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Daisuke Kudo, MD, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentAnesthesia
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-206-8958
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    Collapse Biography 
    Collapse Education and Training
    Tohoku UniversityM.D.2002Medicine
    Tohoku University Graduate SchoolPh.D.2013Medicine

    Collapse Overview 
    Collapse Overview
    Specialty & Interest
    Sepsis, Trauma, Burn, Cardiac arrest
    Inflammation, Immunity, Coagulation & Fibrinolysis
    Long-term outcome


    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kagiya T, Shimoda H, Narita H, Odagiri T, Watanabe S, Ishido K, Kudo D, Kimura N, Wakiya T, Hakamada K. Microanatomical profiles on the lymphatic system in the human ampulla of Vater (immunohistochemistry and scanning electron microscopy). J Hepatobiliary Pancreat Sci. 2017 Aug 28. PMID: 28846834.
      View in: PubMed
    2. Hayakawa M, Maekawa K, Kushimoto S, Kato H, Sasaki J, Ogura H, Matsuoka T, Uejima T, Morimura N, Ishikura H, Hagiwara A, Takeda M, Kaneko N, Saitoh D, Kudo D, Kanemura T, Shibusawa T, Furugori S, Nakamura Y, Shiraishi A, Murata K, Mayama G, Yaguchi A, Kim S, Takasu O, Nishiyama K. Hyperfibrinolysis in severe isolated traumatic brain injury may occur without tissue hypoperfusion: a retrospective observational multicentre study. Crit Care. 2017 Aug 23; 21(1):222. PMID: 28830477.
      View in: PubMed
    3. Iizuka Y, Sanui M, Sasabuchi Y, Lefor AK, Hayakawa M, Saito S, Uchino S, Yamakawa K, Kudo D, Takimoto K, Mayumi T, Azuhata T, Ito F, Yoshihiro S, Hayakawa K, Nakashima T, Ogura T, Noda E, Nakamura Y, Sekine R, Yoshikawa Y, Sekino M, Ueno K, Okuda Y, Watanabe M, Tampo A, Saito N, Kitai Y, Takahashi H, Kobayashi I, Kondo Y, Matsunaga W, Nachi S, Miike T, Takahashi H, Takauji S, Umakoshi K, Todaka T, Kodaira H, Andoh K, Kasai T, Iwashita Y, Arai H, Murata M, Yamane M, Shiga K, Hori N. Low-dose immunoglobulin G is not associated with mortality in patients with sepsis and septic shock. Crit Care. 2017 Jul 13; 21(1):181. PMID: 28701223.
      View in: PubMed
    4. Wakiya T, Kudo D, Ishido K, Kimura N, Yakoshi Y, Toyoki Y, Kijima H, Hakamada K. Effect of age on the development of chemotherapy-associated liver injury in colorectal cancer liver metastasis. Mol Clin Oncol. 2017 Aug; 7(2):200-204. PMID: 28781785.
      View in: PubMed
    5. Kimura N, Young AL, Toyoki Y, Wyatt JI, Toogood GJ, Hidalgo E, Prasad KR, Kudo D, Ishido K, Hakamada K, Lodge JPA. Radical operation for hilar cholangiocarcinoma in comparable Eastern and Western centers: Outcome analysis and prognostic factors. Surgery. 2017 Sep; 162(3):500-514. PMID: 28551378.
      View in: PubMed
    6. Saito T, Ishido K, Kudo D, Kimura N, Wakiya T, Nakayama Y, Hakamada K. Combination therapy with gemcitabine and nab-paclitaxel for locally advanced unresectable pancreatic cancer. Mol Clin Oncol. 2017 Jun; 6(6):963-967. PMID: 28588798.
      View in: PubMed
    7. Kudo D, Suto A, Hakamada K. The Development of a Novel Therapeutic Strategy to Target Hyaluronan in the Extracellular Matrix of Pancreatic Ductal Adenocarcinoma. Int J Mol Sci. 2017 Mar 09; 18(3). PMID: 28282922.
