Ira Mellman, PhD

Title(s)Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
AddressLocation Required, #001
Varies CA 00000
Phone--
ORCID ORCID Icon0000-0002-6132-7299 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Yale University School of Medicine, New Haven, CTPhDGenetics
    The Rockefeller University, New York, NYpostdocImmunology/Cell Biology
    Oberlin College, Oberlin, OHAB

    Collapse Research 
    Collapse Research Activities and Funding
    Cell Biology of the Immune Response
    NIH R13AI053905Jan 15, 2003 - Dec 31, 2003
    Role: Principal Investigator
    GORDON RESEARCH CONFERENCE ON MOLECULAR MEMBRANE BIOLOGY
    NIH R13GM049679Jul 1, 1993 - Jun 30, 1994
    Role: Principal Investigator
    DEVELOPMENTAL CELL BIOLOGY OF DENDRITIC CELLS
    NIH R37AI034098Mar 1, 1993 - Jul 31, 2008
    Role: Principal Investigator
    CELL BIOLOGY OF FC RECEPTOR FUNCTION
    NIH R01AI034098Mar 1, 1993 - Feb 28, 1998
    Role: Principal Investigator
    CELL BIOLOGY OF MHC CLASS II ANTIGEN PRESENTATION
    NIH R01GM033904Jul 1, 1984 - Mar 31, 1999
    Role: Principal Investigator
    Molecular Sorting During Intracellular Transport
    NIH R01GM029765Jul 1, 1981 - Dec 30, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity. Cancer Immunol Res. 2024 Mar 18. Lim J, Rodriguez R, Williams K, Silva J, Gutierrez AG, Tyler P, Baharom F, Sun T, Lin E, Martin S, Kayser BD, Johnston RJ, Mellman I, Delamarre L, West NR, Müller S, Qu Y, Heger K. PMID: 38489753.
      View in: PubMed   Mentions:    Fields:    
    2. Publisher Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells. Nature. 2024 Mar 13. Guan X, Hu R, Choi Y, Srivats S, Nabet BY, Silva J, McGinnis L, Hendricks R, Nutsch K, Banta KL, Duong E, Dunkle A, Chang PS, Han CJ, Mittman S, Molden N, Daggumati P, Connolly W, Johnson M, Abreu DR, Cho BC, Italiano A, Gil-Bazo I, Felip E, Mellman I, Mariathasan S, Shames DS, Meng R, Chiang EY, Johnston RJ, Patil NS. PMID: 38480897.
      View in: PubMed   Mentions:    Fields:    
    3. Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells. Nature. 2024 Feb 28. Guan X, Hu R, Choi Y, Srivats S, Nabet BY, Silva J, McGinnis L, Hendricks R, Nutsch K, Banta KL, Duong E, Dunkle A, Chang PS, Han CJ, Mittman S, Molden N, Daggumati P, Connolly W, Johnson M, Abreu DR, Cho BC, Italiano A, Gil-Bazo I, Felip E, Mellman I, Mariathasan S, Shames DS, Meng R, Chiang EY, Johnston RJ, Patil NS. PMID: 38418879.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Immunomodulatory effects and improved outcomes with cisplatin- versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer. Cell Rep Med. 2024 Feb 20; 5(2):101393. Galsky MD, Guan X, Rishipathak D, Rapaport AS, Shehata HM, Banchereau R, Yuen K, Varfolomeev E, Hu R, Han CJ, Li H, Liang Y, Vucic D, Wang L, Zhu J, Yu H, Herbst RH, Hajaj E, Kiner E, Bamias A, De Santis M, Davis ID, Arranz JÁ, Kikuchi E, Bernhard S, Williams P, Lee C, Mellman I, Sanjabi S, Johnston R, Black PC, Grande E, Mariathasan S. PMID: 38280376; PMCID: PMC10897541.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage. J Exp Med. 2024 Feb 05; 221(2). Tong AJ, Leylek R, Herzner AM, Rigas D, Wichner S, Blanchette C, Tahtinen S, Kemball CC, Mellman I, Haley B, Freund EC, Delamarre L. PMID: 38095631; PMCID: PMC10720541.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. The cancer-immunity cycle: Indication, genotype, and immunotype. Immunity. 2023 10 10; 56(10):2188-2205. Mellman I, Chen DS, Powles T, Turley SJ. PMID: 37820582.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    7. Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors. Nat Commun. 2023 08 05; 14(1):4703. Castiglioni A, Yang Y, Williams K, Gogineni A, Lane RS, Wang AW, Shyer JA, Zhang Z, Mittman S, Gutierrez A, Astarita JL, Thai M, Hung J, Yang YA, Pourmohamad T, Himmels P, De Simone M, Elstrott J, Capietto AH, Cubas R, Modrusan Z, Sandoval W, Ziai J, Gould SE, Fu W, Wang Y, Koerber JT, Sanjabi S, Mellman I, Turley SJ, Müller S. PMID: 37543621; PMCID: PMC10404279.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. In situ tumour arrays reveal early environmental control of cancer immunity. Nature. 2023 Jun; 618(7966):827-833. Ortiz-Muñoz G, Brown M, Carbone CB, Pechuan-Jorge X, Rouilly V, Lindberg H, Ritter AT, Raghupathi G, Sun Q, Nicotra T, Mantri SR, Yang A, Doerr J, Nagarkar D, Darmanis S, Haley B, Mariathasan S, Wang Y, Gomez-Roca C, de Andrea CE, Spigel D, Wu T, Delamarre L, Schöneberg J, Modrusan Z, Price R, Turley SJ, Mellman I, Moussion C. PMID: 37258670; PMCID: PMC10284705.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature. 2023 Jun; 618(7963):144-150. Rojas LA, Sethna Z, Soares KC, Olcese C, Pang N, Patterson E, Lihm J, Ceglia N, Guasp P, Chu A, Yu R, Chandra AK, Waters T, Ruan J, Amisaki M, Zebboudj A, Odgerel Z, Payne G, Derhovanessian E, Müller F, Rhee I, Yadav M, Dobrin A, Sadelain M, Luksza M, Cohen N, Tang L, Basturk O, Gönen M, Katz S, Do RK, Epstein AS, Momtaz P, Park W, Sugarman R, Varghese AM, Won E, Desai A, Wei AC, D'Angelica MI, Kingham TP, Mellman I, Merghoub T, Wolchok JD, Sahin U, Türeci Ö, Greenbaum BD, Jarnagin WR, Drebin J, O'Reilly EM, Balachandran VP. PMID: 37165196; PMCID: PMC10171177.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCellsCTClinical Trials
