Carol Gross, PhD

Title(s)Professor, Cell and Tissue Biology
SchoolSchool of Dentistry
Address600 16th St, #S372E
San Francisco CA 94158
Phone415-476-1493
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    Collapse Research 
    Collapse Research Activities and Funding
    The Bacterial Cell Envelope: From Mechanism of Assembly to Role in the Physiology of single cells and communities
    NIH R13AI140634Jun 15, 2018 - May 31, 2019
    Role: Principal Investigator
    Cellular homeostasis pathways in bacteria
    NIH R35GM118061Jun 7, 2016 - Jun 30, 2026
    Role: Principal Investigator
    Gene Function and Pathway Analysis Using Systems Level Approaches in Prokaryotes
    NIH R01GM102790Aug 13, 2012 - Jun 30, 2016
    Role: Principal Investigator
    Global Genetic Interaction Profiling in Prokaryotes
    NIH R01GM085697Sep 25, 2008 - Jul 31, 2012
    Role: Principal Investigator
    Protein Folding in the Cell
    NIH R13GM085824Jul 1, 2008 - Jun 30, 2013
    Role: Co-Principal Investigator
    FASEB Conference-Mechanism and Regulation of Prokaryotic Transcription
    NIH R13GM075724Jun 15, 2005 - Jun 14, 2006
    Role: Principal Investigator
    2004 Microbial Stress Response Gordon Conference
    NIH R13GM071724Jul 1, 2004 - Jun 30, 2005
    Role: Principal Investigator
    Regulation of the Heat Shock Response in E. Coli
    NIH R01GM036278Jan 1, 1986 - Jan 31, 2017
    Role: Principal Investigator
    REGULATION OF THE HEAT SHOCK RESPONSE IN E. COLI
    NIH R37GM036278Jan 1, 1986 - Dec 31, 2004
    Role: Principal Investigator
    A MUTATIONAL ANALYSIS OF E COLI RNA POLYMERASE
    NIH K04AI000573Jul 1, 1984 - Jun 30, 1989
    Role: Principal Investigator
    Mutational Analysis of E. Coli Core RNA Polymerase
    NIH R01GM057755Jan 1, 1983 - Jul 31, 2015
    Role: Principal Investigator
    MUTATIONAL ANALYSIS OF E COLI CORE RNA POLYMERASE
    NIH R01AI019635Jan 1, 1983 - Nov 30, 1997
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evelyn Witkin: Pioneering DNA repair researcher and social justice activist. Mol Cell. 2023 Oct 19; 83(20):3575-3577. Gross CA, Walker GC. PMID: 37863023.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Three Bacterial DedA Subfamilies with Distinct Functions and Phylogenetic Distribution. mBio. 2023 04 25; 14(2):e0002823. Todor H, Herrera N, Gross CA. PMID: 36856409; PMCID: PMC10127716.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Three bacterial DedA subfamilies with distinct functions and phylogenetic distribution. bioRxiv. 2023 Jan 05. Todor H, Herrera N, Gross C. PMID: 36712119; PMCID: PMC9881974.
      View in: PubMed   Mentions:
    4. Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms. mBio. 2022 02 22; 13(1):e0272621. Mitchell G, Silvis MR, Talkington KC, Budzik JM, Dodd CE, Paluba JM, Oki EA, Trotta KL, Licht DJ, Jimenez-Morales D, Chou S, Savage PB, Gross CA, Marletta MA, Cox JS. PMID: 35073755; PMCID: PMC8787472.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    5. The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation. Proc Natl Acad Sci U S A. 2022 01 25; 119(4). Zhang Y, Aleksashin NA, Klepacki D, Anderson C, Vázquez-Laslop N, Gross CA, Mankin AS. PMID: 35064089; PMCID: PMC8794815.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    6. Morphological and Transcriptional Responses to CRISPRi Knockdown of Essential Genes in Escherichia coli. mBio. 2021 10 26; 12(5):e0256121. Silvis MR, Rajendram M, Shi H, Osadnik H, Gray AN, Cesar S, Peters JM, Hearne CC, Kumar P, Todor H, Huang KC, Gross CA. PMID: 34634934; PMCID: PMC8510551.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    7. AusTraits, a curated plant trait database for the Australian flora. Sci Data. 2021 09 30; 8(1):254. Falster D, Gallagher R, Wenk EH, Wright IJ, Indiarto D, Andrew SC, Baxter C, Lawson J, Allen S, Fuchs A, Monro A, Kar F, Adams MA, Ahrens CW, Alfonzetti M, Angevin T, Apgaua DMG, Arndt S, Atkin OK, Atkinson J, Auld T, Baker A, von Balthazar M, Bean A, Blackman CJ, Bloomfield K, Bowman DMJS, Bragg J, Brodribb TJ, Buckton G, Burrows G, Caldwell E, Camac J, Carpenter R, Catford JA, Cawthray GR, Cernusak LA, Chandler G, Chapman AR, Cheal D, Cheesman AW, Chen SC, Choat B, Clinton B, Clode PL, Coleman H, Cornwell WK, Cosgrove M, Crisp M, Cross E, Crous KY, Cunningham S, Curran T, Curtis E, Daws MI, DeGabriel JL, Denton MD, Dong N, Du P, Duan H, Duncan DH, Duncan RP, Duretto M, Dwyer JM, Edwards C, Esperon-Rodriguez M, Evans JR, Everingham SE, Farrell C, Firn J, Fonseca CR, French BJ, Frood D, Funk JL, Geange SR, Ghannoum O, Gleason SM, Gosper CR, Gray E, Groom PK, Grootemaat S, Gross C, Guerin G, Guja L, Hahs AK, Harrison MT, Hayes PE, Henery M, Hochuli D, Howell J, Huang G, Hughes L, Huisman J, Ilic J, Jagdish A, Jin D, Jordan G, Jurado E, Kanowski J, Kasel S, Kellermann J, Kenny B, Kohout M, Kooyman RM, Kotowska MM, Lai HR, Laliberté E, Lambers H, Lamont BB, Lanfear R, van Langevelde F, Laughlin DC, Laugier-Kitchener BA, Laurance S, Lehmann CER, Leigh A, Leishman MR, Lenz T, Lepschi B, Lewis JD, Lim F, Liu U, Lord J, Lusk CH, Macinnis-Ng C, McPherson H, Magallón S, Manea A, López-Martinez A, Mayfield M, McCarthy JK, Meers T, van der Merwe M, Metcalfe DJ, Milberg P, Mokany K, Moles AT, Moore BD, Moore N, Morgan JW, Morris W, Muir A, Munroe S, Nicholson Á, Nicolle D, Nicotra AB, Niinemets Ü, North T, O'Reilly-Nugent A, O'Sullivan OS, Oberle B, Onoda Y, Ooi MKJ, Osborne CP, Paczkowska G, Pekin B, Guilherme Pereira C, Pickering C, Pickup M, Pollock LJ, Poot P, Powell JR, Power SA, Prentice IC, Prior L, Prober SM, Read J, Reynolds V, Richards AE, Richardson B, Roderick ML, Rosell JA, Rossetto M, Rye B, Rymer PD, Sams MA, Sanson G, Sauquet H, Schmidt S, Schönenberger J, Schulze ED, Sendall K, Sinclair S, Smith B, Smith R, Soper F, Sparrow B, Standish RJ, Staples TL, Stephens R, Szota C, Taseski G, Tasker E, Thomas F, Tissue DT, Tjoelker MG, Tng DYP, de Tombeur F, Tomlinson K, Turner NC, Veneklaas EJ, Venn S, Vesk P, Vlasveld C, Vorontsova MS, Warren CA, Warwick N, Weerasinghe LK, Wells J, Westoby M, White M, Williams NSG, Wills J, Wilson PG, Yates C, Zanne AE, Zemunik G, Zieminska K. PMID: 34593819; PMCID: PMC8484355.