Gerold Grodsky, PhD
|School||UCSF School of Medicine|
|Address||513 Parnassus Ave|
San Francisco CA 94143
School or Department
|University of California, San Francisco||Ph.D.|| Graduate Division (Biochemistry)||1955|
|US Midwestern Islet Group||2013||Paul Lacy Prize|
|UCSF||2010||Creation of the Gerold Grodsky, PhD Chair in Diabetes Research|
|UCSF Diabetes Center||2009||Lifetime Achievement Award|
|US Western Metabolic Group||1990||Williams and Levine Award|
|National Institutes of Health||1986||Merit Award|
|Juvenile Diabetes Research Foundation||1984||David Rumbaugh Scientific Award|
Dr. Grodsky is currently a consultant to laboratories in the Diabetes Center. He was the developer of the first precipitating radio immunoassay (insulin). His group published over 200 papers on the mechanisms involved in the synthesis, storage and secretion of insulin, with emphasis on the kinetics and quantitative relationships of these mechanisms. From these studies came the description of the fast and slow phases of insulin release and the hypothesis that insulin is stored in compartments of differing availability for release. The rapid phase of insulin release was shown to be vital in the maintenance of glucose homeostasis and is being utilized in the design of the closed-loop artificial pancreas, faster acting beta-cell secretagogues, and fast absorbing insulin preparations.
Other areas of research activity includes the demonstration of insulin-induced auto antibodies and their contribution to beta-cell destruction.
Dr. Grodsky taught for 48 years focusing on regulation of glucose and energy Metabolism, insulin and diabetes. He served as Research Chairman of the Advisory Board for Diabetes to the Secretary of Health and on the editorial boards of numerous journals; he was the Founding Advisory Editor of the journal, "Diabetes Technology and Therapeutics" and is the Advisory Editor of the Journal of Diabetes Science and Technology. Since 1994, the Juvenile Diabetes Foundation, International has given an Annual Gerold Grodsky Award for basic research in diabetes.
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