    10. CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy. Cell Rep Med. 2023 01 17; 4(1):100878. Huseni MA, Wang L, Klementowicz JE, Yuen K, Breart B, Orr C, Liu LF, Li Y, Gupta V, Li C, Rishipathak D, Peng J, Senbabaoglu Y, Modrusan Z, Keerthivasan S, Madireddi S, Chen YJ, Fraser EJ, Leng N, Hamidi H, Koeppen H, Ziai J, Hashimoto K, Fassò M, Williams P, McDermott DF, Rosenberg JE, Powles T, Emens LA, Hegde PS, Mellman I, Turley SJ, Wilson MS, Mariathasan S, Molinero L, Merchant M, West NR. PMID: 36599350; PMCID: PMC9873827.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    11. NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer. Cancer Cell. 2022 09 12; 40(9):1027-1043.e9. Salomé B, Sfakianos JP, Ranti D, Daza J, Bieber C, Charap A, Hammer C, Banchereau R, Farkas AM, Ruan DF, Izadmehr S, Geanon D, Kelly G, de Real RM, Lee B, Beaumont KG, Shroff S, Wang YA, Wang YC, Thin TH, Garcia-Barros M, Hegewisch-Solloa E, Mace EM, Wang L, O'Donnell T, Chowell D, Fernandez-Rodriguez R, Skobe M, Taylor N, Kim-Schulze S, Sebra RP, Palmer D, Clancy-Thompson E, Hammond S, Kamphorst AO, Malmberg KJ, Marcenaro E, Romero P, Brody R, Viard M, Yuki Y, Martin M, Carrington M, Mehrazin R, Wiklund P, Mellman I, Mariathasan S, Zhu J, Galsky MD, Bhardwaj N, Horowitz A. PMID: 36099881; PMCID: PMC9479122.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    12. Coming of Age: Human Genomics and the Cancer-Immune Set Point. Cancer Immunol Res. 2022 06 03; 10(6):674-679. Hammer C, Mellman I. PMID: 35471657.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation. J Cell Biol. 2022 06 06; 221(6). Guttman O, Le Thomas A, Marsters S, Lawrence DA, Gutgesell L, Zuazo-Gaztelu I, Harnoss JM, Haag SM, Murthy A, Strasser G, Modrusan Z, Wu T, Mellman I, Ashkenazi A. PMID: 35446348; PMCID: PMC9036094.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    14. ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack. Science. 2022 04 22; 376(6591):377-382. Ritter AT, Shtengel G, Xu CS, Weigel A, Hoffman DP, Freeman M, Iyer N, Alivodej N, Ackerman D, Voskoboinik I, Trapani J, Hess HF, Mellman I. PMID: 35446649.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    15. Allelic variation in HLA-DRB1 is associated with development of antidrug antibodies in cancer patients treated with atezolizumab that are neutralizing in vitro. Clin Transl Sci. 2022 06; 15(6):1393-1399. Hammer C, Ruppel J, Kamen L, Hunkapiller J, Mellman I, Quarmby V. PMID: 35263013; PMCID: PMC9199883.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy. J Immunother Cancer. 2022 04; 10(4). Chiang EY, Mellman I. PMID: 35379739; PMCID: PMC8981293.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    17. IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines. Nat Immunol. 2022 04; 23(4):532-542. Tahtinen S, Tong AJ, Himmels P, Oh J, Paler-Martinez A, Kim L, Wichner S, Oei Y, McCarron MJ, Freund EC, Amir ZA, de la Cruz CC, Haley B, Blanchette C, Schartner JM, Ye W, Yadav M, Sahin U, Delamarre L, Mellman I. PMID: 35332327.
      View in: PubMed   Mentions: 102     Fields:    Translation:Animals
    18. Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity. Nat Immunol. 2022 04; 23(4):568-580. Barreira da Silva R, Leitao RM, Pechuan-Jorge X, Werneke S, Oeh J, Javinal V, Wang Y, Phung W, Everett C, Nonomiya J, Arnott D, Lu C, Hsiao YC, Koerber JT, Hötzel I, Ziai J, Modrusan Z, Pillow TH, Roose-Girma M, Schartner JM, Merchant M, Rutz S, Eidenschenk C, Mellman I, Albert ML. PMID: 35314846.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses. Immunity. 2022 03 08; 55(3):512-526.e9. Banta KL, Xu X, Chitre AS, Au-Yeung A, Takahashi C, O'Gorman WE, Wu TD, Mittman S, Cubas R, Comps-Agrar L, Fulzele A, Bennett EJ, Grogan JL, Hui E, Chiang EY, Mellman I. PMID: 35263569; PMCID: PMC9287124.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    20. Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification. Cancer Cell. 2021 12 13; 39(12):1594-1609.e12. Leader AM, Grout JA, Maier BB, Nabet BY, Park MD, Tabachnikova A, Chang C, Walker L, Lansky A, Le Berichel J, Troncoso L, Malissen N, Davila M, Martin JC, Magri G, Tuballes K, Zhao Z, Petralia F, Samstein R, D'Amore NR, Thurston G, Kamphorst AO, Wolf A, Flores R, Wang P, Müller S, Mellman I, Beasley MB, Salmon H, Rahman AH, Marron TU, Kenigsberg E, Merad M. PMID: 34767762; PMCID: PMC8728963.
