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    Hirofumi Noguchi, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentNeurology
    Address675 Nelson Rising Lane
    San Francisco CA 94158
    Phone415-514-4949
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Noguchi H, Kimura A, Murao N, Namihira M, Nakashima K. Prenatal deletion of DNA methyltransferase 1 in neural stem cells impairs neurogenesis and causes anxiety-like behavior in adulthood. Neurogenesis (Austin). 2016; 3(1):e1232679. PMID: 27844025.
        View in: PubMed
      2. Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I. Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions. Nat Biotechnol. 2016 Oct; 34(10):1060-1065. PMID: 27571369.
        View in: PubMed
      3. Noguchi H, Murao N, Kimura A, Matsuda T, Namihira M, Nakashima K. DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus. J Neurosci. 2016 Jun 1; 36(22):6050-68. PMID: 27251626.
        View in: PubMed
      4. Noguchi H. Creating a Future of Transplantation. Cell Med. 2015 Dec 17; 8(1-2):1. PMID: 26858902.
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      5. Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H. Cryopreservation of Adipose-Derived Mesenchymal Stem Cells. Cell Med. 2015 Dec 17; 8(1-2):3-7. PMID: 26858903.
        View in: PubMed
      6. Saitoh I, Inada E, Iwase Y, Noguchi H, Murakami T, Soda M, Kubota N, Hasegawa H, Akasaka E, Matsumoto Y, Oka K, Yamasaki Y, Hayasaki H, Sato M. Choice of Feeders Is Important When First Establishing iPSCs Derived From Primarily Cultured Human Deciduous Tooth Dental Pulp Cells. Cell Med. 2015 Dec 17; 8(1-2):9-23. PMID: 26858904.
        View in: PubMed
      7. Noguchi H, Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M. Islet Culture/Preservation Before Islet Transplantation. Cell Med. 2015 Dec 17; 8(1-2):25-9. PMID: 26858905.
        View in: PubMed
      8. Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S. Spheroid Formation and Evaluation of Hepatic Cells in a Three-Dimensional Culture Device. Cell Med. 2015 Dec 17; 8(1-2):47-56. PMID: 26858908.
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      9. Noguchi H, Kimura A, Murao N, Matsuda T, Namihira M, Nakashima K. Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus. Neurosci Res. 2015 Jun; 95:1-11. PMID: 25659757.
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      10. Tsugata T, Nikoh N, Kin T, Saitoh I, Noguchi Y, Ueki H, Watanabe M, James Shapiro AM, Noguchi H. Potential Factors for the Differentiation of ESCs/iPSCs Into Insulin-Producing Cells. Cell Med. 2015 Feb 8; 7(2):83-93. PMID: 26858897.
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      11. Noguchi H. Basic and Clinical Science for Organ Biology. Cell Med. 2015 Feb 8; 7(2):49. PMID: 26858892.
        View in: PubMed
      12. Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S. Three-Dimensional In Vitro Hepatic Constructs Formed Using Combinatorial Tapered Stencil for Cluster Culture (TASCL) Device. Cell Med. 2015 Feb 8; 7(2):67-74. PMID: 26858895.
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      13. Murao N, Matsuda T, Noguchi H, Koseki H, Namihira M, Nakashima K. Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells. Neurogenesis (Austin). 2014; 1(1):e976026. PMID: 27504471.
        View in: PubMed
      14. Yukawa H, Nakagawa S, Yoshizumi Y, Watanabe M, Saito H, Miyamoto Y, Noguchi H, Oishi K, Ono K, Sawada M, Kato I, Onoshima D, Obayashi M, Hayashi Y, Kaji N, Ishikawa T, Hayashi S, Baba Y. Novel positively charged nanoparticle labeling for in vivo imaging of adipose tissue-derived stem cells. PLoS One. 2014; 9(11):e110142. PMID: 25365191; PMCID: PMC4217721.
      15. Shimoda M, Chen S, Noguchi H, Takita M, Sugimoto K, Itoh T, Chujo D, Iwahashi S, Naziruddin B, Levy MF, Matsumoto S, Grayburn PA. A new method for generating insulin-secreting cells from human pancreatic epithelial cells after islet isolation transformed by NeuroD1. Hum Gene Ther Methods. 2014 Jun; 25(3):206-19. PMID: 24845703; PMCID: PMC4060820.
      16. Kuise T, Noguchi H, Tazawa H, Kawai T, Iwamuro M, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells. Biomed Eng Online. 2014; 13:64. PMID: 24886514; PMCID: PMC4055227.
      17. Adefuin AM, Kimura A, Noguchi H, Nakashima K, Namihira M. Epigenetic mechanisms regulating differentiation of neural stem/precursor cells. Epigenomics. 2014; 6(6):637-49. PMID: 25531257.
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      18. Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei FY, Hakim F, Kume S, Tomizawa K. Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors. Stem Cells Transl Med. 2014 Jan; 3(1):114-27. PMID: 24292793; PMCID: PMC3902286.
      19. Murakami T, Saitoh I, Inada E, Kurosawa M, Iwase Y, Noguchi H, Terao Y, Yamasaki Y, Hayasaki H, Sato M. STO Feeder Cells Are Useful for Propagation of Primarily Cultured Human Deciduous Dental Pulp Cells by Eliminating Contaminating Bacteria and Promoting Cellular Outgrowth. Cell Med. 2013 Dec 30; 6(1-2):75-81. PMID: 26858883.
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      20. Noguchi H. Organ Biology-New Development. Cell Med. 2013 Dec 30; 6(1-2):1-2. PMID: 26858873.
