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Dolores Shoback, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address4150 Clement St
San Francisco CA 94121
Phone415-575-0552
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    Collapse Biography 
    Collapse Education and Training
    Johns HopkinsM.D.1977School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms Underlying Hormonal Regulation of Fracture Repair
    NIH IP1BX001599Jan 1, 2012 - Dec 31, 2015
    Role: Principal Investigator
    Conditional Knockout of Calcium Receptors in Bone Cells
    NIH R01AR055588Jul 10, 2009 - Apr 30, 2014
    Role: Principal Investigator
    DESENSITIZATION AND DOWN REGULATION OF CALCIUM RECEPTORS
    NIH R01DK055846Jul 1, 1999 - Oct 31, 2004
    Role: Principal Investigator
    REGULATION OF INTRACELLULAR CALCIUM IN PARATHYROID CELLS
    NIH R01DK043400Jun 1, 1991 - Mar 31, 2000
    Role: Principal Investigator
    REGULATION OF PARATHORMONE SECRETION IN DISPERSED CELLS
    NIH R29DK039594Apr 1, 1988 - Dec 31, 1991
    Role: Principal Investigator
    REGULATION OF PARATHORMONE SECRETION IN DISPERSED CELLS
    NIH R23DK036919Apr 1, 1986 - Mar 31, 1989
    Role: Principal Investigator
    Diabetes, Endocrinology &Metabolism Training Grant
    NIH T32DK007418Jul 1, 1981 - Jun 30, 2016
    Role: Principal Investigator
    MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
    NIH P60AR020684Sep 15, 1977 - Dec 31, 2003
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shoback D. Does parathyroid hormone control bone quality? Endocrine. 2017 Jan 02. PMID: 28042646.
      View in: PubMed
    2. Clarke BL, Vokes TJ, Bilezikian JP, Shoback DM, Lagast H, Mannstadt M. Effects of parathyroid hormone rhPTH(1-84) on phosphate homeostasis and vitamin D metabolism in hypoparathyroidism: REPLACE phase 3 study. Endocrine. 2016 Oct 12. PMID: 27734257.
      View in: PubMed
    3. Shoback DM, Bilezikian JP, Costa AG, Dempster D, Dralle H, Khan AA, Peacock M, Raffaelli M, Silva BC, Thakker RV, Vokes T, Bouillon R. Presentation of Hypoparathyroidism: Etiologies and Clinical Features. J Clin Endocrinol Metab. 2016 Jun; 101(6):2300-12. PMID: 26943721.
      View in: PubMed
    4. Brandi ML, Bilezikian JP, Shoback D, Bouillon R, Clarke BL, Thakker RV, Khan AA, Potts JT. Management of Hypoparathyroidism: Summary Statement and Guidelines. J Clin Endocrinol Metab. 2016 Jun; 101(6):2273-83. PMID: 26943719.
      View in: PubMed
    5. Santa Maria C, Cheng Z, Li A, Wang J, Shoback D, Tu CL, Chang W. Interplay between CaSR and PTH1R signaling in skeletal development and osteoanabolism. Semin Cell Dev Biol. 2016 Jan; 49:11-23. PMID: 26688334.
      View in: PubMed
    6. Bollerslev J, Rejnmark L, Marcocci C, Shoback DM, Sitges-Serra A, van Biesen W, Dekkers OM. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults. Eur J Endocrinol. 2015 Aug; 173(2):G1-20. PMID: 26160136.
      View in: PubMed
    7. Shah AD, Hsiao EC, O'Donnell B, Salmeen K, Nussbaum R, Krebs M, Baumgartner-Parzer S, Kaufmann M, Jones G, Bikle DD, Wang Y, Mathew AS, Shoback D, Block-Kurbisch I. Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. J Clin Endocrinol Metab. 2015 Aug; 100(8):2832-6. PMID: 26097993; PMCID: PMC4524985 [Available on 08/01/16].
    8. Shah AD, Shoback D, Lewiecki EM. Sclerostin inhibition: a novel therapeutic approach in the treatment of osteoporosis. Int J Womens Health. 2015; 7:565-80. PMID: 26082665; PMCID: PMC4459616.
    9. Schafer AL, Weaver CM, Black DM, Wheeler AL, Chang H, Szefc GV, Stewart L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE. Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status. J Bone Miner Res. 2015 Aug; 30(8):1377-85. PMID: 25640580; PMCID: PMC4593653 [Available on 08/01/16].
