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    Jill Ostrem, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentNeurology
    Address1635 Divisadero Street
    San Francisco CA 94143
    Phone415-353-2311

       Biography 
       Education and Training
      Institution Degree School or Department Year
      George Washington UniversityM.D.School of Medicine1998

       ORNG Applications 
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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Starr PA, Markun LC, Larson PS, Volz MM, Martin AJ, Ostrem JL. Interventional MRI-guided deep brain stimulation in pediatric dystonia: first experience with the ClearPoint system. J Neurosurg Pediatr. 2014 Oct; 14(4):400-8.
        View in: PubMed
      2. Ostrem JL, Markun LC, Glass GA, Racine CA, Volz MM, Heath SL, de Hemptinne C, Starr PA. Effect of frequency on subthalamic nucleus deep brain stimulation in primary dystonia. Parkinsonism Relat Disord. 2014 Apr; 20(4):432-8.
        View in: PubMed
      3. Mills KA, Starr PA, Ostrem JL. Neuromodulation for dystonia: target and patient selection. Neurosurg Clin N Am. 2014 Jan; 25(1):59-75.
        View in: PubMed
      4. Starr PA, Ostrem JL. Commentary on "Adaptive deep brain stimulation in advanced Parkinson disease". Ann Neurol. 2013 Sep; 74(3):447-8.
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      5. Katz M, Byl NN, San Luciano M, Ostrem JL. Focal task-specific lower extremity dystonia associated with intense repetitive exercise: A case series. Parkinsonism Relat Disord. 2013 Nov; 19(11):1033-8.
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      6. Witt JL, Moro E, Ash RS, Hamani C, Starr PA, Lozano AM, Hodaie M, Poon YY, Markun LC, Ostrem JL. Predictive factors of outcome in primary cervical dystonia following pallidal deep brain stimulation. Mov Disord. 2013 Sep; 28(10):1451-5.
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      7. Shimamoto SA, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Miller KJ, Starr PA. Subthalamic nucleus neurons are synchronized to primary motor cortex local field potentials in Parkinson's disease. J Neurosci. 2013 Apr 24; 33(17):7220-33.
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      8. Witt J, Starr PA, Ostrem JL. Use of pallidal deep brain stimulation in postinfarct hemidystonia. Stereotact Funct Neurosurg. 2013; 91(4):243-7.
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      9. de Hemptinne C, Ryapolova-Webb ES, Air EL, Garcia PA, Miller KJ, Ojemann JG, Ostrem JL, Galifianakis NB, Starr PA. Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4780-5.
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      10. Ostrem JL, Galifianakis NB, Markun LC, Grace JK, Martin AJ, Starr PA, Larson PS. Clinical outcomes of PD patients having bilateral STN DBS using high-field interventional MR-imaging for lead placement. Clin Neurol Neurosurg. 2013 Jun; 115(6):708-12.
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      11. Kilbane C, Ostrem J, Galifianakis N, Grace J, Markun L, Glass GA. Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia. Tremor Other Hyperkinet Mov (N Y). 2012; 2.
        View in: PubMed
      12. Mills KA, Scherzer R, Starr PA, Ostrem JL. Weight change after globus pallidus internus or subthalamic nucleus deep brain stimulation in Parkinson's disease and dystonia. Stereotact Funct Neurosurg. 2012; 90(6):386-93.
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      13. Markun LC, Starr PA, Air EL, Marks WJ, Volz MM, Ostrem JL. Shorter disease duration correlates with improved long-term deep brain stimulation outcomes in young-onset DYT1 dystonia. Neurosurgery. 2012 Aug; 71(2):325-30.
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      14. Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA. Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor. Clin Neurophysiol. 2012 Nov; 123(11):2232-8.
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      15. Crowell AL, Ryapolova-Webb ES, Ostrem JL, Galifianakis NB, Shimamoto S, Lim DA, Starr PA. Oscillations in sensorimotor cortex in movement disorders: an electrocorticography study. Brain. 2012 Feb; 135(Pt 2):615-30.
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      16. Christine CW, Marks WJ, Ostrem JL. Development of Parkinson's disease in patients with Narcolepsy. J Neural Transm. 2012 Jun; 119(6):697-9.
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      17. Air EL, Ostrem JL, Sanger TD, Starr PA. Deep brain stimulation in children: experience and technical pearls. J Neurosurg Pediatr. 2011 Dec; 8(6):566-74.
        View in: PubMed
      18. Ostrem JL, Racine CA, Glass GA, Grace JK, Volz MM, Heath SL, Starr PA. Subthalamic nucleus deep brain stimulation in primary cervical dystonia. Neurology. 2011 Mar 8; 76(10):870-8.