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      21. Katayama A, Noguchi H, Kuise T, Nakatsuka A, Hirota D, Kataoka HU, Kawai T, Inoue K, Imagawa N, Saitoh I, Noguchi Y, Watanabe M, Wada J, Fujiwara T. Comparison of New Preservation Solutions, HN-1 and University of Wisconsin Solution, in Pancreas Preservation for Porcine Islet Isolation. Cell Med. 2013 Dec 30; 6(1-2):3-8. PMID: 26858874.
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      22. Kawai T, Noguchi H, Kuise T, Nakatsuka A, Katayama A, Imagawa N, Kataoka HU, Saitoh I, Noguchi Y, Watanabe M, Fujiwara T. Comparison of Incubation Solutions Prior to the Purification of Porcine Islet Cells. Cell Med. 2013 Dec 30; 6(1-2):9-14. PMID: 26858875.
        View in: PubMed
      23. Kubota Y, Noguchi H, Seita M, Yuasa T, Sasamoto H, Nakaji S, Okitsu T, Fujiwara T, Kobayashi N. Maintenance of Viability and Function of Rat Islets With the Use of ROCK Inhibitor Y-27632. Cell Med. 2013 Dec 30; 6(1-2):15-23. PMID: 26858876.
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      24. Seita M, Noguchi H, Kubota Y, Kawamoto H, Nakaji S, Kobayashi N, Fujiwara T. Development of Canine Models of Type 1 Diabetes With Partial Pancreatectomy and the Administration of Streptozotocin. Cell Med. 2013 Dec 30; 6(1-2):25-31. PMID: 26858877.
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      25. Yuniarti N, Juliandi B, MuhChyi C, Noguchi H, Sanosaka T, Nakashima K. Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis. Neurosci Res. 2013 Sep-Oct; 77(1-2):42-9. PMID: 23831515.
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      26. Kataoka HU, Noguchi H. ER Stress and ß-Cell Pathogenesis of Type 1 and Type 2 Diabetes and Islet Transplantation. Cell Med. 2013 Nov 10; 5(2-3):53-7. PMID: 26858865.
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      27. Noguchi H, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Culture Conditions for Mouse Pancreatic Stem Cells. Cell Med. 2013 Nov 10; 5(2-3):63-8. PMID: 26858867.
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      28. Kuise T, Noguchi H, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T. Isolation Efficiency of Mouse Pancreatic Stem Cells Is Age Dependent. Cell Med. 2013 Nov 10; 5(2-3):69-73. PMID: 26858868.
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      29. Miyamoto Y, Koshidaka Y, Noguchi H, Oishi K, Saito H, Yukawa H, Kaji N, Ikeya T, Suzuki S, Iwata H, Baba Y, Murase K, Hayashi S. Observation of Positively Charged Magnetic Nanoparticles Inside HepG2 Spheroids Using Electron Microscopy. Cell Med. 2013 Nov 10; 5(2-3):89-96. PMID: 26858871.
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      30. Noguchi H. Long-Expected New Start. Cell Med. 2013 Nov 10; 5(2-3):43. PMID: 26858863.
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      31. Oishi K, Miyamoto Y, Saito H, Murase K, Ono K, Sawada M, Watanabe M, Noguchi Y, Fujiwara T, Hayashi S, Noguchi H. In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle. PLoS One. 2013; 8(2):e57046. PMID: 23451139; PMCID: PMC3579774.
      32. Sugimoto M, Watanabe M, Kaku H, Li SA, Noguchi H, Ueki H, Sakaguchi M, Huh NH, Nasu Y, Kumon H. Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy. Oncol Rep. 2012 Nov; 28(5):1645-52. PMID: 22941469.
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      33. Ueki H, Watanabe M, Kaku H, Huang P, Li SA, Ochiai K, Hirata T, Noguchi H, Yamada H, Takei K, Nasu Y, Kashiwakura Y, Kumon H. A novel gene expression system for detecting viable bladder cancer cells. Int J Oncol. 2012 Jul; 41(1):135-40. PMID: 22470055.
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      34. Kanamune J, Iwanaga Y, Kina T, Noguchi H, Matsumura K, Uemoto S, Hyon SH. Attenuation of murine graft-versus-host disease by a tea polyphenol. Cell Transplant. 2012; 21(5):909-18. PMID: 22330060.
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      35. Noguchi H. Stem cell applications in diabetes. J Stem Cells. 2012; 7(4):229-44. PMID: 24196798.
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      36. Noguchi H, Naziruddin B, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Evaluation of osmolality of density gradient for human islet purification. Cell Transplant. 2012; 21(2-3):493-500. PMID: 22793057.
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      37. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Fresh islets are more effective for islet transplantation than cultured islets. Cell Transplant. 2012; 21(2-3):517-23. PMID: 22793060.
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      38. Naziruddin B, Matsumoto S, Noguchi H, Takita M, Shimoda M, Fujita Y, Chujo D, Tate C, Onaca N, Lamont J, Kobayashi N, Levy MF. Improved pancreatic islet isolation outcome in autologous transplantation for chronic pancreatitis. Cell Transplant. 2012; 21(2-3):553-8. PMID: 22793064.
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      39. Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S. Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using a1-antitrypsin. Cell Transplant. 2012; 21(2-3):465-71. PMID: 22793054.
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      40. Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S. Islet purification method using large bottles effectively achieves high islet yield from pig pancreas. Cell Transplant. 2012; 21(2-3):501-8. PMID: 22793058.
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      41. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Ueda M, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Onaca N, Levy MF, Matsumoto S. Comparison of ulinastatin, gabexate mesilate, and nafamostat mesilate in preservation solution for islet isolation. Cell Transplant. 2012; 21(2-3):509-16. PMID: 22793059.
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      42. Takita M, Matsumoto S, Noguchi H, Shimoda M, Ikemoto T, Chujo D, Tamura Y, Olsen GS, Naziruddin B, Purcell K, Onaca N, Levy MF. Adverse events in clinical islet transplantation: one institutional experience. Cell Transplant. 2012; 21(2-3):547-51. PMID: 22793063.