    10. Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study. Bone. 2015 May; 74:140-5. PMID: 25603463; PMCID: PMC4355193 [Available on 05/01/16].
    11. Lai JC, Shoback DM, Zipperstein J, Lizaola B, Tseng S, Terrault NA. Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C. Dig Dis Sci. 2015 Jun; 60(6):1813-9. PMID: 25563723.
      View in: PubMed
    12. Marcocci C, Bollerslev J, Khan AA, Shoback DM. Medical management of primary hyperparathyroidism: proceedings of the fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism. J Clin Endocrinol Metab. 2014 Oct; 99(10):3607-18. PMID: 25162668.
      View in: PubMed
    13. Eastell R, Brandi ML, Costa AG, D'Amour P, Shoback DM, Thakker RV. Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop. J Clin Endocrinol Metab. 2014 Oct; 99(10):3570-9. PMID: 25162666.
      View in: PubMed
    14. Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. J Bone Miner Res. 2014 Apr; 29(4):911-21. PMID: 24014458; PMCID: PMC4419358.
    15. Canales BK, Schafer AL, Shoback DM, Carpenter TO. Gastric bypass in obese rats causes bone loss, vitamin D deficiency, metabolic acidosis, and elevated peptide YY. Surg Obes Relat Dis. 2014 Sep-Oct; 10(5):878-84. PMID: 24969093; PMCID: PMC4113565.
    16. Hong SH, Dvorak-Ewell M, Stevens HY, Barish GD, Castro GL, Nofsinger R, Frangos JA, Shoback D, Evans RM. Rescue of a primary myelofibrosis model by retinoid-antagonist therapy. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18820-5. PMID: 24191050; PMCID: PMC3839709.
    17. Mannstadt M, Clarke BL, Vokes T, Brandi ML, Ranganath L, Fraser WD, Lakatos P, Bajnok L, Garceau R, Mosekilde L, Lagast H, Shoback D, Bilezikian JP. Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study. Lancet Diabetes Endocrinol. 2013 Dec; 1(4):275-83. PMID: 24622413.
      View in: PubMed
    18. Cheng Z, Liang N, Chen TH, Li A, Santa Maria C, You M, Ho H, Song F, Bikle D, Tu C, Shoback D, Chang W. Sex and age modify biochemical and skeletal manifestations of chronic hyperparathyroidism by altering target organ responses to Ca2+ and parathyroid hormone in mice. J Bone Miner Res. 2013 May; 28(5):1087-100. PMID: 23239173; PMCID: PMC3617088.
    19. Schafer AL, Burghardt AJ, Sellmeyer DE, Palermo L, Shoback DM, Majumdar S, Black DM. Postmenopausal women treated with combination parathyroid hormone (1-84) and ibandronate demonstrate different microstructural changes at the radius vs. tibia: the PTH and Ibandronate Combination Study (PICS). Osteoporos Int. 2013 Oct; 24(10):2591-601. PMID: 23589163.
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    20. Nemeth EF, Shoback D. Calcimimetic and calcilytic drugs for treating bone and mineral-related disorders. Best Pract Res Clin Endocrinol Metab. 2013 Jun; 27(3):373-84. PMID: 23856266.
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    21. Park-Sigal J, Don BR, Porzig A, Recker R, Griswold V, Sebastian A, Duh QY, Portale AA, Shoback D, Schambelan M. Severe hypercalcemic hyperparathyroidism developing in a patient with hyperaldosteronism and renal resistance to parathyroid hormone. J Bone Miner Res. 2013 Mar; 28(3):700-8. PMID: 23074096.
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    22. Schafer AL, Sellmeyer DE, Palermo L, Hietpas J, Eastell R, Shoback DM, Black DM. Six months of parathyroid Hormone (1-84) administered concurrently versus sequentially with monthly ibandronate over two years: the PTH and ibandronate combination study (PICS) randomized trial. J Clin Endocrinol Metab. 2012 Oct; 97(10):3522-9. PMID: 22791766; PMCID: PMC3674294.
    23. Khosla S, Bilezikian JP, Dempster DW, Lewiecki EM, Miller PD, Neer RM, Recker RR, Shane E, Shoback D, Potts JT. Benefits and risks of bisphosphonate therapy for osteoporosis. J Clin Endocrinol Metab. 2012 Jul; 97(7):2272-82. PMID: 22523337.
