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    Elvin Geng

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentMedicine
    AddressSFGH Bldg 80, WD 86
    Phone415-476-4082x409

       Overview 
       Overview
      I am currently Assistant Adjunct Professor of Medicine at the University of California at San Francisco (UCSF). I trained in infectious diseases (MD, Columbia 2002) and epidemiology (MPH, Columbia 2002). My research seeks to apply perspectives from implementation and dissemination sciences to understand the effectiveness of global antiretroviral treatment (ART) programs for HIV-infected patients. Currently, the Global Fund, US President’s Emergency Fund for AIDS Relief (PEPFAR) and national governments have invested billions of dollars for AIDS programs and started five million persons on ART in resource limited settings. Yet the best strategies for engagement in care and treatment with life-long, complicated and potentially toxic medications include many unanswered questions. For patients who present to care, failure to initiate ART is underappreciated and a major barrier that is poorly understood. Once on ART, early mortality – likely to due to unascertained opportunistic infections – is high and the causes incompletely understood. Among patients who stabilize on ART, loss to follow-up is ubiquitous in African ART programs. To address these problems I am involved in a number of studies including (1) assembly of a cohort of HIV-infected patients in southwestern Uganda as part of an NIH funded consortium in East Africa; (2) a nested case control study to identify causes of early mortality in Uganda; (3) extending novel methods into the cohort setting to study engagement in care and (4) and using causal methods to understand longitudinal treatment effects in data collected in these settings. Overall, I hope to bring clinical contextual knowledge to bear on analysis of data from “real world” settings to improve the effectiveness of global ART implementation. Furthermore, I hope this research can yield generalizable lessons for science of implementation in health care that may be of use in other settings and other disease conditions.

       Interests
      Implementation Science, Socioeconomically marginalized groups, Clinic, Hospital, International (public health), International (medical), Practice guidelines, hiv, tuberculosis, Brief implementation science training courses

       ORNG Applications 
       Websites
       In The News
       Awarded Grants
       Global Health
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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Edwards JK, Cole SR, Westreich D, Moore R, Mathews C, Geng E, Eron JJ, Mugavero MJ. Loss to Clinic and Five-Year Mortality among HIV-Infected Antiretroviral Therapy Initiators. PLoS One. 2014; 9(7):e102305.
        View in: PubMed
      2. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. The authors reply. Am J Epidemiol. 2014 Aug 15; 180(4):450.
        View in: PubMed
      3. Kim HN, Rodriguez CV, Van Rompaey S, Eron JJ, Thio CL, Crane HM, Overton ET, Saag MS, Martin J, Geng E, Mugavero M, Rodriguez B, Mathews WC, Boswell S, Moore R, Kitahata MM. Factors Associated With Delayed Hepatitis B Viral Suppression on Tenofovir Among Patients Coinfected With HBV-HIV in the CNICS Cohort. J Acquir Immune Defic Syndr. 2014 May 1; 66(1):96-101.
        View in: PubMed
      4. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. Lessons Learned From the Design and Implementation of Myocardial Infarction Adjudication Tailored for HIV Clinical Cohorts. Am J Epidemiol. 2014 Apr 15; 179(8):996-1005.
        View in: PubMed
      5. Jain V, Byonanebye DM, Liegler T, Kwarisiima D, Chamie G, Kabami J, Petersen ML, Balzer LB, Clark TD, Black D, Thirumurthy H, Geng EH, Charlebois ED, Amanyire G, Kamya MR, Havlir DV. Changes in Population HIV RNA Levels in Mbarara, Uganda, During Scale-up of HIV Antiretroviral Therapy Access. J Acquir Immune Defic Syndr. 2014 Mar 1; 65(3):327-32.
        View in: PubMed
      6. Kotwani P, Balzer L, Kwarisiima D, Clark TD, Kabami J, Byonanebye D, Bainomujuni B, Black D, Chamie G, Jain V, Thirumurthy H, Kamya MR, Geng EH, Petersen ML, Havlir DV, Charlebois ED. Evaluating linkage to care for hypertension after community-based screening in rural Uganda. Trop Med Int Health. 2014 Apr; 19(4):459-68.