      View in: PubMed   Mentions: 94     Fields:    Translation:Humans
    21. Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues. Nature. 2021 Nov; 599(7885):E5. Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, Walther TC, Farese RV, Lippincott-Schwartz J, Mellman I, Solimena M, Hess HF. PMID: 34732896.
      View in: PubMed   Mentions:    Fields:    
    22. An open-access volume electron microscopy atlas of whole cells and tissues. Nature. 2021 11; 599(7883):147-151. Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, Walther TC, Farese RV, Lippincott-Schwartz J, Mellman I, Solimena M, Hess HF. PMID: 34616045; PMCID: PMC9004664.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    23. Molecular determinants of response to PD-L1 blockade across tumor types. Nat Commun. 2021 06 25; 12(1):3969. Banchereau R, Leng N, Zill O, Sokol E, Liu G, Pavlick D, Maund S, Liu LF, Kadel E, Baldwin N, Jhunjhunwala S, Nickles D, Assaf ZJ, Bower D, Patil N, McCleland M, Shames D, Molinero L, Huseni M, Sanjabi S, Cummings C, Mellman I, Mariathasan S, Hegde P, Powles T. PMID: 34172722; PMCID: PMC8233428.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCTClinical Trials
    24. Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun. 2021 06 07; 12(1):3355. Khan Z, Hammer C, Carroll J, Di Nucci F, Acosta SL, Maiya V, Bhangale T, Hunkapiller J, Mellman I, Albert ML, McCarthy MI, Chandler GS. PMID: 34099659; PMCID: PMC8184890.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    25. Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues. Nat Immunol. 2021 05; 22(5):571-585. Kapoor VN, Müller S, Keerthivasan S, Brown M, Chalouni C, Storm EE, Castiglioni A, Lane R, Nitschke M, Dominguez CX, Astarita JL, Krishnamurty AT, Carbone CB, Senbabaoglu Y, Wang AW, Wu X, Cremasco V, Roose-Girma M, Tam L, Doerr J, Chen MZ, Lee WP, Modrusan Z, Yang YA, Bourgon R, Sandoval W, Shaw AS, de Sauvage FJ, Mellman I, Moussion C, Turley SJ. PMID: 33903764.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    26. Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade. J Immunother Cancer. 2021 04; 9(4). Banchereau R, Chitre AS, Scherl A, Wu TD, Patil NS, de Almeida P, Kadel Iii EE, Madireddi S, Au-Yeung A, Takahashi C, Chen YJ, Modrusan Z, McBride J, Nersesian R, El-Gabry EA, Robida MD, Hung JC, Kowanetz M, Zou W, McCleland M, Caplazi P, Eshgi ST, Koeppen H, Hegde PS, Mellman I, Mathews WR, Powles T, Mariathasan S, Grogan J, O'Gorman WE. PMID: 33827905; PMCID: PMC8032254.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    27. Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). Zhou Y, Bastian IN, Long MD, Dow M, Li W, Liu T, Ngu RK, Antonucci L, Huang JY, Phung QT, Zhao XH, Banerjee S, Lin XJ, Wang H, Dang B, Choi S, Karin D, Su H, Ellisman MH, Jamieson C, Bosenberg M, Cheng Z, Haybaeck J, Kenner L, Fisch KM, Bourgon R, Hernandez G, Lill JR, Liu S, Carter H, Mellman I, Karin M, Shalapour S. PMID: 33602823; PMCID: PMC7923353.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    28. Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers. J Exp Med. 2021 01 04; 218(1). Byrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Mellman I, Duffy D, Albert ML, Milieu Intérieur Consortium. PMID: 33175106; PMCID: PMC7664509.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCellsCTClinical Trials
    29. Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation. PLoS One. 2020; 15(11):e0238484. Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I. PMID: 33232321; PMCID: PMC7685505.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    30. PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer. Nat Cancer. 2020 07; 1(7):681-691. Oh SA, Wu DC, Cheung J, Navarro A, Xiong H, Cubas R, Totpal K, Chiu H, Wu Y, Comps-Agrar L, Leader AM, Merad M, Roose-Germa M, Warming S, Yan M, Kim JM, Rutz S, Mellman I. PMID: 35122038.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansCells
    31. Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12288-12294. Khan Z, Di Nucci F, Kwan A, Hammer C, Mariathasan S, Rouilly V, Carroll J, Fontes M, Ley Acosta S, Guardino E, Chen-Harris H, Bhangale T, Mellman I, Rosenberg J, Powles T, Hunkapiller J, Chandler GS, Albert ML. PMID: 32430334; PMCID: PMC7275757.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    32. Dexamethasone premedication suppresses vaccine-induced immune responses against cancer. Oncoimmunology. 2020 05 13; 9(1):1758004. Vormehr M, Lehar S, Kranz LM, Tahtinen S, Oei Y, Javinal V, Delamarre L, Walzer KC, Diken M, Kreiter S, Mellman I, Sahin U, Schartner JM, Türeci Ö. PMID: 32923115; PMCID: PMC7458619.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    33. Mutation position is an important determinant for predicting cancer neoantigens. J Exp Med. 2020 04 06; 217(4). Capietto AH, Jhunjhunwala S, Pollock SB, Lupardus P, Wong J, Hänsch L, Cevallos J, Chestnut Y, Fernandez A, Lounsbury N, Nozawa T, Singh M, Fan Z, de la Cruz CC, Phung QT, Taraborrelli L, Haley B, Lill JR, Mellman I, Bourgon R, Delamarre L. PMID: 31940002; PMCID: PMC7144530.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    34. Peripheral T cell expansion predicts tumour infiltration and clinical response. Nature. 2020 03; 579(7798):274-278. Wu TD, Madireddi S, de Almeida PE, Banchereau R, Chen YJ, Chitre AS, Chiang EY, Iftikhar H, O'Gorman WE, Au-Yeung A, Takahashi C, Goldstein LD, Poon C, Keerthivasan S, de Almeida Nagata DE, Du X, Lee HM, Banta KL, Mariathasan S, Das Thakur M, Huseni MA, Ballinger M, Estay I, Caplazi P, Modrusan Z, Delamarre L, Mellman I, Bourgon R, Grogan JL. PMID: 32103181.
