocardial viability with cardiac SPECT using 99mTc-tetrofosmin”. 1997; 2(16):91-98.
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