        View in: PubMed
      7. Chamie G, Kwarisiima D, Clark TD, Kabami J, Jain V, Geng E, Balzer LB, Petersen ML, Thirumurthy H, Charlebois ED, Kamya MR, Havlir DV. Uptake of Community-Based HIV Testing during a Multi-Disease Health Campaign in Rural Uganda. PLoS One. 2014; 9(1):e84317.
        View in: PubMed
      8. Kotwani P, Kwarisiima D, Clark TD, Kabami J, Geng EH, Jain V, Chamie G, Petersen ML, Thirumurthy H, Kamya MR, Charlebois ED, Havlir DV. Epidemiology and awareness of hypertension in a rural Ugandan community: a cross-sectional study. BMC Public Health. 2013; 13(1):1151.
        View in: PubMed
      9. Vijayan T, Semitala FC, Matsiko N, Elyanu P, Namusobya J, Havlir DV, Kamya M, Geng EH. Changes in the Timing of Antiretroviral Therapy Initiation in HIV-Infected Patients With Tuberculosis in Uganda: A Study of the Diffusion of Evidence Into Practice in the Global Response to HIV/AIDS. Clin Infect Dis. 2013 Dec; 57(12):1766-72.
        View in: PubMed
      10. Namusobya J, Semitala FC, Amanyire G, Kabami J, Chamie G, Bogere J, Jain V, Clark TD, Charlebois E, Havlir DV, Kamya M, Geng EH. High retention in care among HIV-infected patients entering care with CD4 levels >350 cells/µL under routine program conditions in Uganda. Clin Infect Dis. 2013 Nov; 57(9):1343-50.
        View in: PubMed
      11. Geng EH, Bwana MB, Muyindike W, Glidden DV, Bangsberg DR, Neilands TB, Bernheimer I, Musinguzi N, Yiannoutsos CT, Martin JN. Failure to initiate antiretroviral therapy, loss to follow-up and mortality among HIV-infected patients during the pre-ART period in Uganda. J Acquir Immune Defic Syndr. 2013 Jun 1; 63(2):e64-71.
        View in: PubMed
      12. Christopoulos KA, Massey AD, Lopez AM, Geng EH, Johnson MO, Pilcher CD, Fielding H, Dawson-Rose C. "Taking a half day at a time:" patient perspectives and the HIV engagement in care continuum. AIDS Patient Care STDS. 2013 Apr; 27(4):223-30.
        View in: PubMed
      13. Thirumurthy H, Chamie G, Jain V, Kabami J, Kwarisiima D, Clark TD, Geng E, Petersen ML, Charlebois ED, Kamya MR, Havlir DV. Improved employment and education outcomes in households of HIV-infected adults with high CD4 cell counts: evidence from a community health campaign in Uganda. AIDS. 2013 Feb 20; 27(4):627-34.
        View in: PubMed
      14. Ware NC, Wyatt MA, Geng EH, Kaaya SF, Agbaji OO, Muyindike WR, Chalamilla G, Agaba PA. Toward an understanding of disengagement from HIV treatment and care in sub-Saharan Africa: a qualitative study. PLoS Med. 2013; 10(1):e1001369; discussion e1001369.
        View in: PubMed
      15. Jain V, Liegler T, Kabami J, Chamie G, Clark TD, Black D, Geng EH, Kwarisiima D, Wong JK, Abdel-Mohsen M, Sonawane N, Aweeka FT, Thirumurthy H, Petersen ML, Charlebois ED, Kamya MR, Havlir DV. Assessment of population-based HIV RNA levels in a rural east African setting using a fingerprick-based blood collection method. Clin Infect Dis. 2013 Feb; 56(4):598-605.
        View in: PubMed
      16. Geng EH, Hare CB, Kahn JO, Jain V, Van Nunnery T, Christopoulos KA, Deeks SG, Gandhi M, Havlir DV. The effect of a "universal antiretroviral therapy" recommendation on HIV RNA levels among HIV-infected patients entering care with a CD4 count greater than 500/µL in a public health setting. Clin Infect Dis. 2012 Dec; 55(12):1690-7.
