India Hook-Barnard, PhD

TitleDirector of Research Strategy
SchoolUCSF School of Medicine
DepartmentDean's Office
Address600 16th St
San Francisco CA 94158
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    India joined UCSF in February of 2015 as Director of Research Strategy and Associate Director of Precision Medicine, where she works closely with Vice Chancellor for Science Policy and Strategy and Vice Dean for Research (School of Medicine) Keith Yamamoto, PhD developing and supporting research and research training programs.

    India works closely with Keith Yamamoto on many efforts including developing and supporting research and research training programs, directing efforts to secure major research and infrastructure funding, and providing advice, consultation and analysis on scientific initiatives. In her role she manages the Bridge Funding program and the Integrated Funding Model. Additionally, she also works with Yamamoto in his role as Vice Chancellor for Science Policy and Strategy, supporting basic, clinical and social and behavioral research development and the pursuit of precision medicine, the over-arching conceptual and organizational platform for research on our campus.

    India's background in research strategy includes a wide spectrum of scientific discovery, translational research and clinical medicine, as well as policy, regulation, ethical and societal concerns. Since 2008, she has worked with the National Academies, first as a senior program officer with the National Academy of Sciences (NAS) Board on Life Sciences and most recently as a senior program officer at the Institute of Medicine’s (IOM) Board on Health Sciences Policy. At the NAS and IOM, she developed and administered programs, working with boards and committees comprised of distinguished academic faculty, scientists, engineers, clinicians, business leaders and policy experts.

    Hook-Barnard served as the study director for six National Academies reports, including the pivotal Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease, co-chaired by then UCSF chancellor Sue Desmond-Hellmann, with Drs. Keith Yamamoto and Bernard Lo among its committee members. Most recently, she directed the just released IOM report Sharing Clinical Trial Data, chaired by Dr. Bernard Lo, with Dr. Ida Sim among the committee members.

    She earned a PhD in microbiology (medicine) at University of Missouri and was a postdoctoral fellow at the NIH.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hawgood S, Hook-Barnard I, O'Brien TC, Yamamoto KR. Precision medicine: Beyond the inflection point. Sci Transl Med. 2015 Aug 12; 7(300):300ps17. PMID: 26268311.
      View in: PubMed
    2. Hook-Barnard I, Hinton DM. The promoter spacer influences transcription initiation via sigma70 region 1.1 of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A. 2009 Jan 20; 106(3):737-42. PMID: 19139410; PMCID: PMC2630097.
    3. Hook-Barnard I, Brickman TJ, McIntosh MA. Identification of an AU-rich translational enhancer within the Escherichia coli fepB leader RNA. J Bacteriol. 2007 Jun; 189(11):4028-37. PMID: 17400738; PMCID: PMC1913407.
    4. Hook-Barnard I, Hinton DM. Transcription initiation by mix and match elements: flexibility for polymerase binding to bacterial promoters. Gene Regul Syst Bio. 2007; 1:275-93. PMID: 19119427; PMCID: PMC2613000.
    5. Hook-Barnard I, Johnson XB, Hinton DM. Escherichia coli RNA polymerase recognition of a sigma70-dependent promoter requiring a -35 DNA element and an extended -10 TGn motif. J Bacteriol. 2006 Dec; 188(24):8352-9. PMID: 17012380; PMCID: PMC1698240.
    6. Hinton DM, Pande S, Wais N, Johnson XB, Vuthoori M, Makela A, Hook-Barnard I. Transcriptional takeover by sigma appropriation: remodelling of the sigma70 subunit of Escherichia coli RNA polymerase by the bacteriophage T4 activator MotA and co-activator AsiA. Microbiology. 2005 Jun; 151(Pt 6):1729-40. PMID: 15941982.
      View in: PubMed
    7. Furrer JL, Sanders DN, Hook-Barnard I, McIntosh MA. Export of the siderophore enterobactin in Escherichia coli: involvement of a 43 kDa membrane exporter. Mol Microbiol. 2002 Jun; 44(5):1225-34. PMID: 12068807.
      View in: PubMed
    8. Christoffersen CA, Brickman TJ, Hook-Barnard I, McIntosh MA. Regulatory architecture of the iron-regulated fepD-ybdA bidirectional promoter region in Escherichia coli. J Bacteriol. 2001 Mar; 183(6):2059-70. PMID: 11222606; PMCID: PMC95103.
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