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      43. Hayashi T, Misawa H, Nakahara H, Noguchi H, Yoshida A, Kobayashi N, Tanaka M, Ozaki T. Transplantation of osteogenically differentiated mouse iPS cells for bone repair. Cell Transplant. 2012; 21(2-3):591-600. PMID: 22793068.
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      44. Miyamoto Y, Oishi K, Yukawa H, Noguchi H, Sasaki M, Iwata H, Hayashi S. Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin. Cell Transplant. 2012; 21(2-3):617-22. PMID: 22793071.
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      45. Kuise T, Noguchi H. Recent progress in pancreatic islet transplantation. World J Transplant. 2011 Dec 24; 1(1):13-8. PMID: 24175188; PMCID: PMC3782227.
      46. Yukawa H, Watanabe M, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Baba Y, Hayashi S. Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots. Biomaterials. 2012 Mar; 33(7):2177-86. PMID: 22192539.
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      47. Noguchi H, Yamada T, Tanaka K. [Islet transplantation]. Nihon Rinsho. 2011 Dec; 69(12):2209-13. PMID: 22242321.
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      48. Obika M, Noguchi H. Diagnosis and evaluation of nonalcoholic fatty liver disease. Exp Diabetes Res. 2012; 2012:145754. PMID: 22110476; PMCID: PMC3205741.
      49. Takasaki Y, Watanabe M, Yukawa H, Sabarudin A, Inagaki K, Kaji N, Okamoto Y, Tokeshi M, Miyamoto Y, Noguchi H, Umemura T, Hayashi S, Baba Y, Haraguchi H. Estimation of the distribution of intravenously injected adipose tissue-derived stem cells labeled with quantum dots in mice organs through the determination of their metallic components by ICPMS. Anal Chem. 2011 Nov 1; 83(21):8252-8. PMID: 21958307.
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      50. Noguchi H. Pancreas procurement and preservation for islet transplantation: personal considerations. J Transplant. 2011; 2011:783168. PMID: 21918716; PMCID: PMC3171759.
      51. Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H. Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1. Biochem Biophys Res Commun. 2011 Aug 26; 412(2):391-5. PMID: 21835165.
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      52. Minami K, Doi R, Kawaguchi Y, Nukaya D, Hagiwara Y, Noguchi H, Matsumoto S, Seino S. In vitro generation of insulin-secreting cells from human pancreatic exocrine cells. J Diabetes Investig. 2011 Aug 2; 2(4):271-5. PMID: 24843497; PMCID: PMC4014966.
      53. Takita M, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Sorelle JA, Onaca N, Naziruddin B, Levy MF. Cluster analysis of self-monitoring blood glucose assessments in clinical islet cell transplantation for type 1 diabetes. Diabetes Care. 2011 Aug; 34(8):1799-803. PMID: 21680718; PMCID: PMC3142013.
      54. Takita M, Matsumoto S, Qin H, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Naziruddin B, Levy MF. Secretory unit of islet transplant objects (SUITO) index can predict severity of hypoglycemic episodes in clinical islet cell transplantation. Cell Transplant. 2012; 21(1):91-8. PMID: 21669043.
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      55. Matsumoto S, Takita M, Chaussabel D, Noguchi H, Shimoda M, Sugimoto K, Itoh T, Chujo D, SoRelle J, Onaca N, Naziruddin B, Levy MF. Improving efficacy of clinical islet transplantation with iodixanol-based islet purification, thymoglobulin induction, and blockage of IL-1ß and TNF-a. Cell Transplant. 2011; 20(10):1641-7. PMID: 21396171.
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      56. Yukawa H, Ikeuchi M, Noguchi H, Miyamoto Y, Ikuta K, Hayashi S. Embryonic body formation using the tapered soft stencil for cluster culture device. Biomaterials. 2011 May; 32(15):3729-38. PMID: 21354615.
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      57. Ikemoto T, Sugimoto K, Takita M, Shimoda M, Noguchi H, Naziruddin B, Levy MF, Shimada M, Matsumoto S. Japanese herbal medicine TJ-48 prevents autoimmune diabetes in NOD mice. Am J Chin Med. 2011; 39(4):743-56. PMID: 21721154.
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      58. Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Lamont J, Lara LF, Levy MF. Implication of pancreatic image findings in total pancreatectomy with islet autotransplantation for chronic pancreatitis. Pancreas. 2011 Jan; 40(1):103-8. PMID: 20881896.
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      59. Fujita Y, Takita M, Shimoda M, Itoh T, Sugimoto K, Noguchi H, Naziruddin B, Levy MF, Matsumoto S. Large human islets secrete less insulin per islet equivalent than smaller islets in vitro. Islets. 2011 Jan-Feb; 3(1):1-5. PMID: 21266855.
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      60. Takita M, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Sugimoto K, Itoh T, Lamont JP, Lara LF, Onaca N, Naziruddin B, Klintmalm GB, Levy MF. One hundred human pancreatic islet isolations at Baylor Research Institute. Proc (Bayl Univ Med Cent). 2010 Oct; 23(4):341-8. PMID: 20944753; PMCID: PMC2943445.
      61. Ikemoto T, Noguchi H, Fujita Y, Takita M, Shimoda M, Sugimoto K, Jackson A, Naziruddin B, Shimada M, Levy MF, Matsumoto S. New stepwise cooling system for short-term porcine islet preservation. Pancreas. 2010 Oct; 39(7):960-3. PMID: 20467350.
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      62. Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Lamont J, Lara LF, Levy MF. Reconstruction of pancreatic duct for previous Puestow operation for an islet autotransplantation. Transplantation. 2010 Aug 27; 90(4):458-9. PMID: 20720478.