      View in: PubMed   Mentions: 286     Fields:    Translation:HumansCells
    35. Transposable element expression in tumors is associated with immune infiltration and increased antigenicity. Nat Commun. 2019 11 19; 10(1):5228. Kong Y, Rose CM, Cass AA, Williams AG, Darwish M, Lianoglou S, Haverty PM, Tong AJ, Blanchette C, Albert ML, Mellman I, Bourgon R, Greally J, Jhunjhunwala S, Chen-Harris H. PMID: 31745090; PMCID: PMC6864081.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    36. E-Cadherin is Dispensable to Maintain Langerhans Cells in the Epidermis. J Invest Dermatol. 2020 01; 140(1):132-142.e3. Brand A, Diener N, Zahner SP, Tripp C, Backer RA, Karram K, Jiang A, Mellman I, Stoitzner P, Clausen BE. PMID: 31260672.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    37. Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models. Cancer Immunol Res. 2019 06; 7(6):963-976. Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, Mellman I, Cubas R. PMID: 31064777.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    38. The Dendritic Cell Strikes Back. Immunity. 2019 02 19; 50(2):533. Moussion C, Mellman I. PMID: 30784580.
      View in: PubMed   Mentions: 1     Fields:    
    39. The Dendritic Cell Strikes Back. Immunity. 2018 12 18; 49(6):997-999. Moussion C, Mellman I. PMID: 30566889.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    40. Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11701-E11710. Lim YW, Chen-Harris H, Mayba O, Lianoglou S, Wuster A, Bhangale T, Khan Z, Mariathasan S, Daemen A, Reeder J, Haverty PM, Forrest WF, Brauer M, Mellman I, Albert ML. PMID: 30463956; PMCID: PMC6294879.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    41. Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1). Proc Natl Acad Sci U S A. 2018 10 23; 115(43):E10119-E10126. Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, Boyd Z, Miley N, Flynn S, Leveque V, Shames DS, Ballinger M, Mocci S, Shankar G, Funke R, Hampton G, Sandler A, Amler L, Mellman I, Chen DS, Hegde PS. PMID: 30297397; PMCID: PMC6205493.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCellsCTClinical Trials
    42. The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function. Cell Rep. 2018 10 02; 25(1):80-94. Hernandez S, Qing J, Thibodeau RH, Du X, Park S, Lee HM, Xu M, Oh S, Navarro A, Roose-Girma M, Newman RJ, Warming S, Nannini M, Sampath D, Kim JM, Grogan JL, Mellman I. PMID: 30282040.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    43. TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. 2018 02 22; 554(7693):544-548. Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Senbabaoglu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T. PMID: 29443960; PMCID: PMC6028240.
      View in: PubMed   Mentions: 2225     Fields:    Translation:HumansAnimalsCells
    44. SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer. J Cell Biol. 2018 02 05; 217(2):763-777. Viotti M, Wilson C, McCleland M, Koeppen H, Haley B, Jhunjhunwala S, Klijn C, Modrusan Z, Arnott D, Classon M, Stephan JP, Mellman I. PMID: 29229751; PMCID: PMC5800801.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    45. Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy. PLoS One. 2017; 12(6):e0177920. Baharom F, Thomas OS, Lepzien R, Mellman I, Chalouni C, Smed-Sörensen A. PMID: 28591131; PMCID: PMC5462357.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    46. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017 03 31; 355(6332):1428-1433. Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. PMID: 28280247; PMCID: PMC6286077.
      View in: PubMed   Mentions: 708     Fields:    Translation:HumansAnimalsCells
    47. Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice. Nat Commun. 2017 02 21; 8:14572. Lau J, Cheung J, Navarro A, Lianoglou S, Haley B, Totpal K, Sanders L, Koeppen H, Caplazi P, McBride J, Chiu H, Hong R, Grogan J, Javinal V, Yauch R, Irving B, Belvin M, Mellman I, Kim JM, Schmidt M. PMID: 28220772; PMCID: PMC5321797.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    48. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017 03 06; 216(3):779-792. Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I. PMID: 28130292; PMCID: PMC5350508.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    49. Elements of cancer immunity and the cancer-immune set point. Nature. 2017 01 18; 541(7637):321-330. Chen DS, Mellman I. PMID: 28102259.
      View in: PubMed   Mentions: 2124     Fields:    Translation:HumansAnimalsCells
    50. Natural killer cell granules converge to avoid collateral damage. J Cell Biol. 2016 Dec 19; 215(6):765-767. Ritter AT, Mellman I. PMID: 27932575; PMCID: PMC5166509.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    51. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016 09 07; 7:12742. Chung I, Reichelt M, Shao L, Akita RW, Koeppen H, Rangell L, Schaefer G, Mellman I, Sliwkowski MX. PMID: 27599456; PMCID: PMC5023959.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    52. Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule. J Immunother Cancer. 2016; 4:37. Kaufman HL, Butterfield LH, Coulie PG, Demaria S, Ferris RL, Galon J, Khleif SN, Mellman I, Ohashi PS, Overwijk WW, Topalian SL, Marincola FM. PMID: 27330810; PMCID: PMC4915147.
      View in: PubMed   Mentions:    Fields:    
    53. Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop. Oncoimmunology. 2016 Jul; 5(7):e1186323. Houot R, Gaulard P, Schreiber R, Mellman I, Lambotte O, Coulie PG, Fest T, Korman A, Levy R, Shipp M, Tarte K, Kohrt H, Marabelle A, Ansell S, Watier H, van Elsas A, Balakumaran A, Arce Vargas F, Quezada SA, Salles G, Olive D. PMID: 27622041; PMCID: PMC5006908.
