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    Jean Paul Armache, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentBiochemistry and Biophysics
    Address600 16th Street
    San Francisco CA 94158
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Frauenfeld J, Löving R, Armache JP, Sonnen AF, Guettou F, Moberg P, Zhu L, Jegerschöld C, Flayhan A, Briggs JA, Garoff H, Löw C, Cheng Y, Nordlund P. A saposin-lipoprotein nanoparticle system for membrane proteins. Nat Methods. 2016 Apr; 13(4):345-51. PMID: 26950744.
        View in: PubMed
      2. Wu S, Armache JP, Cheng Y. Single-particle cryo-EM data acquisition by using direct electron detection camera. Microscopy (Oxf). 2016 Feb; 65(1):35-41. PMID: 26546989.
        View in: PubMed
      3. Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D. Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature. 2015 Sep 24; 525(7570):552. PMID: 26200340.
        View in: PubMed
      4. Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D. Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature. 2015 Apr 23; 520(7548):511-7. PMID: 25855297; PMCID: PMC4409540.
      5. Gogala M, Becker T, Beatrix B, Armache JP, Barrio-Garcia C, Berninghausen O, Beckmann R. Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion. Nature. 2014 Feb 6; 506(7486):107-10. PMID: 24499919.
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      6. Anger AM, Armache JP, Berninghausen O, Habeck M, Subklewe M, Wilson DN, Beckmann R. Structures of the human and Drosophila 80S ribosome. Nature. 2013 May 2; 497(7447):80-5. PMID: 23636399.
        View in: PubMed
      7. Armache JP, Anger AM, Márquez V, Franckenberg S, Fröhlich T, Villa E, Berninghausen O, Thomm M, Arnold GJ, Beckmann R, Wilson DN. Promiscuous behaviour of archaeal ribosomal proteins: implications for eukaryotic ribosome evolution. Nucleic Acids Res. 2013 Jan; 41(2):1284-93. PMID: 23222135; PMCID: PMC3553981.
      8. Grela P, Gajda MJ, Armache JP, Beckmann R, Krokowski D, Svergun DI, Grankowski N, Tchórzewski M. Solution structure of the natively assembled yeast ribosomal stalk determined by small-angle X-ray scattering. Biochem J. 2012 Jun 1; 444(2):205-9. PMID: 22458705.
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      9. Becker T, Franckenberg S, Wickles S, Shoemaker CJ, Anger AM, Armache JP, Sieber H, Ungewickell C, Berninghausen O, Daberkow I, Karcher A, Thomm M, Hopfner KP, Green R, Beckmann R. Structural basis of highly conserved ribosome recycling in eukaryotes and archaea. Nature. 2012 Feb 23; 482(7386):501-6. PMID: 22358840.
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      10. Jarasch A, Dziuk P, Becker T, Armache JP, Hauser A, Wilson DN, Beckmann R. The DARC site: a database of aligned ribosomal complexes. Nucleic Acids Res. 2012 Jan; 40(Database issue):D495-500. PMID: 22009674; PMCID: PMC3245104.
      11. Becker T, Armache JP, Jarasch A, Anger AM, Villa E, Sieber H, Motaal BA, Mielke T, Berninghausen O, Beckmann R. Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome. Nat Struct Mol Biol. 2011 Jun; 18(6):715-20. PMID: 21623367.
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      12. Márquez V, Fröhlich T, Armache JP, Sohmen D, Dönhöfer A, Mikolajka A, Berninghausen O, Thomm M, Beckmann R, Arnold GJ, Wilson DN. Proteomic characterization of archaeal ribosomes reveals the presence of novel archaeal-specific ribosomal proteins. J Mol Biol. 2011 Feb 4; 405(5):1215-32. PMID: 21134383.
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      13. Armache JP, Jarasch A, Anger AM, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Söding J, Westhof E, Wilson DN, Beckmann R. Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19748-53. PMID: 20980660; PMCID: PMC2993355.
      14. Armache JP, Jarasch A, Anger AM, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Söding J, Westhof E, Wilson DN, Beckmann R. Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19754-9. PMID: 20974910; PMCID: PMC2993421.
      15. Gartmann M, Blau M, Armache JP, Mielke T, Topf M, Beckmann R. Mechanism of eIF6-mediated inhibition of ribosomal subunit joining. J Biol Chem. 2010 May 14; 285(20):14848-51. PMID: 20356839; PMCID: PMC2865328.
      16. Bhushan S, Gartmann M, Halic M, Armache JP, Jarasch A, Mielke T, Berninghausen O, Wilson DN, Beckmann R. alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel. Nat Struct Mol Biol. 2010 Mar; 17(3):313-7. PMID: 20139981.
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      17. Becker T, Bhushan S, Jarasch A, Armache JP, Funes S, Jossinet F, Gumbart J, Mielke T, Berninghausen O, Schulten K, Westhof E, Gilmore R, Mandon EC, Beckmann R. Structure of monomeric yeast and mammalian Sec61 complexes interacting with the translating ribosome. Science. 2009 Dec 4; 326(5958):1369-73. PMID: 19933108; PMCID: PMC2920595.
      18. Seidelt B, Innis CA, Wilson DN, Gartmann M, Armache JP, Villa E, Trabuco LG, Becker T, Mielke T, Schulten K, Steitz TA, Beckmann R. Structural insight into nascent polypeptide chain-mediated translational stalling. Science. 2009 Dec 4; 326(5958):1412-5. PMID: 19933110; PMCID: PMC2920484.
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