Ian Welsh, PhD
|School||UCSF School of Dentistry|
|Address||401 Parnassus Ave, LangPorter|
San Francisco CA 94143
Morphogenesis represents a critical and dynamic utilization of genomic information in the life history of an organism, and thus a powerful system for advancing our understanding of genome regulation and function. My work focuses on the establishment and characterization genetic models of embryonic morphogenesis as a means to advance a more quantitative understanding of genome function. The goal of my research is to elucidate the cis-, trans-, and higher order basis of genomic information processing in the context of developing embryos. This processing occurs via the dynamics of transcriptional regulation and intercellular signaling, and is critical for coordinating morphogenic cellular behavior. I am leveraging genome wide approaches and developmental genetics to characterize both evolutionary and pathological variation in regulatory networks controlling morphogenesis along the anterior-posterior axis of the upper jaw.
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