      View in: PubMed   Mentions: 2     Fields:    
    54. The Human Vaccines Project: A roadmap for cancer vaccine development. Sci Transl Med. 2016 Apr 13; 8(334):334ps9. Romero P, Banchereau J, Bhardwaj N, Cockett M, Disis ML, Dranoff G, Gilboa E, Hammond SA, Hershberg R, Korman AJ, Kvistborg P, Melief C, Mellman I, Palucka AK, Redchenko I, Robins H, Sallusto F, Schenkelberg T, Schoenberger S, Sosman J, Türeci Ö, Van den Eynde B, Koff W, Coukos G. PMID: 27075624.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    55. De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Cancer Immunol Res. 2016 Apr; 4(4):279-88. Mellman I, Hubbard-Lucey VM, Tontonoz MJ, Kalos MD, Chen DS, Allison JP, Drake CG, Levitsky H, Lonberg N, van der Burg SH, Fearon DT, Wherry EJ, Lowy I, Vonderheide RH, Hwu P. PMID: 27036972.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    56. MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade. Immunity. 2016 Mar 15; 44(3):609-621. Ebert PJR, Cheung J, Yang Y, McNamara E, Hong R, Moskalenko M, Gould SE, Maecker H, Irving BA, Kim JM, Belvin M, Mellman I. PMID: 26944201.
      View in: PubMed   Mentions: 337     Fields:    Translation:HumansAnimalsCells
    57. Voices of biotech. Nat Biotechnol. 2016 Mar; 34(3):270-5. Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, Khvorova A, Kim DH, Kim JS, Krishnan Y, Lakadamyali M, Lappalainen T, Lewin S, Liao J, Loman N, Lundberg E, Lynd L, Martin C, Mellman I, Miyawaki A, Mummery C, Nelson K, Paz J, Peralta-Yahya P, Picotti P, Polyak K, Prather K, Qin J, Quake S, Regev A, Rogers JA, Shetty R, Sommer M, Stevens M, Stolovitzky G, Takahashi M, Tang F, Teichmann S, Torres-Padilla ME, Tripathi L, Vemula P, Verdine G, Vollmer F, Wang J, Ying JY, Zhang F, Zhang T. PMID: 26963549.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    58. Is all cancer therapy immunotherapy? Sci Transl Med. 2015 Nov 25; 7(315):315fs48. Belvin M, Mellman I. PMID: 26606965.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    59. Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14664-9. Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. PMID: 26561586; PMCID: PMC4664370.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    60. Cancer immunotherapy. Neo approaches to cancer vaccines. Science. 2015 May 15; 348(6236):760-1. Delamarre L, Mellman I, Yadav M. PMID: 25977539.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    61. Immunotherapy: The path to win the war on cancer? Cell. 2015 Apr 09; 161(2):185-6. Topalian SL, Wolchok JD, Chan TA, Mellman I, Palucka K, Banchereau J, Rosenberg SA, Dane Wittrup K. PMID: 26042237; PMCID: PMC6369529.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    62. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol. 2015 May 01; 194(9):4422-30. Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren KJ, McInerney GM, Karlsson Hedestam GB, Mellman I, Smed-Sörensen A. PMID: 25801434.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    63. β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2823-8. Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. PMID: 25730849; PMCID: PMC4352820.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    64. Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Mol Biol Cell. 2015 Apr 01; 26(7):1273-85. Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM. PMID: 25631815; PMCID: PMC4454175.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    65. Single-molecule optical methods analyzing receptor tyrosine kinase activation in living cells. Methods Mol Biol. 2015; 1233:35-44. Chung I, Mellman I. PMID: 25319887.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    66. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014 Nov 27; 515(7528):563-7. Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS. PMID: 25428504; PMCID: PMC4836193.
      View in: PubMed   Mentions: 2492     Fields:    Translation:HumansCellsCTClinical Trials
    67. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 2014 Nov 27; 515(7528):572-6. Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L. PMID: 25428506.
      View in: PubMed   Mentions: 565     Fields:    Translation:AnimalsCells
    68. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 2014 May 08; 509(7499):240-4. Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. PMID: 24695226.
      View in: PubMed   Mentions: 147     Fields:    Translation:AnimalsCells
    69. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol. 2014 Feb; 15(2):161-7. Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. PMID: 24362890.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    70. Endocytosis and cancer. Cold Spring Harb Perspect Biol. 2013 Dec 01; 5(12):a016949. Mellman I, Yarden Y. PMID: 24296170; PMCID: PMC3839607.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansCells
    71. A Nobel Prize for membrane traffic: vesicles find their journey's end. J Cell Biol. 2013 Nov 25; 203(4):559-61. Mellman I, Emr SD. PMID: 24215073; PMCID: PMC3840937.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    72. Antibody therapeutics in cancer. Science. 2013 Sep 13; 341(6151):1192-8. Sliwkowski MX, Mellman I. PMID: 24031011.
      View in: PubMed   Mentions: 223     Fields:    Translation:Humans
    73. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells. J Leukoc Biol. 2014 Jan; 95(1):179-90. Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. PMID: 24023259.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    74. Dendritic cells: master regulators of the immune response. Cancer Immunol Res. 2013 Sep; 1(3):145-9. Mellman I. PMID: 24777676.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    75. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013 Jul 25; 39(1):1-10. Chen DS, Mellman I. PMID: 23890059.
      View in: PubMed   Mentions: 2633     Fields:    Translation:HumansCells
    76. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med. 2013 Jun 03; 210(6):1069-77. Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. PMID: 23712430; PMCID: PMC3674695.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    77. Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation. J Exp Med. 2013 May 06; 210(5):1049-63. Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. PMID: 23569326; PMCID: PMC3646496.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    78. Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways. J Cell Biol. 2012 Dec 24; 199(7):1117-30. Lo B, Strasser G, Sagolla M, Austin CD, Junttila M, Mellman I. PMID: 23266956; PMCID: PMC3529533.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    79. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 2012 Sep 06; 120(10):2011-20. Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. PMID: 22791285.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    80. Profile of Ira Mellman. Interview by Prashant Nair. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8790-2. Mellman I. PMID: 22645337; PMCID: PMC3384157.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    81. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8820-7. Ma JK, Platt MY, Eastham-Anderson J, Shin JS, Mellman I. PMID: 22566640; PMCID: PMC3384207.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    82. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Apr 03; 109(14):5299-304. Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. PMID: 22431598; PMCID: PMC3325706.