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    8. Cold Shock Response in Bacteria. Annu Rev Genet. 2021 11 23; 55:377-400. Zhang Y, Gross CA. PMID: 34530639.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    9. Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. Mol Cell. 2021 05 20; 81(10):2201-2215.e9. Shiver AL, Osadnik H, Peters JM, Mooney RA, Wu PI, Henry KK, Braberg H, Krogan NJ, Hu JC, Landick R, Huang KC, Gross CA. PMID: 34019789; PMCID: PMC8484514.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    10. Computational pipeline for designing guide RNAs for mismatch-CRISPRi. STAR Protoc. 2021 Jun 18; 2(2):100521. van Gestel J, Hawkins JS, Todor H, Gross CA. PMID: 34027480; PMCID: PMC8121773.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    11. Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family. Nucleic Acids Res. 2021 01 25; 49(2):986-1005. Casas-Pastor D, Müller RR, Jaenicke S, Brinkrolf K, Becker A, Buttner MJ, Gross CA, Mascher T, Goesmann A, Fritz G. PMID: 33398323; PMCID: PMC7826278.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    12. Rewiring the specificity of extracytoplasmic function sigma factors. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):33496-33506. Todor H, Osadnik H, Campbell EA, Myers KS, Li H, Donohue TJ, Gross CA. PMID: 33318184; PMCID: PMC7776599.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    13. Genetic interaction mapping informs integrative structure determination of protein complexes. Science. 2020 12 11; 370(6522). Braberg H, Echeverria I, Bohn S, Cimermancic P, Shiver A, Alexander R, Xu J, Shales M, Dronamraju R, Jiang S, Dwivedi G, Bogdanoff D, Chaung KK, Hüttenhain R, Wang S, Mavor D, Pellarin R, Schneidman D, Bader JS, Fraser JS, Morris J, Haber JE, Strahl BD, Gross CA, Dai J, Boeke JD, Sali A, Krogan NJ. PMID: 33303586; PMCID: PMC7946025.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    14. Bacterial CRISPR screens for gene function. Curr Opin Microbiol. 2021 02; 59:102-109. Todor H, Silvis MR, Osadnik H, Gross CA. PMID: 33285498; PMCID: PMC8331264.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    15. Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis. Cell Syst. 2020 11 18; 11(5):523-535.e9. Hawkins JS, Silvis MR, Koo BM, Peters JM, Osadnik H, Jost M, Hearne CC, Weissman JS, Todor H, Gross CA. PMID: 33080209; PMCID: PMC7704046.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    16. Resistance to serine in Bacillus subtilis: identification of the serine transporter YbeC and of a metabolic network that links serine and threonine metabolism. Environ Microbiol. 2020 09; 22(9):3937-3949. Klewing A, Koo BM, Krüger L, Poehlein A, Reuß D, Daniel R, Gross CA, Stülke J. PMID: 32743959; PMCID: PMC8226366.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    17. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. Nat Biotechnol. 2020 Mar; 38(3):355-364. Jost M, Santos DA, Saunders RA, Horlbeck MA, Hawkins JS, Scaria SM, Norman TM, Hussmann JA, Liem CR, Gross CA, Weissman JS. PMID: 31932729; PMCID: PMC7065968.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    18. Discovery of the extracytoplasmic function σ factors. Mol Microbiol. 2019 08; 112(2):348-355. Lonetto MA, Donohue TJ, Gross CA, Buttner MJ. PMID: 31115926; PMCID: PMC8384415.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    19. Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis. Nucleic Acids Res. 2019 06 04; 47(10):5231-5242. Reuß DR, Faßhauer P, Mroch PJ, Ul-Haq I, Koo BM, Pöhlein A, Gross CA, Daniel R, Brantl S, Stülke J. PMID: 30957856; PMCID: PMC6547408.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    20. Modeling of Protein Complex Architectures using Combinatorial Genetic Perturbations. Biophysical Journal. 2019 Feb 1; 116(3):419a-420a. Echeverria EI, Braberg BH, Cimermancic CP, Pellarin PR, Schneidman SD, Shiver SA, Gross GC, Krogan KN, Sali SA. .
      View in: Publisher Site   Mentions:
    21. Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi. Nat Microbiol. 2019 02; 4(2):244-250. Peters JM, Koo BM, Patino R, Heussler GE, Hearne CC, Qu J, Inclan YF, Hawkins JS, Lu CHS, Silvis MR, Harden MM, Osadnik H, Peters JE, Engel JN, Dutton RJ, Grossman AD, Gross CA, Rosenberg OS. PMID: 30617347; PMCID: PMC6424567.
      View in: PubMed   Mentions: 83     Fields:    Translation:Cells
    22. Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus. J Am Chem Soc. 2018 06 20; 140(24):7471-7485. Bhate MP, Lemmin T, Kuenze G, Mensa B, Ganguly S, Peters JM, Schmidt N, Pelton JG, Gross CA, Meiler J, DeGrado WF. PMID: 29771498; PMCID: PMC6499544.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    23. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Mol Cell. 2018 04 19; 70(2):274-286.e7. Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. PMID: 29628307; PMCID: PMC5910227.
      View in: PubMed   Mentions: 71     Fields:    Translation:Cells
    24. Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile. ACS Infect Dis. 2018 01 12; 4(1):59-67. Ochoa JL, Sanchez LM, Koo BM, Doherty JS, Rajendram M, Huang KC, Gross CA, Linington RG. PMID: 29043783; PMCID: PMC6530793.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    25. Ribosomal Architecture: Constraints Imposed by the Need for Self-Production. Curr Biol. 2017 08 21; 27(16):R798-R800. Hussmann JA, Osadnik H, Gross CA. PMID: 28829964.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    26. Global analysis of translation termination in E. coli. PLoS Genet. 2017 03; 13(3):e1006676. Baggett NE, Zhang Y, Gross CA. PMID: 28301469; PMCID: PMC5373646.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    27. Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis. Cell Syst. 2017 03 22; 4(3):291-305.e7. Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA. PMID: 28189581; PMCID: PMC5400513.
