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    Christian Hoppmann, PhD

    TitleAssociate Specialist
    SchoolUCSF School of Pharmacy
    DepartmentPharmaceutical Chemistry
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Awards and Honors
      The Salk Institute for Biological Studies2013Cancer Center Pilot Grant
      American Peptide Society2013Travel Award
      The Salk Institute for Biological Studies2013Postdoc Pioneer Fund
      The Salk Institute for Biological Studies2012Research Fellowship, German Research Foundation (DFG)
      Technische Universität Berlin (Germany)2010Ph.D. with highest honor: "summa cum laude"

      Collapse Overview 
      Collapse Interests
      Photoswitchable Click Amino Acids, Expanded Genetic Code, Protein Engineering and Modification, Unnatural Amino Acid Mutagenesis, Bioconjugation and Crosslinking, Protein-Protein Interactions, Optobiology, Peptide Therapeutics, Stapled Peptides, Cancer, Muscle Diseases, Alzheimer

      Collapse ORNG Applications 
      Collapse In The News

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kobayashi T, Hoppmann C, Yang B, Wang L. Using Protein-Confined Proximity to Determine Chemical Reactivity. J Am Chem Soc. 2016 Oct 31. PMID: 27797495.
        View in: PubMed
      2. Alamudi SH, Satapathy R, Kim J, Su D, Ren H, Das R, Hu L, Alvarado-Martínez E, Lee JY, Hoppmann C, Peña-Cabrera E, Ha HH, Park HS, Wang L, Chang YT, et al. Development of background-free tame fluorescent probes for intracellular live cell imaging. Nat Commun. 2016; 7:11964. PMID: 27321135.
        View in: PubMed
      3. Hoppmann C, Wang L. Proximity-enabled bioreactivity to generate covalent peptide inhibitors of p53-Mdm4. Chem Commun (Camb). 2016 Apr 14; 52(29):5140-3. PMID: 26996321.
        View in: PubMed
      4. Hoppmann C, Maslennikov I, Choe S, Wang L. In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light. J Am Chem Soc. 2015 Sep 9; 137(35):11218-21. PMID: 26301538.
        View in: PubMed
      5. Li YC, Rodewald LW, Hoppmann C, Wong ET, Lebreton S, Safar P, Patek M, Wang L, Wertman KF, Wahl GM. A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time. Cell Rep. 2014 Dec 11; 9(5):1946-58. PMID: 25464845; PMCID: PMC4269221.
      6. Hoppmann C, Lacey VK, Louie GV, Wei J, Noel JP, Wang L. Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cells. Angew Chem Int Ed Engl. 2014 Apr 7; 53(15):3932-6. PMID: 24615769; PMCID: PMC4051619.
      7. Hoppmann, C.; Alexiev, U.; Irran, E.; Rück-Braun, K. . Synthesis and Fluorescence of Xanthone Amino Acids. Tetrahedron Letters. 2013; 34(54):4585-4587.
      8. Hoppmann C, Barucker C, Lorenz D, Multhaup G, Beyermann M. Light-controlled toxicity of engineered amyloid ß-peptides. Chembiochem. 2012 Dec 21; 13(18):2657-60. PMID: 23161824.
        View in: PubMed
      9. Hoppmann C, Kühne R, Beyermann M. Intramolecular bridges formed by photoswitchable click amino acids. Beilstein J Org Chem. 2012; 8:884-9. PMID: 23015838; PMCID: PMC3388878.
      10. Regner N, Herzog TT, Haiser K, Hoppmann C, Beyermann M, Sauermann J, Engelhard M, Cordes T, Rück-Braun K, Zinth W. Light-switchable hemithioindigo-hemistilbene-containing peptides: ultrafast spectroscopy of the Z ? E isomerization of the chromophore and the structural dynamics of the peptide moiety. J Phys Chem B. 2012 Apr 12; 116(14):4181-91. PMID: 22423868.
        View in: PubMed
      11. Hoppmann C, Schmieder P, Heinrich N, Beyermann M. Photoswitchable click amino acids: light control of conformation and bioactivity. Chembiochem. 2011 Nov 25; 12(17):2555-9. PMID: 21998087.
        View in: PubMed
      12. Hoppmann C, Schmieder P, Domaing P, Vogelreiter G, Eichhorst J, Wiesner B, Morano I, Rück-Braun K, Beyermann M. Photocontrol of contracting muscle fibers. Angew Chem Int Ed Engl. 2011 Aug 8; 50(33):7699-702. PMID: 21739542.
        View in: PubMed
      13. Hoppmann C, Seedorff S, Richter A, Fabian H, Schmieder P, Rück-Braun K, Beyermann M. Light-directed protein binding of a biologically relevant beta-sheet. Angew Chem Int Ed Engl. 2009; 48(36):6636-9. PMID: 19662671.
        View in: PubMed
      14. Cordes T, Heinz B, Regner N, Hoppmann C, Schrader TE, Summerer W, Rück-Braun K, Zinth W. Photochemical Z-->E isomerization of a hemithioindigo/hemistilbene omega-amino acid. Chemphyschem. 2007 Aug 6; 8(11):1713-21. PMID: 17614347.
        View in: PubMed
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