 H.-Christian Von Buedingen, MD
|
| Address | 675 Nelson Rising Lane
San Francisco CA 94158
|
|---|
| Phone | 415-476-9046 |
|---|
|
|
 Biography | University of Göttingen, Germany | 2005 | | Helmut Bauer-Award for Multiple Sclerosis Research |
Overview Dr. H.-Christian von Büdingen earned his medical degree from the Johann-Wolfgang Goethe-University in Frankfurt/Main, Germany. He received his clinical training in Munich, Germany (1996-1997) and Zürich, Switzerland (2003-2008) where he also became a board-certified Neurologist. From 1998-2003 he was a postdoctoral fellow in Dr. Hauser's and Dr. Genain's neuroimmunology laboratory at UCSF. He became a lecturer in Neurology at the University of Zürich, Switzerland in 2008 and was staff physician and attending neurologist at a neurological rehabilitation hospital in Switzerland until 02/2009. He returned to UCSF in April 2009 to join the Department of Neurology's faculty as Assistant Professor.
Dr. von Büdingen is a clinician-scientist whose work focuses on B cell and antibody related immune mechanisms in MS. His doctoral thesis was awarded "summa cum laude" from the Johann-Wolfgang Goethe University, Frankfurt/Main, Germany in 1997. He has received post-doctoral research fellowship awards from the National Institutes of Health, the National Multiple Sclerosis Society, the German MS Society, the Hertie-Foundation (Germany) and the Stiefel-Zangger-Foundation (University of Zürich, Switzerland). His laboratory studies the origin, specificity and effect of B cell and antibody mediated immunity in multiple sclerosis (MS) and neuromyelitis optica (NMO). Dr. von Büdingen also recently began to work with induced pluripotent stem cells from patients to create in vitro models of MS and NMO to better understand mechanisms of tissue injury and repair.
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Researchers can login to make corrections and additions, or contact us for help.
-
von Büdingen HC, Kuo TC, Sirota M, van Belle CJ, Apeltsin L, Glanville J, Cree BA, Gourraud PA, Schwartzburg A, Huerta G, Telman D, Sundar PD, Casey T, Cox DR, Hauser SL. B cell exchange across the blood-brain barrier in multiple sclerosis. J Clin Invest. 2012 Dec 3; 122(12):4533-43.
-
Glanville J, Kuo TC, von Büdingen HC, Guey L, Berka J, Sundar PD, Huerta G, Mehta GR, Oksenberg JR, Hauser SL, Cox DR, Rajpal A, Pons J. Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20066-71.
-
Menge T, Lalive PH, von Büdingen HC, Genain CP. Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis. J Neuroinflammation. 2011; 8:161.
-
von Büdingen HC, Bar-Or A, Zamvil SS. B cells in multiple sclerosis: connecting the dots. Curr Opin Immunol. 2011 Dec; 23(6):713-20.
-
von Büdingen HC, Gulati M, Kuenzle S, Fischer K, Rupprecht TA, Goebels N. Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce "oligoclonal bands". J Neuroimmunol. 2010 Jan 25; 218(1-2):134-9.
-
Harrer MD, von Büdingen HC, Stoppini L, Alliod C, Pouly S, Fischer K, Goebels N. Live imaging of remyelination after antibody-mediated demyelination in an ex-vivo model for immune mediated CNS damage. Exp Neurol. 2009 Apr; 216(2):431-8.
-
von Büdingen HC, Harrer MD, Kuenzle S, Meier M, Goebels N. Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin-specific antibodies. Eur J Immunol. 2008 Jul; 38(7):2014-23.
-
Menge T, Weber MS, Hemmer B, Kieseier BC, von Büdingen HC, Warnke C, Zamvil SS, Boster A, Khan O, Hartung HP, Stüve O. Disease-modifying agents for multiple sclerosis: recent advances and future prospects. Drugs. 2008; 68(17):2445-68.
-
Menge T, von Büdingen HC, Lalive PH, Genain CP. Relevant antibody subsets against MOG recognize conformational epitopes exclusively exposed in solid-phase ELISA. Eur J Immunol. 2007 Nov; 37(11):3229-39.
-
Kuenzle S, von Büdingen HC, Meier M, Harrer MD, Urich E, Becher B, Goebels N. Pathogen specificity and autoimmunity are distinct features of antigen-driven immune responses in neuroborreliosis. Infect Immun. 2007 Aug; 75(8):3842-7.
-
Stüve O, Youssef S, Weber MS, Nessler S, von Büdingen HC, Hemmer B, Prod'homme T, Sobel RA, Steinman L, Zamvil SS. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. J Clin Invest. 2006 Apr; 116(4):1037-44.
-
von Büdingen HC, Menge T, Hauser SL, Genain CP. Restrictive and diversifying elements of the anti-myelin/oligodendrocyte glycoprotein antibody response in primate experimental allergic encephalomyelitis. Immunogenetics. 2006 Apr; 58(2-3):122-8.
-
Lalive PH, Menge T, Delarasse C, Della Gaspera B, Pham-Dinh D, Villoslada P, von Büdingen HC, Genain CP. Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2280-5.
-
von Büdingen HC, Staudacher T, von Büdingen HJ. Ultrasound diagnostics of the vertebrobasilar system. Front Neurol Neurosci. 2006; 21:57-69.
-
Menge T, Lalive PH, von Büdingen HC, Cree B, Hauser SL, Genain CP. Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis. J Allergy Clin Immunol. 2005 Aug; 116(2):453-9.
-
Menge T, von Büdingen HC, Zamvil SS, Hartung HP, Kieseier BC, Stüve O. [Statins for treatment of CNS diseases. Status report from research and clinical practice]. Nervenarzt. 2005 Apr; 76(4):426-37.
-
von Büdingen HC, Hauser SL, Ouallet JC, Tanuma N, Menge T, Genain CP. Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. Eur J Immunol. 2004 Aug; 34(8):2072-83.
-
von Büdingen HC, Skulina C. Following the tracks of immune responses. Trends Biotechnol. 2003 Oct; 21(10):415-7.
-
Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. Neurologist. 2002 Sep; 8(5):290-301.
-
von Büdingen HC, Hauser SL, Fuhrmann A, Nabavi CB, Lee JI, Genain CP. Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8207-12.
-
von Büdingen HC, Hauser SL, Nabavi CB, Genain CP. Characterization of the expressed immunoglobulin IGHV repertoire in the New World marmoset Callithrix jacchus. Immunogenetics. 2001 Sep; 53(7):557-63.
-
von Büdingen HC, Tanuma N, Villoslada P, Ouallet JC, Hauser SL, Genain CP. Immune responses against the myelin/oligodendrocyte glycoprotein in experimental autoimmune demyelination. J Clin Immunol. 2001 May; 21(3):155-70.
|
H.-Christian's Networks
Click the "See All" links for more information and interactive visualizations!
Related Concepts Derived automatically from this person's publications. _
Co-Authors People in Profiles who have published with this person. _
Related Authors People who share similar concepts with this person. _
|