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      63. Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Tamura Y, Olsen GS, Onaca N, Lamont J, Lara LF, Levy MF. Body mass index reflects islet isolation outcome in islet autotransplantation for patients with chronic pancreatitis. Cell Transplant. 2011; 20(2):313-22. PMID: 20719073.
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      64. Noguchi H. Pancreatic stem/progenitor cells for the treatment of diabetes. Rev Diabet Stud. 2010; 7(2):105-11. PMID: 21060969; PMCID: PMC2989783.
      65. Navarro-Alvarez N, Kondo E, Kawamoto H, Hassan W, Yuasa T, Kubota Y, Seita M, Nakahara H, Hayashi T, Nishikawa Y, Hassan RA, Javed SM, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N, Soto-Gutierrez A. Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties. Cell Transplant. 2010; 19(6):865-77. PMID: 20587145; PMCID: PMC2957535.
      66. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Kobayashi N, Onaca N, Hayashi S, Levy MF, Matsumoto S. Characterization of human pancreatic progenitor cells. Cell Transplant. 2010; 19(6):879-86. PMID: 20587146.
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      67. Oishi K, Noguchi H, Saito H, Yukawa H, Miyamoto Y, Murase K, Hayashi S. Cell labeling with a novel contrast agent of magnetic resonance imaging. Cell Transplant. 2010; 19(6):887-92. PMID: 20587147.
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      68. Oishi K, Noguchi H, Yukawa H, Inoue M, Miyamoto Y, Iwata H, Hasegawa M, Hayashi S. Efficient transfection of sendai virus vector to mouse pancreatic stem cells in the floating state. Cell Transplant. 2010; 19(6):893-900. PMID: 20587148.
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      69. Yukawa H, Noguchi H, Nakase I, Miyamoto Y, Oishi K, Hamajima N, Futaki S, Hayashi S. Transduction of cell-penetrating peptides into induced pluripotent stem cells. Cell Transplant. 2010; 19(6):901-9. PMID: 20587149.
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      70. Yamamoto T, Navarro-Alvarez N, Soto-Gutierrez A, Yuasa T, Iwamuro M, Kubota Y, Seita M, Kawamoto H, Javed SM, Kondo E, Noguchi H, Kobayashi S, Nakaji S, Kobayashi N. Treatment of acute liver failure in mice by hepatocyte xenotransplantation. Cell Transplant. 2010; 19(6):799-806. PMID: 20573299; PMCID: PMC2957529.
      71. Noguchi H, Matsushita M, Kobayashi N, Levy MF, Matsumoto S. Recent advances in protein transduction technology. Cell Transplant. 2010; 19(6):649-54. PMID: 20525440.
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      72. Ikemoto T, Matsumoto S, Itoh T, Noguchi H, Tamura Y, Jackson AM, Shimoda M, Naziruddin B, Onaca N, Yasunami Y, Levy MF. Assessment of islet quality following international shipping of more than 10,000 km. Cell Transplant. 2010; 19(6):731-41. PMID: 20525435.
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      73. Noguchi H. Production of pancreatic beta-cells from stem cells. Curr Diabetes Rev. 2010 May; 6(3):184-90. PMID: 20380628.
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      74. Takita M, Naziruddin B, Matsumoto S, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Lamont JP, Lara LF, Levy MF. Variables associated with islet yield in autologous islet cell transplantation for chronic pancreatitis. Proc (Bayl Univ Med Cent). 2010 Apr; 23(2):115-20. PMID: 20396418; PMCID: PMC2848085.
      75. Yukawa H, Kagami Y, Watanabe M, Oishi K, Miyamoto Y, Okamoto Y, Tokeshi M, Kaji N, Noguchi H, Ono K, Sawada M, Baba Y, Hamajima N, Hayashi S. Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells. Biomaterials. 2010 May; 31(14):4094-103. PMID: 20171733.
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      76. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Low-temperature preservation of isolated islets is superior to conventional islet culture before islet transplantation. Transplantation. 2010 Jan 15; 89(1):47-54. PMID: 20061918.
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      77. Noguchi H, Naziruddin B, Onaca N, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Kobayashi N, Levy MF, Matsumoto S. Comparison of modified Celsior solution and M-kyoto solution for pancreas preservation in human islet isolation. Cell Transplant. 2010; 19(6):751-8. PMID: 20955657.
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      78. Shahid JM, Iwamuro M, Sasamoto H, Kubota Y, Seita M, Kawamoto H, Nakaji S, Noguchi H, Yamamoto K, Kobayashi N. Establishment of an immortalized porcine liver cell line JSNK-1 with retroviral transduction of SV40T. Cell Transplant. 2010; 19(6):849-56. PMID: 20955660.
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      79. Noguchi H. Recent advances in stem cell research for the treatment of diabetes. World J Stem Cells. 2009 Dec 31; 1(1):36-42. PMID: 21607105; PMCID: PMC3097914.
      80. Noguchi H. Pancreatic islet transplantation. World J Gastrointest Surg. 2009 Nov 30; 1(1):16-20. PMID: 21160790; PMCID: PMC2999120.
      81. Nakahara H, Misawa H, Hayashi T, Kondo E, Yuasa T, Kubota Y, Seita M, Kawamoto H, Hassan WA, Hassan RA, Javed SM, Tanaka M, Endo H, Noguchi H, Matsumoto S, Takata K, Tashiro Y, Nakaji S, Ozaki T, Kobayashi N. Bone repair by transplantation of hTERT-immortalized human mesenchymal stem cells in mice. Transplantation. 2009 Aug 15; 88(3):346-53. PMID: 19667936.
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      82. Noguchi H, Ikemoto T, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Kobayashi N, Onaca N, Levy MF, Matsumoto S. Iodixanol-controlled density gradient during islet purification improves recovery rate in human islet isolation. Transplantation. 2009 Jun 15; 87(11):1629-35. PMID: 19502953.
