Jennifer Graves, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.A.S. in Clinical Research2013 Graduate Division (Advance Training in Clinical Research)
    University of California, San FranciscoFellowship2012Multiple Sclerosis
    University of PennsylvaniaFellowship2011Neuro-ophthalmology
    University of PennsylvaniaResidency2010Neurology
    UT SouthwesternM.D., Ph.D.2006Departments of Medicine and Molecular Biophysics

    Collapse Overview 
    Collapse Overview
    Dr.Graves is a board certified neurologist with subspecialty training in multiple sclerosis and neuro-ophthalmology. She takes care of patients in both the adult and pediatric MS Centers.

    Collapse ORNG Applications 
    Collapse In The News
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2018 Jan 01; 1352458517747407. PMID: 29310490.
      View in: PubMed
    2. Graves JS, Chitnis T, Weinstock-Guttman B, Rubin J, Zelikovitch AS, Nourbakhsh B, Simmons T, Waltz M, Casper TC, Waubant E. Maternal and Perinatal Exposures Are Associated With Risk for Pediatric-Onset Multiple Sclerosis. Pediatrics. 2017 Apr; 139(4). PMID: 28562303.
      View in: PubMed
    3. Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Neurology. 2017 Apr 25; 88(17):1623-1629. PMID: 28356466.
      View in: PubMed
    4. Block VJ, Lizée A, Crabtree-Hartman E, Bevan CJ, Graves JS, Bove R, Green AJ, Nourbakhsh B, Tremblay M, Gourraud PA, Ng MY, Pletcher MJ, Olgin JE, Marcus GM, Allen DD, Cree BA, Gelfand JM. Continuous daily assessment of multiple sclerosis disability using remote step count monitoring. J Neurol. 2017 Feb; 264(2):316-326. PMID: 27896433.
      View in: PubMed
    5. Chitnis T, Graves J, Weinstock-Guttman B, Belman A, Olsen C, Misra M, Aaen G, Benson L, Candee M, Gorman M, Greenberg B, Krupp L, Lotze T, Mar S, Ness J, Rose J, Rubin J, Schreiner T, Tillema J, Waldman A, Rodriguez M, Casper C, Waubant E. Distinct effects of obesity and puberty on risk and age at onset of pediatric MS. Ann Clin Transl Neurol. 2016 Dec; 3(12):897-907. PMID: 28097202.
      View in: PubMed
    6. Hatcher SE, Waubant E, Graves JS. Rebound Syndrome in Multiple Sclerosis After Fingolimod Cessation-Reply. JAMA Neurol. 2016 Nov 01; 73(11):1376. PMID: 27669526.
      View in: PubMed
    7. Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Spencer CM, Lynch SV, Zamvil SS, Waubant E. Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls. BMC Neurol. 2016 Sep 21; 16(1):182. PMID: 27652609.
      View in: PubMed
    8. Yeh EA, Graves JS, Benson LA, Wassmer E, Waldman A. Pediatric optic neuritis. Neurology. 2016 Aug 30; 87(9 Suppl 2):S53-8. PMID: 27572862.
      View in: PubMed
    9. Hanumanthe SB, Francisco C, Hart J, Graves J, Waubant E. Biopsy-Supported Tumefactive Demyelination of the Central Nervous System in Children. J Child Neurol. 2016 Dec; 31(14):1528-1533. PMID: 27572815.
      View in: PubMed
    10. Cree B, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL, et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Oct; 80(4):499-510. PMID: 27464262.
      View in: PubMed
    11. Graves JS. Is Season of Birth Important for Multiple Sclerosis Risk? JAMA Neurol. 2016 Aug 01; 73(8):912-3. PMID: 27367302.
      View in: PubMed
    12. Francisco C, Graves J, Waubant E. Clinical trials for pediatric MS should be prioritized to test only one or two of the most promising agents - NO. Mult Scler. 2016 Nov; 22(13):1651-1653. PMID: 27473402.
      View in: PubMed
    13. Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A. Sex differences and subclinical retinal injury in pediatric-onset MS. Mult Scler. 2017 Mar; 23(3):447-455. PMID: 27306618.
      View in: PubMed
    14. Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, Weinstock-Guttman B, Casper TC. Characteristics of Children and Adolescents With Multiple Sclerosis. Pediatrics. 2016 Jul; 138(1). PMID: 27358474; PMCID: PMC4925083 [Available on 07/01/17].