      View in: PubMed   Mentions: 258     Fields:    Translation:Cells
    28. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 2017 01 31; 6. Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. PMID: 28139975; PMCID: PMC5318159.
      View in: PubMed   Mentions: 74     Fields:    Translation:Cells
    29. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. PMID: 27984733; PMCID: PMC5315571.
      View in: PubMed   Mentions: 436     Fields:    Translation:HumansAnimalsCells
    30. Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. J Biol Chem. 2016 Dec 09; 291(50):26066-26082. Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED. PMID: 27780866; PMCID: PMC5207077.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    31. Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis. J Bacteriol. 2016 11 01; 198(21):2925-2935. Zhao H, Sun Y, Peters JM, Gross CA, Garner EC, Helmann JD. PMID: 27528508; PMCID: PMC5055597.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    32. A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S. PLoS Genet. 2016 06; 12(6):e1006124. Shiver AL, Osadnik H, Kritikos G, Li B, Krogan N, Typas A, Gross CA. PMID: 27355376; PMCID: PMC4927156.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    33. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. 2016 Jun 02; 165(6):1493-1506. Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA. PMID: 27238023; PMCID: PMC4894308.
      View in: PubMed   Mentions: 290     Fields:    Translation:Cells
    34. DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):E6862-71. Parshin A, Shiver AL, Lee J, Ozerova M, Schneidman-Duhovny D, Gross CA, Borukhov S. PMID: 26604313; PMCID: PMC4687573.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    35. Bacterial CRISPR: accomplishments and prospects. Curr Opin Microbiol. 2015 Oct; 27:121-6. Peters JM, Silvis MR, Zhao D, Hawkins JS, Gross CA, Qi LS. PMID: 26363124; PMCID: PMC4659716.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    36. High-throughput bacterial functional genomics in the sequencing era. Curr Opin Microbiol. 2015 Oct; 27:86-95. Gray AN, Koo BM, Shiver AL, Peters JM, Osadnik H, Gross CA. PMID: 26336012; PMCID: PMC4659725.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    37. Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division. Elife. 2015 May 07; 4. Gray AN, Egan AJ, Van't Veer IL, Verheul J, Colavin A, Koumoutsi A, Biboy J, Altelaar AF, Damen MJ, Huang KC, Simorre JP, Breukink E, den Blaauwen T, Typas A, Gross CA, Vollmer W. PMID: 25951518; PMCID: PMC4458516.
      View in: PubMed   Mentions: 100     Fields:    Translation:Cells
    38. MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6437-42. Meeske AJ, Sham LT, Kimsey H, Koo BM, Gross CA, Bernhardt TG, Rudner DZ. PMID: 25918422; PMCID: PMC4443310.
      View in: PubMed   Mentions: 99     Fields:    Translation:Cells
    39. Editorial overview: Cell regulation: when you think you know it all, there is another layer to be discovered. Curr Opin Microbiol. 2015 Apr; 24:v-vii. Gross CA, Gründling A. PMID: 25708065.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    40. MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein. Genes Dev. 2014 Jul 15; 28(14):1620-34. Guo MS, Updegrove TB, Gogol EB, Shabalina SA, Gross CA, Storz G. PMID: 25030700; PMCID: PMC4102768.
      View in: PubMed   Mentions: 132     Fields:    Translation:Cells
    41. Bacterial sigma factors: a historical, structural, and genomic perspective. Annu Rev Microbiol. 2014; 68:357-76. Feklístov A, Sharon BD, Darst SA, Gross CA. PMID: 25002089.
      View in: PubMed   Mentions: 251     Fields:    Translation:Cells
    42. Stress-induced remodeling of the bacterial proteome. Curr Biol. 2014 May 19; 24(10):R424-34. Guo MS, Gross CA. PMID: 24845675; PMCID: PMC4089988.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    43. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science. 2014 May 30; 344(6187):1042-7. Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. PMID: 24789973; PMCID: PMC4108260.
      View in: PubMed   Mentions: 172     Fields:    Translation:Cells
    44. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 2014 Apr 24; 157(3):624-35. Li GW, Burkhardt D, Gross C, Weissman JS. PMID: 24766808; PMCID: PMC4006352.
      View in: PubMed   Mentions: 631     Fields:    Translation:AnimalsCells
    45. Promoter melting by an alternative σ, one base at a time. Nat Struct Mol Biol. 2014 Apr; 21(4):350-1. Darst SA, Feklistov A, Gross CA. PMID: 24699085; PMCID: PMC5433862.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    46. Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol. 2013 Dec; 11(12):e1001735. Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA. PMID: 24358019; PMCID: PMC3866087.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    47. Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters. Mol Syst Biol. 2013 Oct 29; 9:702. Rhodius VA, Segall-Shapiro TH, Sharon BD, Ghodasara A, Orlova E, Tabakh H, Burkhardt DH, Clancy K, Peterson TC, Gross CA, Voigt CA. PMID: 24169405; PMCID: PMC3817407.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    48. Dual molecular signals mediate the bacterial response to outer-membrane stress. Science. 2013 May 17; 340(6134):837-41. Lima S, Guo MS, Chaba R, Gross CA, Sauer RT. PMID: 23687042; PMCID: PMC3928677.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    49. Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. J Am Chem Soc. 2012 Oct 31; 134(43):18074-81. McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. PMID: 23088750; PMCID: PMC3499099.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    50. The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA. Protein Sci. 2012 Sep; 21(9):1334-43. Kwon E, Kim DY, Ngo TD, Gross CA, Gross JD, Kim KK. PMID: 22760860; PMCID: PMC3631362.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    51. From the regulation of peptidoglycan synthesis to bacterial growth and morphology. Nat Rev Microbiol. 2011 Dec 28; 10(2):123-36. Typas A, Banzhaf M, Gross CA, Vollmer W. PMID: 22203377; PMCID: PMC5433867.
      View in: PubMed   Mentions: 588     Fields:    Translation:Cells
    52. Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo. Cell. 2011 Dec 09; 147(6):1295-308. Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B. PMID: 22153074; PMCID: PMC3277850.