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      83. Jackson AM, Connolly JE, Matsumoto S, Noguchi H, Onaca N, Levy MF, Naziruddin B. Evidence for Induced Expression of HLA Class II on Human Islets: Possible Mechanism for HLA Sensitization in Transplant Recipients. Transplantation. 2009 Feb 27; 87(4):500-6. PMID: 19307785.
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      84. Onaca N, Naziruddin B, Randall HB, Meler JD, Sanchez EQ, Matsumoto S, Noguchi H, Jackson A, Diamond NG, Klintmalm GB, Levy MF. False aneurysm of a hepatic artery branch complicating intrahepatic islet transplantation. Transpl Int. 2009 Jun; 22(6):663-6. PMID: 19175561.
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      85. Noguchi H, Levy MF, Kobayashi N, Matsumoto S. Pancreas preservation by the two-layer method: does it have a beneficial effect compared with simple preservation in University of Wisconsin solution? Cell Transplant. 2009; 18(5):497-503. PMID: 19775509.
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      86. Noguchi H, Ueda M, Hayashi S, Kobayashi N, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Levy MF, Matsumoto S. Comparison of trypsin inhibitors in preservation solution for islet isolation. Cell Transplant. 2009; 18(5):541-7. PMID: 19775515.
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      87. Matsumoto S, Noguchi H, Hatanaka N, Shimoda M, Kobayashi N, Jackson A, Onaca N, Naziruddin B, Levy MF. Estimation of donor usability for islet transplantation in the United States with the kyoto islet isolation method. Cell Transplant. 2009; 18(5):549-56. PMID: 19775516.
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      88. Matsumoto S, Noguchi H, Hatanaka N, Shimoda M, Kobayashi N, Jackson A, Onaca N, Naziruddin B, Levy MF. SUITO index for evaluation of efficacy of single donor islet transplantation. Cell Transplant. 2009; 18(5):557-62. PMID: 19775517.
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      89. Oishi K, Noguchi H, Yukawa H, Inoue M, Takagi S, Iwata H, Hasegawa M, Hayashi S. Recombinant sendai virus-mediated gene transfer to mouse pancreatic stem cells. Cell Transplant. 2009; 18(5):573-80. PMID: 19775519.
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      90. Oishi K, Noguchi H, Yukawa H, Hayashi S. Differential ability of somatic stem cells. Cell Transplant. 2009; 18(5):581-9. PMID: 19775520.
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      91. Yukawa H, Mizufune S, Mamori C, Kagami Y, Oishi K, Kaji N, Okamoto Y, Takeshi M, Noguchi H, Baba Y, Hamaguchi M, Hamajima N, Hayashi S. Quantum dots for labeling adipose tissue-derived stem cells. Cell Transplant. 2009; 18(5):591-9. PMID: 19775521.
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      92. Yukawa H, Noguchi H, Oishi K, Inoue M, Hasegawa M, Hamaguchi M, Hamajima N, Hayashi S. Comparison of sendai virus-mediated gene transfer efficiency to adhesive and floating adipose tissue-derived stem cells. Cell Transplant. 2009; 18(5):601-9. PMID: 19775522.
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      93. Yukawa H, Noguchi H, Oishi K, Takagi S, Hamaguchi M, Hamajima N, Hayashi S. Cell transplantation of adipose tissue-derived stem cells in combination with heparin attenuated acute liver failure in mice. Cell Transplant. 2009; 18(5):611-8. PMID: 19775523.
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      94. Yuasa T, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Kubota Y, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Nakaji S, Tanaka N, Kobayashi N. Neovascularization induced around an artificial device implanted in the abdomen by the use of gelatinized fibroblast growth factor 2. Cell Transplant. 2009; 18(5):683-8. PMID: 19775531.
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      95. Noguchi H, Matsumoto S, Onaca N, Naziruddin B, Jackson A, Ikemoto T, Shimoda M, Fujita Y, Chujo D, Iwanaga Y, Nagata H, Okitsu T, Kobayashi N, Ueno H, Chaussabel D, Grayburn P, Banchereau J, Levy MF. Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function. Hum Gene Ther. 2009 Jan; 20(1):73-85. PMID: 18925829.
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      96. Noguchi H, Oishi K, Ueda M, Yukawa H, Hayashi S, Kobayashi N, Levy MF, Matusmoto S. Establishment of mouse pancreatic stem cell line. Cell Transplant. 2009; 18(5):563-71. PMID: 19775518.
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      97. Ikemoto T, Noguchi H, Shimoda M, Naziruddin B, Jackson A, Tamura Y, Fujita Y, Onaca N, Levy MF, Matsumoto S. Islet cell transplantation for the treatment of type 1 diabetes in the USA. J Hepatobiliary Pancreat Surg. 2009; 16(2):118-23. PMID: 19110650.
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      98. Noguchi H, Matsumoto S. Islet transplantation at the Diabetes Research Institute Japan. J Hepatobiliary Pancreat Surg. 2008; 15(3):278-83. PMID: 18535765.
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      99. Navarro-Alvarez N, Rivas-Carrillo JD, Soto-Gutierrez A, Yuasa T, Okitsu T, Noguchi H, Matsumoto S, Takei J, Tanaka N, Kobayashi N. Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplant. 2008; 17(1-2):111-9. PMID: 18468241.
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      100. Liu X, Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Yonekawa Y, Nagata H, Kamiya H, Ueda M, Hatanaka N, Miyakawa S, Kobayashi N, Song C. Analysis of donor- and isolation-related variables from non-heart-beating donors (NHBDs) using the Kyoto islet isolation method. Cell Transplant. 2008; 17(6):649-56. PMID: 18819253.