        View in: PubMed
      17. Chamie G, Kwarisiima D, Clark TD, Kabami J, Jain V, Geng E, Petersen ML, Thirumurthy H, Kamya MR, Havlir DV, Charlebois ED. Leveraging rapid community-based HIV testing campaigns for non-communicable diseases in rural Uganda. PLoS One. 2012; 7(8):e43400.
        View in: PubMed
      18. Siedner MJ, Lankowski A, Haberer JE, Kembabazi A, Emenyonu N, Tsai AC, Muzoora C, Geng E, Martin JN, Bangsberg DR. Rethinking the "pre" in pre-therapy counseling: no benefit of additional visits prior to therapy on adherence or viremia in Ugandans initiating ARVs. PLoS One. 2012; 7(6):e39894.
        View in: PubMed
      19. Lamb MR, El-Sadr WM, Geng E, Nash D. Association of adherence support and outreach services with total attrition, loss to follow-up, and death among ART patients in sub-Saharan Africa. PLoS One. 2012; 7(6):e38443.
        View in: PubMed
      20. Jordan MR, Bennett DE, Wainberg MA, Havlir D, Hammer S, Yang C, Morris L, Peeters M, Wensing AM, Parkin N, Nachega JB, Phillips A, De Luca A, Geng E, Calmy A, Raizes E, Sandstrom P, Archibald CP, Perriëns J, McClure CM, Hong SY, McMahon JH, Dedes N, Sutherland D, Bertagnolio S. Update on World Health Organization HIV drug resistance prevention and assessment strategy: 2004-2011. Clin Infect Dis. 2012 May; 54 Suppl 4:S245-9.
        View in: PubMed
      21. Geng EH, Glidden DV, Bangsberg DR, Bwana MB, Musinguzi N, Nash D, Metcalfe JZ, Yiannoutsos CT, Martin JN, Petersen ML. A causal framework for understanding the effect of losses to follow-up on epidemiologic analyses in clinic-based cohorts: the case of HIV-infected patients on antiretroviral therapy in Africa. Am J Epidemiol. 2012 May 15; 175(10):1080-7.
        View in: PubMed
      22. Geng EH, Kahn JS, Chang OC, Hare CB, Christopoulos KA, Jones D, Petersen ML, Deeks SG, Havlir DV, Gandhi M. The effect of AIDS Clinical Trials Group Protocol 5164 on the time from Pneumocystis jirovecii pneumonia diagnosis to antiretroviral initiation in routine clinical practice: a case study of diffusion, dissemination, and implementation. Clin Infect Dis. 2011 Nov; 53(10):1008-14.
        View in: PubMed
      23. Geng EH, Hunt PW, Diero LO, Kimaiyo S, Somi GR, Okong P, Bangsberg DR, Bwana MB, Cohen CR, Otieno JA, Wabwire D, Elul B, Nash D, Easterbrook PJ, Braitstein P, Musick BS, Martin JN, Yiannoutsos CT, Wools-Kaloustian K. Trends in the clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009. J Int AIDS Soc. 2011; 14:46.
        View in: PubMed
      24. Dowdy DW, Geng EH, Christopoulos KA, Kahn JS, Hare CB, Wlodarczyk D, Havlir DV. Mortality among antiretroviral-eligible patients in an urban public clinic. J Acquir Immune Defic Syndr. 2011 Aug 1; 57(4):297-300.
        View in: PubMed
      25. Geng EH, Glidden DV, Bwana MB, Musinguzi N, Emenyonu N, Muyindike W, Christopoulos KA, Neilands TB, Yiannoutsos CT, Deeks SG, Bangsberg DR, Martin JN. Retention in care and connection to care among HIV-infected patients on antiretroviral therapy in Africa: estimation via a sampling-based approach. PLoS One. 2011; 6(7):e21797.
        View in: PubMed
      26. Egger M, Spycher BD, Sidle J, Weigel R, Geng EH, Fox MP, MacPhail P, van Cutsem G, Messou E, Wood R, Nash D, Pascoe M, Dickinson D, Etard JF, McIntyre JA, Brinkhof MW. Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa. PLoS Med. 2011; 8(1):e1000390.
