James Huang • UCSF Profiles

James Huang, MD

Title(s)	Professor, Pediatrics
School	School of Medicine
Address	550 16th Street, #001 San Francisco CA 94158
Phone	415-476-3831
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Biography

Education and Training

Harvard College, Cambridge, MA	AB	06/1986	Biochemical Sciences
Baylor College of Medicine, Houston, TX	MD	05/1991	Medicine
Johns Hopkins Hospital, Baltimore, MD		06/1994	Pediatrics Residency
Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA		06/1997	Pediatric Hematology/Oncology Fellowship

Overview

Interests

hemostasis and thrombosis, bone marrow failure, immune cytopenia

Websites

Clinical Profile at UCSF Benioff Children's Hospital

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients. Pediatr Blood Cancer. 2022 05; 69(5):e29641. Higham CS, Shimano KA, Melton A, Kharbanda S, Chu J, Dara J, Winestone LE, Hermiston ML, Huang JN, Dvorak CC. PMID: 35253361.

View in: PubMed Mentions: 7 Fields:
Hem Hematology Neo Neoplasms Ped Pediatrics
Translation:Humans CTClinical Trials
Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 11 01; 96(11):1491-1504. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. PMID: 34342889.

View in: PubMed Mentions: 6 Fields:
Hem Hematology
Translation:Humans
Plasma-derived factor X concentrate compassionate use for hereditary factor X deficiency: Long-term safety and efficacy in a retrospective data-collection study. Res Pract Thromb Haemost. 2021 Jul; 5(5):e12550. Huang JN, Liesner R, Austin SK, Kavakli K, Akanezi C. PMID: 34263102; PMCID: PMC8268662.

View in: PubMed Mentions: 2
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Nat Commun. 2021 02 26; 12(1):1334. Kennedy AL, Myers KC, Bowman J, Gibson CJ, Camarda ND, Furutani E, Muscato GM, Klein RH, Ballotti K, Liu S, Harris CE, Galvin A, Malsch M, Dale D, Gansner JM, Nakano TA, Bertuch A, Vlachos A, Lipton JM, Castillo P, Connelly J, Churpek J, Edwards JR, Hijiya N, Ho RH, Hofmann I, Huang JN, Keel S, Lamble A, Lau BW, Norkin M, Stieglitz E, Stock W, Walkovich K, Boettcher S, Brendel C, Fleming MD, Davies SM, Weller EA, Bahl C, Carter SL, Shimamura A, Lindsley RC. PMID: 33637765; PMCID: PMC7910481.

View in: PubMed Mentions: 61 Fields:
Bio Biology Sci Science
Translation:Humans Cells
A study assessing the feasibility of randomization of pediatric and young adult patients between matched unrelated donor bone marrow transplantation and immune-suppressive therapy for newly diagnosed severe aplastic anemia: A joint pilot trial of the North American Pediatric Aplastic Anemia Consortium and the Pediatric Transplantation and Cellular Therapy Consortium. Pediatr Blood Cancer. 2020 10; 67(10):e28444. Pulsipher MA, Lehmann LE, Bertuch AA, Sasa G, Olson T, Nakano T, Gilio A, Burroughs LM, Lipton JM, Huang JN, Dickerson K, Bertaina A, Zhuang C, Malsch M, Fleming M, Weller E, Shimamura A, Williams DA. PMID: 32776425; PMCID: PMC9533334.

View in: PubMed Mentions: 3 Fields:
Hem Hematology Neo Neoplasms Ped Pediatrics
Translation:Humans
Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study. Haematologica. 2019 10; 104(10):1974-1983. Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. PMID: 30948484; PMCID: PMC6886407.

View in: PubMed Mentions: 16 Fields:
Hem Hematology
Translation:Humans CTClinical Trials
Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency. Biol Blood Marrow Transplant. 2019 07; 25(7):1355-1362. Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ. PMID: 30876930; PMCID: PMC7384257.