      View in: PubMed
    8. Kasukawa Y, Miyakoshi N, Hongo M, Ishikawa Y, Kudo D, Suzuki M, Mizutani T, Kimura R, Ono Y, Shimada Y. Age-related changes in muscle strength and spinal kyphosis angles in an elderly Japanese population. Clin Interv Aging. 2017; 12:413-420. PMID: 28260870.
      View in: PubMed
    9. Godo S, Yoshida Y, Fujita M, Kudo D, Nomura R, Shimokawa H, Kushimoto S. The Dramatic Recovery of a Patient with Biguanide-associated Severe Lactic Acidosis Following Thiamine Supplementation. Intern Med. 2017; 56(4):455-459. PMID: 28202871.
      View in: PubMed
    10. Ishikawa Y, Miyakoshi N, Hongo M, Kasukawa Y, Kudo D, Shimada Y. Relationships among spinal mobility and sagittal alignment of spine and lower extremity to quality of life and risk of falls. Gait Posture. 2017 Mar; 53:98-103. PMID: 28126694.
      View in: PubMed
    11. Nakamura Y, Ishikura H, Kushimoto S, Kiyomi F, Kato H, Sasaki J, Ogura H, Matsuoka T, Uejima T, Morimura N, Hayakawa M, Hagiwara A, Takeda M, Kaneko N, Saitoh D, Kudo D, Maekawa K, Kanemura T, Shibusawa T, Hagihara Y, Furugori S, Shiraishi A, Murata K, Mayama G, Yaguchi A, Kim S, Takasu O, Nishiyama K. Fibrinogen level on admission is a predictor for massive transfusion in patients with severe blunt trauma: Analyses of a retrospective multicentre observational study. Injury. 2017 Mar; 48(3):674-679. PMID: 28122682.
      View in: PubMed
    12. Godo S, Irino S, Nakagawa A, Kawazoe Y, Fujita M, Kudo D, Nomura R, Shimokawa H, Kushimoto S. Diagnosis and Management of Patients with Paroxysmal Sympathetic Hyperactivity following Acute Brain Injuries Using a Consensus-Based Diagnostic Tool: A Single Institutional Case Series. Tohoku J Exp Med. 2017; 243(1):11-18. PMID: 28890524.
      View in: PubMed
    13. Kudo D, Shimizu M, Kuroda A, Suyama T, Shinagawa A, Ito S. Myelodysplastic syndrome with neutrophilic dermatosis successfully treated with azacitidine. Rinsho Ketsueki. 2017; 58(6):607-612. PMID: 28679990.
      View in: PubMed
    14. Hayakawa M, Kudo D, Saito S, Uchino S, Yamakawa K, Iizuka Y, Sanui M, Takimoto K, Mayumi T, Ono K, Azuhata T, Ito F, Yoshihiro S, Hayakawa K, Nakashima T, Ogura T, Noda E, Nakamura Y, Sekine R, Yoshikawa Y, Sekino M, Ueno K, Okuda Y, Watanabe M, Tampo A, Saito N, Kitai Y, Takahashi H, Kobayashi I, Kondo Y, Matsunaga W, Nachi S, Miike T, Takahashi H, Takauji S, Umakoshi K, Todaka T, Kodaira H, Andoh K, Kasai T, Iwashita Y, Arai H, Murata M, Yamane M, Shiga K, Hori N. Antithrombin Supplementation and Mortality in Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study. Shock. 2016 Dec; 46(6):623-631. PMID: 27548460.
      View in: PubMed
    15. Kudo D, Kushimoto S, Shiraishi A, Ogura H, Hagiwara A, Saitoh D. The impact of preinjury antithrombotic medication on hemostatic interventions in trauma patients. Am J Emerg Med. 2017 Jan; 35(1):62-65. PMID: 27745921.
