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Herbert Kasler, PhD

TitlePostdoctoral Fellow
SchoolUCSF School of Medicine
DepartmentGladstone Institutes
Address1650 Owens Street
San Francisco CA 94143
Phone415-734-4917
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP. Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. Cell Rep. 2017 May 23; 19(8):1558-1571. PMID: 28538176.
      View in: PubMed
    2. Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E. SIRT1 deacetylates ROR?t and enhances Th17 cell generation. J Exp Med. 2015 Jun 01; 212(6):973. PMID: 25987725; PMCID: PMC4451124.
    3. Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E. SIRT1 deacetylates ROR?t and enhances Th17 cell generation. J Exp Med. 2015 May 04; 212(5):607-17. PMID: 25918343; PMCID: PMC4419343.
    4. Kasler HG, Lim HW, Mottet D, Collins AM, Lee IS, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. EMBO J. 2012 Nov 28; 31(23):4453-65. PMID: 23103766; PMCID: PMC3512390.
    5. Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol. 2011 Apr 15; 186(8):4782-93. PMID: 21398603.
      View in: PubMed
    6. Kasler HG, Verdin E. Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes. Mol Cell Biol. 2007 Jul; 27(14):5184-200. PMID: 17470548; PMCID: PMC1951960.
    7. Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J Biol Chem. 2005 Apr 08; 280(14):13762-70. PMID: 15623513.
      View in: PubMed
    8. Verdin E, Dequiedt F, Kasler H. HDAC7 regulates apoptosis in developing thymocytes. Novartis Found Symp. 2004; 259:115-29; discussion 129-31, 163-9. PMID: 15171250.
      View in: PubMed
    9. Verdin E, Dequiedt F, Kasler HG. Class II histone deacetylases: versatile regulators. Trends Genet. 2003 May; 19(5):286-93. PMID: 12711221.
      View in: PubMed
    10. Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity. 2003 May; 18(5):687-98. PMID: 12753745.
      View in: PubMed
    11. Kasler HG, Victoria J, Duramad O, Winoto A. ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain. Mol Cell Biol. 2000 Nov; 20(22):8382-9. PMID: 11046135; PMCID: PMC102145.
    12. Zhang J, DeYoung A, Kasler HG, Kabra NH, Kuang AA, Diehl G, Sohn SJ, Bishop C, Winoto A. Receptor-mediated apoptosis in T lymphocytes. Cold Spring Harb Symp Quant Biol. 1999; 64:363-71. PMID: 11232309.
      View in: PubMed
    13. Theofan G, Horwitz AH, Williams RE, Liu PS, Chan I, Birr C, Carroll SF, Mészáros K, Parent JB, Kasler H. An amino-terminal fragment of human lipopolysaccharide-binding protein retains lipid A binding but not CD14-stimulatory activity. J Immunol. 1994 Apr 01; 152(7):3623-9. PMID: 7511654.
      View in: PubMed
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