    15. Hatcher SE, Waubant E, Nourbakhsh B, Crabtree-Hartman E, Graves J. Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment. JAMA Neurol. 2016 Jul 01; 73(7):790-4. PMID: 27135594.
      View in: PubMed
    16. Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos L, Waubant E. Dietary salt intake and time to relapse in paediatric multiple sclerosis. J Neurol Neurosurg Psychiatry. 2016 Dec; 87(12):1350-1353. PMID: 27343226.
      View in: PubMed
    17. Tremlett H, Fadrosh DW, Faruqi AA, Zhu F, Hart J, Roalstad S, Graves J, Lynch S, Waubant E. Gut microbiota in early pediatric multiple sclerosis: a case-control study. Eur J Neurol. 2016 Aug; 23(8):1308-1321. PMID: 27176462; PMCID: PMC4955679 [Available on 08/01/17].
    18. Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Lynch S, Waubant E. Gut microbiota composition and relapse risk in pediatric MS: A pilot study. J Neurol Sci. 2016 Apr 15; 363:153-7. PMID: 27000242; PMCID: PMC4806409 [Available on 04/15/17].
    19. McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2016 Mar; 6:87-92. PMID: 27063630; PMCID: PMC4830915 [Available on 03/01/17].
    20. Graves J, Barcellos LF, Shao X, Noble J, Mowry EM, Quach H, Belman A, Casper TC, Krupp LB, Waubant E. Genetic predictors of relapse rate in pediatric MS. Mult Scler. 2016 Oct; 22(12):1528-1535. PMID: 26769066.
      View in: PubMed
    21. Chohan H, Greenfield AL, Yadav V, Graves J. Use of Cannabinoids for Spasticity and Pain Management in MS. Curr Treat Options Neurol. 2016 Jan; 18(1):1. PMID: 26705757.
      View in: PubMed
    22. Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC. Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report. Neurology. 2016 Jan 19; 86(3):245-52. PMID: 26683648; PMCID: PMC4733158.
    23. Graves J. In retrospect: Twenty-five years of the sex-determining gene. Nature. 2015 Dec 17; 528(7582):343-4. PMID: 26672550.
      View in: PubMed
    24. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug; 72(8):897-904. PMID: 26053119.
      View in: PubMed
    25. Lulu S, Graves J, Waubant E. Menarche increases relapse risk in pediatric multiple sclerosis. Mult Scler. 2016 Feb; 22(2):193-200. PMID: 25948626; PMCID: PMC4636485 [Available on 02/01/17].
    26. Maghzi AH, Graves J, Revirajan N, Spain R, Liu S, McCulloch CE, Pelletier D, Green AJ, Waubant E. Retinal axonal loss in very early stages of multiple sclerosis. Eur J Neurol. 2015 Jul; 22(7):1138-41. PMID: 25929276.
      View in: PubMed
    27. Weinfurtner K, Graves J, Ness J, Krupp L, Milazzo M, Waubant E. Prolonged Remission in Neuromyelitis Optica Following Cessation of Rituximab Treatment. J Child Neurol. 2015 Sep; 30(10):1366-70. PMID: 25387545.
      View in: PubMed
    28. Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18; 83(21):1923-9. PMID: 25339213; PMCID: PMC4248458.
    29. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42. PMID: 25263997; PMCID: PMC4214886.
    30. Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y. The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps. J Child Neurol. 2015 Sep; 30(10):1381-7. PMID: 25270659; PMCID: PMC4379142.
    31. Graves J, Kraus V, Soares BP, Hess CP, Waubant E. Longitudinally extensive optic neuritis in pediatric patients. J Child Neurol. 2015 Jan; 30(1):120-3. PMID: 24563470.
      View in: PubMed
    32. Beres SJ, Graves J, Waubant E. Rituximab use in pediatric central demyelinating disease. Pediatr Neurol. 2014 Jul; 51(1):114-8. PMID: 24768216.
      View in: PubMed
    33. Graves J, Vinayagasundaram U, Mowry EM, Matthews IR, Marino JA, Cheng J, Waubant E. Effects of rituximab on lymphocytes in multiple sclerosis and neuromyelitis optica. Mult Scler Relat Disord. 2014 Mar; 3(2):244-52. PMID: 25878012.
      View in: PubMed
    34. Graves J, Galetta SL, Palmer J, Margolin DH, Rizzo M, Bilbruck J, Balcer LJ. Alemtuzumab improves contrast sensitivity in patients with relapsing-remitting multiple sclerosis. Mult Scler. 2013 Sep; 19(10):1302-9. PMID: 23459567; PMCID: PMC3807733.