      View in: PubMed
    16. Endo A, Shiraishi A, Otomo Y, Kushimoto S, Saitoh D, Hayakawa M, Ogura H, Murata K, Hagiwara A, Sasaki J, Matsuoka T, Uejima T, Morimura N, Ishikura H, Takeda M, Kaneko N, Kato H, Kudo D, Kanemura T, Shibusawa T, Hagiwara Y, Furugori S, Nakamura Y, Maekawa K, Mayama G, Yaguchi A, Kim S, Takasu O, Nishiyama K. Development of Novel Criteria of the "Lethal Triad" as an Indicator of Decision Making in Current Trauma Care: A Retrospective Multicenter Observational Study in Japan. Crit Care Med. 2016 Sep; 44(9):e797-803. PMID: 27046085.
      View in: PubMed
    17. Ohbe H, Kudo D, Yamanouchi S, Kushimoto S. Decreased a disintegrin-like and metalloprotease with thrombospondin type 1 motif 13 activity and neurologic outcome in patients with successful resuscitation of out-of-hospital cardiac arrest: A prospective observational study. J Crit Care. 2017 Feb; 37:13-18. PMID: 27610586.
      View in: PubMed
    18. Yamakawa K, Umemura Y, Hayakawa M, Kudo D, Sanui M, Takahashi H, Yoshikawa Y, Hamasaki T, Fujimi S. Benefit profile of anticoagulant therapy in sepsis: a nationwide multicentre registry in Japan. Crit Care. 2016 Jul 29; 20(1):229. PMID: 27472991; PMCID: PMC4966726.
    19. Seo R, Kudo D, Gu Y, Yano H, Aoyagi T, Omura T, Irino S, Kaku M, Kushimoto S. Invasive liver abscess syndrome caused by Klebsiella pneumoniae with definite K2 serotyping in Japan: a case report. Surg Case Rep. 2016 Dec; 2(1):72. PMID: 27457077; PMCID: PMC4960081.
    20. Omura T, Kushimoto S, Yamanouchi S, Kudo D, Miyagawa N. High-mobility group box 1 is associated with neurological outcome in patients with post-cardiac arrest syndrome after out-of-hospital cardiac arrest. J Intensive Care. 2016; 4:37. PMID: 27247778; PMCID: PMC4886401.
    21. Hayakawa M, Yamakawa K, Saito S, Uchino S, Kudo D, Iizuka Y, Sanui M, Takimoto K, Mayumi T, Ono K. Recombinant human soluble thrombomodulin and mortality in sepsis-induced disseminated intravascular coagulation. A multicentre retrospective study. Thromb Haemost. 2016 Jun 02; 115(6):1157-66. PMID: 26939575.
      View in: PubMed
    22. Hayakawa M, Maekawa K, Kushimoto S, Kato H, Sasaki J, Ogura H, Matauoka T, Uejima T, Morimura N, Ishikura H, Hagiwara A, Takeda M, Kaneko N, Saitoh D, Kudo D, Kanemura T, Shibusawa T, Furugori S, Nakamura Y, Shiraishi A, Murata K, Mayama G, Yaguchi A, Kim S, Takasu O, Nishiyama K. HIGH D-DIMER LEVELS PREDICT A POOR OUTCOME IN PATIENTS WITH SEVERE TRAUMA, EVEN WITH HIGH FIBRINOGEN LEVELS ON ARRIVAL: A MULTICENTER RETROSPECTIVE STUDY. Shock. 2016 Mar; 45(3):308-14. PMID: 26882403.
      View in: PubMed
    23. Nakagawa A, Ohtani K, Goda K, Kudo D, Arafune T, Washio T, Tominaga T. Mechanism of Traumatic Brain Injury at Distant Locations After Exposure to Blast Waves: Preliminary Results from Animal and Phantom Experiments. Acta Neurochir Suppl. 2016; 122:3-7. PMID: 27165867.
