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    Hyunil Jo, PhD

    TitleSpecialist
    SchoolUCSF School of Pharmacy
    DepartmentPharmaceutical Chemistry
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
    Phone215-913-7838
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      Collapse Biography 
      Collapse Education and Training
      Seoul National UniversityB.S.Pharmacy2001
      Seoul National UniversityM.S.Pharmacy2003
      University of PennsylvaniaPh.D.Chemistry2008
      Collapse Awards and Honors
      Department of Defense2005 - 2008Predoctoral Training Award for Prostate Cancer

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M. Structural Polymorphism of Alzheimer's ß-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. J Am Chem Soc. 2016 Aug 10; 138(31):9840-52. PMID: 27414264.
        View in: PubMed
      2. To TL, Medzihradszky KF, Burlingame AL, DeGrado WF, Jo H, Shu X. Photoactivatable protein labeling by singlet oxygen mediated reactions. Bioorg Med Chem Lett. 2016 Jul 15; 26(14):3359-63. PMID: 27220724.
        View in: PubMed
      3. Reed NI, Jo H, Chen C, Tsujino K, Arnold TD, DeGrado WF, Sheppard D. The avß1 integrin plays a critical in vivo role in tissue fibrosis. Sci Transl Med. 2015 May 20; 7(288):288ra79. PMID: 25995225; PMCID: PMC4461057.
      4. Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF. Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel. J Am Chem Soc. 2014 Dec 31; 136(52):17987-95. PMID: 25470189; PMCID: PMC4286326.
      5. Markiewicz BN, Jo H, Culik RM, DeGrado WF, Gai F. Assessment of local friction in protein folding dynamics using a helix cross-linker. J Phys Chem B. 2013 Nov 27; 117(47):14688-96. PMID: 24205975; PMCID: PMC3904762.
      6. Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF. Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus. J Med Chem. 2013 Apr 11; 56(7):2804-12. PMID: 23437766; PMCID: PMC4036227.
      7. Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, Sinnis P, Scott RW, Greenbaum DC. Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host Microbe. 2012 Dec 13; 12(6):815-23. PMID: 23245326; PMCID: PMC3638032.
      8. Jo H, Meinhardt N, Wu Y, Kulkarni S, Hu X, Low KE, Davies PL, DeGrado WF, Greenbaum DC. Development of a-helical calpain probes by mimicking a natural protein-protein interaction. J Am Chem Soc. 2012 Oct 24; 134(42):17704-13. PMID: 22998171; PMCID: PMC3523126.
      9. Reig AJ, Pires MM, Snyder RA, Wu Y, Jo H, Kulp DW, Butch SE, Calhoun JR, Szyperski T, Szyperski TG, Solomon EI, DeGrado WF. Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins. Nat Chem. 2012 Nov; 4(11):900-6. PMID: 23089864; PMCID: PMC3568993.
      10. Culik RM, Jo H, DeGrado WF, Gai F. Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in ß-sheet folding. J Am Chem Soc. 2012 May 16; 134(19):8026-9. PMID: 22540162; PMCID: PMC3354031.
      11. Borza CM, Su Y, Chen X, Yu L, Mont S, Chetyrkin S, Voziyan P, Hudson BG, Billings PC, Jo H, Bennett JS, Degrado WF, Eckes B, Zent R, Pozzi A. Inhibition of integrin a2ß1 ameliorates glomerular injury. J Am Soc Nephrol. 2012 Jun; 23(6):1027-38. PMID: 22440900; PMCID: PMC3358756.
      12. Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Affinity of talin-1 for the ß3-integrin cytosolic domain is modulated by its phospholipid bilayer environment. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):793-8. PMID: 22210111; PMCID: PMC3271903.
      13. Jo H, Culik RM, Korendovych IV, Degrado WF, Gai F. Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation. Biochemistry. 2010 Dec 14; 49(49):10354-6. PMID: 21077670; PMCID: PMC2999665.
      14. Lucumi E, Darling C, Jo H, Napper AD, Chandramohanadas R, Fisher N, Shone AE, Jing H, Ward SA, Biagini GA, DeGrado WF, Diamond SL, Greenbaum DC. Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrob Agents Chemother. 2010 Sep; 54(9):3597-604. PMID: 20547797; PMCID: PMC2934977.
      15. Jo H, Fitzgerald ME, Winkler JD. An unusual pathway to cyclobutane formation via desulfurative intramolecular photocycloaddition of an enone benzothiazoline pair. Org Lett. 2009 Apr 16; 11(8):1685-7. PMID: 19301922.
        View in: PubMed
      16. Baek S, Jo H, Kim H, Kim H, Kim S, Kim D. Highly stereoselective and efficient total synthesis of (+)-laurencin. Org Lett. 2005 Jan 6; 7(1):75-7. PMID: 15624981.
        View in: PubMed
      17. Kim D, Lee J, Shim PJ, Lim JI, Jo H, Kim S. Asymmetric total synthesis of (+)-brefeldin A from (S)-lactate by triple chirality transfer process and nitrile oxide cycloaddition. J Org Chem. 2002 Feb 8; 67(3):764-71. PMID: 11856018.
        View in: PubMed
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