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    Francesco Boin, MD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    Address513 Parnassus Ave, Med Sci
    San Francisco CA 94122
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      Collapse Biography 
      Collapse Education and Training
      University of PaduaM.D.School of Medicine1993
      Mayo Clinic Internal MedicineSchool of Medicine2003
      Johns Hopkins UniversityFellowshipRheumatology

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Fava A, Cimbro R, Wigley FM, Liu QR, Rosen A, Boin F. Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma. Arthritis Res Ther. 2016; 18(1):99. PMID: 27145754.
        View in: PubMed
      2. Park JK, Fava A, Carrino J, Del Grande F, Rosen A, Boin F. Association of Acroosteolysis With Enhanced Osteoclastogenesis and Higher Blood Levels of Vascular Endothelial Growth Factor in Systemic Sclerosis. Arthritis Rheumatol. 2016 Jan; 68(1):201-9. PMID: 26361270.
        View in: PubMed
      3. Paik JJ, Wigley FM, Lloyd TE, Corse AM, Casciola-Rosen L, Shah AA, Boin F, Hummers LK, Mammen AL. Spectrum of Muscle Histopathologic Findings in Forty-Two Scleroderma Patients With Weakness. Arthritis Care Res (Hoboken). 2015 Oct; 67(10):1416-25. PMID: 25989455; PMCID: PMC4580502 [Available on 10/01/16].
      4. Huang H, Fava A, Guhr T, Cimbro R, Rosen A, Boin F, Ellis H. A methodology for exploring biomarker--phenotype associations: application to flow cytometry data and systemic sclerosis clinical manifestations. BMC Bioinformatics. 2015; 16:293. PMID: 26373409; PMCID: PMC4571079.
      5. Chizzolini C, Boin F. The role of the acquired immune response in systemic sclerosis. Semin Immunopathol. 2015 Sep; 37(5):519-28. PMID: 26152639.
        View in: PubMed
      6. Poelman CL, Hummers LK, Wigley FM, Anderson C, Boin F, Shah AA. Intravenous immunoglobulin may be an effective therapy for refractory, active diffuse cutaneous systemic sclerosis. J Rheumatol. 2015 Feb; 42(2):236-42. PMID: 25433527; PMCID: PMC4314512 [Available on 02/01/16].
      7. Boin F, Erre GL, Posadino AM, Cossu A, Giordo R, Spinetti G, Passiu G, Emanueli C, Pintus G. Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension. Orphanet J Rare Dis. 2014; 9:123. PMID: 25085432; PMCID: PMC4237898.
      8. Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science. 2014 Jan 10; 343(6167):152-7. PMID: 24310608; PMCID: PMC4038033.
      9. Gelber AC, Manno RL, Shah AA, Woods A, Le EN, Boin F, Hummers LK, Wigley FM. Race and association with disease manifestations and mortality in scleroderma: a 20-year experience at the Johns Hopkins Scleroderma Center and review of the literature. Medicine (Baltimore). 2013 Jul; 92(4):191-205. PMID: 23793108; PMCID: PMC4553970.
      10. Cottrell TR, Wise RA, Wigley FM, Boin F. The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis. Ann Rheum Dis. 2014 Jun; 73(6):1060-6. PMID: 23606705.
        View in: PubMed
      11. Shah AA, Schiopu E, Hummers LK, Wade M, Phillips K, Anderson C, Wise R, Boin F, Seibold JR, Wigley F, Rollins KD. Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion. Arthritis Res Ther. 2013; 15(2):R54. PMID: 23597147.
        View in: PubMed
      12. Fava A, Wung PK, Wigley FM, Hummers LK, Daya NR, Ghazarian SR, Boin F. Efficacy of Rho kinase inhibitor fasudil in secondary Raynaud's phenomenon. Arthritis Care Res (Hoboken). 2012 Jun; 64(6):925-9. PMID: 22275160; PMCID: PMC3343172.
      13. Grader-Beck T, Boin F, von Gunten S, Smith D, Rosen A, Bochner BS. Antibodies recognising sulfated carbohydrates are prevalent in systemic sclerosis and associated with pulmonary vascular disease. Ann Rheum Dis. 2011 Dec; 70(12):2218-24. PMID: 21873333; PMCID: PMC3409247.
      14. Le EN, Wigley FM, Shah AA, Boin F, Hummers LK. Long-term experience of mycophenolate mofetil for treatment of diffuse cutaneous systemic sclerosis. Ann Rheum Dis. 2011 Jun; 70(6):1104-7. PMID: 21378404; PMCID: PMC3828653.
      15. Manno R, Boin F. Immunotherapy of systemic sclerosis. Immunotherapy. 2010 Nov; 2(6):863-78. PMID: 21091117; PMCID: PMC3059511.
      16. Sherber NS, Boin F, Hummers LK, Wigley FM. The "tank top sign": a unique pattern of skin fibrosis seen in pansclerotic morphea. Ann Rheum Dis. 2009 Sep; 68(9):1511-2. PMID: 19674989.