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    24. Dvorak-Ewell MM, Chen TH, Liang N, Garvey C, Liu B, Tu C, Chang W, Bikle DD, Shoback DM. Osteoblast extracellular Ca2+ -sensing receptor regulates bone development, mineralization, and turnover. J Bone Miner Res. 2011 Dec; 26(12):2935-47. PMID: 21956637; PMCID: PMC3222747.
    25. Prasad AP, George V, Porzig A, Horvai AE, Gross A, Shoback D, Link TM. Progressive craniofacial bone loss after cosmetic surgery at the forehead. Skeletal Radiol. 2012 Apr; 41(4):477-81. PMID: 22127344.
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    26. Schafer AL, Sellmeyer DE, Schwartz AV, Rosen CJ, Vittinghoff E, Palermo L, Bilezikian JP, Shoback DM, Black DM. Change in undercarboxylated osteocalcin is associated with changes in body weight, fat mass, and adiponectin: parathyroid hormone (1-84) or alendronate therapy in postmenopausal women with osteoporosis (the PaTH study). J Clin Endocrinol Metab. 2011 Dec; 96(12):E1982-9. PMID: 21994958; PMCID: PMC3232610.
    27. Bilezikian JP, Khan A, Potts JT, Brandi ML, Clarke BL, Shoback D, Jüppner H, D'Amour P, Fox J, Rejnmark L, Mosekilde L, Rubin MR, Dempster D, Gafni R, Collins MT, Sliney J, Sanders J. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011 Oct; 26(10):2317-37. PMID: 21812031; PMCID: PMC3405491.
    28. Peacock M, Bilezikian JP, Bolognese MA, Borofsky M, Scumpia S, Sterling LR, Cheng S, Shoback D. Cinacalcet HCl reduces hypercalcemia in primary hyperparathyroidism across a wide spectrum of disease severity. J Clin Endocrinol Metab. 2011 Jan; 96(1):E9-18. PMID: 20943783; PMCID: PMC3203649.
    29. Dong Q, Cheng Z, Chang W, Blackman BE, Conte FA, Hu J, Shoback D, Miller WL. Naturally-occurring mutation in the calcium-sensing receptor reveals the significance of extracellular domain loop III region for class C G-protein-coupled receptor function. J Clin Endocrinol Metab. 2010 Oct; 95(10):E245-52. PMID: 20631026; PMCID: PMC3050095.
    30. Chang W, Dvorak M, Shoback D. Assessing constitutive activity of extracellular calcium-sensing receptors in vitro and in bone. Methods Enzymol. 2010; 484:253-66. PMID: 21036236; PMCID: PMC3528079.
    31. Peacock M, Bolognese MA, Borofsky M, Scumpia S, Sterling LR, Cheng S, Shoback D. Cinacalcet treatment of primary hyperparathyroidism: biochemical and bone densitometric outcomes in a five-year study. J Clin Endocrinol Metab. 2009 Dec; 94(12):4860-7. PMID: 19837909.
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    32. Pao VY, Chang S, Shoback DM, Bikle DD. Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review. J Bone Miner Res. 2009 Jun; 24(6):1135-9. PMID: 19113910.
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    33. Marcocci C, Chanson P, Shoback D, Bilezikian J, Fernandez-Cruz L, Orgiazzi J, Henzen C, Cheng S, Sterling LR, Lu J, Peacock M. Cinacalcet reduces serum calcium concentrations in patients with intractable primary hyperparathyroidism. J Clin Endocrinol Metab. 2009 Aug; 94(8):2766-72. PMID: 19470620; PMCID: PMC3214593.
    34. Khan A, Grey A, Shoback D. Medical management of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. J Clin Endocrinol Metab. 2009 Feb; 94(2):373-81. PMID: 19193912.
      View in: PubMed
    35. Chang W, Tu C, Chen TH, Bikle D, Shoback D. The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2008; 1(35):ra1. PMID: 18765830; PMCID: PMC3538864.
    36. Shoback D. Clinical practice. Hypoparathyroidism. N Engl J Med. 2008 Jul 24; 359(4):391-403. PMID: 18650515.
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    37. Silverberg SJ, Rubin MR, Faiman C, Peacock M, Shoback DM, Smallridge RC, Schwanauer LE, Olson KA, Klassen P, Bilezikian JP. Cinacalcet hydrochloride reduces the serum calcium concentration in inoperable parathyroid carcinoma. J Clin Endocrinol Metab. 2007 Oct; 92(10):3803-8. PMID: 17666472.