      View in: PubMed   Mentions: 233     Fields:    Translation:Cells
    53. Predicting the strength of UP-elements and full-length E. coli σE promoters. Nucleic Acids Res. 2012 Apr; 40(7):2907-24. Rhodius VA, Mutalik VK, Gross CA. PMID: 22156164; PMCID: PMC3326320.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    54. Unexpected stress-reducing effect of PhaP, a poly(3-hydroxybutyrate) granule-associated protein, in Escherichia coli. Appl Environ Microbiol. 2011 Sep; 77(18):6622-9. de Almeida A, Catone MV, Rhodius VA, Gross CA, Pettinari MJ. PMID: 21784905; PMCID: PMC3187130.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    55. Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12875-80. Gogol EB, Rhodius VA, Papenfort K, Vogel J, Gross CA. PMID: 21768388; PMCID: PMC3150882.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
    56. Signal integration by DegS and RseB governs the σ E-mediated envelope stress response in Escherichia coli. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):2106-11. Chaba R, Alba BM, Guo MS, Sohn J, Ahuja N, Sauer RT, Gross CA. PMID: 21245315; PMCID: PMC3033255.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    57. Using DNA microarrays to assay part function. Methods Enzymol. 2011; 497:75-113. Rhodius VA, Gross CA. PMID: 21601083; PMCID: PMC5433866.
      View in: PubMed   Mentions: 6     Fields:    
    58. Phenotypic landscape of a bacterial cell. Cell. 2011 Jan 07; 144(1):143-56. Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak KM, Lee KJ, Wong A, Shales M, Lovett S, Winkler ME, Krogan NJ, Typas A, Gross CA. PMID: 21185072; PMCID: PMC3060659.
      View in: PubMed   Mentions: 370     Fields:    Translation:Cells
    59. Regulation of peptidoglycan synthesis by outer-membrane proteins. Cell. 2010 Dec 23; 143(7):1097-109. Typas A, Banzhaf M, van den Berg van Saparoea B, Verheul J, Biboy J, Nichols RJ, Zietek M, Beilharz K, Kannenberg K, von Rechenberg M, Breukink E, den Blaauwen T, Gross CA, Vollmer W. PMID: 21183073; PMCID: PMC3060616.
      View in: PubMed   Mentions: 198     Fields:    Translation:Cells
    60. Cellular Response to Heat Shock and Cold Shock. . 2010 Nov 16; 91-114. Lim LB, Gross GC. .
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    61. The crystal structure Escherichia coli Spy. Protein Sci. 2010 Nov; 19(11):2252-9. Kwon E, Kim DY, Gross CA, Gross JD, Kim KK. PMID: 20799348; PMCID: PMC3005795.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    62. Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition. Genes Dev. 2009 Oct 15; 23(20):2426-36. Koo BM, Rhodius VA, Nonaka G, deHaseth PL, Gross CA. PMID: 19833768; PMCID: PMC2764494.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    63. Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica. J Bacteriol. 2009 Dec; 191(23):7279-87. Mutalik VK, Nonaka G, Ades SE, Rhodius VA, Gross CA. PMID: 19783623; PMCID: PMC2786571.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    64. Mutational analysis of Escherichia coli sigma28 and its target promoters reveals recognition of a composite -10 region, comprised of an 'extended -10' motif and a core -10 element. Mol Microbiol. 2009 May; 72(4):830-43. Koo BM, Rhodius VA, Campbell EA, Gross CA. PMID: 19400790; PMCID: PMC2756079.
      View in: PubMed   Mentions: 18     Fields:    
    65. Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element. Mol Microbiol. 2009 May; 72(4):815-29. Koo BM, Rhodius VA, Campbell EA, Gross CA. PMID: 19400791; PMCID: PMC4412615.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    66. Analyzing the interaction of RseA and RseB, the two negative regulators of the sigmaE envelope stress response, using a combined bioinformatic and experimental strategy. J Biol Chem. 2009 Feb 20; 284(8):5403-13. Ahuja N, Korkin D, Chaba R, Cezairliyan BO, Sauer RT, Kim KK, Gross CA. PMID: 19103591; PMCID: PMC2643490.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    67. Convergence of molecular, modeling, and systems approaches for an understanding of the Escherichia coli heat shock response. Microbiol Mol Biol Rev. 2008 Sep; 72(3):545-54. Guisbert E, Yura T, Rhodius VA, Gross CA. PMID: 18772288; PMCID: PMC2546862.
      View in: PubMed   Mentions: 112     Fields:    Translation:Cells
    68. High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods. 2008 Sep; 5(9):781-7. Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. PMID: 19160513; PMCID: PMC2700713.
      View in: PubMed   Mentions: 133     Fields:    Translation:Cells
    69. An extra-cytoplasmic function sigma factor and anti-sigma factor control carotenoid biosynthesis in Azospirillum brasilense. Microbiology (Reading). 2008 Jul; 154(Pt 7):2096-2105. Thirunavukkarasu N, Mishra MN, Spaepen S, Vanderleyden J, Gross CA, Tripathi AK. PMID: 18599837.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    70. Analysis of sigma32 mutants defective in chaperone-mediated feedback control reveals unexpected complexity of the heat shock response. Proc Natl Acad Sci U S A. 2007 Nov 06; 104(45):17638-43. Yura T, Guisbert E, Poritz M, Lu CZ, Campbell E, Gross CA. PMID: 17968012; PMCID: PMC2077055.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    71. Design principles of the proteolytic cascade governing the sigmaE-mediated envelope stress response in Escherichia coli: keys to graded, buffered, and rapid signal transduction. Genes Dev. 2007 Jan 01; 21(1):124-36. Chaba R, Grigorova IL, Flynn JM, Baker TA, Gross CA. PMID: 17210793; PMCID: PMC1759897.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    72. Hfq modulates the sigmaE-mediated envelope stress response and the sigma32-mediated cytoplasmic stress response in Escherichia coli. J Bacteriol. 2007 Mar; 189(5):1963-73. Guisbert E, Rhodius VA, Ahuja N, Witkin E, Gross CA. PMID: 17158661; PMCID: PMC1855744.
      View in: PubMed   Mentions: 88     Fields:    Translation:Cells
    73. Regulation and Function of the Envelope Stress Response Controlled by sE. . 2006 Nov 22; 107-121. Gross GC, Rhodius RV, Grigorova GI. .
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    74. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Genes Dev. 2006 Jul 01; 20(13):1776-89. Nonaka G, Blankschien M, Herman C, Gross CA, Rhodius VA. PMID: 16818608; PMCID: PMC1522074.
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    75. Module-based analysis of robustness tradeoffs in the heat shock response system. PLoS Comput Biol. 2006 Jul 28; 2(7):e59. Kurata H, El-Samad H, Iwasaki R, Ohtake H, Doyle JC, Grigorova I, Gross CA, Khammash M. PMID: 16863396; PMCID: PMC1523291.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    76. Insights into transcriptional regulation and sigma competition from an equilibrium model of RNA polymerase binding to DNA. Proc Natl Acad Sci U S A. 2006 Apr 04; 103(14):5332-7. Grigorova IL, Phleger NJ, Mutalik VK, Gross CA. PMID: 16567622; PMCID: PMC1459355.
