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    Joel Karliner, MD

    TitleProfessor Emeritus
    SchoolUCSF School of Medicine
    DepartmentMedicine
    Address550 16th Street
    San Francisco CA 94158
    Phone415-221-4810x3171
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoClinical Fellowship School of Medicine - Cardiology

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Goetzl EJ, Goetzl L, Karliner JS, Tang N, Pulliam L. Human plasma platelet-derived exosomes: effects of aspirin. FASEB J. 2016 May; 30(5):2058-63. PMID: 26873936.
        View in: PubMed
      2. Luk FS, Kim RY, Li K, Ching D, Wong DK, Joshi SK, Imhof I, Honbo N, Hoover H, Zhu BQ, Lovett DH, Karliner JS, Raffai RL. Immunosuppression With FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression That Survive Myocardial Infarction Caused by Coronary Atherosclerosis. J Cardiovasc Pharmacol. 2016 Jan; 67(1):47-56. PMID: 26322923.
        View in: PubMed
      3. Yeghiazarians Y, Honbo N, Imhof I, Woods B, Aguilera V, Ye J, Boyle AJ, Karliner JS. IL-15: a novel prosurvival signaling pathway in cardiomyocytes. J Cardiovasc Pharmacol. 2014 May; 63(5):406-11. PMID: 24805144; PMCID: PMC4115639.
      4. Karliner JS. Arsonists and firefighters: the perpetual inflammatory civil war for survival. Circulation. 2014 Jun 10; 129(23):2368-70. PMID: 24710031; PMCID: PMC4061904.
      5. Karliner JS. Selected aspects of cellular responses in heart failure. J Cardiovasc Pharmacol. 2014 Feb; 63(2):83-4. PMID: 24390177.
        View in: PubMed
      6. Wang G, Kim RY, Imhof I, Honbo N, Luk FS, Li K, Kumar N, Zhu BQ, Eberlé D, Ching D, Karliner JS, Raffai RL. The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction. J Cardiovasc Pharmacol. 2014 Feb; 63(2):132-43. PMID: 24508946; PMCID: PMC4574629.
      7. Lovett DH, Mahimkar R, Raffai RL, Cape L, Zhu BQ, Jin ZQ, Baker AJ, Karliner JS. N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure. PLoS One. 2013; 8(7):e68154. PMID: 23874529; PMCID: PMC3712965.
      8. Kawabori M, Kacimi R, Karliner JS, Yenari MA. Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets. World J Cardiol. 2013 Apr 26; 5(4):75-86. PMID: 23675553; PMCID: PMC3653015.
      9. Vessey DA, Li L, Imhof I, Honbo N, Karliner JS. FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning. Med Sci Monit Basic Res. 2013; 19:126-32. PMID: 23567658; PMCID: PMC3659128.
      10. Karliner JS. Sphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progress. Biochim Biophys Acta. 2013 Jan; 1831(1):203-12. PMID: 22735359; PMCID: PMC3479372.
      11. Lovett DH, Mahimkar R, Raffai RL, Cape L, Maklashina E, Cecchini G, Karliner JS. A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity. PLoS One. 2012; 7(4):e34177. PMID: 22509276; PMCID: PMC3317925.
      12. Bauerly K, Harris C, Chowanadisai W, Graham J, Havel PJ, Tchaparian E, Satre M, Karliner JS, Rucker RB. Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. PLoS One. 2011; 6(7):e21779. PMID: 21814553; PMCID: PMC3140972.
      13. Vessey DA, Li L, Jin ZQ, Kelley M, Honbo N, Zhang J, Karliner JS. A sphingosine kinase form 2 knockout sensitizes mouse myocardium to ischemia/reoxygenation injury and diminishes responsiveness to ischemic preconditioning. Oxid Med Cell Longev. 2011; 2011:961059. PMID: 21904650; PMCID: PMC3166792.
      14. Bandhuvula P, Honbo N, Wang GY, Jin ZQ, Fyrst H, Zhang M, Borowsky AD, Dillard L, Karliner JS, Saba JD. S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart. Am J Physiol Heart Circ Physiol. 2011 May; 300(5):H1753-61. PMID: 21335477; PMCID: PMC3094087.
      15. Tao R, Kim SH, Honbo N, Karliner JS, Alano CC. Minocycline protects cardiac myocytes against simulated ischemia–reperfusion injury by inhibiting poly(ADP-ribose) polymerase-1. J Cardiovasc Pharmacol. 2010 Dec; 56(6):659-68. PMID: 20881608; PMCID: PMC3064957.
      16. Dahi S, Karliner JS, Sarkar R, Lovett DH. Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia. Int J Exp Pathol. 2011 Feb; 92(1):50-6. PMID: 21039989; PMCID: PMC3052756.
      17. Zhang J, Chatterjee K, Alano CC, Kalinowski MA, Honbo N, Karliner JS. Vincristine attenuates N-methyl-N'-nitro-N-nitrosoguanidine-induced poly-(ADP) ribose polymerase activity in cardiomyocytes. J Cardiovasc Pharmacol. 2010 Mar; 55(3):219-26. PMID: 20375713; PMCID: PMC2865187.
