Jeremiah Osteen, PhD

SchoolUCSF School of Medicine
Address600 16th Street
San Francisco CA 94158
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    Toxins as molecular probes of pain transduction mechanisms
    NIH F32NS081907Sep 30, 2012 - Jul 29, 2015
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. 2016 Jun 23; 534(7608):494-9. PMID: 27281198.
      View in: PubMed
    2. Osteen JD, Barro-Soria R, Robey S, Sampson KJ, Kass RS, Larsson HP. Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels. Proc Natl Acad Sci U S A. 2012 May 1; 109(18):7103-8. PMID: 22509038; PMCID: PMC3344993.
    3. Glaaser IW, Osteen JD, Puckerin A, Sampson KJ, Jin X, Kass RS. Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nat Commun. 2012; 3:706. PMID: 22426227; PMCID: PMC3518026.
    4. Chan PJ, Osteen JD, Xiong D, Bohnen MS, Doshi D, Sampson KJ, Marx SO, Karlin A, Kass RS. Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1. J Gen Physiol. 2012 Feb; 139(2):135-44. PMID: 22250012; PMCID: PMC3269792.
    5. Wang K, Terrenoire C, Sampson KJ, Iyer V, Osteen JD, Lu J, Keller G, Kotton DN, Kass RS. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. J Physiol. 2011 Dec 15; 589(Pt 24):6093-104. PMID: 22025662; PMCID: PMC3286688.
    6. Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22710-5. PMID: 21149716; PMCID: PMC3012494.
    7. Osteen JD, Sampson KJ, Kass RS. The cardiac IKs channel, complex indeed. Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44):18751-2. PMID: 20974964; PMCID: PMC2973886.
    8. Osteen JD, Mindell JA. Insights into the ClC-4 transport mechanism from studies of Zn2+ inhibition. Biophys J. 2008 Nov 15; 95(10):4668-75. PMID: 18658230; PMCID: PMC2576391.
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