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Jeff Lansman, PhD

TitleProfessor Emeritus
SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address513 Parnassus Avenue
San Francisco CA 94117
Phone415-476-1322
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    Collapse Biography 
    Collapse Awards and Honors
    Cambridge University1985National Science Foundation NATO Fellow
    Syntex Corporation1986Syntex Scholars Award
    March of Dimes Foundation1987Basil O'Connor Scholar Award
    Dartmouth Medical School1991Dunaway-Burnam Visiting Professor of Physiology
    UCSF School of Pharmacy2002Long Prize "Teacher of the Year"
    UCSF School of Pharmacy2004Joseph M. Long Prize for Excellence in Teaching
    UCSF School of Pharmacy2004Long Prize "Teacher of the Year"
    UCSF School of Pharmacy2006Joseph M. Long Foundation Prize for Excellence in Teaching
    UCSF School of Pharmacy 2007Long Prize "Teacher of the Year"
    UCSF School of Pharmacy2008Long Prize "Teacher of the Year"
    UCSF School of Pharmacy2009Joseph M. Long Foundation Prize for Excellence in Teaching
    American Association of Colleges of Pharmacy2009AACP Teacher of the Year
    UCSF School of Pharmacy2010Joseph M. Long Foundation Prize for Excellence in Teaching
    American Association of Colleges of Pharmacy2010AACP Teacher of the Year
    UCSF School of Pharmacy2011Long Prize "Teacher of the Year"
    UCSF School of Pharmacy2013Joseph M. Long Foundation Prize for Excellence in Teaching

    Collapse Research 
    Collapse Research Activities and Funding
    VASCULAR ION TRANSPORT MECHANISMS
    NIH R01HL038484Apr 1, 1988 - Mar 31, 1991
    Role: Principal Investigator
    REGULATION OF NEURONAL CALCIUM CHANNELS
    NIH R01NS023720Feb 1, 1988 - May 31, 2002
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Lansman JB. Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle. Channels (Austin). 2015; 9(3):145-60. PMID: 25941878; PMCID: PMC4594363.
    2. Tan N, Lansman JB. Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle. J Physiol. 2014 Aug 01; 592(15):3303-23. PMID: 24879867; PMCID: PMC4146377.
    3. Vasquez I, Tan N, Boonyasampant M, Koppitch KA, Lansman JB. Partial opening and subconductance gating of mechanosensitive ion channels in dystrophic skeletal muscle. J Physiol. 2012 Dec 01; 590(23):6167-85. PMID: 22966155; PMCID: PMC3530124.
    4. Ho TC, Horn NA, Huynh T, Kelava L, Lansman JB. Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers. Channels (Austin). 2012 Jul-Aug; 6(4):246-54. PMID: 22785252; PMCID: PMC3508903.
    5. Lansman JB. Mechanosensitive ion channels in dystrophic muscle. Curr Top Membr. 2007; 59:467-84. PMID: 25168146.
      View in: PubMed
    6. Lansman JB, Franco-Obregón A. Mechanosensitive ion channels in skeletal muscle: a link in the membrane pathology of muscular dystrophy. Clin Exp Pharmacol Physiol. 2006 Jul; 33(7):649-56. PMID: 16789935.
      View in: PubMed
    7. Franco-Obregón A, Lansman JB. Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse. J Physiol. 2002 Mar 01; 539(Pt 2):391-407. PMID: 11882673; PMCID: PMC2290167.
    8. Chavis P, Fagni L, Lansman JB, Bockaert J. Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature. 1996 Aug 22; 382(6593):719-22. PMID: 8751443.
      View in: PubMed
    9. Parri HR, Lansman JB. Multiple components of Ca2+ channel facilitation in cerebellar granule cells: expression of facilitation during development in culture. J Neurosci. 1996 Aug 15; 16(16):4890-902. PMID: 8756421.
      View in: PubMed
    10. Slesinger PA, Lansman JB. Reopening of single L-type Ca2+ channels in mouse cerebellar granule cells: dependence on voltage and ion concentration. J Physiol. 1996 Mar 01; 491 ( Pt 2):335-45. PMID: 8866858; PMCID: PMC1158729.
    11. Haws CM, Winegar BD, Lansman JB. Block of single L-type Ca2+ channels in skeletal muscle fibers by aminoglycoside antibiotics. J Gen Physiol. 1996 Mar; 107(3):421-32. PMID: 8868052; PMCID: PMC2216997.
    12. Winegar BD, Haws CM, Lansman JB. Subconductance block of single mechanosensitive ion channels in skeletal muscle fibers by aminoglycoside antibiotics. J Gen Physiol. 1996 Mar; 107(3):433-43. PMID: 8868053; PMCID: PMC2216990.
