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India Hook-Barnard, PhD

TitleDirector of Research Strategy
SchoolUCSF Chancellor/EVC/FAS
DepartmentVC Science Policy & Strategy
Address600 16th St
San Francisco CA 94143
Phone415-476-8039
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    TitleAssociate Director of Precision Medicine


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    Dr. Hook-Barnard is Director of Research Strategy and Associate Director, Precision Medicine. She serves as director of the UCSF Precision Medicine Platform Committee, which aims to conceptualize and build precision medicine as a central overarching institutional vision at UCSF. She helped launch and continues to partner with the California Initiative for Advancing Precision Medicine (CIAPM) to help advance the state-wide initiative.

    In the UCSF Office of Science Policy and Strategy and the School of Medicine Dean’s Office, she works with scientific experts and leaders from across academia, industry, and government sectors to identify and frame scientific opportunities, technical feasibility, and organizational challenges. She develops and supports efforts to secure major research and infrastructure funding, supports research and graduate programs (such as SOM Bridge Funding, and the Integrated Funding Model (IFM)), and provides advice, consultation, and analysis on scientific initiatives.

    Dr. Hook-Barnard’s primary interests are in areas of emerging science, technology, and medicine, spanning fundamental discovery to translational application, clinical practice, and population health research, including issues of policy, regulation, ethical and societal concerns, and workforce. From 2008- 2015, she worked as a senior program officer with the National Academy of Sciences (NAS) and the Institute of Medicine’s (IOM). At the NAS and IOM, she developed and administered a variety of programs, working with academic faculty, scientists, engineers, clinicians, business leaders and policy experts. She served as the study director for six National Academies reports, including: Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease (2011), Determining Core Capabilities in Chemical and Biological Defense Science and Technology (2012) and Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk (2015.)

    Dr. Hook-Barnard was a postdoctoral research fellow at the National Institutes of Health. She earned her PhD in Microbiology-Medicine from the Department of Molecular Microbiology and Immunology at the University of Missouri.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hawgood S, Hook-Barnard I, O'Brien TC, Yamamoto KR. Precision medicine: Beyond the inflection point. Sci Transl Med. 2015 Aug 12; 7(300):300ps17. PMID: 26268311.
      View in: PubMed
    2. Hook-Barnard I, Hinton DM. The promoter spacer influences transcription initiation via sigma70 region 1.1 of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A. 2009 Jan 20; 106(3):737-42. PMID: 19139410; PMCID: PMC2630097.
    3. Hook-Barnard I, Brickman TJ, McIntosh MA. Identification of an AU-rich translational enhancer within the Escherichia coli fepB leader RNA. J Bacteriol. 2007 Jun; 189(11):4028-37. PMID: 17400738; PMCID: PMC1913407.
    4. Hook-Barnard I, Hinton DM. Transcription initiation by mix and match elements: flexibility for polymerase binding to bacterial promoters. Gene Regul Syst Bio. 2007; 1:275-93. PMID: 19119427; PMCID: PMC2613000.
    5. Hook-Barnard I, Johnson XB, Hinton DM. Escherichia coli RNA polymerase recognition of a sigma70-dependent promoter requiring a -35 DNA element and an extended -10 TGn motif. J Bacteriol. 2006 Dec; 188(24):8352-9. PMID: 17012380; PMCID: PMC1698240.
    6. Hinton DM, Pande S, Wais N, Johnson XB, Vuthoori M, Makela A, Hook-Barnard I. Transcriptional takeover by sigma appropriation: remodelling of the sigma70 subunit of Escherichia coli RNA polymerase by the bacteriophage T4 activator MotA and co-activator AsiA. Microbiology. 2005 Jun; 151(Pt 6):1729-40. PMID: 15941982.
      View in: PubMed
    7. Furrer JL, Sanders DN, Hook-Barnard I, McIntosh MA. Export of the siderophore enterobactin in Escherichia coli: involvement of a 43 kDa membrane exporter. Mol Microbiol. 2002 Jun; 44(5):1225-34. PMID: 12068807.
      View in: PubMed
    8. Christoffersen CA, Brickman TJ, Hook-Barnard I, McIntosh MA. Regulatory architecture of the iron-regulated fepD-ybdA bidirectional promoter region in Escherichia coli. J Bacteriol. 2001 Mar; 183(6):2059-70. PMID: 11222606; PMCID: PMC95103.
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