View in: PubMed Mentions: 12 Fields:
Hem Hematology Tra Transplantation
Translation:Humans Cells CTClinical Trials
Investigation of Pediatric Anemia in the Commonwealth of the Northern Mariana Islands. Matern Child Health J. 2019 Mar; 23(3):416-421. Lin TF, Huang JN, Cash HL. PMID: 30661189.

View in: PubMed Mentions: Fields:
Per Perinatology
Translation:Humans
Understanding the evolving phenotype of vascular complications in telomere biology disorders. Angiogenesis. 2019 02; 22(1):95-102. Higgs C, Crow YJ, Adams DM, Chang E, Hayes D, Herbig U, Huang JN, Himes R, Jajoo K, Johnson FB, Reynolds SD, Yonekawa Y, Armanios M, Boulad F, DiNardo CD, Dufour C, Goldman FD, Khan S, Kratz C, Myers KC, Raghu G, Alter BP, Aubert G, Bhala S, Cowen EW, Dror Y, El-Youssef M, Friedman B, Giri N, Helms Guba L, Khincha PP, Lin TF, Longhurst H, McReynolds LJ, Nelson A, Olson T, Pariser A, Perona R, Sasa G, Schratz K, Simonetto DA, Townsley D, Walsh M, Stevens K, Agarwal S, Bertuch AA, Savage SA, Clinical Care Consortium for Telomere-associated Ailments (CCCTAA). PMID: 30168024.

View in: PubMed Mentions: 16 Fields:
Hem Hematology
Translation:Humans Animals Cells
Comprehensive Review of Preschool Age Anemia in the Pacific Island Jurisdictions. Hawaii J Med Public Health. 2017 12; 76(12):331-336. Lin TF, Huang JN, Cash HL. PMID: 29242758; PMCID: PMC5725618.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)Pub Public Health
Translation:Humans
Capacity Building for Rare Bleeding Disorders in the Remote Commonwealth of the Northern Mariana Islands. Am J Public Health. 2016 Apr; 106(4):658-61. Lin TF, Carhill P, Huang JN, Baker JR. PMID: 26890163; PMCID: PMC4816151.

View in: PubMed Mentions: 1 Fields:
Pub Public Health
Translation:Humans
Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Ann Hematol. 2014 Jul; 93(7):1139-48. Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP. PMID: 24577514; PMCID: PMC4467727.

View in: PubMed Mentions: 6 Fields:
Hem Hematology
Translation:Humans
Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer. 2014 May; 61(5):869-74. Williams DA, Bennett C, Bertuch A, Bessler M, Coates T, Corey S, Dror Y, Huang J, Lipton J, Olson TS, Reiss UM, Rogers ZR, Sieff C, Vlachos A, Walkovich K, Wang W, Shimamura A. PMID: 24285674; PMCID: PMC4280184.

View in: PubMed Mentions: 11 Fields:
Hem Hematology Neo Neoplasms Ped Pediatrics
Translation:Humans
Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2013 Oct; 98(4):960-71. Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP. PMID: 23945720; PMCID: PMC3778866.

View in: PubMed Mentions: 14 Fields:
Nut Nutritional Sciences
Translation:Humans
Re: 24-year-old man with previously diagnosed hemophilia. Clin Chem. 2012 Jul; 58(7):1090. Huang JN. PMID: 22745259.

View in: PubMed Mentions: Fields:
Che Chemistry
Translation:Humans
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. J Clin Invest. 2012 Jan; 122(1):408-18. Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA. PMID: 22156199; PMCID: PMC3248292.

View in: PubMed Mentions: 142 Fields:
Med Medicine (General)
Translation:Humans Cells
Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. PLoS One. 2011; 6(10):e26437. Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA. PMID: 22028878; PMCID: PMC3197646.

View in: PubMed Mentions: 21 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Functions of the mitotic B-type cyclins CLB1, CLB2, and CLB3 at mitotic exit antagonized by the CDC14 phosphatase. Fungal Genet Biol. 2011 Oct; 48(10):966-78. Tzeng YW, Huang JN, Schuyler SC, Wu CH, Juang YL. PMID: 21784165.