      18. Tao R, Hoover HE, Honbo N, Kalinowski M, Alano CC, Karliner JS, Raffai R. High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate. Am J Physiol Heart Circ Physiol. 2010 Mar; 298(3):H1022-8. PMID: 20061542; PMCID: PMC2838562.
      19. Kotlyar AB, Randazzo A, Honbo N, Jin ZQ, Karliner JS, Cecchini G. Cardioprotective activity of a novel and potent competitive inhibitor of lactate dehydrogenase. FEBS Lett. 2010 Jan 4; 584(1):159-65. PMID: 19913538; PMCID: PMC2794998.
      20. Chatterjee K, Zhang J, Honbo N, Karliner JS. Doxorubicin cardiomyopathy. Cardiology. 2010; 115(2):155-62. PMID: 20016174; PMCID: PMC2848530.
      21. Karliner JS. Lessons from the besotted heart. J Am Coll Cardiol. 2009 Dec 1; 54(23):2197-8. PMID: 19942092.
        View in: PubMed
      22. Vessey DA, Li L, Honbo N, Karliner JS. Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning. Am J Physiol Heart Circ Physiol. 2009 Oct; 297(4):H1429-35. PMID: 19648253; PMCID: PMC2770755.
      23. Tao R, Hoover HE, Zhang J, Honbo N, Alano CC, Karliner JS. Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitization. J Cardiovasc Pharmacol. 2009 Jun; 53(6):486-94. PMID: 19433984; PMCID: PMC2835551.
      24. Li H, Malhotra D, Yeh CC, Tu R, Zhu BQ, Birger N, Wisneski A, Cha J, Karliner JS, Mann MJ. Myocardial survival signaling in response to stem cell transplantation. J Am Coll Surg. 2009 Apr; 208(4):607-13. PMID: 19476797; PMCID: PMC2817986.
      25. Karliner JS, Brown JH. Lipid signalling in cardiovascular pathophysiology. Cardiovasc Res. 2009 May 1; 82(2):171-4. PMID: 19297369.
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      26. Karliner JS. Sphingosine kinase and sphingosine 1-phosphate in cardioprotection. J Cardiovasc Pharmacol. 2009 Mar; 53(3):189-97. PMID: 19247197; PMCID: PMC2835544.
      27. Yeh CC, Li H, Malhotra D, Huang MC, Zhu BQ, Goetzl EJ, Vessey DA, Karliner JS, Mann MJ. Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H1193-9. PMID: 19234089; PMCID: PMC2670694.
      28. Karliner JS. Sphingosine kinase regulation and cardioprotection. Cardiovasc Res. 2009 May 1; 82(2):184-92. PMID: 19017750; PMCID: PMC2721648.
      29. Mahimkar R, Nguyen A, Mann M, Yeh CC, Zhu BQ, Karliner JS, Lovett DH. Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease. Cardiovasc Pathol. 2009 Sep-Oct; 18(5):253-61. PMID: 18835790; PMCID: PMC3367668.
      30. Vessey DA, Li L, Kelley M, Karliner JS. Combined sphingosine, S1P and ischemic postconditioning rescue the heart after protracted ischemia. Biochem Biophys Res Commun. 2008 Oct 24; 375(3):425-9. PMID: 18706887; PMCID: PMC3402379.
      31. Chatterjee K, Zhang J, Tao R, Honbo N, Karliner JS. Vincristine attenuates doxorubicin cardiotoxicity. Biochem Biophys Res Commun. 2008 Sep 5; 373(4):555-60. PMID: 18590705; PMCID: PMC2846088.
      32. Jin ZQ, Karliner JS, Vessey DA. Ischaemic postconditioning protects isolated mouse hearts against ischaemia/reperfusion injury via sphingosine kinase isoform-1 activation. Cardiovasc Res. 2008 Jul 1; 79(1):134-40. PMID: 18334546.
        View in: PubMed
      33. Vessey DA, Li L, Kelley M, Zhang J, Karliner JS. Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate. J Biochem Mol Toxicol. 2008 Mar-Apr; 22(2):113-8. PMID: 18418901.
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      34. Alano CC, Tran A, Tao R, Ying W, Karliner JS, Swanson RA. Differences among cell types in NAD(+) compartmentalization: a comparison of neurons, astrocytes, and cardiac myocytes. J Neurosci Res. 2007 Nov 15; 85(15):3378-85. PMID: 17853438.
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      35. McCloskey DT, Turcato S, Wang GY, Turnbull L, Zhu BQ, Bambino T, Nguyen AP, Lovett DH, Nissenson RA, Karliner JS, Baker AJ. Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H205-12. PMID: 17965283; PMCID: PMC3372085.
      36. Grivennikova VG, Kotlyar AB, Karliner JS, Cecchini G, Vinogradov AD. Redox-dependent change of nucleotide affinity to the active site of the mammalian complex I. Biochemistry. 2007 Sep 25; 46(38):10971-8. PMID: 17760425; PMCID: PMC2258335.
      37. Zhang J, Honbo N, Goetzl EJ, Chatterjee K, Karliner JS, Gray MO. Signals from type 1 sphingosine 1-phosphate receptors enhance adult mouse cardiac myocyte survival during hypoxia. Am J Physiol Heart Circ Physiol. 2007 Nov; 293(5):H3150-8. PMID: 17766476.
