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    Jirka Peschek, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentBiochemistry and Biophysics
    Address600 16th Street
    San Francisco CA 94158
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Nokwe CN, Hora M, Zacharias M, Yagi H, Peschek J, Reif B, Goto Y, Buchner J. A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions. J Mol Biol. 2016 Mar 27; 428(6):1315-32. PMID: 26827727.
        View in: PubMed
      2. Peschek J, Acosta-Alvear D, Mendez AS, Walter P. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. EMBO Rep. 2015 Dec; 16(12):1688-98. PMID: 26483401.
        View in: PubMed
      3. Mainz A, Peschek J, Stavropoulou M, Back KC, Bardiaux B, Asami S, Prade E, Peters C, Weinkauf S, Buchner J, Reif B. The chaperone aB-crystallin uses different interfaces to capture an amorphous and an amyloid client. Nat Struct Mol Biol. 2015 Nov; 22(11):898-905. PMID: 26458046.
        View in: PubMed
      4. Haslbeck M, Peschek J, Buchner J, Weinkauf S. Structure and function of a-crystallins: Traversing from in vitro to in vivo. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):149-66. PMID: 26116912.
        View in: PubMed
      5. Feige MJ, Gräwert MA, Marcinowski M, Hennig J, Behnke J, Ausländer D, Herold EM, Peschek J, Castro CD, Flajnik M, Hendershot LM, Sattler M, Groll M, Buchner J. The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22):8155-60. PMID: 24830426; PMCID: PMC4050542.
      6. Drazic A, Tsoutsoulopoulos A, Peschek J, Gundlach J, Krause M, Bach NC, Gebendorfer KM, Winter J. Role of cysteines in the stability and DNA-binding activity of the hypochlorite-specific transcription factor HypT. PLoS One. 2013; 8(10):e75683. PMID: 24116067; PMCID: PMC3792123.
      7. Peschek J, Braun N, Rohrberg J, Back KC, Kriehuber T, Kastenmüller A, Weinkauf S, Buchner J. Regulated structural transitions unleash the chaperone activity of aB-crystallin. Proc Natl Acad Sci U S A. 2013 Oct 1; 110(40):E3780-9. PMID: 24043785; PMCID: PMC3791731.
      8. Müller R, Gräwert MA, Kern T, Madl T, Peschek J, Sattler M, Groll M, Buchner J. High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10183-8. PMID: 23733956; PMCID: PMC3690842.
      9. Drazic A, Miura H, Peschek J, Le Y, Bach NC, Kriehuber T, Winter J. Methionine oxidation activates a transcription factor in response to oxidative stress. Proc Natl Acad Sci U S A. 2013 Jun 4; 110(23):9493-8. PMID: 23690622; PMCID: PMC3677443.
      10. Retzlaff M, Rohrberg J, Küpper NJ, Lagleder S, Bepperling A, Manzenrieder F, Peschek J, Kessler H, Buchner J. The regulatory domain stabilizes the p53 tetramer by intersubunit contacts with the DNA binding domain. J Mol Biol. 2013 Jan 9; 425(1):144-55. PMID: 23103206.
        View in: PubMed
      11. Braun N, Zacharias M, Peschek J, Kastenmüller A, Zou J, Hanzlik M, Haslbeck M, Rappsilber J, Buchner J, Weinkauf S. Multiple molecular architectures of the eye lens chaperone aB-crystallin elucidated by a triple hybrid approach. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20491-6. PMID: 22143763; PMCID: PMC3251151.
      12. Peschek J, Braun N, Franzmann TM, Georgalis Y, Haslbeck M, Weinkauf S, Buchner J. The eye lens chaperone alpha-crystallin forms defined globular assemblies. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13272-7. PMID: 19651604; PMCID: PMC2726422.
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