Grayson Marshall, JR, DDS, PhD, MPH
|School||UCSF School of Dentistry|
|Department||Preventive & Restor Dent Sci|
|Address||707 Parnassus Ave, Dentistry|
San Francisco CA 94143
|Virginia Tech||BS||Metallurgical Engineering|
|Northwestern University||DDS||Dental School|
|Northwestern University||PhD||Graduate School|
|Northwestern University||Post-Doctoral Scholar||Biological Materials|
|University of Melbourne (Australia)||Visiting Fellow ||Prosthodontics|
|University of California Berkeley||Master of Public Health||Epidemiology|
|Malmo University (Sweden)||Dr. of Odontology. (h.c.)||Odontology|
Grayson W. Marshall, Jr received a BS degree in engineering at Virginia Tech , a DDS and PhD from Northwestern University, an MPH in epidemiology from U.C. Berkeley., and an honorary doctorate from Malmo University, Malmo, Sweden. Dr. Marshall was a post-doctoral scholar in biological materials at Northwestern and a visiting fellow at University of Melbourne, Victoria, Australia. He served on the Northwestern University faculty from 1973-87, before joining UCSF where he is currently Distinguished Professor Emeritus. He has served as Chair of the Division of Biomaterials and Bioengineering 1988-present, and Vice Chair, Dept. of Preventive and Restorative Dental Sciences from 2005-12. . Dr. Marshall served as Director for the UCSF Comprehensive Oral Health Research Training (COHORT) Program (2001-08), the Dentist Scientist Award Program (1996-2004) and the Integrated DDS/PhD Program (1996-08); he was Chair of the Oral and Craniofacial Sciences (OCS) Graduate Group (2002-07), and is a member of several other UCSF graduate programs and groups. He holds fellowships in AAAS, the Academy of Dental Materials, American College of Dentists, the International College of Dentists, and the American Assoc. for Dental Research.. In 2007 he received the IADR Wilmer Souder Distinguished Scientist Award, and in 2009 the ADM Founders Award. He served as President of the American Association for Dental Research in 2009-10.
Our research group studies structure-mechanical property relationships of calcified tissues (bone, cementum, dentin, enamel). The main functions of these biological materials are mechanical, but much work is needed to understand how their unique and versatile properties are derived based on combinations of protein and mineral. We seek insight into biomineralization processes associated with these tissues during development, alterations resulting from disease, or repair and regeneration from clinical treatments. We also focus on natural interfaces between various calcified tissues and artificial interfaces between the tissues and artificial materials, e.g., dental restorations, implants, bioactive substrates. We use a wide variety of approaches including atomic force microscopy (AFM; and AFM-based nano-indentation) as well as other high resolution imaging methods and participate in wide ranging collaborations in the Bay Area. This work helps define alteration in properties and structure with hydration state, mineral level, and variations induced by disease and physiological processes. This information is needed to develop a composite structural model of calcified tissues and can assist in the development of bioinspired materials and tissue engineering.
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