    13. Franco-Obregón A, Lansman JB. Spontaneous opening of the acetylcholine receptor channel in developing muscle cells from normal and dystrophic mice. J Neurosci Res. 1995 Nov 01; 42(4):452-8. PMID: 8568931.
      View in: PubMed
    14. Chavis P, Fagni L, Bockaert J, Lansman JB. Modulation of calcium channels by metabotropic glutamate receptors in cerebellar granule cells. Neuropharmacology. 1995 Aug; 34(8):929-37. PMID: 8532174.
      View in: PubMed
    15. Elam TR, Lansman JB. The role of Mg2+ in the inactivation of inwardly rectifying K+ channels in aortic endothelial cells. J Gen Physiol. 1995 Apr; 105(4):463-84. PMID: 7608654; PMCID: PMC2216934.
    16. Franco-Obregón A, Lansman JB. Mechanosensitive ion channels in skeletal muscle from normal and dystrophic mice. J Physiol. 1994 Dec 01; 481 ( Pt 2):299-309. PMID: 7537813; PMCID: PMC1155930.
    17. Haws CM, Slesinger PA, Lansman JB. Dihydropyridine- and omega-conotoxin-sensitive Ca2+ currents in cerebellar neurons: persistent block of L-type channels by a pertussis toxin-sensitive G-protein. J Neurosci. 1993 Mar; 13(3):1148-56. PMID: 8382734.
      View in: PubMed
    18. Slesinger PA, Lansman J. Reopening of Ca2+ channels in mouse cerebellar neurons at resting membrane potentials during recovery from inactivation. Neuron. 1991 Nov; 7(5):755-62. PMID: 1660284.
      View in: PubMed
    19. Lansman J, Franco A. What does dystrophin do in normal muscle? J Muscle Res Cell Motil. 1991 Oct; 12(5):409-11. PMID: 1658040.
      View in: PubMed
    20. Haws CM, Lansman J. Developmental regulation of mechanosensitive calcium channels in skeletal muscle from normal and mdx mice. Proc Biol Sci. 1991 Sep 23; 245(1314):173-7. PMID: 1684042.
      View in: PubMed
    21. Slesinger PA, Lansman J. Inactivating and non-inactivating dihydropyridine-sensitive Ca2+ channels in mouse cerebellar granule cells. J Physiol. 1991 Aug; 439:301-23. PMID: 1654414; PMCID: PMC1180110.
    22. Haws CM, Lansman J. Calcium-permeable ion channels in cerebellar neurons from mdx mice. Proc Biol Sci. 1991 Jun 22; 244(1311):185-9. PMID: 1679936.
      View in: PubMed
    23. Franco A, Winegar BD, Lansman J. Open channel block by gadolinium ion of the stretch-inactivated ion channel in mdx myotubes. Biophys J. 1991 Jun; 59(6):1164-70. PMID: 1714778; PMCID: PMC1281197.
    24. Slesinger PA, Lansman J. Inactivation of calcium currents in granule cells cultured from mouse cerebellum. J Physiol. 1991 Apr; 435:101-21. PMID: 1663157; PMCID: PMC1181452.
    25. Winegar BD, Kelly R, Lansman J. Block of current through single calcium channels by Fe, Co, and Ni. Location of the transition metal binding site in the pore. J Gen Physiol. 1991 Feb; 97(2):351-67. PMID: 1849961; PMCID: PMC2216478.
    26. Forsayeth JR, Franco A, Rossi AB, Lansman J, Hall ZW. Expression of functional mouse muscle acetylcholine receptors in Chinese hamster ovary cells. J Neurosci. 1990 Aug; 10(8):2771-9. PMID: 2388086.
      View in: PubMed
    27. Gu Y, Franco A, Gardner PD, Lansman J, Forsayeth JR, Hall ZW. Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells. Neuron. 1990 Aug; 5(2):147-57. PMID: 2383398.
      View in: PubMed
    28. Franco A, Lansman J. Stretch-sensitive channels in developing muscle cells from a mouse cell line. J Physiol. 1990 Aug; 427:361-80. PMID: 2170636; PMCID: PMC1189935.
    29. Winegar BD, Lansman J. Voltage-dependent block by zinc of single calcium channels in mouse myotubes. J Physiol. 1990 Jun; 425:563-78. PMID: 2170633; PMCID: PMC1189863.
    30. Franco A, Lansman J. Calcium entry through stretch-inactivated ion channels in mdx myotubes. Nature. 1990 Apr 12; 344(6267):670-3. PMID: 1691450.