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    38. Cheng Z, Tu C, Rodriguez L, Chen TH, Dvorak MM, Margeta M, Gassmann M, Bettler B, Shoback D, Chang W. Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology. 2007 Oct; 148(10):4984-92. PMID: 17615148.
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    39. Chang W, Tu C, Cheng Z, Rodriguez L, Chen TH, Gassmann M, Bettler B, Margeta M, Jan LY, Shoback D. Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. J Biol Chem. 2007 Aug 24; 282(34):25030-40. PMID: 17591780.
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    40. Dvorak MM, Chen TH, Orwoll B, Garvey C, Chang W, Bikle DD, Shoback DM. Constitutive activity of the osteoblast Ca2+-sensing receptor promotes loss of cancellous bone. Endocrinology. 2007 Jul; 148(7):3156-63. PMID: 17412806.
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    41. Shoback D. Update in osteoporosis and metabolic bone disorders. J Clin Endocrinol Metab. 2007 Mar; 92(3):747-53. PMID: 17341572.
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    42. Rodriguez L, Tu C, Cheng Z, Chen TH, Bikle D, Shoback D, Chang W. Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes. Endocrinology. 2005 Dec; 146(12):5294-303. PMID: 16166224.
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    43. Chang W, Rodriguez L, Chen TH, Tu C, Shoback D. Extracellular Ca2+-sensing in cartilage. J Musculoskelet Neuronal Interact. 2004 Dec; 4(4):410-1. PMID: 15758285.
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    44. Peacock M, Bilezikian JP, Klassen PS, Guo MD, Turner SA, Shoback D. Cinacalcet hydrochloride maintains long-term normocalcemia in patients with primary hyperparathyroidism. J Clin Endocrinol Metab. 2005 Jan; 90(1):135-41. PMID: 15522938.
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    45. Loretz CA, Pollina C, Hyodo S, Takei Y, Chang W, Shoback D. cDNA cloning and functional expression of a Ca2+-sensing receptor with truncated C-terminal tail from the Mozambique tilapia (Oreochromis mossambicus). J Biol Chem. 2004 Dec 17; 279(51):53288-97. PMID: 15456780.
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    46. Earle KE, Seneviratne T, Shaker J, Shoback D. Fanconi's syndrome in HIV+ adults: report of three cases and literature review. J Bone Miner Res. 2004 May; 19(5):714-21. PMID: 15068493.
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    47. Chang W, Shoback D. Extracellular Ca2+-sensing receptors--an overview. Cell Calcium. 2004 Mar; 35(3):183-96. PMID: 15200142.
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    48. Shoback DM, Bilezikian JP, Turner SA, McCary LC, Guo MD, Peacock M. The calcimimetic cinacalcet normalizes serum calcium in subjects with primary hyperparathyroidism. J Clin Endocrinol Metab. 2003 Dec; 88(12):5644-9. PMID: 14671147.
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    49. Shattuck TM, Välimäki S, Obara T, Gaz RD, Clark OH, Shoback D, Wierman ME, Tojo K, Robbins CM, Carpten JD, Farnebo LO, Larsson C, Arnold A. Somatic and germ-line mutations of the HRPT2 gene in sporadic parathyroid carcinoma. N Engl J Med. 2003 Oct 30; 349(18):1722-9. PMID: 14585940.
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    50. Shattuck TM, Kim TS, Costa J, Yandell DW, Imanishi Y, Palanisamy N, Gaz RD, Shoback D, Clark OH, Monchik JM, Wierman ME, Hollenberg A, Tojo K, Chaganti RS, Arnold A. Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in parathyroid carcinoma. Clin Endocrinol (Oxf). 2003 Aug; 59(2):180-9. PMID: 12864795.
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    51. Antoniucci DM, Shoback D. Calcimimetics in the treatment of primary hyperparathyroidism. J Bone Miner Res. 2002 Nov; 17 Suppl 2:N141-5. PMID: 12412791.
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    52. Chang W, Tu C, Pratt S, Chen TH, Shoback D. Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells. Endocrinology. 2002 Apr; 143(4):1467-74. PMID: 11897705.