      View in: PubMed   Mentions: 98     Fields:    Translation:Cells
    77. Conserved and variable functions of the sigmaE stress response in related genomes. PLoS Biol. 2006 Jan; 4(1):e2. Rhodius VA, Suh WC, Nonaka G, West J, Gross CA. PMID: 16336047; PMCID: PMC1312014.
      View in: PubMed   Mentions: 300     Fields:    Translation:Cells
    78. Characterization of six lipoproteins in the sigmaE regulon. J Bacteriol. 2005 Jul; 187(13):4552-61. Onufryk C, Crouch ML, Fang FC, Gross CA. PMID: 15968066; PMCID: PMC1151791.
      View in: PubMed   Mentions: 81     Fields:    Translation:Cells
    79. An open letter to Elias Zerhouni. Science. 2005 Mar 04; 307(5714):1409-10. Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N. PMID: 15746409.
      View in: PubMed   Mentions: 3     Fields:    Translation:PHPublic Health
    80. Surviving heat shock: control strategies for robustness and performance. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2736-41. El-Samad H, Kurata H, Doyle JC, Gross CA, Khammash M. PMID: 15668395; PMCID: PMC549435.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    81. Altering the interaction between sigma70 and RNA polymerase generates complexes with distinct transcription-elongation properties. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):1157-62. Berghöfer-Hochheimer Y, Lu CZ, Gross CA. PMID: 15650048; PMCID: PMC545856.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    82. Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System. PLoS Computational Biology. 2005 Jan 1; preprint(2006):e59. Kurata KH, El-Samad EH, Iwasaki IR, Ohtake OH, Doyle DJ, Grigorova GI, Gross GC, Khammash KM. .
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    83. A chaperone network controls the heat shock response in E. coli. Genes Dev. 2004 Nov 15; 18(22):2812-21. Guisbert E, Herman C, Lu CZ, Gross CA. PMID: 15545634; PMCID: PMC528900.
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    84. Fine-tuning of the Escherichia coli sigmaE envelope stress response relies on multiple mechanisms to inhibit signal-independent proteolysis of the transmembrane anti-sigma factor, RseA. Genes Dev. 2004 Nov 01; 18(21):2686-97. Grigorova IL, Chaba R, Zhong HJ, Alba BM, Rhodius V, Herman C, Gross CA. PMID: 15520285; PMCID: PMC525548.
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    85. A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function. J Mol Biol. 2004 Oct 22; 343(3):569-87. Geszvain K, Gruber TM, Mooney RA, Gross CA, Landick R. PMID: 15465046.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    86. Regulation of the Escherichia coli sigma-dependent envelope stress response. Mol Microbiol. 2004 May; 52(3):613-9. Alba BM, Gross CA. PMID: 15101969.
      View in: PubMed   Mentions: 172     Fields:    Translation:AnimalsCells
    87. Minimal machinery of RNA polymerase holoenzyme sufficient for promoter melting. Science. 2004 Feb 27; 303(5662):1382-4. Young BA, Gruber TM, Gross CA. PMID: 14988563.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    88. Ira Herskowitz (1946–2003). Cell. 2003 Jul 1; 114(1):9-10. Stahl SF, Gross GC. .
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    89. OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain. Cell. 2003 Apr 04; 113(1):61-71. Walsh NP, Alba BM, Bose B, Gross CA, Sauer RT. PMID: 12679035.
      View in: PubMed   Mentions: 237     Fields:    Translation:Cells
    90. Regulation of the alternative sigma factor sigma(E) during initiation, adaptation, and shutoff of the extracytoplasmic heat shock response in Escherichia coli. J Bacteriol. 2003 Apr; 185(8):2512-9. Ades SE, Grigorova IL, Gross CA. PMID: 12670975; PMCID: PMC152616.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    91. Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol Cell. 2003 Apr; 11(4):1067-78. Campbell EA, Tupy JL, Gruber TM, Wang S, Sharp MM, Gross CA, Darst SA. PMID: 12718891.
      View in: PubMed   Mentions: 118     Fields:    Translation:Cells
    92. Cell regulation. Current Opinion in Microbiology. 2003 Apr 1; 6(2):91-92. Gross GC, Lazdunski LA. .
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    93. Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH. Mol Cell. 2003 Mar; 11(3):659-69. Herman C, Prakash S, Lu CZ, Matouschek A, Gross CA. PMID: 12667449.
      View in: PubMed   Mentions: 74     Fields:    Translation:Cells
    94. Multiple sigma subunits and the partitioning of bacterial transcription space. Annu Rev Microbiol. 2003; 57:441-66. Gruber TM, Gross CA. PMID: 14527287.
      View in: PubMed   Mentions: 429     Fields:    Translation:Cells
    95. Assay of Escherichia coli RNA polymerase: sigma-core interactions. Methods Enzymol. 2003; 370:206-12. Gruber TM, Gross CA. PMID: 14712646.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    96. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 2002 Dec 27; 111(7):1027-39. Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. PMID: 12507429.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    97. DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response. Genes Dev. 2002 Aug 15; 16(16):2156-68. Alba BM, Leeds JA, Onufryk C, Lu CZ, Gross CA. PMID: 12183369; PMCID: PMC186436.
      View in: PubMed   Mentions: 160     Fields:    Translation:Cells
    98. Identification of the binding sites of regulatory proteins in bacterial genomes. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11772-7. Li H, Rhodius V, Gross C, Siggia ED. PMID: 12181488; PMCID: PMC129344.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    99. Views of transcription initiation. Cell. 2002 May 17; 109(4):417-20. Young BA, Gruber TM, Gross CA. PMID: 12086598.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    100. Impact of genomic technologies on studies of bacterial gene expression. Annu Rev Microbiol. 2002; 56:599-624. Rhodius V, Van Dyk TK, Gross C, LaRossa RA. PMID: 12142487.