    35. Galetta KM, Graves J, Talman LS, Lile DJ, Frohman EM, Calabresi PA, Galetta SL, Balcer LJ. Visual pathway axonal loss in benign multiple sclerosis: a longitudinal study. J Neuroophthalmol. 2012 Jun; 32(2):116-23. PMID: 22269944; PMCID: PMC3427935.
    36. Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ. Microcystic macular oedema in multiple sclerosis is associated with disease severity. Brain. 2012 Jun; 135(Pt 6):1786-93. PMID: 22539259; PMCID: PMC3359753.
    37. Graves JS, Galetta SL. Acute visual loss and other neuro-ophthalmologic emergencies: management. Neurol Clin. 2012 Feb; 30(1):75-99, viii. PMID: 22284056.
      View in: PubMed
    38. Chaumeil J, Waters PD, Koina E, Gilbert C, Robinson TJ, Graves J. Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals. PLoS One. 2011 Apr 25; 6(4):e19040. PMID: 21541345; PMCID: PMC3081832.
    39. Graves J, Balcer LJ. Eye disorders in patients with multiple sclerosis: natural history and management. Clin Ophthalmol. 2010 Dec 06; 4:1409-22. PMID: 21188152; PMCID: PMC3000766.
    40. Graves JA, Rothermund K, Wang T, Qian W, Van Houten B, Prochownik EV. Point mutations in c-Myc uncouple neoplastic transformation from multiple other phenotypes in rat fibroblasts. PLoS One. 2010 Oct 28; 5(10):e13717. PMID: 21060841; PMCID: PMC2965668.
    41. Frohman TC, Graves J, Balcer LJ, Galetta SL, Frohman EM. The neuro-ophthalmology of multiple sclerosis. Continuum (Minneap Minn). 2010 Oct; 16(5 Multiple Sclerosis):122-46. PMID: 22810602.
      View in: PubMed
    42. Turkeltaub PE, Graves J. Teaching neuroimages: hemorrhage associated with reversible posterior leukoencephalopathy syndrome. Neurology. 2009 Aug 11; 73(6):e30. PMID: 19667315.
      View in: PubMed
    43. Graves JA, Metukuri M, Scott D, Rothermund K, Prochownik EV. Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc. J Biol Chem. 2009 Mar 06; 284(10):6520-9. PMID: 19098005; PMCID: PMC2649099.
    44. Deakin JE, Koina E, Waters PD, Doherty R, Patel VS, Delbridge ML, Dobson B, Fong J, Hu Y, van den Hurk C, Pask AJ, Shaw G, Smith C, Thompson K, Wakefield MJ, Yu H, Renfree MB, Graves JA. Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammals. Chromosome Res. 2008; 16(8):1159-75. PMID: 18987984.
      View in: PubMed
    45. Patel VS, Cooper SJ, Deakin JE, Fulton B, Graves T, Warren WC, Wilson RK, Graves JA. Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals. BMC Biol. 2008 Jul 25; 6:34. PMID: 18657265; PMCID: PMC2529266.
    46. Pumir A, Graves J, Ranganathan R, Shraiman BI. Systems analysis of the single photon response in invertebrate photoreceptors. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10354-9. PMID: 18653755; PMCID: PMC2492478.
    47. Janes DE, Ezaz T, Graves J, Edwards SV. Characterization, chromosomal location, and genomic neighborhood of a ratite ortholog of a gene with gonadal expression in mammals. Integr Comp Biol. 2008 Oct; 48(4):505-11. PMID: 21669811.
      View in: PubMed
    48. Mishra P, Socolich M, Wall MA, Graves J, Wang Z, Ranganathan R. Dynamic scaffolding in a G protein-coupled signaling system. Cell. 2007 Oct 05; 131(1):80-92. PMID: 17923089.
      View in: PubMed
    49. Deakin JE, Papenfuss AT, Belov K, Cross JG, Coggill P, Palmer S, Sims S, Speed TP, Beck S, Graves JA. Evolution and comparative analysis of the MHC Class III inflammatory region. BMC Genomics. 2006 Nov 02; 7:281. PMID: 17081307; PMCID: PMC1654159.
    50. Rapkins RW, Hore T, Smithwick M, Ager E, Pask AJ, Renfree MB, Kohn M, Hameister H, Nicholls RD, Deakin JE, Graves JA. Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet. 2006 Oct; 2(10):e182. PMID: 17069464; PMCID: PMC1626109.
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