View in: PubMed Mentions: 2 Fields:
Gen Genetics Mic Microbiology
Translation:Animals
Pseudotumor of the mandible as first presentation of hemophilia in a 2-year-old male: a case report and review of jaw pseudotumors of hemophilia. Head Neck Pathol. 2011 Sep; 5(3):226-32. Cox DP, Solar A, Huang J, Chigurupati R. PMID: 21567186; PMCID: PMC3173544.

View in: PubMed Mentions: 7 Fields:
Neo Neoplasms Pat Pathology
Translation:Humans
Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover. Bone. 2011 Jun 01; 48(6):1305-12. Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS. PMID: 21443975; PMCID: PMC3095710.

View in: PubMed Mentions: 19 Fields:
Met Metabolism Ort Orthopedics
Translation:Humans
Clinical spectrum and molecular pathophysiology of Shwachman-Diamond syndrome. Curr Opin Hematol. 2011 Jan; 18(1):30-5. Huang JN, Shimamura A. PMID: 21124213; PMCID: PMC3485416.

View in: PubMed Mentions: 19 Fields:
Hem Hematology
Translation:Humans
Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010 Sep; 41(9):2108-29. Morgenstern LB, Hemphill JC, Anderson C, Becker K, Broderick JP, Connolly ES, Greenberg SM, Huang JN, MacDonald RL, Messé SR, Mitchell PH, Selim M, Tamargo RJ, American Heart Association Stroke Council and Council on Cardiovascular Nursing. PMID: 20651276; PMCID: PMC4462131.

View in: PubMed Mentions: 454 Fields:
Bra Brain Vas Vascular Diseases
Translation:Humans
Factor V deficiency: a concise review. Haemophilia. 2008 Nov; 14(6):1164-9. Huang JN, Koerper MA. PMID: 19141156.

View in: PubMed Mentions: 31 Fields:
Hem Hematology
Translation:Humans
Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J Cell Biol. 2001 Jul 09; 154(1):85-94. Huang JN, Park I, Ellingson E, Littlepage LE, Pellman D. PMID: 11448992; PMCID: PMC2196868.

View in: PubMed Mentions: 56 Fields:
Cel Cell Biology
Translation:Animals Cells
Low-molecular-weight heparins. Hematol Oncol Clin North Am. 1998 Dec; 12(6):1251-81, vi-vii. Huang JN, Shimamura A. PMID: 9922935.

View in: PubMed Mentions: Fields:
Hem Hematology Neo Neoplasms
Translation:Humans
Selection and analysis of rare second-site suppressors of Drosophila RNA polymerase II mutations. Mol Gen Genet. 1998 Jun; 258(5):457-65. Krasnoselskaya I, Huang J, Jones T, Dezan C, Mortin MA. PMID: 9669327.

View in: PubMed Mentions: 3 Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science. 1997 Feb 28; 275(5304):1311-4. Juang YL, Huang J, Peters JM, McLaughlin ME, Tai CY, Pellman D. PMID: 9036857.

View in: PubMed Mentions: 122 Fields:
Sci Science
Translation:Animals Cells
Surface hydrophobicity and water transport of the toad urinary bladder: effects of vasopressin. J Membr Biol. 1988 Dec; 106(2):119-22. Dial EJ, Huang J, O'Neil RG, Hills BA, Lichtenberger LM. PMID: 3147334.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Translation:Animals
Antagonistic interactions between alleles of the RpII215 locus in Drosophila melanogaster. Genetics. 1988 Aug; 119(4):863-73. Mortin MA, Kim WJ, Huang J. PMID: 3137121; PMCID: PMC1203470.

View in: PubMed Mentions: 11 Fields:
Gen Genetics
Translation:Animals Cells
Monoamine oxidase: an important intracellular regulator of gastrin release in the rat. Gastroenterology. 1986 Apr; 90(4):1018-23. Dial EJ, Huang J, Delansorne R, Lichtenberger LM. PMID: 3081396.

View in: PubMed Mentions: 3 Fields:
Gas Gastroenterology
Translation:Animals