Iris Karina Gratz, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
Address513 Parnassus Ave
San Francisco CA 94143
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    NIH R03AR064554Aug 1, 2013 - May 31, 2016
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bauer JW, Koller J, Murauer EM, De Rosa L, Enzo E, Carulli S, Bondanza S, Recchia A, Muss W, Diem A, Mayr E, Schlager P, Gratz IK, Pellegrini G, De Luca M. Closure of a large chronic wound through transplantation of gene-corrected epidermal stem cells. J Invest Dermatol. 2016 Nov 10. PMID: 27840234.
      View in: PubMed
    2. Daud AI, Loo K, Pauli ML, Sanchez-Rodriguez R, Sandoval PM, Taravati K, Tsai K, Nosrati A, Nardo L, Alvarado MD, Algazi AP, Pampaloni MH, Lobach IV, Hwang J, Pierce RH, Gratz I, Krummel MF, Rosenblum MD, et al. Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma. J Clin Invest. 2016 Aug 15. PMID: 27525433.
      View in: PubMed
    3. Scharschmidt TC, Vasquez KS, Truong HA, Gearty SV, Pauli ML, Nosbaum A, Gratz IK, Otto M, Moon JJ, Liese J, Abbas AK, Fischbach MA, Rosenblum MD. A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes. Immunity. 2015 Nov 17; 43(5):1011-21. PMID: 26588783; PMCID: PMC4654993 [Available on 11/17/16].
    4. Gratz IK, Campbell DJ. Organ-specific and memory treg cells: specificity, development, function, and maintenance. Front Immunol. 2014; 5:333. PMID: 25076948; PMCID: PMC4098124.
    5. Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, Debbaneh MG, Butler D, Huynh M, Levin EC, Leon A, Hoffman WY, McGrath MH, Alvarado MD, Ludwig CH, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD. Memory regulatory T cells reside in human skin. J Clin Invest. 2014 Mar; 124(3):1027-36. PMID: 24509084; PMCID: PMC3934172.
    6. Gratz IK, Rosenblum MD, Maurano MM, Paw JS, Truong HA, Marshak-Rothstein A, Abbas AK. Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues. J Immunol. 2014 Feb 15; 192(4):1351-5. PMID: 24442443; PMCID: PMC3925257.
    7. Gratz IK, Truong HA, Yang SH, Maurano MM, Lee K, Abbas AK, Rosenblum MD. Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol. 2013 May 1; 190(9):4483-7. PMID: 23543753; PMCID: PMC3660612.
    8. Gratz IK, Rosenblum MD, Abbas AK. The life of regulatory T cells. Ann N Y Acad Sci. 2013 Apr; 1283:8-12. PMID: 23402657.
      View in: PubMed
    9. Ettinger M, Gratz IK, Gruber C, Hauser-Kronberger C, Johnson TS, Mahnke K, Thalhamer J, Hintner H, Peckl-Schmid D, Bauer JW. Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen. Exp Dermatol. 2012 May; 21(5):395-8. PMID: 22509840.
      View in: PubMed
    10. Rosenblum MD, Gratz IK, Paw JS, Abbas AK. Treating human autoimmunity: current practice and future prospects. Sci Transl Med. 2012 Mar 14; 4(125):125sr1. PMID: 22422994; PMCID: PMC4061980.
    11. Ettinger M, Peckl-Schmid D, Gruber C, Laimer M, Thalhamer J, Hintner H, Gratz IK, Bauer JW. Transcutaneous gene gun delivery of hNC16A Induces BPAG2-specific tolerance. J Invest Dermatol. 2012 Jun; 132(6):1665-71. PMID: 22377765.
      View in: PubMed
    12. Rosenblum MD, Gratz IK, Paw JS, Lee K, Marshak-Rothstein A, Abbas AK. Response to self antigen imprints regulatory memory in tissues. Nature. 2011 Dec 22; 480(7378):538-42. PMID: 22121024; PMCID: PMC3263357.
    13. Katzman SD, Hoyer KK, Dooms H, Gratz IK, Rosenblum MD, Paw JS, Isakson SH, Abbas AK. Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine. 2011 Oct; 56(1):116-21. PMID: 21807532; PMCID: PMC3171642.
    14. Gruber C, Gratz IK, Murauer EM, Mayr E, Koller U, Bruckner-Tuderman L, Meneguzzi G, Hintner H, Bauer JW. Spliceosome-mediated RNA trans-splicing facilitates targeted delivery of suicide genes to cancer cells. Mol Cancer Ther. 2011 Feb; 10(2):233-41. PMID: 21209069.
      View in: PubMed
    15. Peckl-Schmid D, Wolkerstorfer S, Königsberger S, Achatz-Straussberger G, Feichtner S, Schwaiger E, Zaborsky N, Huemer M, Gratz IK, Schibli R, Lamers M, Crameri R, Moser K, Luger EO, Achatz G. HAX1 deficiency: impact on lymphopoiesis and B-cell development. Eur J Immunol. 2010 Nov; 40(11):3161-72. PMID: 20865787.
      View in: PubMed
    16. Murauer EM, Gache Y, Gratz IK, Klausegger A, Muss W, Gruber C, Meneguzzi G, Hintner H, Bauer JW. Functional correction of type VII collagen expression in dystrophic epidermolysis bullosa. J Invest Dermatol. 2011 Jan; 131(1):74-83. PMID: 20720561.
      View in: PubMed
    17. Oberndorfer I, Schmid D, Geisberger R, Achatz-Straussberger G, Crameri R, Lamers M, Achatz G. HS1-associated protein X-1 interacts with membrane-bound IgE: impact on receptor-mediated internalization. J Immunol. 2006 Jul 15; 177(2):1139-45. PMID: 16818771.
      View in: PubMed
    18. Achatz-Straussberger G, Geisberger R, Oberndorfer I, Inführ D, Luger E, Fallon P, Lamers M, Achatz G. Construction of an sIgE:FLAG-mIgE:GFP reporter mouse strain. Int Arch Allergy Immunol. 2003 Apr; 130(4):280-7. PMID: 12740529.
      View in: PubMed
    19. Geisberger R, Prlic M, Achatz-Straussberger G, Oberndorfer I, Luger E, Lamers M, Crameri R, Appenzeller U, Wienands J, Breitenbach M, Ferreira F, Achatz G. Phage display based cloning of proteins interacting with the cytoplasmic tail of membrane immunoglobulins. Dev Immunol. 2002 Sep; 9(3):127-34. PMID: 12885153; PMCID: PMC2276102.
    20. Mengesdorf T, Althausen S, Oberndorfer I, Paschen W. Response of neurons to an irreversible inhibition of endoplasmic reticulum Ca(2+)-ATPase: relationship between global protein synthesis and expression and translation of individual genes. Biochem J. 2001 Jun 15; 356(Pt 3):805-12. PMID: 11389688; PMCID: PMC1221907.
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