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    Chi-yuan Hsu, MD, MS

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentMedicine
    Address521 Parnassus Ave, Clinic Sci
    San Francisco CA 94143
    Phone415-353-2379

       Biography 
       Awards and Honors
      [415] Top Doctor Marin Magazine2012
      American Society for Clinical Investigation2011

       Overview 
       Overview
      EDUCATION
      College: Yale College, BS
      Medical School: Harvard Medical School, MD
      Other Graduate Training: Yale University, MS
      Harvard School of Public Health, MSc
      Internal Medicine Residency: Beth Israel Hospital
      Nephrology Fellowship: Massachusetts General Hospital

      INTERESTS
      The overarching theme of Dr. Hsu's research relates to the study of patients with chronic kidney disease. Previous projects have refined understanding of causes of chronic kidney disease (such as obesity, diabetes and hypertension) and defined consequences of chronic kidney disease (such as anemia, cardiovascular disease and acute kidney injury). Current areas of interest include the impact of acute kidney injury on the course of chronic kidney disease and examining the transition from chronic kidney disease to end-stage renal disease. Dr. Hsu also engages in collaborative translational research of biomarkers in kidney disease.


       Bibliographic 
       Publications
      Publications by year:
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Park M, Vittinghoff E, Liu KD, Shlipak MG, Hsu CY. Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) Have Different Patterns in Heart Failure Exacerbation. Biomark Insights. 2013; 8:15-8.
        View in: PubMed
      2. Tuot DS, Plantinga LC, Judd SE, Muntner P, Hsu CY, Warnock DG, Gutiérrez OM, Safford M, Powe NR, McClellan WM. Healthy behaviors, risk factor control and awareness of chronic kidney disease. Am J Nephrol. 2013; 37(2):135-43.
        View in: PubMed
      3. Liu KD, Yang W, Anderson AH, Feldman HI, Demirjian S, Hamano T, He J, Lash J, Lustigova E, Rosas SE, Simonson MS, Tao K, Hsu CY. Urine neutrophil gelatinase-associated lipocalin levels do not improve risk prediction of progressive chronic kidney disease. Kidney Int. 2013 May; 83(5):909-14.
        View in: PubMed
      4. Bansal N, Fan D, Hsu CY, Ordonez JD, Marcus GM, Go AS. Incident atrial fibrillation and risk of end-stage renal disease in adults with chronic kidney disease. Circulation. 2013 Feb 5; 127(5):569-74.
        View in: PubMed
      5. Hsu RK, McCulloch CE, Dudley RA, Lo LJ, Hsu CY. Temporal Changes in Incidence of Dialysis-Requiring AKI. J Am Soc Nephrol. 2013 Jan; 24(1):37-42.
        View in: PubMed
      6. Bansal N, Whooley MA, Regan M, McCulloch CE, Ix JH, Epel E, Blackburn E, Lin J, Hsu CY. Association between Kidney Function and Telomere Length: The Heart and Soul Study. Am J Nephrol. 2012; 36(5):405-11.
        View in: PubMed
      7. Hsu RK, Hsu CY. We Can Diagnose AKI "Early". Clin J Am Soc Nephrol. 2012 Nov; 7(11):1741-2.
        View in: PubMed
      8. Park M, Hsu CY, Li Y, Mishra RK, Keane M, Rosas SE, Dries D, Xie D, Chen J, He J, Anderson A, Go AS, Shlipak MG. Associations between kidney function and subclinical cardiac abnormalities in CKD. J Am Soc Nephrol. 2012 Oct; 23(10):1725-34.
        View in: PubMed
      9. Huang HL, Hsu CC, Peng WD, Yen YY, Chen T, Hu CY, Shi HY, Lee CH, Chen FL, Lin PL. Analysis of influential factors associated with the smoking behavior of aboriginal schoolchildren in remote Taiwanese mountainous areas. J Sch Health. 2012 Jul; 82(7):318-27.
        View in: PubMed
      10. Shau WY, Shao YY, Yeh YC, Lin ZZ, Kuo R, Hsu CH, Hsu C, Cheng AL, Lai MS. Diabetes mellitus is associated with increased mortality in patients receiving curative therapy for hepatocellular carcinoma. Oncologist. 2012; 17(6):856-62.
        View in: PubMed
      11. Park M, Shlipak MG, Katz R, Agarwal S, Ix JH, Hsu CY, Peralta CA. Subclinical cardiac abnormalities and kidney function decline: the multi-ethnic study of atherosclerosis. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1137-44.