      View in: PubMed
    31. Lansman J. Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. J Gen Physiol. 1990 Apr; 95(4):679-96. PMID: 2159974; PMCID: PMC2216337.
    32. Lansman J. Endothelial mechanosensors. Going with the flow. Nature. 1988 Feb 11; 331(6156):481-2. PMID: 2448647.
      View in: PubMed
    33. Lansman J. Calcium current and calcium-activated inward current in the oocyte of the starfish Leptasterias hexactis. J Physiol. 1987 Sep; 390:397-413. PMID: 2450996; PMCID: PMC1192188.
    34. Lansman J, Hallam TJ, Rink TJ. Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers? Nature. 1987 Feb 26-Mar 4; 325(6107):811-3. PMID: 2434860.
      View in: PubMed
    35. Hess P, Lansman J, Tsien RW. Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells. J Gen Physiol. 1986 Sep; 88(3):293-319. PMID: 2428919; PMCID: PMC2228831.
    36. Lansman J, Hess P, Tsien RW. Blockade of current through single calcium channels by Cd2+, Mg2+, and Ca2+. Voltage and concentration dependence of calcium entry into the pore. J Gen Physiol. 1986 Sep; 88(3):321-47. PMID: 2428920; PMCID: PMC2228830.
    37. Tsien RW, Bean BP, Hess P, Lansman J, Nilius B, Nowycky MC. Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. J Mol Cell Cardiol. 1986 Jul; 18(7):691-710. PMID: 2427730.
      View in: PubMed
    38. Hess P, Lansman J, Nilius B, Tsien RW. Calcium channel types in cardiac myocytes: modulation by dihydropyridines and beta-adrenergic stimulation. J Cardiovasc Pharmacol. 1986; 8 Suppl 9:S11-21. PMID: 2433538.
      View in: PubMed
    39. Nilius B, Hess P, Lansman J, Tsien RW. A novel type of cardiac calcium channel in ventricular cells. Biomed Biochim Acta. 1986; 45(1-2):S167-70. PMID: 2421713.
      View in: PubMed
    40. Nilius B, Hess P, Lansman J, Tsien RW. A novel type of cardiac calcium channel in ventricular cells. Nature. 1985 Aug 1-7; 316(6027):443-6. PMID: 2410797.
      View in: PubMed
    41. Hess P, Lansman JB, Tsien RW. Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature. 1984 Oct 11-17; 311(5986):538-44. PMID: 6207437.
      View in: PubMed
    42. Lansman JB. Voltage-clamp study of the conductance activated at fertilization in the starfish egg. J Physiol. 1983 Dec; 345:353-72. PMID: 6663505; PMCID: PMC1193801.
    43. Moody WJ, Lansman JB. Developmental regulation of Ca2+ and K+ currents during hormone-induced maturation of starfish oocytes. Proc Natl Acad Sci U S A. 1983 May; 80(10):3096-100. PMID: 6574473; PMCID: PMC393981.
    44. Carraway R, Cochrane DE, Lansman JB, Leeman SE, Paterson BM, Welch HJ. Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. J Physiol. 1982 Feb; 323:403-14. PMID: 6178820; PMCID: PMC1250364.
    45. Cochrane DE, Distel DL, Lansman JB, Paterson BM. Stimulus-secretion coupling in rat mast cells: inactivation of extracellular calcium dependent secretion. J Physiol. 1982 Feb; 323:423-35. PMID: 6178821; PMCID: PMC1250366.
    46. Lansman JB, Cochrane DE. Wheat germ agglutinin stimulates exocytotic histamine secretion from rat mast cells in the absence of extracellular calcium. Biochem Pharmacol. 1980 Feb; 29(3):455-8. PMID: 6153896.
      View in: PubMed
    47. Haynes DH, Lansman J, Cahill AL, Morris SJ. Kinetics of cation-induced aggregation of Torpedo electric organ synaptic vesicles. Biochim Biophys Acta. 1979 Nov 02; 557(2):340-53. PMID: 497186.
      View in: PubMed
    48. Lansman J, Haynes DH. Charge asymmetry does not affect the rate of Ca2+-induced aggregation of phospholipid vesicles. Biophys J. 1979 May; 26(2):335-7. PMID: 262421; PMCID: PMC1328525.
    49. Lansman J, Haynes DH. Kinetics of a Ca-2+-triggered membrane aggregation reaction of phospholipid membranes. Biochim Biophys Acta. 1975 Jul 03; 394(3):335-47. PMID: 1131369.
      View in: PubMed
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