      View in: PubMed   Mentions: 12     Fields:    
    101. The anti-initial transcribed sequence, a portable sequence that impedes promoter escape, requires sigma70 for function. J Biol Chem. 2001 Oct 12; 276(41):38201-9. Chan CL, Gross CA. PMID: 11481327.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    102. Binding of the initiation factor sigma(70) to core RNA polymerase is a multistep process. Mol Cell. 2001 Jul; 8(1):21-31. Gruber TM, Markov D, Sharp MM, Young BA, Lu CZ, Zhong HJ, Artsimovitch I, Geszvain KM, Arthur TM, Burgess RR, Landick R, Severinov K, Gross CA. PMID: 11511357.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    103. A coiled-coil from the RNA polymerase beta' subunit allosterically induces selective nontemplate strand binding by sigma(70). Cell. 2001 Jun 29; 105(7):935-44. Young BA, Anthony LC, Gruber TM, Arthur TM, Heyduk E, Lu CZ, Sharp MM, Heyduk T, Burgess RR, Gross CA. PMID: 11439189.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    104. degS (hhoB) is an essential Escherichia coli gene whose indispensable function is to provide sigma (E) activity. Mol Microbiol. 2001 Jun; 40(6):1323-33. Alba BM, Zhong HJ, Pelayo JC, Gross CA. PMID: 11442831.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    105. Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations. J Bacteriol. 2001 Apr; 183(7):2289-97. Cicero MP, Sharp MM, Gross CA, Kreuzer KN. PMID: 11244069; PMCID: PMC95136.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    106. The 2000 Thomas Hunt Morgan Medal. Evelyn M. Witkin. Genetics. 2001 Feb; 157(2):459-61. Gross CA. PMID: 11370620; PMCID: PMC1461505.
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    107. The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity. EMBO J. 2001 Jan 15; 20(1-2):285-94. Behrens S, Maier R, de Cock H, Schmid FX, Gross CA. PMID: 11226178; PMCID: PMC140197.
      View in: PubMed   Mentions: 87     Fields:    Translation:Cells
    108. The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized. Genes Dev. 1999 Nov 15; 13(22):3015-26. Sharp MM, Chan CL, Lu CZ, Marr MT, Nechaev S, Merritt EW, Severinov K, Roberts JW, Gross CA. PMID: 10580008; PMCID: PMC317155.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    109. Structural features required for the interaction of the Hsp70 molecular chaperone DnaK with its cochaperone DnaJ. J Biol Chem. 1999 Oct 22; 274(43):30534-9. Suh WC, Lu CZ, Gross CA. PMID: 10521435.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    110. The Escherichia coli sigma(E)-dependent extracytoplasmic stress response is controlled by the regulated proteolysis of an anti-sigma factor. Genes Dev. 1999 Sep 15; 13(18):2449-61. Ades SE, Connolly LE, Alba BM, Gross CA. PMID: 10500101; PMCID: PMC317020.
      View in: PubMed   Mentions: 115     Fields:    Translation:Cells
    111. Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15223-8. Suh WC, Burkholder WF, Lu CZ, Zhao X, Gottesman ME, Gross CA. PMID: 9860950; PMCID: PMC28024.
      View in: PubMed   Mentions: 114     Fields:    Translation:Cells
    112. The functional and regulatory roles of sigma factors in transcription. Cold Spring Harb Symp Quant Biol. 1998; 63:141-55. Gross CA, Chan C, Dombroski A, Gruber T, Sharp M, Tupy J, Young B. PMID: 10384278.
      View in: PubMed   Mentions: 138     Fields:    Translation:Cells
    113. SigmaE is an essential sigma factor in Escherichia coli. J Bacteriol. 1997 Nov; 179(21):6862-4. De Las Peñas A, Connolly L, Gross CA. PMID: 9352942; PMCID: PMC179621.
      View in: PubMed   Mentions: 106     Fields:    Translation:Cells
    114. The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways. Genes Dev. 1997 Aug 01; 11(15):2012-21. Connolly L, De Las Penas A, Alba BM, Gross CA. PMID: 9271123; PMCID: PMC316410.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    115. The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. Mol Microbiol. 1997 Apr; 24(2):373-85. De Las Peñas A, Connolly L, Gross CA. PMID: 9159523.
      View in: PubMed   Mentions: 140     Fields:    Translation:Cells
    116. SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins. Genes Dev. 1996 Dec 15; 10(24):3170-82. Rouvière PE, Gross CA. PMID: 8985185.
      View in: PubMed   Mentions: 131     Fields:    Translation:Cells
    117. Sigma domain structure: one down, one to go. Structure. 1996 Nov 15; 4(11):1235-8. Chan CL, Lonetto MA, Gross CA. PMID: 8939761.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    118. Isolation, purification, and in vitro characterization of recessive-lethal-mutant RNA polymerases from Escherichia coli. J Bacteriol. 1996 Sep; 178(17):5263-71. Tavormina PL, Landick R, Gross CA. PMID: 8752347; PMCID: PMC178326.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    119. The sigma subunit of Escherichia coli RNA polymerase senses promoter spacing. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):8858-62. Dombroski AJ, Johnson BD, Lonetto M, Gross CA. PMID: 8799117; PMCID: PMC38558.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    120. Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex. J Biol Chem. 1996 Jun 14; 271(24):14572-83. Heisler LM, Feng G, Jin DJ, Gross CA, Landick R. PMID: 8662850.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    121. Involvement of the DnaK-DnaJ-GrpE chaperone team in protein secretion in Escherichia coli. J Bacteriol. 1996 Jun; 178(12):3608-13. Wild J, Rossmeissl P, Walter WA, Gross CA. PMID: 8655561; PMCID: PMC178133.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    122. Identifying interacting regions in the beta subunit of Escherichia coli RNA polymerase. J Mol Biol. 1996 May 03; 258(2):213-23. Tavormina PL, Reznikoff WS, Gross CA. PMID: 8627620.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    123. A structure/function analysis of Escherichia coli RNA polymerase. Philos Trans R Soc Lond B Biol Sci. 1996 Apr 29; 351(1339):475-82. Gross CA, Chan CL, Lonetto MA. PMID: 8735269.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    124. Analysis of three DnaK mutant proteins suggests that progression through the ATPase cycle requires conformational changes. J Biol Chem. 1995 Dec 15; 270(50):30051-9. Kamath-Loeb AS, Lu CZ, Suh WC, Lonetto MA, Gross CA. PMID: 8530409.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    125. rpoE, the gene encoding the second heat-shock sigma factor, sigma E, in Escherichia coli. EMBO J. 1995 Mar 01; 14(5):1032-42. Rouvière PE, De Las Peñas A, Mecsas J, Lu CZ, Rudd KE, Gross CA. PMID: 7889934; PMCID: PMC398175.
      View in: PubMed   Mentions: 136     Fields:    Translation:Cells
    126. Identification and characterization of an outer membrane protein, OmpX, in Escherichia coli that is homologous to a family of outer membrane proteins including Ail of Yersinia enterocolitica. J Bacteriol. 1995 Feb; 177(3):799-804. Mecsas J, Welch R, Erickson JW, Gross CA. PMID: 7836315; PMCID: PMC176659.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    127. Four contiguous amino acids define the target for streptolydigin resistance in the beta subunit of Escherichia coli RNA polymerase. J Biol Chem. 1993 Dec 05; 268(34):25369-75. Heisler LM, Suzuki H, Landick R, Gross CA. PMID: 8244969.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    128. Amino-terminal amino acids modulate sigma-factor DNA-binding activity. Genes Dev. 1993 Dec; 7(12A):2446-55. Dombroski AJ, Walter WA, Gross CA. PMID: 8253389.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    129. The activity of sigma E, an Escherichia coli heat-inducible sigma-factor, is modulated by expression of outer membrane proteins. Genes Dev. 1993 Dec; 7(12B):2618-28. Mecsas J, Rouviere PE, Erickson JW, Donohue TJ, Gross CA. PMID: 8276244.