      View in: PubMed
    24. Matsumura T, Osaki S, Kudo D, Furukawa H, Nakagawa A, Abe Y, Yamanouchi S, Egawa S, Tominaga T, Kushimoto S. Water supply facility damage and water resource operation at disaster base hospitals in miyagi prefecture in the wake of the Great East Japan Earthquake. Prehosp Disaster Med. 2015 Apr; 30(2):193-8. PMID: 25665093.
      View in: PubMed
    25. Maezawa S, Kudo D, Furukawa H, Nakagawa A, Yamanouchi S, Matsumura T, Egawa S, Tominaga T, Kushimoto S. Radiology diagnostic devices under emergency electric power at disaster base hospitals during the acute phase of the Great East Japan Earthquake: results of a survey of all disaster base hospitals in Miyagi Prefecture. Disaster Med Public Health Prep. 2014 Dec; 8(6):548-52. PMID: 25491761.
      View in: PubMed
    26. Furukawa H, Kudo D, Nakagawa A, Matsumura T, Abe Y, Konishi R, Yamanouchi S, Ishibashi S, Kobayashi M, Narita N, Washio T, Arafune T, Tominaga T, Kushimoto S. Hypothermia in victims of the great East Japan earthquake: a survey in Miyagi prefecture. Disaster Med Public Health Prep. 2014 Oct; 8(5):379-89. PMID: 25215601.
      View in: PubMed
    27. Tagami T, Nakamura T, Kushimoto S, Tosa R, Watanabe A, Kaneko T, Fukushima H, Rinka H, Kudo D, Uzu H, Murai A, Takatori M, Izumino H, Kase Y, Seo R, Takahashi H, Kitazawa Y, Yamaguchi J, Sugita M, Takahashi H, Kuroki Y, Kanemura T, Morisawa K, Saito N, Irahara T, Yokota H. Early-phase changes of extravascular lung water index as a prognostic indicator in acute respiratory distress syndrome patients. Ann Intensive Care. 2014; 4:27. PMID: 25593743; PMCID: PMC4273855.
    28. Nakayachi K, Kudo D, Ozaki T. [Trust in organizations concerned with risks of the Great East Japan Earthquake]. Shinrigaku Kenkyu. 2014 Jun; 85(2):139-47. PMID: 25016834.
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    29. Kudo D, Furukawa H, Nakagawa A, Abe Y, Washio T, Arafune T, Sato D, Yamanouchi S, Ochi S, Tominaga T, Kushimoto S. Reliability of telecommunications systems following a major disaster: survey of secondary and tertiary emergency institutions in Miyagi Prefecture during the acute phase of the 2011 Great East Japan Earthquake. Prehosp Disaster Med. 2014 Apr; 29(2):204-8. PMID: 24555870.
      View in: PubMed
    30. Kushimoto S, Yamanouchi S, Endo T, Sato T, Nomura R, Fujita M, Kudo D, Omura T, Miyagawa N, Sato T. Body temperature abnormalities in non-neurological critically ill patients: a review of the literature. J Intensive Care. 2014; 2(1):14. PMID: 25520830; PMCID: PMC4267592.
    31. Tanno D, Akahori Y, Toyama M, Sato K, Kudo D, Abe Y, Miyasaka T, Yamamoto H, Ishii K, Kanno E, Maruyama R, Kushimoto S, Iwakura Y, Kawakami K. Involvement of Gr-1 dull+ cells in the production of TNF-a and IL-17 and exacerbated systemic inflammatory response caused by lipopolysaccharide. Inflammation. 2014 Feb; 37(1):186-95. PMID: 24022599.
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    32. Kudo D, Furukawa H, Nakagawa A, Yamanouchi S, Koido Y, Matsumura T, Abe Y, Konishi R, Matoba M, Tominaga T, Kushimoto S. Resources for business continuity in disaster-based hospitals in the great East Japan earthquake: survey of Miyagi Prefecture disaster base hospitals and the prefectural disaster medicine headquarters. Disaster Med Public Health Prep. 2013 Oct; 7(5):461-6. PMID: 24274125.