        View in: PubMed
      19. Isaias IU, Volkmann J, Kupsch A, Burgunder JM, Ostrem JL, Alterman RL, Mehdorn HM, Schönecker T, Krauss JK, Starr P, Reese R, Kühn AA, Schüpbach WM, Tagliati M. Factors predicting protracted improvement after pallidal DBS for primary dystonia: the role of age and disease duration. J Neurol. 2011 Aug; 258(8):1469-76.
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      20. Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, Tagliati M, Alterman R, Stern M, Baltuch G, Starr PA, Larson PS, Ostrem JL, Nutt J, Kieburtz K, Kordower JH, Olanow CW. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. Lancet Neurol. 2010 Dec; 9(12):1164-72.
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      21. Chang EF, Schrock LE, Starr PA, Ostrem JL. Long-term benefit sustained after bilateral pallidal deep brain stimulation in patients with refractory tardive dystonia. Stereotact Funct Neurosurg. 2010; 88(5):304-10.
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      22. Timmermann L, Pauls KA, Wieland K, Jech R, Kurlemann G, Sharma N, Gill SS, Haenggeli CA, Hayflick SJ, Hogarth P, Leenders KL, Limousin P, Malanga CJ, Moro E, Ostrem JL, Revilla FJ, Santens P, Schnitzler A, Tisch S, Valldeoriola F, Vesper J, Volkmann J, Woitalla D, Peker S. Dystonia in neurodegeneration with brain iron accumulation: outcome of bilateral pallidal stimulation. Brain. 2010 Mar; 133(Pt 3):701-12.
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      23. Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS. Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy. J Neurosurg. 2010 Mar; 112(3):479-90.
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      24. Ostrem JL, Galifianakis NB. Overview of common movement disorders. Continuum (Minneap Minn). 2010 Feb; 16(1 Movement Disorders):13-48.
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      25. Schrock LE, Ostrem JL. A child with progressive dystonia, dysarthria, and spasticity. Rev Neurol Dis. 2010; 7(1):32-3; discussion 39-42.
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      26. Ostrem JL, Christine CW, Glass GA, Schrock LE, Starr PA. Pedunculopontine nucleus deep brain stimulation in a patient with primary progressive freezing gait disorder. Stereotact Funct Neurosurg. 2010; 88(1):51-5.
        View in: PubMed
      27. Schrock LE, Ostrem JL, Turner RS, Shimamoto SA, Starr PA. The subthalamic nucleus in primary dystonia: single-unit discharge characteristics. J Neurophysiol. 2009 Dec; 102(6):3740-52.
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      28. Shimamoto SA, Larson PS, Ostrem JL, Glass GA, Turner RS, Starr PA. Physiological identification of the human pedunculopontine nucleus. J Neurol Neurosurg Psychiatry. 2010 Jan; 81(1):80-6.
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      29. Richardson RM, Ostrem JL, Starr PA. Surgical repositioning of misplaced subthalamic electrodes in Parkinson's disease: location of effective and ineffective leads. Stereotact Funct Neurosurg. 2009; 87(5):297-303.
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      30. Glass GA, Ku S, Ostrem JL, Heath S, Larson PS. Fluoroscopic, EMG-guided injection of botulinum toxin into the longus colli for the treatment of anterocollis. Parkinsonism Relat Disord. 2009 Sep; 15(8):610-3.
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      31. Berman BD, Starr PA, Marks WJ, Ostrem JL. Induction of bradykinesia with pallidal deep brain stimulation in patients with cranial-cervical dystonia. Stereotact Funct Neurosurg. 2009; 87(1):37-44.
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      32. Martin AJ, Larson PS, Ostrem JL, Starr PA. Interventional magnetic resonance guidance of deep brain stimulator implantation for Parkinson disease. Top Magn Reson Imaging. 2009 Jan; 19(4):213-21.
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      33. Sani S, Ostrem JL, Shimamoto S, Levesque N, Starr PA. Single unit "pauser" characteristics of the globus pallidus pars externa distinguish primary dystonia from secondary dystonia and Parkinson's disease. Exp Neurol. 2009 Apr; 216(2):295-9.
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      34. Marks WJ, Ostrem JL, Verhagen L, Starr PA, Larson PS, Bakay RA, Taylor R, Cahn-Weiner DA, Stoessl AJ, Olanow CW, Bartus RT. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol. 2008 May; 7(5):400-8.
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      35. Ostrem JL, Starr PA. Treatment of dystonia with deep brain stimulation. Neurotherapeutics. 2008 Apr; 5(2):320-30.