        View in: PubMed
      27. Geng EH, Bwana MB, Kabakyenga J, Muyindike W, Emenyonu NI, Musinguzi N, Mugyenyi P, Martin JN, Bangsberg DR. Diminishing availability of publicly funded slots for antiretroviral initiation among HIV-infected ART-eligible patients in Uganda. PLoS One. 2010; 5(11):e14098.
        View in: PubMed
      28. Geng EH, Nash D, Kambugu A, Zhang Y, Braitstein P, Christopoulos KA, Muyindike W, Bwana MB, Yiannoutsos CT, Petersen ML, Martin JN. Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions. Curr HIV/AIDS Rep. 2010 Nov; 7(4):234-44.
        View in: PubMed
      29. Geng EH, Glidden DV, Emenyonu N, Musinguzi N, Bwana MB, Neilands TB, Muyindike W, Yiannoutsos CT, Deeks SG, Bangsberg DR, Martin JN. Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in Africa. Trop Med Int Health. 2010 Jun; 15 Suppl 1:63-9.
        View in: PubMed
      30. Geng EH, Bangsberg DR, Musinguzi N, Emenyonu N, Bwana MB, Yiannoutsos CT, Glidden DV, Deeks SG, Martin JN. Understanding reasons for and outcomes of patients lost to follow-up in antiretroviral therapy programs in Africa through a sampling-based approach. J Acquir Immune Defic Syndr. 2010 Mar; 53(3):405-11.
        View in: PubMed
      31. Zhou Z, Meyers K, Li X, Chen Q, Qian H, Lao Y, Geng E, Fan Y, Yang S, Chiu M, Ho DD. Prevention of mother-to-child transmission of HIV-1 using highly active antiretroviral therapy in rural Yunnan, China. J Acquir Immune Defic Syndr. 2010 Feb; 53 Suppl 1:S15-22.
        View in: PubMed
      32. Kigozi IM, Dobkin LM, Martin JN, Geng EH, Muyindike W, Emenyonu NI, Bangsberg DR, Hahn JA. Late-disease stage at presentation to an HIV clinic in the era of free antiretroviral therapy in Sub-Saharan Africa. J Acquir Immune Defic Syndr. 2009 Oct 1; 52(2):280-9.
        View in: PubMed
      33. Geng EH, Deeks SG. CD4+ T cell recovery with antiretroviral therapy: more than the sum of the parts. Clin Infect Dis. 2009 Feb 1; 48(3):362-4.
        View in: PubMed
      34. Geng EH, Emenyonu N, Bwana MB, Glidden DV, Martin JN. Sampling-based approach to determining outcomes of patients lost to follow-up in antiretroviral therapy scale-up programs in Africa. JAMA. 2008 Aug 6; 300(5):506-7.
        View in: PubMed
      35. Tabaee A, Geng E, Lin J, Kakoullis S, McDonald B, Rodriguez H, Chong D. Impact of neck length on the safety of percutaneous and surgical tracheotomy: a prospective, randomized study. Laryngoscope. 2005 Sep; 115(9):1685-90.
        View in: PubMed
      36. Geng E, Kreiswirth B, Burzynski J, Schluger NW. Clinical and radiographic correlates of primary and reactivation tuberculosis: a molecular epidemiology study. JAMA. 2005 Jun 8; 293(22):2740-5.
        View in: PubMed
      37. Geng EH, Kreiswirth BN, Burzynski J, Schluger NW. Transmission trends for human immunodeficiency virus associated tuberculosis in New York City. Int J Tuberc Lung Dis. 2005 Jun; 9(6):661-6.
        View in: PubMed
      38. Geng E, Kreiswirth B, Driver C, Li J, Burzynski J, DellaLatta P, LaPaz A, Schluger NW. Changes in the transmission of tuberculosis in New York City from 1990 to 1999. N Engl J Med. 2002 May 9; 346(19):1453-8.
        View in: PubMed
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