      View in: PubMed   Mentions: 198     Fields:    Translation:Cells
    130. Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response. J Bacteriol. 1993 Jul; 175(13):3992-7. Wild J, Walter WA, Gross CA, Altman E. PMID: 8320215; PMCID: PMC204827.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    131. The role of the sigma subunit in promoter recognition by RNA polymerase. Cell Mol Biol Res. 1993; 39(4):311-7. Dombroski AJ, Walter WA, Gross CA. PMID: 8312965.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    132. How a mutation in the gene encoding sigma 70 suppresses the defective heat shock response caused by a mutation in the gene encoding sigma 32. J Bacteriol. 1992 Nov; 174(22):7128-37. Zhou YN, Gross CA. PMID: 1385385; PMCID: PMC207402.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    133. DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli. J Bacteriol. 1992 Oct; 174(19):6256-63. Shi W, Zhou Y, Wild J, Adler J, Gross CA. PMID: 1400176; PMCID: PMC207695.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    134. Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA. Cell. 1992 Aug 07; 70(3):501-12. Dombroski AJ, Walter WA, Record MT, Siegele DA, Gross CA. PMID: 1643661.
      View in: PubMed   Mentions: 112     Fields:    Translation:Cells
    135. A mutant sigma 32 with a small deletion in conserved region 3 of sigma has reduced affinity for core RNA polymerase. J Bacteriol. 1992 Aug; 174(15):5005-12. Zhou YN, Walter WA, Gross CA. PMID: 1629156; PMCID: PMC206314.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    136. Partial loss of function mutations in DnaK, the Escherichia coli homologue of the 70-kDa heat shock proteins, affect highly conserved amino acids implicated in ATP binding and hydrolysis. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7139-43. Wild J, Kamath-Loeb A, Ziegelhoffer E, Lonetto M, Kawasaki Y, Gross CA. PMID: 1386674; PMCID: PMC49661.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    137. DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli. Genes Dev. 1992 Jul; 6(7):1165-72. Wild J, Altman E, Yura T, Gross CA. PMID: 1628824.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    138. The sigma 70 family: sequence conservation and evolutionary relationships. J Bacteriol. 1992 Jun; 174(12):3843-9. Lonetto M, Gribskov M, Gross CA. PMID: 1597408; PMCID: PMC206090.
      View in: PubMed   Mentions: 359     Fields:    Translation:Cells
    139. Physiological effects of the fructose-1,6-diphosphate aldolase ts8 mutation on stable RNA synthesis in Escherichia coli. J Bacteriol. 1991 Oct; 173(19):6249-57. Singer M, Walter WA, Cali BM, Rouviere P, Liebke HH, Gourse RL, Gross CA. PMID: 1717436; PMCID: PMC208377.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    140. RpoB8, a rifampicin-resistant termination-proficient RNA polymerase, has an increased Km for purine nucleotides during transcription elongation. J Biol Chem. 1991 Aug 05; 266(22):14478-85. Jin DJ, Gross CA. PMID: 1860856.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    141. Development of RNA polymerase-promoter contacts during open complex formation. J Mol Biol. 1991 Aug 05; 220(3):585-97. Mecsas J, Cowing DW, Gross CA. PMID: 1651395.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    142. Translational regulation of sigma 32 synthesis: requirement for an internal control element. J Bacteriol. 1991 Jun; 173(12):3904-6. Kamath-Loeb AS, Gross CA. PMID: 2050641; PMCID: PMC208024.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    143. DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32. Genes Dev. 1990 Dec; 4(12A):2202-9. Straus D, Walter W, Gross CA. PMID: 2269429.
      View in: PubMed   Mentions: 158     Fields:    Translation:Cells
    144. Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter. J Mol Biol. 1989 Dec 05; 210(3):521-30. Cowing DW, Mecsas J, Record MT, Gross CA. PMID: 2693737.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    145. Interaction of Escherichia coli RNA polymerase holoenzyme containing sigma 32 with heat shock promoters. DNase I footprinting and methylation protection. J Mol Biol. 1989 Dec 05; 210(3):513-20. Cowing DW, Gross CA. PMID: 2693736.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    146. The activity of sigma 32 is reduced under conditions of excess heat shock protein production in Escherichia coli. Genes Dev. 1989 Dec; 3(12A):2003-10. Straus DB, Walter WA, Gross CA. PMID: 2695391.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    147. Identification of the sigma E subunit of Escherichia coli RNA polymerase: a second alternate sigma factor involved in high-temperature gene expression. Genes Dev. 1989 Sep; 3(9):1462-71. Erickson JW, Gross CA. PMID: 2691330.
      View in: PubMed   Mentions: 187     Fields:    Translation:Cells
    148. Altered promoter recognition by mutant forms of the sigma 70 subunit of Escherichia coli RNA polymerase. J Mol Biol. 1989 Apr 20; 206(4):591-603. Siegele DA, Hu JC, Walter WA, Gross CA. PMID: 2661828.
      View in: PubMed   Mentions: 147     Fields:    Translation:Cells
    149. A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli. Microbiol Rev. 1989 Mar; 53(1):1-24. Singer M, Baker TA, Schnitzler G, Deischel SM, Goel M, Dove W, Jaacks KJ, Grossman AD, Erickson JW, Gross CA. PMID: 2540407; PMCID: PMC372715.
      View in: PubMed   Mentions: 443     Fields:    Translation:Cells
    150. A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli. Microbiology and Molecular Biology Reviews. 1989 Jan 1; 53(1):1-24. Singer SM, Baker BT, Schnitzler SG, Deischel DS, Goel GM, Dove DW, Jaacks JK, Grossman GA, Erickson EJ, Gross GC. .
      View in: Publisher Site   Mentions:
    151. Escherichia coli heat shock gene mutants are defective in proteolysis. Genes Dev. 1988 Dec; 2(12B):1851-8. Straus DB, Walter WA, Gross CA. PMID: 3149251.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    152. Mutations in rpoD that increase expression of genes in the mal regulon of Escherichia coli K-12. J Mol Biol. 1988 Sep 05; 203(1):15-27. Hu JC, Gross CA. PMID: 3054119.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    153. Mutations in rpoD, the gene encoding the sigma 70 subunit of Escherichia coli RNA polymerase, that increase expression of the lac operon in the absence of CAP-cAMP. J Mol Biol. 1988 Sep 05; 203(1):29-37. Siegele DA, Hu JC, Gross CA. PMID: 2846853.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    154. Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32. J Bacteriol. 1988 Aug; 170(8):3640-9. Zhou YN, Kusukawa N, Erickson JW, Gross CA, Yura T. PMID: 2900239; PMCID: PMC211339.
