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    Jan Stoehr, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentInstitute for Neurodegenerative Diseases
    Address675 Nelson Rising Lane
    San Francisco CA 94158
    Phone415-502-7092
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoPostdoctoral StudiesGraduate Division
      Collapse Awards and Honors
      Alzheimer's Association2015 - 2017New Investigator Research Grant
      Glenn Foundation2013 - 2015Glenn Award for Research in Biological Mechanisms of Aging
      Alzheimer's Association2012 Award for Excellence in Alzheimer’s Research
      John Douglas French Alzheimer's Foundation (JDFAF)2011Art Linketter Award
      John Douglas French Alzheimer's Foundation (JDFAF)2010 - 2012Postdoctoral fellowship
      German Research Foundation (DFG)2008 - 2010Postdoctoral fellowship

      Collapse ORNG Applications 
      Collapse Websites
      Collapse In The News

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M. Structural Polymorphism of Alzheimer's ß-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. J Am Chem Soc. 2016 Aug 10; 138(31):9840-52. PMID: 27414264.
        View in: PubMed
      2. Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophys J. 2015 Aug 18; 109(4):793-805. PMID: 26287631; PMCID: PMC4547163 [Available on 08/18/16].
      3. Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 1; 112(35):E4949-58. PMID: 26286986; PMCID: PMC4568231 [Available on 03/01/16].
      4. Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G. Structural studies of truncated forms of the prion protein PrP. Biophys J. 2015 Mar 24; 108(6):1548-54. PMID: 25809267; PMCID: PMC4375555 [Available on 03/24/16].
      5. Levine DJ, Stöhr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR. Mechanism of scrapie prion precipitation with phosphotungstate anions. ACS Chem Biol. 2015 May 15; 10(5):1269-77. PMID: 25695325; PMCID: PMC4437617.
      6. Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. Distinct synthetic Aß prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10329-34. PMID: 24982137; PMCID: PMC4104853.
      7. Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Serial propagation of distinct strains of Aß prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10323-8. PMID: 24982139; PMCID: PMC4104857.
      8. Rufo CM, Moroz YS, Moroz OV, Stöhr J, Smith TA, Hu X, DeGrado WF, Korendovych IV. Short peptides self-assemble to produce catalytic amyloids. Nat Chem. 2014 Apr; 6(4):303-9. PMID: 24651196; PMCID: PMC3996680.
      9. Luers L, Bannach O, Stöhr J, Wördehoff MM, Wolff M, Nagel-Steger L, Riesner D, Willbold D, Birkmann E. Seeded fibrillation as molecular basis of the species barrier in human prion diseases. PLoS One. 2013; 8(8):e72623. PMID: 23977331; PMCID: PMC3748051.
      10. G. Panza, L. Luers, J. Stöhr, L. Nagel-Steger, J. Weiss, D. Riesner, D. Willbold and E. Birkmann. . Prion Biology: Research and Advances. Prions as Seeds and Recombinant Prion Proteins as Substrates. 2013.
      11. Faculty of 1000 recommendation for: Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, Dearmond SJ, Prusiner SB, Giles K. Purified and synthetic Alzheimer's amyloid beta (Aß) prions. Proc Natl Acad Sci U S A. 2012 Jun 18. . Review. 2012.
      12. Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. Purified and synthetic Alzheimer's amyloid beta (Aß) prions. Proc Natl Acad Sci U S A. 2012 Jul 3; 109(27):11025-30. PMID: 22711819; PMCID: PMC3390876.
      13. Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G. Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold. Biophys J. 2012 May 16; 102(10):2339-44. PMID: 22677387; PMCID: PMC3353098.
      14. Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503. PMID: 22331873; PMCID: PMC3295307.
      15. Stöhr J. Prion protein aggregation and fibrillogenesis in vitro. Subcell Biochem. 2012; 65:91-108. PMID: 23225001.
        View in: PubMed
      16. Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21223-8. PMID: 22160704; PMCID: PMC3248514.
      17. Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. Protease-resistant prions selectively decrease Shadoo protein. PLoS Pathog. 2011 Nov; 7(11):e1002382. PMID: 22163178; PMCID: PMC3219722.
      18. Stöhr J, Elfrink K, Weinmann N, Wille H, Willbold D, Birkmann E, Riesner D. In vitro conversion and seeded fibrillization of posttranslationally modified prion protein. Biol Chem. 2011 May; 392(5):415-21. PMID: 21476870.
        View in: PubMed
      19. Panza G, Luers L, Stöhr J, Nagel-Steger L, Weiss J, Riesner D, Willbold D, Birkmann E. Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro. PLoS One. 2010; 5(12):e14283. PMID: 21151607; PMCID: PMC3000319.
      20. Elfrink K, Ollesch J, Stöhr J, Willbold D, Riesner D, Gerwert K. Structural changes of membrane-anchored native PrP(C). Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31):10815-9. PMID: 18669653; PMCID: PMC2504809.
      21. Panza G, Stöhr J, Dumpitak C, Papathanassiou D, Weiss J, Riesner D, Willbold D, Birkmann E. Spontaneous and BSE-prion-seeded amyloid formation of full length recombinant bovine prion protein. Biochem Biophys Res Commun. 2008 Sep 5; 373(4):493-7. PMID: 18585368.
        View in: PubMed
      22. Panza G, Stöhr J, Birkmann E, Riesner D, Willbold D, Baba O, Terashima T, Dumpitak C. Aggregation and amyloid fibril formation of the prion protein is accelerated in the presence of glycogen. Rejuvenation Res. 2008 Apr; 11(2):365-9. PMID: 18341429.
        View in: PubMed
      23. Stöhr J, Weinmann N, Wille H, Kaimann T, Nagel-Steger L, Birkmann E, Panza G, Prusiner SB, Eigen M, Riesner D. Mechanisms of prion protein assembly into amyloid. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2409-14. PMID: 18268326; PMCID: PMC2268150.
      24. Wiesehan K, Stöhr J, Nagel-Steger L, van Groen T, Riesner D, Willbold D. Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide. Protein Eng Des Sel. 2008 Apr; 21(4):241-6. PMID: 18252750.
        View in: PubMed
      25. Leffers KW, Wille H, Stöhr J, Junger E, Prusiner SB, Riesner D. Assembly of natural and recombinant prion protein into fibrils. Biol Chem. 2005 Jun; 386(6):569-80. PMID: 16006244.
        View in: PubMed
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