      View in: PubMed
    53. Chang W, Pratt S, Chen TH, Bourguignon L, Shoback D. Amino acids in the cytoplasmic C terminus of the parathyroid Ca2+-sensing receptor mediate efficient cell-surface expression and phospholipase C activation. J Biol Chem. 2001 Nov 23; 276(47):44129-36. PMID: 11535593.
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    54. Shoback D, Chang W. Starvation amidst plenty--rickets and hypercalcemia in calcium receptor knockout mice. Endocrinology. 2001 Sep; 142(9):3733-5. PMID: 11517147.
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    55. Chang W, Pratt SA, Chen TH, Tu CL, Mikala G, Schwartz A, Shoback D. Parathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits. Am J Physiol Endocrinol Metab. 2001 Jul; 281(1):E180-9. PMID: 11404236.
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    56. Imboden JB, Shoback DM, Inokuchi S. Analysis of inositol phospholipid turnover during lymphocyte activation. Curr Protoc Immunol. 2001 May; Chapter 11:Unit 11.1. PMID: 18432702.
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    57. Chang W, Chen TH, Pratt S, Shoback D. Amino acids in the second and third intracellular loops of the parathyroid Ca2+-sensing receptor mediate efficient coupling to phospholipase C. J Biol Chem. 2000 Jun 30; 275(26):19955-63. PMID: 10764812.
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    58. Noor M, Shoback D. Paget's disease of bone: diagnosis and treatment update. Curr Rheumatol Rep. 2000 Feb; 2(1):67-73. PMID: 11123042.
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    59. Chang W, Pratt S, Chen TH, Shoback D. Protein kinase C activation blocks calcium receptor signaling in Xenopus laevis oocytes. Mol Cell Endocrinol. 1999 Dec 20; 158(1-2):13-23. PMID: 10630401.
      View in: PubMed
    60. Chang W, Tu C, Chen TH, Komuves L, Oda Y, Pratt SA, Miller S, Shoback D. Expression and signal transduction of calcium-sensing receptors in cartilage and bone. Endocrinology. 1999 Dec; 140(12):5883-93. PMID: 10579354.
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    61. Chang W, Tu C, Bajra R, Komuves L, Miller S, Strewler G, Shoback D. Calcium sensing in cultured chondrogenic RCJ3.1C5.18 cells. Endocrinology. 1999 Apr; 140(4):1911-9. PMID: 10098531.
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    62. Khovidhunkit W, Shoback DM. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999 Mar 2; 130(5):431-9. PMID: 10068418.
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    63. Chang W, Chen TH, Pratt S, Shoback D. Regulation of extracellular calcium-activated cation currents by cAMP in parathyroid cells. Am J Physiol. 1998 Aug; 275(2 Pt 1):E213-21. PMID: 9688621.
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    64. Loh KC, Duh QY, Shoback D, Gee L, Siperstein A, Clark OH. Clinical profile of primary hyperparathyroidism in adolescents and young adults. Clin Endocrinol (Oxf). 1998 Apr; 48(4):435-43. PMID: 9640410.
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    65. Chang W, Pratt S, Chen TH, Nemeth E, Huang Z, Shoback D. Coupling of calcium receptors to inositol phosphate and cyclic AMP generation in mammalian cells and Xenopus laevis oocytes and immunodetection of receptor protein by region-specific antipeptide antisera. J Bone Miner Res. 1998 Apr; 13(4):570-80. PMID: 9556057.
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    66. Loh K, Matthay KK, Hoover M, Bracho FA, Cortez AB, Conte FA, Albanese CT, Miller TR, Price DC, Flores AJ, Kaviani A, Shoback D. Hypercalcemia in malignant paraganglioma due to parathyroid hormone-related protein. Horm Res. 1998; 50(4):217-21. PMID: 9838243.
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    67. Chang W, Chen TH, Pratt SA, Yen B, Fu M, Shoback D. Parathyroid Ca(2+)-conducting currents are modulated by muscarinic receptor agonists and antagonists. Am J Physiol. 1997 Nov; 273(5 Pt 1):E880-90. PMID: 9374672.
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    68. Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Nissenson RA, Shoback DM. The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways. J Biol Chem. 1996 Dec 27; 271(52):33382-9. PMID: 8969199.