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      38. Tao R, Karliner JS, Simonis U, Zheng J, Zhang J, Honbo N, Alano CC. Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes. Biochem Biophys Res Commun. 2007 Nov 16; 363(2):257-62. PMID: 17880922; PMCID: PMC2844438.
      39. Bao X, Lu CM, Liu F, Gu Y, Dalton ND, Zhu BQ, Foster E, Chen J, Karliner JS, Ross J, Simpson PC, Ziegler MG. Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse. Circulation. 2007 Aug 28; 116(9):1024-31. PMID: 17698731.
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      40. Chatterjee K, Zhang J, Honbo N, Simonis U, Shaw R, Karliner JS. Acute vincristine pretreatment protects adult mouse cardiac myocytes from oxidative stress. J Mol Cell Cardiol. 2007 Sep; 43(3):327-36. PMID: 17662302.
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      41. Jin ZQ, Zhang J, Huang Y, Hoover HE, Vessey DA, Karliner JS. A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. Cardiovasc Res. 2007 Oct 1; 76(1):41-50. PMID: 17610857.
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      42. Zhou HZ, Ma X, Gray MO, Zhu BQ, Nguyen AP, Baker AJ, Simonis U, Cecchini G, Lovett DH, Karliner JS. Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction. Biochem Biophys Res Commun. 2007 Jun 22; 358(1):189-95. PMID: 17475219; PMCID: PMC3423089.
      43. Kacimi R, Vessey DA, Honbo N, Karliner JS. Adult cardiac fibroblasts null for sphingosine kinase-1 exhibit growth dysregulation and an enhanced proinflammatory response. J Mol Cell Cardiol. 2007 Jul; 43(1):85-91. PMID: 17512943.
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      44. Tao R, Zhang J, Vessey DA, Honbo N, Karliner JS. Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes. Cardiovasc Res. 2007 Apr 1; 74(1):56-63. PMID: 17320845.
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      45. Vessey DA, Kelley M, Zhang J, Li L, Tao R, Karliner JS. Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart. J Biochem Mol Toxicol. 2007; 21(5):273-9. PMID: 17912702.
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      46. Bergman MR, Teerlink JR, Mahimkar R, Li L, Zhu BQ, Nguyen A, Dahi S, Karliner JS, Lovett DH. Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am J Physiol Heart Circ Physiol. 2007 Apr; 292(4):H1847-60. PMID: 17158653.
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      47. Vessey DA, Kelley M, Li L, Huang Y, Zhou HZ, Zhu BQ, Karliner JS. Role of sphingosine kinase activity in protection of heart against ischemia reperfusion injury. Med Sci Monit. 2006 Oct; 12(10):BR318-24. PMID: 17006394.
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      48. Karliner JS. Toward solving the riddle: the enigma becomes less mysterious. Circ Res. 2006 Sep 1; 99(5):465-7. PMID: 16946142.
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      49. Jin ZQ, Karliner JS. Low dose N, N-dimethylsphingosine is cardioprotective and activates cytosolic sphingosine kinase by a PKCepsilon dependent mechanism. Cardiovasc Res. 2006 Sep 1; 71(4):725-34. PMID: 16831409.
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      50. Zhu BQ, Simonis U, Cecchini G, Zhou HZ, Li L, Teerlink JR, Karliner JS. Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther. 2006 Jun; 11(2):119-28. PMID: 16891289.
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      51. Alfonso-Jaume MA, Bergman MR, Mahimkar R, Cheng S, Jin ZQ, Karliner JS, Lovett DH. Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB. Am J Physiol Heart Circ Physiol. 2006 Oct; 291(4):H1838-46. PMID: 16699069.
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      52. Turcato S, Turnbull L, Wang GY, Honbo N, Simpson PC, Karliner JS, Baker AJ. Ischemic preconditioning depends on age and gender. Basic Res Cardiol. 2006 May; 101(3):235-43. PMID: 16450074.
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      53. Turnbull L, Zhou HZ, Swigart PM, Turcato S, Karliner JS, Conklin BR, Simpson PC, Baker AJ. Sustained preconditioning induced by cardiac transgenesis with the tetracycline transactivator. Am J Physiol Heart Circ Physiol. 2006 Mar; 290(3):H1103-9. PMID: 16243914.
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      54. Wang GY, Bergman MR, Nguyen AP, Turcato S, Swigart PM, Rodrigo MC, Simpson PC, Karliner JS, Lovett DH, Baker AJ. Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility. Cardiovasc Res. 2006 Feb 15; 69(3):688-96. PMID: 16183043.
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      55. Kotlyar AB, Karliner JS, Cecchini G. A novel strong competitive inhibitor of complex I. FEBS Lett. 2005 Aug 29; 579(21):4861-6. PMID: 16107251.
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      56. Karliner JS. Off the shelf but not mass produced. Chem Biol. 2005 Jun; 12(6):614-5. PMID: 15975506.
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      57. Karliner JS. Symbols within words: have we neglected the AdeNOsine A2 receptor? Cardiovasc Res. 2005 Mar 1; 65(4):763-5. PMID: 15721853.