      View in: PubMed   Mentions: 267     Fields:    Translation:HumansCells
    83. Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. PLoS Pathog. 2012; 8(3):e1002572. Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. PMID: 22412374; PMCID: PMC3297599.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    84. Cancer immunotherapy comes of age. Nature. 2011 Dec 21; 480(7378):480-9. Mellman I, Coukos G, Dranoff G. PMID: 22193102; PMCID: PMC3967235.
      View in: PubMed   Mentions: 1515     Fields:    Translation:HumansCells
    85. Remembering Ralph Steinman. J Exp Med. 2011 Nov 21; 208(12):2343-7. Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. PMID: 22216461; PMCID: PMC3256974.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    86. Retrospective. Ralph M. Steinman (1943-2011). Science. 2011 Oct 28; 334(6055):466. Mellman I, Nussenzweig M. PMID: 22034425.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    87. Ralph Steinman (1943-2011). Nature. 2011 Oct 26; 478(7370):460. Nussenzweig MC, Mellman I. PMID: 22031432.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    88. A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol. 2011 Apr 04; 193(1):219-33. Francis SS, Sfakianos J, Lo B, Mellman I. PMID: 21444686; PMCID: PMC3082196.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    89. AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. J Biol Chem. 2011 May 13; 286(19):16879-90. Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. PMID: 21383016; PMCID: PMC3089531.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    90. Harnessing dendritic cells for immunotherapy. Semin Immunol. 2011 Feb; 23(1):2-11. Delamarre L, Mellman I. PMID: 21377379.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    91. Cell biology redux. Mol Biol Cell. 2010 Nov 15; 21(22):3809-10. Mellman I. PMID: 21079023; PMCID: PMC2982128.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    92. Designing vaccines based on biology of human dendritic cell subsets. Immunity. 2010 Oct 29; 33(4):464-78. Palucka K, Banchereau J, Mellman I. PMID: 21029958; PMCID: PMC2975953.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    93. Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly. Biochem Biophys Res Commun. 2010 Sep 17; 400(2):271-7. Togawa A, Sfakianos J, Ishibe S, Suzuki S, Fujigaki Y, Kitagawa M, Mellman I, Cantley LG. PMID: 20728428; PMCID: PMC3182281.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    94. Immunology. Beta-catenin balances immunity. Science. 2010 Aug 13; 329(5993):767-9. Mellman I, Clausen BE. PMID: 20705838.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    95. Monocyte-derived dendritic cells exhibit increased levels of lysosomal proteolysis as compared to other human dendritic cell populations. PLoS One. 2010 Aug 02; 5(8):e11949. McCurley N, Mellman I. PMID: 20689855; PMCID: PMC2914042.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    96. Trafficking guidance receptors. Cold Spring Harb Perspect Biol. 2010 Jul; 2(7):a001826. Winckler B, Mellman I. PMID: 20504966; PMCID: PMC2890194.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    97. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 2010 Apr 01; 464(7289):783-7. Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. PMID: 20208517.
      View in: PubMed   Mentions: 257     Fields:    Translation:HumansAnimalsCells
    98. Antigen processing and presentation. Curr Opin Immunol. 2010 Feb; 22(1):78-80. Mellman I, Cresswell P. PMID: 20172702.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    99. Mature dendritic cells use endocytic receptors to capture and present antigens. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4287-92. Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. PMID: 20142498; PMCID: PMC2840134.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    100. Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19; 18(1):39-51. Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML. PMID: 20152176; PMCID: PMC3178410.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    101. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res. 2009 Sep 01; 15(17):5323-37. Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, Mellman I, Prindiville SA, Viner JL, Weiner LM, Matrisian LM. PMID: 19723653; PMCID: PMC5779623.
      View in: PubMed   Mentions: 651     Fields:    Translation:Humans
    102. Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. J Cell Biol. 2009 Jul 27; 186(2):269-82. Farr GA, Hull M, Mellman I, Caplan MJ. PMID: 19620635; PMCID: PMC2717640.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    103. Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 2009 May 18; 27(23):3013-21. Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. PMID: 19428913; PMCID: PMC2695996.
      View in: PubMed   Mentions: 123     Fields:    Translation:AnimalsCellsPHPublic Health
    104. Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 2009; 214(7):495-505. Becker SM, Delamarre L, Mellman I, Andrews NW. PMID: 19157638; PMCID: PMC4737586.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    105. Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol. 2009 Jan 26; 184(2):281-96. Mao YS, Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli P, Lu CY, Yin HL. PMID: 19153220; PMCID: PMC2654300.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    106. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med. 2009 Feb 16; 206(2):399-410. Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. PMID: 19153244; PMCID: PMC2646567.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    107. By the scientists, for the scientists. J Cell Biol. 2009 Jan 12; 184(1):7-9. Mellman I. PMID: 19139258; PMCID: PMC2615096.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    108. Coordinated protein sorting, targeting and distribution in polarized cells. Nat Rev Mol Cell Biol. 2008 Nov; 9(11):833-45. Mellman I, Nelson WJ. PMID: 18946473; PMCID: PMC3369829.
      View in: PubMed   Mentions: 271     Fields:    Translation:HumansAnimalsCells
    109. A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic. 2008 Nov; 9(11):1915-24. Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. PMID: 18764819; PMCID: PMC2820280.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    110. A33 antigen displays persistent surface expression. Cancer Immunol Immunother. 2008 Jul; 57(7):1017-27. Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD. PMID: 18236042; PMCID: PMC2836164.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    111. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond). 2008 Jun; 3(3):343-55. Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. PMID: 18510429; PMCID: PMC5545123.