        View in: PubMed
      12. Bansal N, Vittinghoff E, Plantinga L, Hsu CY. Does chronic kidney disease modify the association between body mass index and cardiovascular disease risk factors. J Nephrol. 2012 May-Jun; 25(3):317-24.
        View in: PubMed
      13. Tuot DS, Plantinga LC, Hsu CY, Powe NR. Is awareness of chronic kidney disease associated with evidence-based guideline-concordant outcomes? Am J Nephrol. 2012; 35(2):191-7.
        View in: PubMed
      14. Hsu CY. Brenner and Rector's The Kidney. Chapter 19: Epidemiology of Kidney Disease. 2012; 1:728-741.
      15. Shao YY, Chen PJ, Lin ZZ, Huang CC, Ding YH, Lee YH, Hsu CH, Cheng AL. Impact of baseline hepatitis B viral DNA levels on survival of patients with advanced hepatocellular carcinoma. Anticancer Res. 2011 Nov; 31(11):4007-11.
        View in: PubMed
      16. Yang SH, Kuo YH, Tien YW, Hsu C, Hsu CH, Kuo SH, Cheng AL. Inferior survival of advanced pancreatic cancer patients who received gemcitabine-based chemotherapy but did not participate in clinical trials. Oncology. 2011; 81(3-4):143-50.
        View in: PubMed
      17. Hsu CY, Propert K, Xie D, Hamm L, He J, Miller E, Ojo A, Shlipak M, Teal V, Townsend R, Weir M, Wilson J, Feldman H. Measured GFR does not outperform estimated GFR in predicting CKD-related complications. J Am Soc Nephrol. 2011 Oct; 22(10):1931-7.
        View in: PubMed
      18. Bansal N, Hsu CY, Chandra M, Iribarren C, Fortmann SP, Hlatky MA, Go AS. Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study. BMC Nephrol. 2011; 12:44.
        View in: PubMed
      19. Chang WC, Wahlqvist ML, Chang HY, Hsu CC, Lee MS, Wang WS, Hsiung CA. A bean-free diet increases the risk of all-cause mortality among Taiwanese women: the role of the metabolic syndrome. Public Health Nutr. 2012 Apr; 15(4):663-72.
        View in: PubMed
      20. Tuot DS, Plantinga LC, Hsu CY, Jordan R, Burrows NR, Hedgeman E, Yee J, Saran R, Powe NR. Chronic kidney disease awareness among individuals with clinical markers of kidney dysfunction. Clin J Am Soc Nephrol. 2011 Aug; 6(8):1838-44.
        View in: PubMed
      21. Isakova T, Xie H, Yang W, Xie D, Anderson AH, Scialla J, Wahl P, Gutiérrez OM, Steigerwalt S, He J, Schwartz S, Lo J, Ojo A, Sondheimer J, Hsu CY, Lash J, Leonard M, Kusek JW, Feldman HI, Wolf M. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA. 2011 Jun 15; 305(23):2432-9.
        View in: PubMed
      22. Hsu RK, Hsu CY. Proteinuria and reduced glomerular filtration rate as risk factors for acute kidney injury. Curr Opin Nephrol Hypertens. 2011 May; 20(3):211-7.
        View in: PubMed
      23. Ch'ang HJ, Lin YL, Wang HP, Chiu YF, Chang MC, Hsu CH, Tien YW, Chen JS, Hsieh RK, Lin PW, Shan YS, Cheng AL, Chang JY, Whang-Peng J, Hwang TL, Chen LT. Induction chemotherapy with gemcitabine, oxaliplatin, and 5-fluorouracil/leucovorin followed by concomitant chemoradiotherapy in patients with locally advanced pancreatic cancer: a Taiwan cooperative oncology group phase II study. Int J Radiat Oncol Biol Phys. 2011 Dec 1; 81(5):e749-57.
        View in: PubMed
      24. Wen CP, Chan HT, Tsai MK, Cheng TY, Chung WS, Chang YC, Hsu HL, Tsai SP, Tsao CK, Man Wai JP, Hsu CC. Attributable mortality burden of metabolic syndrome: comparison with its individual components. Eur J Cardiovasc Prev Rehabil. 2011 Aug; 18(4):561-73.