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      101. Oishi K, Noguchi H, Yukawa H, Miyazaki T, Kato R, Kitagawa Y, Ueda M, Hayashi S. Cryopreservation of mouse adipose tissue-derived stem/progenitor cells. Cell Transplant. 2008; 17(1-2):35-41. PMID: 18468233.
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      102. Yukawa H, Noguchi H, Oishi K, Miyazaki T, Kitagawa Y, Inoue M, Hasegawa M, Hayashi S. Recombinant sendai virus-mediated gene transfer to adipose tissue-derived stem cells (ASCs). Cell Transplant. 2008; 17(1-2):43-50. PMID: 18468234.
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      103. Noguchi H, Ueda M, Hayashi S, Kobayashi N, Okitsu T, Iwanaga Y, Nagata H, Nakai Y, Matsumoto S. Ductal injection of preservation solution increases islet yields in islet isolation and improves islet graft function. Cell Transplant. 2008; 17(1-2):69-81. PMID: 18468237.
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      104. Ueda M, Matsumoto S, Hayashi S, Kobayashi N, Noguchi H. Cell surface heparan sulfate proteoglycans mediate the internalization of PDX-1 protein. Cell Transplant. 2008; 17(1-2):91-7. PMID: 18468239.
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      105. Noguchi H, Yamada Y, Okitsu T, Iwanaga Y, Nagata H, Kobayashi N, Hayashi S, Matsumoto S. Secretory unit of islet in transplantation (SUIT) and engrafted islet rate (EIR) indexes are useful for evaluating single islet transplantation. Cell Transplant. 2008; 17(1-2):121-8. PMID: 18468242.
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      106. Yuasa T, Yamamoto T, Rivas-Carrillo JD, Chen Y, Navarro-Alvarez N, Soto-Guiterrez A, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Laparoscopy-assisted creation of a liver failure model in pigs. Cell Transplant. 2008; 17(1-2):187-93. PMID: 18468249.
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      107. Onaca N, Naziruddin B, Matsumoto S, Noguchi H, Klintmalm GB, Levy MF. Pancreatic islet cell transplantation: update and new developments. Nutr Clin Pract. 2007 Oct; 22(5):485-93. PMID: 17906273.
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      108. Matsumoto S, Noguchi H, Naziruddin B, Onaca N, Jackson A, Nobuyo H, Teru O, Naoya K, Klintmalm G, Levy M. Improvement of pancreatic islet cell isolation for transplantation. Proc (Bayl Univ Med Cent). 2007 Oct; 20(4):357-62. PMID: 17948109; PMCID: PMC2014805.
      109. Noguchi H, Ueda M, Hayashi S, Kobayashi N, Nagata H, Iwanaga Y, Okitsu T, Matsumoto S. Comparison of M-Kyoto solution and histidine-tryptophan-ketoglutarate solution with a trypsin inhibitor for pancreas preservation in islet transplantation. Transplantation. 2007 Sep 15; 84(5):655-8. PMID: 17876281.
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      110. Kaneto H, Miyatsuka T, Fujitani Y, Noguchi H, Song KH, Yoon KH, Matsuoka TA. Role of PDX-1 and MafA as a potential therapeutic target for diabetes. Diabetes Res Clin Pract. 2007 Sep; 77 Suppl 1:S127-37. PMID: 17449132.
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      111. Totsugawa T, Yong C, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Westerman KA, Kohara M, Reth M, Tanaka N, Leboulch P, Kobayashi N. Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination. J Hepatol. 2007 Jul; 47(1):74-82. PMID: 17434229.
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      112. Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May; 56(5):1259-67. PMID: 17287463.
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      113. Soto-Gutierrez A, Navarro-Alvarez N, Rivas-Carrillo JD, Tanaka K, Chen Y, Misawa H, Okitsu T, Noguchi H, Tanaka N, Kobayashi N. Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric. Transplantation. 2007 Jan 27; 83(2):129-37. PMID: 17264808.
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      114. Kim JY, Kina T, Iwanaga Y, Noguchi H, Matsumura K, Hyon SH. Tea polyphenol inhibits allostimulation in mixed lymphocyte culture. Cell Transplant. 2007; 16(1):75-83. PMID: 17436857.
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      115. Noguchi H, Ueda M, Matsumoto S, Kobayashi N, Hayashi S. BETA2/NeuroD protein transduction requires cell surface heparan sulfate proteoglycans. Hum Gene Ther. 2007 Jan; 18(1):10-7. PMID: 17149999.
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      116. Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Liu X, Kamiya H, Ueda M, Hatanaka N, Kobayashi N, Yamada Y, Miyakawa S, Seino Y, Shapiro AM, Tanaka K. Follow-up study of the first successful living donor islet transplantation. Transplantation. 2006 Dec 27; 82(12):1629-33. PMID: 17198249.
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      117. Sato E, Shimomura M, Masuda S, Yano I, Katsura T, Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Inui K. Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation. Drug Metab Pharmacokinet. 2006 Dec; 21(6):492-500. PMID: 17220565.
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      118. Noguchi H. Activation of c-Jun NH2-terminal kinase during islet isolation. Endocr J. 2007 Apr; 54(2):169-76. PMID: 17124365.
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      119. Soto-Gutiérrez A, Kobayashi N, Rivas-Carrillo JD, Navarro-Alvarez N, Zhao D, Zhao D, Okitsu T, Noguchi H, Basma H, Tabata Y, Chen Y, Tanaka K, Narushima M, Miki A, Ueda T, Jun HS, Yoon JW, Lebkowski J, Tanaka N, Fox IJ. Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat Biotechnol. 2006 Nov; 24(11):1412-9. PMID: 17086173.
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      120. Noguchi H. Stem cells for the treatment of diabetes. Endocr J. 2007 Feb; 54(1):7-16. PMID: 17053295.