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      58. Vessey DA, Kelley M, Karliner JS. A rapid radioassay for sphingosine kinase. Anal Biochem. 2005 Feb 1; 337(1):136-42. PMID: 15649386.
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      59. Jin ZQ, Zhou HZ, Cecchini G, Gray MO, Karliner JS. MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2986-94. PMID: 15681709.
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      60. Zhu BQ, Zhou HZ, Teerlink JR, Karliner JS. Pyrroloquinoline quinone (PQQ) decreases myocardial infarct size and improves cardiac function in rat models of ischemia and ischemia/reperfusion. Cardiovasc Drugs Ther. 2004 Nov; 18(6):421-31. PMID: 15770429.
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      61. Jin ZQ, Goetzl EJ, Karliner JS. Sphingosine kinase activation mediates ischemic preconditioning in murine heart. Circulation. 2004 Oct 5; 110(14):1980-9. PMID: 15451787.
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      62. Karliner JS. Mechanisms of cardioprotection by lysophospholipids. J Cell Biochem. 2004 Aug 15; 92(6):1095-103. PMID: 15258895.
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      63. Chi NC, Karliner JS. Molecular determinants of responses to myocardial ischemia/reperfusion injury: focus on hypoxia-inducible and heat shock factors. Cardiovasc Res. 2004 Feb 15; 61(3):437-47. PMID: 14962475.
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      64. Maklashina E, Kotlyar AB, Karliner JS, Cecchini G. Effect of oxygen on activation state of complex I and lack of oxaloacetate inhibition of complex II in Langendorff perfused rat heart. FEBS Lett. 2004 Jan 2; 556(1-3):64-8. PMID: 14706827.
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      65. Zhu BQ, Heeschen C, Sievers RE, Karliner JS, Parmley WW, Glantz SA, Cooke JP. Second hand smoke stimulates tumor angiogenesis and growth. Cancer Cell. 2003 Sep; 4(3):191-6. PMID: 14522253.
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      66. Graeler MH, Kong Y, Karliner JS, Goetzl EJ. Protein kinase C epsilon dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes. J Biol Chem. 2003 Jul 25; 278(30):27737-41. PMID: 12782628.
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      67. Zhu BQ, Sievers RE, Browne AE, Lee RJ, Chatterjee K, Grossman W, Karliner JS, Parmley WW. Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function. J Renin Angiotensin Aldosterone Syst. 2003 Mar; 4(1):31-7. PMID: 12692751.
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      68. Bergman MR, Cheng S, Honbo N, Piacentini L, Karliner JS, Lovett DH. A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers. Biochem J. 2003 Feb 1; 369(Pt 3):485-96. PMID: 12371906; PMCID: PMC1223099.
      69. Maklashina E, Sher Y, Zhou HZ, Gray MO, Karliner JS, Cecchini G. Effect of anoxia/reperfusion on the reversible active/de-active transition of NADH-ubiquinone oxidoreductase (complex I) in rat heart. Biochim Biophys Acta. 2002 Oct 3; 1556(1):6-12. PMID: 12351213.
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      70. Zhou HZ, Karliner JS, Gray MO. Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt. Am J Physiol Heart Circ Physiol. 2002 Jul; 283(1):H165-74. PMID: 12063287.
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      71. Jin ZQ, Zhou HZ, Zhu P, Honbo N, Mochly-Rosen D, Messing RO, Goetzl EJ, Karliner JS, Gray MO. Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts. Am J Physiol Heart Circ Physiol. 2002 Jun; 282(6):H1970-7. PMID: 12003800.
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      72. Karliner JS. Lysophospholipids and the cardiovascular system. Biochim Biophys Acta. 2002 May 23; 1582(1-3):216-21. PMID: 12069831.
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      73. Karliner JS, Honbo N, Summers K, Gray MO, Goetzl EJ. The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes. J Mol Cell Cardiol. 2001 Sep; 33(9):1713-7. PMID: 11549349.
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      74. Karliner JS, Honbo N, Epstein CJ, Xian M, Lau YF, Gray MO. Neonatal mouse cardiac myocytes exhibit cardioprotection induced by hypoxic and pharmacologic preconditioning and by transgenic overexpression of human Cu/Zn superoxide dismutase. J Mol Cell Cardiol. 2000 Oct; 32(10):1779-86. PMID: 11013122.
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      75. Goetzl EJ, Lee H, Azuma T, Stossel TP, Turck CW, Karliner JS. Gelsolin binding and cellular presentation of lysophosphatidic acid. J Biol Chem. 2000 May 12; 275(19):14573-8. PMID: 10799543.
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      76. Kacimi R, Chentoufi J, Honbo N, Long CS, Karliner JS. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection. Cardiovasc Res. 2000 Apr; 46(1):139-50. PMID: 10727662.
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      77. Piacentini L, Gray M, Honbo NY, Chentoufi J, Bergman M, Karliner JS. Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C. J Mol Cell Cardiol. 2000 Apr; 32(4):565-76. PMID: 10756114.
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      78. Goetzl EJ, Lee H, Dolezalova H, Kalli KR, Conover CA, Hu YL, Azuma T, Stossel TP, Karliner JS, Jaffe RB. Mechanisms of lysolipid phosphate effects on cellular survival and proliferation. Ann N Y Acad Sci. 2000 Apr; 905:177-87. PMID: 10818453.