        View in: PubMed
      25. Wang ZJ, Kumar R, Banerjee S, Hsu CY. Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: preliminary experience. J Magn Reson Imaging. 2011 Mar; 33(3):655-60.
        View in: PubMed
      26. Lee P, Johansen K, Hsu CY. End-stage renal disease preceded by rapid declines in kidney function: a case series. BMC Nephrol. 2011; 12:5.
        View in: PubMed
      27. Hsu CY. Where is the epidemic in kidney disease? J Am Soc Nephrol. 2010 Oct; 21(10):1607-11.
        View in: PubMed
      28. Go AS, Parikh CR, Ikizler TA, Coca S, Siew ED, Chinchilli VM, Hsu CY, Garg AX, Zappitelli M, Liu KD, Reeves WB, Ghahramani N, Devarajan P, Faulkner GB, Tan TC, Kimmel PL, Eggers P, Stokes JB. The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods. BMC Nephrol. 2010; 11:22.
        View in: PubMed
      29. Huang MC, Hsu CC, Wang HS, Shin SJ. Prospective randomized controlled trial to evaluate effectiveness of registered dietitian-led diabetes management on glycemic and diet control in a primary care setting in Taiwan. Diabetes Care. 2010 Feb; 33(2):233-9.
        View in: PubMed
      30. Lo LJ, Go AS, Chertow GM, McCulloch CE, Fan D, Ordoñez JD, Hsu CY. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int. 2009 Oct; 76(8):893-9.
        View in: PubMed
      31. Liu KD, Lo L, Hsu CY. Some methodological issues in studying the long-term renal sequelae of acute kidney injury. Curr Opin Nephrol Hypertens. 2009 May; 18(3):241-5.
        View in: PubMed
      32. Hsu CY, Chertow GM, McCulloch CE, Fan D, Ordoñez JD, Go AS. Nonrecovery of kidney function and death after acute on chronic renal failure. Clin J Am Soc Nephrol. 2009 May; 4(5):891-8.
        View in: PubMed
      33. Nguyen S, Choi HK, Lustig RH, Hsu CY. Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents. J Pediatr. 2009 Jun; 154(6):807-13.
        View in: PubMed
      34. Hsu CY, Iribarren C, McCulloch CE, Darbinian J, Go AS. Risk factors for end-stage renal disease: 25-year follow-up. Arch Intern Med. 2009 Feb 23; 169(4):342-50.
        View in: PubMed
      35. Grubbs V, Gregorich SE, Perez-Stable EJ, Hsu CY. Health literacy and access to kidney transplantation. Clin J Am Soc Nephrol. 2009 Jan; 4(1):195-200.
        View in: PubMed
      36. Hsu CY. FGF-23 and outcomes research--when physiology meets epidemiology. N Engl J Med. 2008 Aug 7; 359(6):640-2.
        View in: PubMed
      37. Hsu CY, Ordoñez JD, Chertow GM, Fan D, McCulloch CE, Go AS. The risk of acute renal failure in patients with chronic kidney disease. Kidney Int. 2008 Jul; 74(1):101-7.
        View in: PubMed
      38. Nguyen S, McCulloch C, Brakeman P, Portale A, Hsu CY. Being overweight modifies the association between cardiovascular risk factors and microalbuminuria in adolescents. Pediatrics. 2008 Jan; 121(1):37-45.
        View in: PubMed
      39. Hsu CY, McCulloch CE, Fan D, Ordoñez JD, Chertow GM, Go AS. Community-based incidence of acute renal failure. Kidney Int. 2007 Jul; 72(2):208-12.
        View in: PubMed
      40. Hsu CY. Linking the population epidemiology of acute renal failure, chronic kidney disease and end-stage renal disease. Curr Opin Nephrol Hypertens. 2007 May; 16(3):221-6.
        View in: PubMed
      41. Joff MM, Small D, Hsu CY. Statist Sci. Defining and estimating intervention effects for groups that will develop an auxiliary outcome. 2007; 22(1):74-97.
      42. Hsu CY, Go AS, McCulloch CE, Darbinian J, Iribarren C. Exploring secular trends in the likelihood of receiving treatment for end-stage renal disease. Clin J Am Soc Nephrol. 2007 Jan; 2(1):81-8.
        View in: PubMed
      43. Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006 Jan 3; 144(1):21-8.
        View in: PubMed
      44. Hsu CY, McCulloch CE, Darbinian J, Go AS, Iribarren C. Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease. Arch Intern Med. 2005 Apr 25; 165(8):923-8.