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      121. Iwanaga Y, Matsumoto S, Okitsu T, Noguchi H, Nagata H, Yonekawa Y, Yamada Y, Fukuda K, Tsukiyama K, Tanaka K. Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant. Ann N Y Acad Sci. 2006 Oct; 1079:335-9. PMID: 17130575.
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      122. Yonekawa Y, Okitsu T, Wake K, Iwanaga Y, Noguchi H, Nagata H, Liu X, Kobayashi N, Matsumoto S. A new mouse model for intraportal islet transplantation with limited hepatic lobe as a graft site. Transplantation. 2006 Sep 15; 82(5):712-5. PMID: 16969298.
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      123. Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Yamada Y, Fukuda K, Shibata T, Kasai Y, Maekawa T, Wada H, Nakamura T, Tanaka K. Successful islet transplantation from nonheartbeating donor pancreata using modified Ricordi islet isolation method. Transplantation. 2006 Aug 27; 82(4):460-5. PMID: 16926588.
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      124. Nagata H, Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Yonekawa Y, Kinukawa T, Shimizu T, Miyakawa S, Shiraki R, Hoshinaga K, Tanaka K. Procurement of the human pancreas for pancreatic islet transplantation from marginal cadaver donors. Transplantation. 2006 Aug 15; 82(3):327-31. PMID: 16906029.
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      125. Ikeda H, Kobayashi N, Tanaka Y, Nakaji S, Yong C, Okitsu T, Oshita M, Matsumoto S, Noguchi H, Narushima M, Tanaka K, Miki A, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Tanaka K, Jun HS, Tanaka N, Yoon JW. A newly developed bioartificial pancreas successfully controls blood glucose in totally pancreatectomized diabetic pigs. Tissue Eng. 2006 Jul; 12(7):1799-809. PMID: 16889510.
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      126. Sassa M, Fukuda K, Fujimoto S, Toyoda K, Fujita Y, Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Ohara T, Okamoto M, Tanaka K, Seino Y, Inagaki N, Yamada Y. A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement. Diabetes Res Clin Pract. 2006 Sep; 73(3):235-40. PMID: 16600414.
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      127. Noguchi H, Matsumoto S, Matsushita M, Kobayashi N, Tanaka K, Matsui H, Tanaka N. Immunosuppression for islet transplantation. Acta Med Okayama. 2006 Apr; 60(2):71-6. PMID: 16680182.
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      128. Fujiwara T, Naomoto Y, Yamatsuji T, Shirakawa Y, Noguchi H, Fujiwara T, Oohara N, Gunduz M, Nagatsuka H, Nishie M, Uetsuka H, Hamazaki S, Tanaka N. Three cases of adenocarcinoma arising in extremely long-segment Barrett's esophagus. Dig Dis Sci. 2006 Mar; 51(3):533-8. PMID: 16614963.
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      129. Tanaka K, Kobayashi N, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Narushima M, Miki A, Okitsu T, Noguchi H, Tanaka N. Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5. Transplantation. 2006 Feb 15; 81(3):427-37. PMID: 16477231.
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      130. Noguchi H, Matsumoto S. Protein transduction technology: a novel therapeutic perspective. Acta Med Okayama. 2006 Feb; 60(1):1-11. PMID: 16508684.
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      131. Izutsu T, Shimotsu S, Matsumoto T, Okada T, Kikuchi A, Kojimoto M, Noguchi H, Yoshikawa K. Deliberate self-harm and childhood hyperactivity in junior high school students. Eur Child Adolesc Psychiatry. 2006 Mar; 15(3):172-6. PMID: 16447027.
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      132. Noguchi H, Matsumoto S. Protein transduction technology offers a novel therapeutic approach for diabetes. J Hepatobiliary Pancreat Surg. 2006; 13(4):306-13. PMID: 16858541.
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      133. Miki A, Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Chen Y, Tanaka K, Narushima M, Tabata Y, Okitsu T, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Maintenance of neovascularization at the implantation site of an artificial device by bFGF and endothelial cell transplant. Cell Transplant. 2006; 15(10):893-901. PMID: 17299994.
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      134. Noguchi H, Xu G, Matsumoto S, Kaneto H, Kobayashi N, Bonner-Weir S, Hayashi S. Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant. 2006; 15(10):929-38. PMID: 17299998.
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      135. Rivas-Carrillo JD, Navarro-Alvarez N, Soto-Gutierrez A, Okitsu T, Chen Y, Tabata Y, Misawa H, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N. Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2. Cell Transplant. 2006; 15(10):939-44. PMID: 17299999.
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      136. Matsumoto S, Noguchi H, Yonekawa Y, Okitsu T, Iwanaga Y, Liu X, Nagata H, Kobayashi N, Ricordi C. Pancreatic islet transplantation for treating diabetes. Expert Opin Biol Ther. 2006 Jan; 6(1):23-37. PMID: 16370912.
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      137. Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JR, Kobayashi E, Tanaka N, Kobayashi N. Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts. Cell Transplant. 2006; 15(4):325-34. PMID: 16898226.
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      138. Noguchi H, Bonner-Weir S, Wei FY, Matsushita M, Matsumoto S. BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence. Diabetes. 2005 Oct; 54(10):2859-66. PMID: 16186386.
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      139. Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H, Lakey JR, Leboulch P, Tanaka N, Yoon JW. A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol. 2005 Oct; 23(10):1274-82. PMID: 16186810.
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      140. Noguchi H, Nakai Y, Matsumoto S, Kawaguchi M, Ueda M, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Minami K, Masui Y, Futaki S, Tanaka K. Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function. Am J Transplant. 2005 Aug; 5(8):1848-55. PMID: 15996231.
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      141. Noguchi H, Matsushita M, Matsumoto S, Lu YF, Matsui H, Bonner-Weir S. Mechanism of PDX-1 protein transduction. Biochem Biophys Res Commun. 2005 Jun 24; 332(1):68-74. PMID: 15896300.