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      79. Xian M, Honbo N, Zhang J, Liew CC, Karliner JS, Lau YF. The green fluorescent protein is an efficient biological marker for cardiac myocytes. J Mol Cell Cardiol. 1999 Dec; 31(12):2155-65. PMID: 10640443.
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      80. Piacentini L, Karliner JS. Altered gene expression during hypoxia and reoxygenation of the heart. Pharmacol Ther. 1999 Jul; 83(1):21-37. PMID: 10501593.
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      81. Karliner J, Srivastava A, Bruno K. United Nations Development Program solicits funds from corporations. Int J Health Serv. 1999; 29(4):813-9. PMID: 10615575.
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      82. Gray MO, Long CS, Kalinyak JE, Li HT, Karliner JS. Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblasts. Cardiovasc Res. 1998 Nov; 40(2):352-63. PMID: 9893729.
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      83. Kacimi R, Karliner JS, Koudssi F, Long CS. Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia. Circ Res. 1998 Mar 23; 82(5):576-86. PMID: 9529162.
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      84. Gray MO, Karliner JS, Mochly-Rosen D. A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. J Biol Chem. 1997 Dec 5; 272(49):30945-51. PMID: 9388241.
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      85. Kacimi R, Long CS, Karliner JS. Chronic hypoxia modulates the interleukin-1beta-stimulated inducible nitric oxide synthase pathway in cardiac myocytes. Circulation. 1997 Sep 16; 96(6):1937-43. PMID: 9323084.
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      86. Li HT, Long CS, Gray MO, Rokosh DG, Honbo NY, Karliner JS. Cross talk between angiotensin AT1 and alpha 1-adrenergic receptors: angiotensin II downregulates alpha 1a-adrenergic receptor subtype mRNA and density in neonatal rat cardiac myocytes. Circ Res. 1997 Sep; 81(3):396-403. PMID: 9285642.
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      87. Li HT, Honbo NY, Karliner JS. Chronic hypoxia increases beta 1-adrenergic receptor mRNA and density but not signaling in neonatal rat cardiac myocytes. Circulation. 1996 Dec 15; 94(12):3303-10. PMID: 8989144.
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      88. Johnson JA, Gray MO, Karliner JS, Chen CH, Mochly-Rosen D. An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research. Circ Res. 1996 Dec; 79(6):1086-99. PMID: 8943947.
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      89. Rokosh DG, Stewart AF, Chang KC, Bailey BA, Karliner JS, Camacho SA, Long CS, Simpson PC. Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C. J Biol Chem. 1996 Mar 8; 271(10):5839-43. PMID: 8621454.
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      90. Li HT, Long CS, Rokosh DG, Honbo NY, Karliner JS. Chronic hypoxia differentially regulates alpha 1-adrenergic receptor subtype mRNAs and inhibits alpha 1-adrenergic receptor-stimulated cardiac hypertrophy and signaling. Circulation. 1995 Aug 15; 92(4):918-25. PMID: 7641375.
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      91. Rocha-Singh KJ, Matsuo R, Karliner JS. Prolonged incubation with neuropeptide Y upregulates beta-adrenoceptors yet does not cause supersensitivity of beta-adrenoceptor signaling. Eur J Pharmacol. 1995 Feb 15; 288(3):349-53. PMID: 7774679.
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      92. Wolff AA, Hines DK, Karliner JS. Preserved beta-adrenoceptor-mediated adenylyl cyclase activity despite receptor and postreceptor dysfunction in acute myocardial ischemia. Am Heart J. 1994 Sep; 128(3):542-50. PMID: 8074018.
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      93. Paraschos A, Karliner JS. Receptor crosstalk: effects of prolonged carbachol exposure on beta 1-adrenoceptors and adenylyl cyclase activity in neonatal rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 1994 Sep; 350(3):267-76. PMID: 7824043.
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      94. Reupcke C, Paraschos A, Honbo N, Karliner JS. A phorbol ester augments cAMP content and adenylyl cyclase activity in neonatal rat cardiac myocytes despite reduced beta adrenoceptor density. Cardiovasc Res. 1993 Dec; 27(12):2179-85. PMID: 8313426.
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      95. Barrett S, Honbo N, Karliner JS. Alpha 1-adrenoceptor-mediated inhibition of cellular cAMP accumulation in neonatal rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 1993 Apr; 347(4):384-93. PMID: 7685501.
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      96. Narahara KA, Singh BN, Karliner JS, Corday SR, Hossack KF. Bepridil hydrochloride compared with placebo in patients with stable angina pectoris. Am J Cardiol. 1992 Apr 9; 69(11):37D-42D. PMID: 1553890.
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      97. Rocha-Singh KJ, Hines DK, Honbo NY, Karliner JS. Concanavalin A amplifies both beta-adrenergic and muscarinic cholinergic receptor-adenylate cyclase-linked pathways in cardiac myocytes. J Clin Invest. 1991 Sep; 88(3):760-6. PMID: 1653274; PMCID: PMC295459.