      View in: PubMed
    33. Kudo D, Uno K, Aoyagi T, Akahori Y, Ishii K, Kanno E, Maruyama R, Kushimoto S, Kaku M, Kawakami K. Low-dose interferon-a treatment improves survival and inflammatory responses in a mouse model of fulminant acute respiratory distress syndrome. Inflammation. 2013 Aug; 36(4):812-20. PMID: 23407996.
      View in: PubMed
    34. Yamanouchi S, Kudo D, Yamada M, Miyagawa N, Furukawa H, Kushimoto S. Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: time course and the association with clinical status. J Crit Care. 2013 Dec; 28(6):1027-31. PMID: 23787023.
      View in: PubMed
    35. Nakagawa A, Furukawa H, Konishi R, Kudo D, Matsumura T, Sato D, Abe Y, Washio T, Arafune T, Yamanouchi S, Kushimoto S, Tominaga T. The great East Japan earthquake: lessons learned at Tohoku University Hospital during the first 72 hours. IEEE Pulse. 2013 May; 4(3):20-7. PMID: 23709136.
      View in: PubMed
    36. Kudo D, Sasaki J, Akaishi S, Yamanouchi S, Koakutsu T, Endo T, Sato T, Nomura R, Yuzawa H, Kobayashi M, Shinozawa Y, Kushimoto S. Efficacy of a high FFP:PRBC transfusion ratio on the survival of severely injured patients: a retrospective study in a single tertiary emergency center in Japan. Surg Today. 2014 Apr; 44(4):653-61. PMID: 23420095.
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    37. Sasaki J, Yamanouchi S, Kudo D, Endo T, Nomura R, Takuma K, Kushimoto S, Shinozawa Y, Kishino S, Hori S, Aikawa N. Micafungin concentrations in the plasma and burn eschar of severely burned patients. Antimicrob Agents Chemother. 2012 Feb; 56(2):1113-5. PMID: 22083486; PMCID: PMC3264244.
    38. Ishido K, Toyoki Y, Kudo D, Kimura N, Yamana D, Miura T, Tsutsumi S, Muroya T, Yoshikawa T, Ogasawara H, Yonaiyama S, Narumi S, Hakamada K. Effects of S-1 as a second-line chemotherapy for patients with relapsed pancreatic cancer. Oncol Lett. 2011 Nov; 2(6):1313-1317. PMID: 22848308.
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    39. Hagiwara A, Kimura A, Kato H, Mizushima Y, Matsuoka T, Takeda M, Uejima T, Hagiwara Y, Sakamoto Y, Kudo D, Sasaki J. Hemodynamic reactions in patients with hemorrhagic shock from blunt trauma after initial fluid therapy. J Trauma. 2010 Nov; 69(5):1161-8. PMID: 20489665.
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    40. Yamanouchi S, Kudo D, Endo T, Kitano Y, Shinozawa Y. Blood N-terminal proBNP as a potential indicator of cardiac preload in patients with high volume load. Tohoku J Exp Med. 2010 Jul; 221(3):175-80. PMID: 20505308.
      View in: PubMed
    41. Kudo D, Yamamura H, Nishiuchi T, Ishikawa K, Mizushima Y, Matsuoka T, Yokota J. Anterior and posterior ischemic optic neuropathy related to massive fluid resuscitation after blunt trauma. J Trauma. 2010 Mar; 68(3):E67-70. PMID: 20220404.
      View in: PubMed
    42. Xie XQ, Shinozawa Y, Sasaki J, Takuma K, Akaishi S, Yamanouchi S, Endo T, Nomura R, Kobayashi M, Kudo D, Hojo N. The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. J Surg Res. 2008 May 15; 146(2):298-303. PMID: 17997414.
      View in: PubMed
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