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    69. Chang W, Chen TH, Gardner P, Shoback D. Regulation of Ca(2+)-conducting currents in parathyroid cells by extracellular Ca(2+) and channel blockers. Am J Physiol. 1995 Nov; 269(5 Pt 1):E864-77. PMID: 7491938.
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    70. Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Shoback DM, Nissenson RA. Mutational analysis of the cytoplasmic tail of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein: effects on receptor expression and signaling. Mol Endocrinol. 1995 Sep; 9(9):1240-9. PMID: 7491116.
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    71. Funk JL, Shoback DM, Genant HK. Transient osteoporosis of the hip in pregnancy: natural history of changes in bone mineral density. Clin Endocrinol (Oxf). 1995 Sep; 43(3):373-82. PMID: 7586609.
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    72. Shoback D, Chen TH, Pratt S, Lattyak B. Thapsigargin stimulates intracellular calcium mobilization and inhibits parathyroid hormone release. J Bone Miner Res. 1995 May; 10(5):743-50. PMID: 7639110.
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    73. Chen TH, Pratt SA, Shoback DM. Injection of bovine parathyroid poly(A)+ RNA into Xenopus oocytes confers sensitivity to high extracellular calcium. J Bone Miner Res. 1994 Feb; 9(2):293-300. PMID: 7511319.
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    74. Shoback DM, Chen TH, Lattyak B, King K, Johnson RM. Effects of high extracellular calcium and strontium on inositol polyphosphates in bovine parathyroid cells. J Bone Miner Res. 1993 Jul; 8(7):891-8. PMID: 8352071.
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    75. Nissenson RA, Huang Z, Blind E, Shoback D. Structure and function of the receptor for parathyroid hormone and parathyroid hormone-related protein. Receptor. 1993; 3(3):193-202. PMID: 8167570.
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    76. Shoback D, Chen TH. Effects of protein kinase C activation on inositol phosphate generation and intracellular Ca2+ mobilization in bovine parathyroid cells. Endocrinology. 1990 Jul; 127(1):141-8. PMID: 2361470.
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    77. McGhee JG, Shoback D. Effects of phosphatidic acid on parathyroid hormone release, intracellular free Ca2+, and inositol phosphates in dispersed bovine parathyroid cells. Endocrinology. 1990 Feb; 126(2):899-907. PMID: 2153532.
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    78. Membreño L, Chen TH, Woodley S, Gagucas R, Shoback D. The effects of protein kinase-C agonists on parathyroid hormone release and intracellular free Ca2+ in bovine parathyroid cells. Endocrinology. 1989 Feb; 124(2):789-97. PMID: 2536321.
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    79. Shoback DM, Membreno LA, McGhee JG. High calcium and other divalent cations increase inositol trisphosphate in bovine parathyroid cells. Endocrinology. 1988 Jul; 123(1):382-9. PMID: 3260174.
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    80. Shoback DM, McGhee JM. Fluoride stimulates the accumulation of inositol phosphates, increases intracellular free calcium, and inhibits parathyroid hormone release in dispersed bovine parathyroid cells. Endocrinology. 1988 Jun; 122(6):2833-9. PMID: 2836175.
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    81. Gavin LA, Moeller M, Shoback D, Cavalieri RR. Reverse T3 and modulators of the calcium messenger system rapidly decrease T4-5'-deiodinase II activity in cultured mouse neuroblastoma cells. Thyroidology. 1988 Apr; (1):5-12. PMID: 2484895.
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    82. Rabinowe SL, Redgrave JE, Shoback DM, Podolsky S, Hollenberg NK, Williams GH. Renin suppression by saline is blunted in nonmodulating essential hypertension. Hypertension. 1987 Oct; 10(4):404-8. PMID: 3308701.
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    83. Brown EM, Watson EJ, Thatcher JG, Koletsky R, Dawson-Hughes BF, Posillico JT, Shoback D. Ouabain and low extracellular potassium inhibit PTH secretion from bovine parathyroid cells by a mechanism that does not involve increases in the cytosolic calcium concentration. Metabolism. 1987 Jan; 36(1):36-42. PMID: 3025550.
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    84. Hollenberg NK, Moore T, Shoback D, Redgrave J, Rabinowe S, Williams GH. Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. Am J Med. 1986 Sep; 81(3):412-8. PMID: 3752141.