      98. Rocha-Singh KJ, Honbo NY, Karliner JS. Hypoxia and glucose independently regulate the beta-adrenergic receptor-adenylate cyclase system in cardiac myocytes. J Clin Invest. 1991 Jul; 88(1):204-13. PMID: 1647415; PMCID: PMC296021.
      99. Kagiya T, Rocha-Singh KJ, Honbo N, Karliner JS. Alpha 1 adrenoceptor mediated signal transduction in neonatal rat ventricular myocytes: effects of prolonged hypoxia and reoxygenation. Cardiovasc Res. 1991 Jul; 25(7):609-16. PMID: 1655268.
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      100. Simpson PC, Kariya K, Karns LR, Long CS, Karliner JS. Adrenergic hormones and control of cardiac myocyte growth. Mol Cell Biochem. 1991 May 29-Jun 12; 104(1-2):35-43. PMID: 1656195.
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      101. Karliner JS. Right bundle branch block after anterior myocardial infarction. J Am Coll Cardiol. 1991 Mar 15; 17(4):864-5. PMID: 1999621.
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      102. Keung EC, Karliner JS. Complex regulation of calcium current in cardiac cells. Dependence on a pertussis toxin-sensitive substrate, adenosine triphosphate, and an alpha 1-adrenoceptor. J Clin Invest. 1990 Mar; 85(3):950-4. PMID: 1968910; PMCID: PMC296515.
      103. Karliner JS, Kagiya T, Simpson PC. Effects of pertussis toxin on alpha 1-agonist-mediated phosphatidylinositide turnover and myocardial cell hypertrophy in neonatal rat ventricular myocytes. Experientia. 1990 Jan 15; 46(1):81-4. PMID: 2153573.
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      104. Wolff AA, Hines DK, Karliner JS. Refined membrane preparations mask ischemic fall in myocardial beta-receptor density. Am J Physiol. 1989 Sep; 257(3 Pt 2):H1032-6. PMID: 2551189.
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      105. Karliner JS, Stevens MB, Honbo N, Hoffman JI. Effects of acute ischemia in the dog on myocardial blood flow, beta receptors, and adenylate cyclase activity with and without chronic beta blockade. J Clin Invest. 1989 Feb; 83(2):474-81. PMID: 2563265; PMCID: PMC303703.
      106. Karliner JS. Effects of beta-blockade on beta-adrenergic receptors and signal transduction. J Cardiovasc Pharmacol. 1989; 14 Suppl 5:S6-12. PMID: 2478812.
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      107. Karliner JS, Scheinman M. Adenylate cyclase activity coupled to the stimulatory guanine nucleotide binding protein in patients having electrophysiologic studies and either structurally normal hearts or idiopathic myocardial disease. Am J Cardiol. 1988 Nov 15; 62(16):1129-30. PMID: 3142244.
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      108. Karliner JS, Simpson PC. Beta-adrenoceptor and adenylate cyclase regulation in cardiac myocyte growth. Basic Res Cardiol. 1988 Nov-Dec; 83(6):655-63. PMID: 2851972.
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      109. Vandenbossche JL, Massie BM, Schiller NB, Karliner JS. Relation of left ventricular shape to volume and mass in patients with minimally symptomatic chronic aortic regurgitation. Am Heart J. 1988 Oct; 116(4):1022-7. PMID: 2972178.
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      110. Vandenbossche JL, Taylor JE, Karliner JS. Left ventricular functional recovery from exercise in normals and patients with coronary heart disease. Cardiology. 1987; 74(2):111-5. PMID: 3568049.
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      111. Simpson P, Bishopric N, Coughlin S, Karliner J, Ordahl C, Starksen N, Tsao T, White N, Williams L. Dual trophic effects of the alpha 1-adrenergic receptor in cultured neonatal rat heart muscle cells. J Mol Cell Cardiol. 1986 Nov; 18 Suppl 5:45-58. PMID: 3027351.
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      112. Karliner JS, Stevens M, Grattan M, Woloszyn W, Honbo N, Hoffman JI. Beta-adrenergic receptor properties of canine myocardium: effects of chronic myocardial infarction. J Am Coll Cardiol. 1986 Aug; 8(2):349-56. PMID: 3016063.
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      113. Srebro J, Karliner JS. Congestive heart failure. Curr Probl Cardiol. 1986 Jun; 11(6):301-65. PMID: 2872998.
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      114. Karliner JS, Simpson PC, Honbo N, Woloszyn W. Mechanisms and time course of beta 1 adrenoceptor desensitisation in mammalian cardiac myocytes. Cardiovasc Res. 1986 Mar; 20(3):221-8. PMID: 3011269.
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      115. Karliner JS. Left ventricular mechanical efficiency in coronary artery disease. J Am Coll Cardiol. 1986 Feb; 7(2):282-3. PMID: 3944345.
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      116. Karliner JS. Combination therapy for angina pectoris. J Am Coll Cardiol. 1986 Feb; 7(2):336-7. PMID: 2868031.
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      117. Karliner JS, Simpson PC, Taylor JE, Honbo N, Woloszyn W. Adrenergic receptor characteristics of cardiac myocytes cultured in serum-free medium: comparison with serum-supplemented medium. Biochem Biophys Res Commun. 1985 Apr 16; 128(1):376-82. PMID: 3985976.