      View in: PubMed   Mentions: 23     Fields:    
    112. Spinophilin participates in information transfer at immunological synapses. J Cell Biol. 2008 Apr 21; 181(2):203-11. Bloom O, Unternaehrer JJ, Jiang A, Shin JS, Delamarre L, Allen P, Mellman I. PMID: 18411312; PMCID: PMC2315669.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    113. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008 May; 9(5):551-7. Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE. PMID: 18376401; PMCID: PMC2695657.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansCells
    114. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol. 2008 May; 10(5):1190-207. Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. PMID: 18194483; PMCID: PMC2861895.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    115. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007 Dec 17; 179(6):1133-40. Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, Toomre D, Mellman I. PMID: 18070914; PMCID: PMC2140027.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    116. Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia. 2007 Dec; 9(12):1099-110. Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. PMID: 18084617; PMCID: PMC2134906.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    117. Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity. 2007 Oct; 27(4):610-24. Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, Jiang S, Whitney JA, Connolly J, Banchereau J, Mellman I. PMID: 17936032; PMCID: PMC2151979.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    118. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007 Oct 04; 449(7162):564-9. Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, Cao W, Wang YH, Su B, Nestle FO, Zal T, Mellman I, Schröder JM, Liu YJ, Gilliet M. PMID: 17873860.
      View in: PubMed   Mentions: 740     Fields:    Translation:HumansCells
    119. Private lives: reflections and challenges in understanding the cell biology of the immune system. Science. 2007 Aug 03; 317(5838):625-7. Mellman I. PMID: 17673653.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    120. How the rich get richer. J Exp Med. 2007 Jul 09; 204(7):1503. Rossner M, Mellman I. PMID: 17576780; PMCID: PMC2118635.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    121. How the rich get richer. J Cell Biol. 2007 Jun 18; 177(6):951. Rossner M, Mellman I. PMID: 17562793; PMCID: PMC2064355.
      View in: PubMed   Mentions: 2     Fields:    
    122. Ira Mellman: from endosomes to industry. Interview by William A Wells. J Cell Biol. 2007 May 21; 177(4):570-1. Mellman I. PMID: 17517958; PMCID: PMC2064202.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    123. Incomplete screening? Nat Immunol. 2007 May; 8(5):473. Mellman I. PMID: 17440454.
      View in: PubMed   Mentions:    Fields:    
    124. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):234-9. Unternaehrer JJ, Chow A, Pypaert M, Inaba K, Mellman I. PMID: 17190803; PMCID: PMC1765441.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    125. Bringing science to cancer therapy. Yale J Biol Med. 2006 Dec; 79(3-4):177-8. Mellman I. PMID: 17940629; PMCID: PMC1994804.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    126. Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic. 2007 Jan; 8(1):47-60. Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K. PMID: 17132146.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    127. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 2006 Nov 02; 444(7115):115-8. Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. PMID: 17051151.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    128. Modulation of cell adhesion and motility in the immune system by Myo1f. Science. 2006 Oct 06; 314(5796):136-9. Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. PMID: 17023661.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    129. Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. J Exp Med. 2006 Sep 04; 203(9):2049-55. Delamarre L, Couture R, Mellman I, Trombetta ES. PMID: 16908625; PMCID: PMC2118388.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    130. Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. J Cell Biol. 2006 Mar 27; 172(7):1035-44. Hua W, Sheff D, Toomre D, Mellman I. PMID: 16567501; PMCID: PMC2063761.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    131. CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol. 2006 Mar 27; 172(7):1045-56. Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S. PMID: 16567502; PMCID: PMC2063762.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    132. Presentation of self-antigens on MHC class II molecules during dendritic cell maturation. Int Immunol. 2006 Jan; 18(1):199-209. Zwickey HL, Unternaehrer JJ, Mellman I. PMID: 16361313.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    133. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 2005 Oct 07; 123(1):157-70. Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, Mellman I, Grinstein S. PMID: 16213220.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    134. Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. J Cell Biol. 2005 Aug 15; 170(4):595-605. Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. PMID: 16087710; PMCID: PMC2171499.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    135. Targeting antigen to CD19 on B cells efficiently activates T cells. Int Immunol. 2005 Jul; 17(7):869-77. Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ. PMID: 15967786.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    136. The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. FASEB J. 2005 May; 19(7):780-2. Johns TG, Mellman I, Cartwright GA, Ritter G, Old LJ, Burgess AW, Scott AM. PMID: 15774576.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    137. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science. 2005 Mar 11; 307(5715):1630-4. Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. PMID: 15761154.
      View in: PubMed   Mentions: 328     Fields:    Translation:AnimalsCells
    138. Old lysosomes, new tricks: MHC II dynamics in DCs. Trends Immunol. 2005 Feb; 26(2):72-8. Chow AY, Mellman I. PMID: 15668121.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    139. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol. 2005; 23:975-1028. Trombetta ES, Mellman I. PMID: 15771591.
      View in: PubMed   Mentions: 444     Fields:    Translation:HumansAnimalsCells
    140. Antigen processing and presentation by dendritic cells: cell biological mechanisms. Adv Exp Med Biol. 2005; 560:63-7. Mellman I. PMID: 15932021.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    141. Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. J Immunol. 2004 Nov 15; 173(10):6119-24. Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K. PMID: 15528348.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    142. Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. J Cell Biol. 2004 Nov 08; 167(3):531-43. Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I. PMID: 15534004; PMCID: PMC2172492.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    143. IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14467-72. Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S. PMID: 15383663; PMCID: PMC521945.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    144. The JEM and the JCB: a synergistic partnership. J Cell Biol. 2004 Aug 30; 166(5):611. Steinman RM, Mellman I. PMID: 15337771; PMCID: PMC2172438.