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      142. Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Yamada Y, Fukuda K, Tsukiyama K, Suzuki H, Kawasaki Y, Shimodaira M, Matsuoka K, Shibata T, Kasai Y, Maekawa T, Shapiro J, Tanaka K. Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet. 2005 May 7-13; 365(9471):1642-4. PMID: 15889479.
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      143. Noguchi H, Matsumoto S, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Matsushita M, Wei FY, Matsui H, Minami K, Seino S, Masui Y, Futaki S, Tanaka K. PDX-1 protein is internalized by lipid raft-dependent macropinocytosis. Cell Transplant. 2005; 14(9):637-45. PMID: 16405074.
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      144. Yonekawa Y, Matsumoto S, Okitsu T, Arata T, Iwanaga Y, Noguchi H, Nagata H, O'Neil JJ, Tanaka K. Effective islet isolation method with extremely high islet yields from adult pigs. Cell Transplant. 2005; 14(10):757-62. PMID: 16454350.
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      145. Uetsuka H, Naomoto Y, Fujiwara T, Shirakawa Y, Noguchi H, Yamatsuji T, Haisa M, Matsuoka J, Gunduz M, Takubo K, Tanaka N. Primary malignant melanoma of the esophagus: long-term survival following pre- and postoperative adjuvant hormone/chemotherapy. Dig Dis Sci. 2004 Oct; 49(10):1646-51. PMID: 15573920.
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      146. Matsushita M, Noguchi H, Lu YF, Tomizawa K, Michiue H, Li ST, Hirose K, Bonner-Weir S, Matsui H. Photo-acceleration of protein release from endosome in the protein transduction system. FEBS Lett. 2004 Aug 13; 572(1-3):221-6. PMID: 15304352.
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      147. Shirakawa Y, Naomoto Y, Noma K, Ono R, Nobuhisa T, Kobayashi M, Fujiwara T, Noguchi H, Ohkawa T, Yamatsuji T, Haisa M, Matsuoka J, Gunduz M, Tanaka N. Free jejunal graft for hypopharyngeal and esophageal reconstruction. Langenbecks Arch Surg. 2004 Oct; 389(5):387-90. PMID: 15605170.
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      148. Matsumura T, Takesue M, Westerman KA, Okitsu T, Sakaguchi M, Fukazawa T, Totsugawa T, Noguchi H, Yamamoto S, Stolz DB, Tanaka N, Leboulch P, Kobayashi N. Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT. Transplantation. 2004 May 15; 77(9):1357-65. PMID: 15167590.
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      149. Noguchi H, Matsushita M, Okitsu T, Moriwaki A, Tomizawa K, Kang S, Li ST, Kobayashi N, Matsumoto S, Tanaka K, Tanaka N, Matsui H. A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat Med. 2004 Mar; 10(3):305-9. PMID: 14770176.
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      150. Matsumoto H, Tanaka K, Noguchi H, Hayakawa Y. Cause of mortality in insects under severe stress. Eur J Biochem. 2003 Aug; 270(16):3469-76. PMID: 12899705.
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      151. Noguchi H, Kaneto H, Weir GC, Bonner-Weir S. PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells. Diabetes. 2003 Jul; 52(7):1732-7. PMID: 12829640.
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      152. Watanabe T, Shibata N, Westerman KA, Okitsu T, Allain JE, Sakaguchi M, Totsugawa T, Maruyama M, Matsumura T, Noguchi H, Yamamoto S, Hikida M, Ohmori A, Reth M, Weber A, Tanaka N, Leboulch P, Kobayashi N. Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers. Transplantation. 2003 Jun 15; 75(11):1873-80. PMID: 12811248.
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      153. Kobayashi O, Sakaguchi M, Okitsu T, Totsugawa T, Maruyama M, Matsumura T, Watanabe T, Noguchi H, Kosaka Y, Fujiwara T, Tanaka N. Improvement in the differentiated hepatic phenotype of immortalized human hepatocytes by adenovirus mediated p21 gene transfer. ASAIO J. 2002 Jul-Aug; 48(4):355-9. PMID: 12141463.
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      154. Noguchi H, Kobayashi N, Westerman KA, Sakaguchi M, Okitsu T, Totsugawa T, Watanabe T, Matsumura T, Fujiwara T, Ueda T, Miyazaki M, Tanaka N, Leboulch P. Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization. Hum Gene Ther. 2002 Jan 20; 13(2):321-34. PMID: 11812287.
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      155. Kunieda T, Kobayashi N, Sakaguchi M, Okitsu T, Totsugawa T, Watanabe T, Matsumura T, Maruyama M, Noguchi H, Takesue M, Shibata N, Ohmoto K, Fujiwara T, Yamamoto S, Tanaka N. Transduction of immortalized human hepatocytes with p21 to enhance differentiated phenotypes. Cell Transplant. 2002; 11(5):421-8. PMID: 12382668.
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      156. Totsugawa T, Kobayashi N, Okitsu T, Noguchi H, Watanabe T, Matsumura T, Maruyama M, Fujiwara T, Sakaguchi M, Tanaka N. Lentiviral transfer of the LacZ gene into human endothelial cells and human bone marrow mesenchymal stem cells. Cell Transplant. 2002; 11(5):481-8. PMID: 12382678.
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      157. Arikura J, Kobayashi N, Okitsu T, Noguchi H, Totsugawa T, Watanabe T, Matsumura T, Maruyama M, Kosaka Y, Tanaka N, Onodera K, Kasai S. UW solution: a promising tool for cryopreservation of primarily isolated rat hepatocytes. J Hepatobiliary Pancreat Surg. 2002; 9(6):742-9. PMID: 12658410.
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