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    Emma Lefrancais, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentMedicine
    Address513 Parnassus Ave
    San Francisco CA 94143
    Phone415-476-9190
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Lefrançais E, Duval A, Mirey E, Roga S, Espinosa E, Cayrol C, Girard JP. Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15502-7. PMID: 25313073; PMCID: PMC4217470.
      2. Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 2013 Dec; 62(12):1714-23. PMID: 23172891; PMCID: PMC3841767.
      3. Lefrançais E, Cayrol C. Mechanisms of IL-33 processing and secretion: differences and similarities between IL-1 family members. Eur Cytokine Netw. 2012 Oct-Dec; 23(4):120-7. PMID: 23306193.
        View in: PubMed
      4. Pichery M, Mirey E, Mercier P, Lefrancais E, Dujardin A, Ortega N, Girard JP. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33-LacZ gene trap reporter strain. J Immunol. 2012 Apr 1; 188(7):3488-95. PMID: 22371395.
        View in: PubMed
      5. Lefrançais E, Roga S, Gautier V, Gonzalez-de-Peredo A, Monsarrat B, Girard JP, Cayrol C. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1673-8. PMID: 22307629; PMCID: PMC3277172.
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