      View in: PubMed   Mentions:    Fields:    
    145. Immunotherapy: bewitched, bothered, and bewildered no more. Science. 2004 Jul 09; 305(5681):197-200. Steinman RM, Mellman I. PMID: 15247468.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    146. Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic. 2004 Jun; 5(6):449-61. Duffield A, Fölsch H, Mellman I, Caplan MJ. PMID: 15117319.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    147. The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. J Cell Biol. 2004 Mar 29; 164(7):1055-64. Chang HC, Hull M, Mellman I. PMID: 15051737; PMCID: PMC2172058.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    148. Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol. 2004 Feb; 6(2):106-12. Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ, Malhotra V. PMID: 14743217; PMCID: PMC3372901.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    149. The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. J Cell Biol. 2003 Oct 27; 163(2):339-50. Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I. PMID: 14581456; PMCID: PMC2173525.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    150. The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. J Cell Biol. 2003 Oct 27; 163(2):351-62. Fölsch H, Pypaert M, Maday S, Pelletier L, Mellman I. PMID: 14581457; PMCID: PMC2173537.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    151. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. J Exp Med. 2003 Jul 07; 198(1):111-22. Delamarre L, Holcombe H, Mellman I. PMID: 12835477; PMCID: PMC2196081.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    152. Computational cell biology. J Cell Biol. 2003 May 12; 161(3):463-4. Mellman I, Misteli T. PMID: 12743098; PMCID: PMC2172937.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    153. Activation of lysosomal function during dendritic cell maturation. Science. 2003 Feb 28; 299(5611):1400-3. Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. PMID: 12610307.
      View in: PubMed   Mentions: 264     Fields:    Translation:AnimalsCells
    154. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 2002 Aug 29; 418(6901):988-94. Chow A, Toomre D, Garrett W, Mellman I. PMID: 12198549.
      View in: PubMed   Mentions: 138     Fields:    Translation:AnimalsCells
    155. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10629-34. Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett W, Old LJ, Mellman I. PMID: 12138174; PMCID: PMC124995.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    156. Regulation and functional insights in cellular polarity, Madrid, Spain June 3-5, 2002. J Cell Biol. 2002 Jul 08; 158(1):12-6. Mellman I, Ridley A. PMID: 12141270; PMCID: PMC2173012.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    157. Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Mol Biol Cell. 2002 Jul; 13(7):2374-82. Sugimoto H, Sugahara M, Fölsch H, Koide Y, Nakatsu F, Tanaka N, Nishimura T, Furukawa M, Mullins C, Nakamura N, Mellman I, Ohno H. PMID: 12134076; PMCID: PMC117320.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    158. Transferrin receptor recycling in the absence of perinuclear recycling endosomes. J Cell Biol. 2002 Mar 04; 156(5):797-804. Sheff D, Pelletier L, O'Connell CB, Warren G, Mellman I. PMID: 11877458; PMCID: PMC2173326.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    159. Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Mol Biol Cell. 2002 Jan; 13(1):262-75. Sheff DR, Kroschewski R, Mellman I. PMID: 11809838; PMCID: PMC65087.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    160. Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor. J Cell Biol. 1985 May; 100(5):1515-21. Horwich AL, Fenton WA, Firgaira FA, Fox JE, Kolansky D, Mellman IS, Rosenberg LE. PMID: 3988798; PMCID: PMC2113848.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    161. Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. J Cell Biol. 1983 Mar; 96(3):887-95. Mellman IS, Plutner H, Steinman RM, Unkeless JC, Cohn ZA. PMID: 6833386; PMCID: PMC2112389.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    162. Endocytosis and the recycling of plasma membrane. J Cell Biol. 1983 Jan; 96(1):1-27. Steinman RM, Mellman IS, Muller WA, Cohn ZA. PMID: 6298247; PMCID: PMC2112240.
      View in: PubMed   Mentions: 396     Fields:    Translation:AnimalsCells
    163. Interferon action: effects of mouse alpha and beta interferons on rosette formation, phagocytosis, and surface-antigen expression of cells of the macrophage-type line RAW 309Cr.1. Cell Immunol. 1982 Oct; 73(1):128-40. Yoshie O, Mellman IS, Broeze RJ, Garcia-Blanco M, Lengyel P. PMID: 6185239.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    164. Endocytosis, membrane recycling and Fc receptor function. Ciba Found Symp. 1982; (92):35-58. Mellman IS. PMID: 6924894.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    165. Structural Aspects and Heterogeneity of Immunoglobulin Fc Receptors. Adv Immunol. 1981; 31:247-70. Unkeless JC, Fleit H, Mellman IS. PMID: 7032255.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    166. Transmembrane transport of cobalamin in prokaryotic and eukaryotic cells. Annu Rev Biochem. 1981; 50:1053-86. Sennett C, Rosenberg LE, Mellman IS. PMID: 6267986.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    167. Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages. J Exp Med. 1980 Nov 01; 152(5):1248-61. Steinman RM, Nogueira N, Witmer MD, Tydings JD, Mellman IS. PMID: 6448907; PMCID: PMC2185993.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    168. Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody. J Exp Med. 1980 Oct 01; 152(4):1048-69. Mellman IS, Unkeless JC. PMID: 6158545; PMCID: PMC2185962.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    169. Selective iodination and polypeptide composition of pinocytic vesicles. J Cell Biol. 1980 Sep; 86(3):712-22. Mellman IS, Steinman RM, Unkeless JC, Cohn ZA. PMID: 7410475; PMCID: PMC2110683.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    170. Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1. Proc Natl Acad Sci U S A. 1979 Jan; 76(1):405-9. Mellman IS, Lin PF, Ruddle FH, Rosenberg LE. PMID: 284356; PMCID: PMC382948.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    171. Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts. Exp Cell Res. 1979 Jan; 118(1):127-34. Youngdahl-Turner P, Mellman IS, Allen RH, Rosenberg LE. PMID: 759210.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    172. The chemical composition of the cell wall of Chlamydomonas gymnogama and the concept of a plant cell wall protein. J Cell Biol. 1974 Nov; 63(2 Pt 1):420-9. Miller DH, Mellman IS, Lamport DT, Miller M. PMID: 4607708; PMCID: PMC2110943.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
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