        View in: PubMed
      17. Song P, Gocke C, Wigley FM, Boin F. Resolution of pansclerotic morphea after treatment with antithymocyte globulin. Nat Rev Rheumatol. 2009 Sep; 5(9):513-6. PMID: 19710673.
        View in: PubMed
      18. Boin F, Franchini S, Colantuoni E, Rosen A, Wigley FM, Casciola-Rosen L. Independent association of anti-beta(2)-glycoprotein I antibodies with macrovascular disease and mortality in scleroderma patients. Arthritis Rheum. 2009 Aug; 60(8):2480-9. PMID: 19644882; PMCID: PMC2746063.
      19. Boin F, Wigley F. Connective tissue diseases: Immunosuppressive therapy in SSc: what is the target? Nat Rev Rheumatol. 2009 Jul; 5(7):357-8. PMID: 19568247.
        View in: PubMed
      20. Loizos N, Lariccia L, Weiner J, Griffith H, Boin F, Hummers L, Wigley F, Kussie P. Lack of detection of agonist activity by antibodies to platelet-derived growth factor receptor alpha in a subset of normal and systemic sclerosis patient sera. Arthritis Rheum. 2009 Apr; 60(4):1145-51. PMID: 19333919.
        View in: PubMed
      21. Boin F, De Fanis U, Bartlett SJ, Wigley FM, Rosen A, Casolaro V. T cell polarization identifies distinct clinical phenotypes in scleroderma lung disease. Arthritis Rheum. 2008 Apr; 58(4):1165-74. PMID: 18383361; PMCID: PMC2662772.
      22. Boin F, Hummers LK. Scleroderma-like fibrosing disorders. Rheum Dis Clin North Am. 2008 Feb; 34(1):199-220; ix. PMID: 18329541; PMCID: PMC2706095.
      23. Boin F, Rosen A. Autoimmunity in systemic sclerosis: current concepts. Curr Rheumatol Rep. 2007 May; 9(2):165-72. PMID: 17502048.
        View in: PubMed
      24. Boin F, Sciubba JJ, Stone JH. Churg-Strauss syndrome presenting with salivary gland enlargement and respiratory distress. Arthritis Rheum. 2006 Feb 15; 55(1):167-70. PMID: 16463394.
        View in: PubMed
      25. Boin F, Wigley FM, Schneck JP, Oelke M, Rosen A. Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis. Ann N Y Acad Sci. 2005 Dec; 1062:137-45. PMID: 16461796.
        View in: PubMed
      26. Boin F, Wigley FM. Understanding, assessing and treating Raynaud's phenomenon. Curr Opin Rheumatol. 2005 Nov; 17(6):752-60. PMID: 16224254.
        View in: PubMed
      27. Ponti C, Gibellini D, Boin F, Melloni E, Manzoli FA, Cocco L, Zauli G, Vitale M. Role of CREB transcription factor in c-fos activation in natural killer cells. Eur J Immunol. 2002 Dec; 32(12):3358-65. PMID: 12432566.
        View in: PubMed
      28. Maes M, Bocchio Chiavetto L, Bignotti S, Battisa Tura GJ, Pioli R, Boin F, Kenis G, Bosmans E, de Jongh R, Altamura CA. Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor. Schizophr Res. 2002 Apr 1; 54(3):281-91. PMID: 11950553.
        View in: PubMed
      29. Bocchio Chiavetto L, Boin F, Zanardini R, Popoli M, Michelato A, Bignotti S, Tura GB, Gennarelli M. Association between promoter polymorphic haplotypes of interleukin-10 gene and schizophrenia. Biol Psychiatry. 2002 Mar 15; 51(6):480-4. PMID: 11922883.
        View in: PubMed
      30. Boin F, Zanardini R, Pioli R, Altamura CA, Maes M, Gennarelli M. Association between -G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. Mol Psychiatry. 2001 Jan; 6(1):79-82. PMID: 11244489.
        View in: PubMed
      31. Maes M, Bocchio Chiavetto L, Bignotti S, Battisa Tura G, Pioli R, Boin F, Kenis G, Bosmans E, de Jongh R, Lin A, Racagni G, Altamura CA. Effects of atypical antipsychotics on the inflammatory response system in schizophrenic patients resistant to treatment with typical neuroleptics. Eur Neuropsychopharmacol. 2000 Mar; 10(2):119-24. PMID: 10706993.
        View in: PubMed
      32. Altamura AC, Boin F, Maes M. HPA axis and cytokines dysregulation in schizophrenia: potential implications for the antipsychotic treatment. Eur Neuropsychopharmacol. 1999 Dec; 10(1):1-4. PMID: 10647089.
        View in: PubMed
      33. Ossi E, Bordin MC, Businaro MA, Marson P, Bonadonna P, Chiaramonte M, Boin F, Valenti MT, Fagiolo U. HLA expression in type II mixed cryoglobulinemia and chronic hepatitis C virus. Clin Exp Rheumatol. 1995 Nov-Dec; 13 Suppl 13:S91-3. PMID: 8730485.
        View in: PubMed
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