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      118. Karliner JS, Sarnquist FF, Graber DJ, Peters RM, West JB. The electrocardiogram at extreme altitude: experience on Mt. Everest. Am Heart J. 1985 Mar; 109(3 Pt 1):505-13. PMID: 3976477.
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      119. Vandenbossche JL, Kramer BL, Massie BM, Morris DL, Karliner JS. Two-dimensional echocardiographic evaluation of the size, function and shape of the left ventricle in chronic aortic regurgitation: comparison with radionuclide angiography. J Am Coll Cardiol. 1984 Dec; 4(6):1195-206. PMID: 6094638.
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      120. Mancini GB, Costello D, Bhargava V, Lew W, LeWinter M, Karliner JS. The isovolumic index: a new noninvasive approach to the assessment of left ventricular function in man. Am J Cardiol. 1982 Dec; 50(6):1401-8. PMID: 7148720.
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      121. Kreitenberg A, Karliner JS, Engler RL, Marchand ER. A simple teaching device for examination of the arterial and venous pulse. Am J Cardiol. 1982 Dec; 50(6):1391-3. PMID: 7148719.
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      122. Watkins J, Slutsky R, Tubau J, Karliner J. Scintigraphic study of relation between left ventricular peak systolic pressure and end-systolic volume in patients with coronary artery disease and normal subjects. Br Heart J. 1982 Jul; 48(1):39-47. PMID: 7082512; PMCID: PMC481200.
      123. Karliner JS, Motulsky HJ, Dunlap J, Brown JH, Insel PA. Verapamil competitively inhibits alpha 1-adrenergic and muscarinic but not beta-adrenergic receptors in rat myocardium. J Cardiovasc Pharmacol. 1982 May-Jun; 4(3):515-20. PMID: 6177951.
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      124. Karliner JS, Motulsky HJ, Insel PA. Apparent "down-regulation" of human platelet alpha 2-adrenergic receptors is due to retained agonist. Mol Pharmacol. 1982 Jan; 21(1):36-43. PMID: 6127620.
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      125. Barnes PJ, Karliner JS. In vivo identification and distribution of alpha- and beta-adrenoceptors in rat heart and lung. Pharmacology. 1982; 24(6):321-7. PMID: 6287506.
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      126. Karliner JS. Assessment of isovolumic and ejection phase indices of left ventricular performance. Herz. 1981 Aug; 6(4):195-208. PMID: 6455373.
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      127. Karliner JS, Alabaster C, Stephens H, Barnes P, Dollery C. Enhanced noradrenaline response in cardiomyopathic hamsters: possible relation to changes in adrenoceptors studied by radioligand binding. Cardiovasc Res. 1981 May; 15(5):296-304. PMID: 7296587.
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      128. Slutsky R, Hooper W, Ackerman W, Ashburn W, Gerber K, Moser K, Karliner J. Evaluation of left ventricular function in chronic pulmonary disease by exercise gated equilibrium radionuclide angiography. Am Heart J. 1981 Apr; 101(4):414-20. PMID: 7211669.
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      129. Slutsky R, Watkins J, Peterson K, Karliner J. The response of left ventricular function and size to atrial pacing, volume loading and afterload stress in patients with coronary artery disease. Circulation. 1981 Apr; 63(4):864-70. PMID: 7471343.
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      130. Ryan W, Karliner JS, Gilpin EA, Covell JW, DeLuca M, Ross J. The creatine kinase curve area and peak creatine kinase after acute myocardial infarction: usefulness and limitations. Am Heart J. 1981 Feb; 101(2):162-8. PMID: 7468417.
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      131. Slutsky R, Karliner J, Gerber K, Battler A, Froelicher V, Gregoratos G, Peterson K, Ashburn W. Peak systolic blood pressure/end-systolic volume ratio: assessment at rest and during exercise in normal subjects and patients with coronary heart disease. Am J Cardiol. 1980 Nov; 46(5):813-20. PMID: 7435392.
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      132. Karliner JS, Barnes P, Brown M, Dollery C. Chronic heart failure in the guinea pig increases cardiac alpha 1- and beta-adrenoceptors. Eur J Pharmacol. 1980 Oct 3; 67(1):115-8. PMID: 6252020.
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      133. Slutsky R, Karliner JS, Battler A, Peterson K, Ross J. Comparison of early systolic and holosystolic ejection phase indexes by contrast ventriculography in patients with coronary artery disease. Circulation. 1980 Jun; 61(6):1083-90. PMID: 7371121.
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      134. Barnes PJ, Karliner JS, Dollery CT. Human lung adrenoreceptors studied by radioligand binding. Clin Sci (Lond). 1980 Jun; 58(6):457-61. PMID: 6253116.
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      135. Battler A, Karliner JS, Higgins CB, Slutsky R, Gilpin EA, Froelicher VF, Ross J. The initial chest x-ray in acute myocardial infarction. Prediction of early and late mortality and survival. Circulation. 1980 May; 61(5):1004-9. PMID: 6444853.
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      136. LeWinter MM, Engler RL, Karliner JS. Tocainide therapy for treatment of ventricular arrhythmias: assessment with ambulatory electrocardiographic monitoring and treadmill exercise. Am J Cardiol. 1980 May; 45(5):1045-52. PMID: 6768281.