      View in: PubMed   Mentions: 109     Fields:    Translation:Cells
    155. The heat shock response of E. coli is regulated by changes in the concentration of sigma 32. Nature. 1987 Sep 24-30; 329(6137):348-51. Straus DB, Walter WA, Gross CA. PMID: 3306410.
      View in: PubMed   Mentions: 181     Fields:    Translation:Cells
    156. Regulation of the promoters and transcripts of rpoH, the Escherichia coli heat shock regulatory gene. Genes Dev. 1987 Jul; 1(5):419-32. Erickson JW, Vaughn V, Walter WA, Neidhardt FC, Gross CA. PMID: 3315851.
      View in: PubMed   Mentions: 84     Fields:    Translation:Cells
    157. Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli. Genes Dev. 1987 Apr; 1(2):179-84. Grossman AD, Straus DB, Walter WA, Gross CA. PMID: 3315848.
      View in: PubMed   Mentions: 110     Fields:    Translation:Cells
    158. Regulation of the Heat-Shock Response in Escherichia coli. New Frontiers in the Study of Gene Functions. 1987 Jan 1; 21-32. Gross GC, Cowing CD, Erickson EJ, Grossman GA, Straus SD, Walter WW, Zhou ZY. .
      View in: Publisher Site   Mentions:
    159. Stringent response in Escherichia coli induces expression of heat shock proteins. J Mol Biol. 1985 Nov 20; 186(2):357-65. Grossman AD, Taylor WE, Burton ZF, Burgess RR, Gross CA. PMID: 3910841.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    160. Consensus sequence for Escherichia coli heat shock gene promoters. Proc Natl Acad Sci U S A. 1985 May; 82(9):2679-83. Cowing DW, Bardwell JC, Craig EA, Woolford C, Hendrix RW, Gross CA. PMID: 3887408; PMCID: PMC397628.
      View in: PubMed   Mentions: 168     Fields:    Translation:Cells
    161. The regulation of transcription initiation in bacteria. Annu Rev Genet. 1985; 19:355-87. Reznikoff WS, Siegele DA, Cowing DW, Gross CA. PMID: 3936407.
      View in: PubMed   Mentions: 112     Fields:    Translation:Cells
    162. Mutations in the sigma subunit of E. coli RNA polymerase which affect positive control of transcription. Mol Gen Genet. 1985; 199(1):7-13. Hu JC, Gross CA. PMID: 3889551.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    163. A gene regulating the heat shock response in Escherichia coli also affects proteolysis. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6779-83. Baker TA, Grossman AD, Gross CA. PMID: 6387713; PMCID: PMC392015.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    164. The htpR gene product of E. coli is a sigma factor for heat-shock promoters. Cell. 1984 Sep; 38(2):383-90. Grossman AD, Erickson JW, Gross CA. PMID: 6380765.
      View in: PubMed   Mentions: 252     Fields:    Translation:Cells
    165. Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase. Cell. 1984 Sep; 38(2):371-81. Taylor WE, Straus DB, Grossman AD, Burton ZF, Gross CA, Burgess RR. PMID: 6380764.
      View in: PubMed   Mentions: 85     Fields:    Translation:Cells
    166. Regulation of cyclic AMP synthesis in Escherichia coli K-12: effects of the rpoD800 sigma mutation, glucose, and chloramphenicol. J Bacteriol. 1984 Apr; 158(1):110-4. Grossman AD, Ullmann A, Burgess RR, Gross CA. PMID: 6325382; PMCID: PMC215386.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    167. Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell. J Mol Biol. 1984 Jan 25; 172(3):283-300. Gross CA, Grossman AD, Liebke H, Walter W, Burgess RR. PMID: 6198525.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    168. Mu dX, a derivative of Mu d1 (lac Apr) which makes stable lacZ fusions at high temperature. J Bacteriol. 1983 Nov; 156(2):970-4. Baker TA, Howe MM, Gross CA. PMID: 6226649; PMCID: PMC217929.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    169. The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12. Cell. 1983 Feb; 32(2):335-49. Burton ZF, Gross CA, Watanabe KK, Burgess RR. PMID: 6186393.
      View in: PubMed   Mentions: 123     Fields:    Translation:Cells
    170. Mutations in the Ion gene of E. coli K12 phenotypically suppress a mutation in the sigma subunit of RNA polymerase. Cell. 1983 Jan; 32(1):151-9. Grossman AD, Burgess RR, Walter W, Gross CA. PMID: 6337720.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    171. Marker rescue with plasmids bearing deletions in rpoD identifies a dispensable part of E. coli sigma factor. Mol Gen Genet. 1983; 191(3):492-8. Hu JC, Gross CA. PMID: 6355770.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    172. The nucleotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E coli K12. Nucleic Acids Res. 1981 Jun 25; 9(12):2889-903. Burton Z, Burgess RR, Lin J, Moore D, Holder S, Gross CA. PMID: 6269063; PMCID: PMC326900.
      View in: PubMed   Mentions: 105     Fields:    Translation:Cells
    173. Isolation and characterization of transducing phage coding for sigma subunit of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A. 1979 Nov; 76(11):5789-93. Gross CA, Blattner FR, Taylor WE, Lowe PA, Burgess RR. PMID: 392509; PMCID: PMC411736.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    174. Altered chemical properties in three mutants of E. coli RNA polymerase sigma subunit. Mol Gen Genet. 1979 Oct 01; 175(3):251-7. Burgess RR, Gross CA, Walter W, Lowe PA. PMID: 392226.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    175. Measurement of binding constants for protein-DNA interactions by DNA-cellulose chromatography. Biochemistry. 1977 Nov 01; 16(22):4777-83. deHaseth PL, Gross CA, Burgess RR, Record MT. PMID: 911788.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    176. Quantitation of RNA polymerase subunits in Escherichia coli during exponential growth and after bacteriophage T4 infection. Molecular Genetics and Genomics. 1976 Jan 1; 143(3):291-295. Engbaek EF, Gross GC, Burgess BR. .
      View in: Publisher Site   Mentions:
    177. Non-specific DNA binding of genome regulating proteins as a biological control mechanism: I. The lac operon: equilibrium aspects. Proc Natl Acad Sci U S A. 1974 Dec; 71(12):4808-12. von Hippel PH, Revzin A, Gross CA, Wang AC. PMID: 4612528; PMCID: PMC433986.
      View in: PubMed   Mentions: 93     Fields:    Translation:Cells
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