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      36. Chang EF, Turner RS, Ostrem JL, Davis VR, Starr PA. Neuronal responses to passive movement in the globus pallidus internus in primary dystonia. J Neurophysiol. 2007 Dec; 98(6):3696-707.
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      37. Ostrem JL, Marks WJ, Volz MM, Heath SL, Starr PA. Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome). Mov Disord. 2007 Oct 15; 22(13):1885-91.
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      38. Starr PA, Barbaro NM, Raskin NH, Ostrem JL. Chronic stimulation of the posterior hypothalamic region for cluster headache: technique and 1-year results in four patients. J Neurosurg. 2007 Jun; 106(6):999-1005.
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      39. Lim DA, Khandhar SM, Heath S, Ostrem JL, Ringel N, Starr P. Multiple target deep brain stimulation for multiple sclerosis related and poststroke Holmes' tremor. Stereotact Funct Neurosurg. 2007; 85(4):144-9.
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      40. Starr PA, Turner RS, Rau G, Lindsey N, Heath S, Volz M, Ostrem JL, Marks WJ. Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes. J Neurosurg. 2006 Apr; 104(4):488-501.
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      41. Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA. Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005 Nov; 54(5):1107-14.
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      42. Ostrem JL, Kang GA, Subramanian I, Guarnieri M, Hubble J, Rabinowicz AL, Bronstein J. The effect of entacapone on homocysteine levels in Parkinson disease. Neurology. 2005 Apr 26; 64(8):1482.
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      43. Starr PA, Rau GM, Davis V, Marks WJ, Ostrem JL, Simmons D, Lindsey N, Turner RS. Spontaneous pallidal neuronal activity in human dystonia: comparison with Parkinson's disease and normal macaque. J Neurophysiol. 2005 Jun; 93(6):3165-76.
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      44. Starr PA, Turner RS, Rau G, Lindsey N, Heath S, Volz M, Ostrem JL, Marks WJ. Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes. Neurosurg Focus. 2004 Jul 15; 17(1):E4.
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      45. Ostrem JL, Saver JL, Alger JR, Starkman S, Leary MC, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Gobin YP, Vinuela F, Kidwell CS. Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke. 2004 Feb; 35(2):e30-4.
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      46. Van Horn JD, Gold JM, Esposito G, Ostrem JL, Mattay V, Weinberger DR, Berman KF. Changing patterns of brain activation during maze learning. Brain Res. 1998 May 18; 793(1-2):29-38.
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      47. Goldberg TE, Berman KF, Fleming K, Ostrem J, Van Horn JD, Esposito G, Mattay VS, Gold JM, Weinberger DR. Uncoupling cognitive workload and prefrontal cortical physiology: a PET rCBF study. Neuroimage. 1998 May; 7(4 Pt 1):296-303.
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      48. Berman KF, Schmidt PJ, Rubinow DR, Danaceau MA, Van Horn JD, Esposito G, Ostrem JL, Weinberger DR. Modulation of cognition-specific cortical activity by gonadal steroids: a positron-emission tomography study in women. Proc Natl Acad Sci U S A. 1997 Aug 5; 94(16):8836-41.
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      49. Mattay VS, Berman KF, Ostrem JL, Esposito G, Van Horn JD, Bigelow LB, Weinberger DR. Dextroamphetamine enhances "neural network-specific" physiological signals: a positron-emission tomography rCBF study. J Neurosci. 1996 Aug 1; 16(15):4816-22.
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      50. Kirkby BS, Van Horn JD, Ostrem JL, Weinberger DR, Berman KF. Cognitive activation during PET: a case study of monozygotic twins discordant for closed head injury. Neuropsychologia. 1996 Jul; 34(7):689-97.
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      51. Berman KF, Ostrem JL, Randolph C, Gold J, Goldberg TE, Coppola R, Carson RE, Herscovitch P, Weinberger DR. Physiological activation of a cortical network during performance of the Wisconsin Card Sorting Test: a positron emission tomography study. Neuropsychologia. 1995 Aug; 33(8):1027-46.
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      52. Hyde TM, Nawroz S, Goldberg TE, Bigelow LB, Strong D, Ostrem JL, Weinberger DR, Kleinman JE. Is there cognitive decline in schizophrenia? A cross-sectional study. Br J Psychiatry. 1994 Apr; 164(4):494-500.
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      53. Rawleigh JM, Kemble ED, Ostrem J. Differential effects of prior dominance or subordination experience on conspecific odor preferences in mice. Physiol Behav. 1993 Jul; 54(1):35-9.
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      54. Ostrem JL, Rawleigh JM, Kemble ED. Effects of eltoprazine hydrochloride on reactivity to conspecific or novel odors and activity. Pharmacol Biochem Behav. 1992 Mar; 41(3):581-5.
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