        View in: PubMed
      45. Lo JC, Chertow GM, Go AS, Hsu CY. Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease. Kidney Int. 2005 Mar; 67(3):1047-52.
        View in: PubMed
      46. Shah SJ, Hsu CY. Has acetylcysteine use changed the incidence of contrast nephropathy in hospitalized patients? A before-after study. Am J Med. 2004 Dec 15; 117(12):948-52.
        View in: PubMed
      47. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004 Sep 23; 351(13):1296-305.
        View in: PubMed
      48. Hsu CY, Vittinghoff E, Lin F, Shlipak MG. The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency. Ann Intern Med. 2004 Jul 20; 141(2):95-101.
        View in: PubMed
      49. O'Hare AM, Glidden DV, Fox CS, Hsu CY. High prevalence of peripheral arterial disease in persons with renal insufficiency: results from the National Health and Nutrition Examination Survey 1999-2000. Circulation. 2004 Jan 27; 109(3):320-3.
        View in: PubMed
      50. Hsu CY, Lin F, Vittinghoff E, Shlipak MG. Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States. J Am Soc Nephrol. 2003 Nov; 14(11):2902-7.
        View in: PubMed
      51. Chen ML, Hsu CY. Should the K/DOQI definition of chronic kidney disease be changed? Am J Kidney Dis. 2003 Oct; 42(4):623-5.
        View in: PubMed
      52. Feldman HI, Appel LJ, Chertow GM, Cifelli D, Cizman B, Daugirdas J, Fink JC, Franklin-Becker ED, Go AS, Hamm LL, He J, Hostetter T, Hsu CY, Jamerson K, Joffe M, Kusek JW, Landis JR, Lash JP, Miller ER, Mohler ER, Muntner P, Ojo AO, Rahman M, Townsend RR, Wright JT. The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods. J Am Soc Nephrol. 2003 Jul; 14(7 Suppl 2):S148-53.
        View in: PubMed
      53. Kramer HJ, Nguyen QD, Curhan G, Hsu CY. Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus. JAMA. 2003 Jun 25; 289(24):3273-7.
        View in: PubMed
      54. Hsu CY, McCulloch CE, Curhan GC. Iron status and hemoglobin level in chronic renal insufficiency. J Am Soc Nephrol. 2002 Nov; 13(11):2783-6.
        View in: PubMed
      55. Hsu CY, Chertow GM. Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency. Nephrol Dial Transplant. 2002 Aug; 17(8):1419-25.
        View in: PubMed
      56. Hsu CY, Chertow GM, Curhan GC. Methodological issues in studying the epidemiology of mild to moderate chronic renal insufficiency. Kidney Int. 2002 May; 61(5):1567-76.
        View in: PubMed
      57. Hsu CY, Cummings SR, McCulloch CE, Chertow GM. Bone mineral density is not diminished by mild to moderate chronic renal insufficiency. Kidney Int. 2002 May; 61(5):1814-20.
        View in: PubMed
      58. Hsu CY, McCulloch CE, Curhan GC. Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: results from the Third National Health and Nutrition Examination Survey. J Am Soc Nephrol. 2002 Feb; 13(2):504-10.
        View in: PubMed
      59. Hsu CY, Bates DW, Kuperman GJ, Curhan GC. Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency. Am J Hypertens. 2001 Dec; 14(12):1219-25.
        View in: PubMed
      60. Hsu CY. Does treatment of non-malignant hypertension reduce the incidence of renal dysfunction? A meta-analysis of 10 randomised, controlled trials. J Hum Hypertens. 2001 Feb; 15(2):99-106.
        View in: PubMed
      61. Hsu CY, Bates DW, Kuperman GJ, Curhan GC. Relationship between hematocrit and renal function in men and women. Kidney Int. 2001 Feb; 59(2):725-31.
        View in: PubMed
      62. Hsu CY, Bates DW, Kuperman GJ, Curhan GC. Diabetes, hemoglobin A(1c), cholesterol, and the risk of moderate chronic renal insufficiency in an ambulatory population. Am J Kidney Dis. 2000 Aug; 36(2):272-81.
        View in: PubMed
      63. Hsu CY, Chertow GM. Chronic renal confusion: insufficiency, failure, dysfunction, or disease. Am J Kidney Dis. 2000 Aug; 36(2):415-8.
        View in: PubMed
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