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    85. Imboden JB, Shoback D, Pattison G, Stobo JD. Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphosphate and cytoplasmic free calcium. Proc Natl Acad Sci U S A. 1986 Aug; 83(15):5673-7. PMID: 3016713; PMCID: PMC386351.
    86. LeBoff MS, Shoback D, Brown EM, Thatcher J, Leombruno R, Beaudoin D, Henry M, Wilson R, Pallotta J, Marynick S. Regulation of parathyroid hormone release and cytosolic calcium by extracellular calcium in dispersed and cultured bovine and pathological human parathyroid cells. J Clin Invest. 1985 Jan; 75(1):49-57. PMID: 3965511; PMCID: PMC423397.
    87. Shoback DM, Thatcher JG, Brown EM. Interaction of extracellular calcium and magnesium in the regulation of cytosolic calcium and PTH release in dispersed bovine parathyroid cells. Mol Cell Endocrinol. 1984 Dec; 38(2-3):179-86. PMID: 6510551.
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    88. Shoback DM, Brown EM. PTH release stimulated by high extracellular potassium is associated with a decrease in cytosolic calcium in bovine parathyroid cells. Biochem Biophys Res Commun. 1984 Sep 17; 123(2):684-90. PMID: 6487306.
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    89. Weiss A, Imboden J, Shoback D, Stobo J. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A. 1984 Jul; 81(13):4169-73. PMID: 6234599; PMCID: PMC345390.
    90. Shoback DM, Brown EM. Forskolin increases cellular cyclic adenosine monophosphate content and parathyroid hormone release in dispersed bovine parathyroid cells. Metabolism. 1984 Jun; 33(6):509-14. PMID: 6328173.
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    91. Shoback DM, Thatcher J, Leombruno R, Brown EM. Relationship between parathyroid hormone secretion and cytosolic calcium concentration in dispersed bovine parathyroid cells. Proc Natl Acad Sci U S A. 1984 May; 81(10):3113-7. PMID: 6328497; PMCID: PMC345231.
    92. Brown EM, Shoback DM. The relationship between PTH secretion and cytosolic calcium concentration in bovine parathyroid cells. Prog Clin Biol Res. 1984; 168:139-44. PMID: 6096881.
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    93. Shoback DM, Williams GH, Moore TJ, Dluhy RG, Podolsky S, Hollenberg NK. Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension. J Clin Invest. 1983 Dec; 72(6):2115-24. PMID: 6358261; PMCID: PMC437052.
    94. Shoback DM, Williams GH, Swartz SL, Davies RO, Hollenberg NK. Time course and effect of sodium intake on vascular and hormonal responses to enalapril (MK 421) in normal subjects. J Cardiovasc Pharmacol. 1983 Nov-Dec; 5(6):1010-8. PMID: 6196548.
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    95. Shoback DM, Williams GH, Hollenberg NK, Davies RO, Moore TJ, Dluhy RG. Endogenous angiotensin II as a determinant of sodium-modulated changes in tissue responsiveness to angiotensin II in normal man. J Clin Endocrinol Metab. 1983 Oct; 57(4):764-70. PMID: 6309884.
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    96. Serfas D, Shoback DM, Lorell BH. Phaeochromocytoma and hypertrophic cardiomyopathy: apparent suppression of symptoms and noradrenaline secretion by calcium-channel blockade. Lancet. 1983 Sep 24; 2(8352):711-3. PMID: 6136843.
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    97. Shoback D, Thatcher J, Leombruno R, Brown E. Effects of extracellular Ca++ and Mg++ on cytosolic Ca++ and PTH release in dispersed bovine parathyroid cells. Endocrinology. 1983 Jul; 113(1):424-6. PMID: 6861713.
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    98. Vlay SC, Blumenthal DS, Shoback D, Fehir K, Bulkley BH. Delayed acute myocardial infarction after blunt chest trauma in a young woman. Am Heart J. 1980 Dec; 100(6 Pt 1):907-16. PMID: 7446393.
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    99. Shoback D. Familial cryoglobulinemia. Johns Hopkins Med J. 1977 May; 140(5):267-74. PMID: 859235.
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    100. Shoback D, Kan JA. Clinical-pathological conference. Johns Hopkins Med J. 1977 Apr; 140(4):193-205. PMID: 850338.
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    101. Shoback D. Pheochromocytoma. Johns Hopkins Med J. 1976 Sep; 139(3):131-7. PMID: 972438.
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