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      137. Slutsky R, Battler A, Gerber K, Gordon D, Froelicher V, Karliner J, Ashburn W. Effect of nitrates on left ventricular size and function during exercise: comparison of sublingual nitroglycerin and nitroglycerin paste. Am J Cardiol. 1980 Apr; 45(4):831-40. PMID: 6767386.
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      138. Battler A, Slutsky R, Karliner J, Froelicher V, Ashburn W, Ross J. Left ventricular ejection fraction and first third ejection fraction early after acute myocardial infarction: value for predicting mortality and morbidity. Am J Cardiol. 1980 Feb; 45(2):197-202. PMID: 7355729.
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      139. Slutsky RA, Ackerman W, Karliner JS, Ashburn WL, Moser KM. Right and left ventricular dysfunction in patients with chronic obstructive lung disease. Assessment by first-pass radionuclide angiography. Am J Med. 1980 Feb; 68(2):197-205. PMID: 7355891.
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      140. LeWinter MM, Engler RL, Karliner JS. Enhanced left ventricular shortening during chronic volume overload in conscious dogs. Am J Physiol. 1980 Feb; 238(2):H126-33. PMID: 7361905.
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      141. Slutsky R, Hooper W, Gerber K, Battler A, Froelicher V, Ashburn W, Karliner J. Assessment of right ventricular function at rest and during exercise in patients with coronary heart disease: a new approach using equilibrium radionuclide angiography. Am J Cardiol. 1980 Jan; 45(1):63-71. PMID: 7350775.
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      142. Barnes PJ, Dollery CT, Hamilton CA, Karliner JS. Alpha-adrenoceptor binding in guinea-pig lung using [3H]-prazosin [proceedings]. Br J Pharmacol. 1980 Jan; 68(1):138P. PMID: 6244025; PMCID: PMC2044134.
      143. Ryan WF, Henning H, Karliner JS. Effects of morphine on left ventricular dimensions and function in patients with previous myocardial infarction. Clin Cardiol. 1979 Dec; 2(6):417-23. PMID: 544111.
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      144. Slutsky R, Curtis G, Battler A, Froelicher V, Ross J, Gordon D, Ashburn W, Karliner J. Effect of sublingual nitroglycerin on left ventricular function at rest and during spontaneous angina pectoris: assessment with a radionuclide approach. Am J Cardiol. 1979 Dec; 44(7):1365-70. PMID: 116534.
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      145. Kumada T, Karliner JS, Pouleur H, Gallagher KP, Shirato K, Ross J. Effects of coronary occlusion on early ventricular diastolic events in conscious dogs. Am J Physiol. 1979 Nov; 237(5):H542-9. PMID: 495759.
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      146. Engler RL, Le Winter MM, Karliner JS. Depressant effects of quinidine gluconate on left ventricular function in conscious dogs with and without volume overload. Circulation. 1979 Oct; 60(4):828-35. PMID: 476888.
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      147. Barnes P, Karliner J, Hamilton C, Dollery C. Demonstration of alpha 1-adrenoceptors in guinea pig lung using 3H-prazosin. Life Sci. 1979 Oct 1; 25(14):1207-14. PMID: 229373.
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      148. Karliner JS, Barnes P, Hamilton CA, Dollery CT. alpha 1-Adrenergic receptors in guinea pig myocardium: identification by binding of a new radioligand, (3H)-prazosin. Biochem Biophys Res Commun. 1979 Sep 12; 90(1):142-9. PMID: 227385.
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      149. Slutsky R, Karliner J, Ricci D, Schuler G, Pfisterer M, Peterson K, Ashburn W. Response of left ventricular volume to exercise in man assessed by radionuclide equilibrium angiography. Circulation. 1979 Sep; 60(3):565-71. PMID: 455619.
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      150. Slutsky R, Karliner J, Ricci D, Kaiser R, Pfisterer M, Gordon D, Peterson K, Ashburn W. Left ventricular volumes by gated equilibrium radionuclide angiography: a new method. Circulation. 1979 Sep; 60(3):556-64. PMID: 455618.
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      151. Slutsky R, Gordon D, Karliner J, Battler A, Walaski S, Verba J, Pfisterer M, Peterson K, Ashburn W. Assessment of early ventricular systole by first pass radionuclide angiography: useful method for detection of left ventricular dysfunction at rest in patients with coronary artery disease. Am J Cardiol. 1979 Sep; 44(3):459-65. PMID: 474426.
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      152. Pouleur H, Karliner JS, LeWinter MM, Covell JW. Diastolic viscous properties of the intact canine left ventricle. Circ Res. 1979 Sep; 45(3):410-9. PMID: 455608.
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      153. Slutsky R, Karliner J, Battler A, Pfisterer M, Swanson S, Ashburn W. Reproducibility of ejection fraction and ventricular volume by gated radionuclide angiography after myocardial infarction. Radiology. 1979 Jul; 132(1):155-9. PMID: 451192.
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      154. Johnson AD, Karliner JS, Ross J. Clinical use of vasodilators in cardiac disorders. Med Times. 1979 May; 107(5):53-64. PMID: 449641.
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      155. Engler R, Ryan W, LeWinter M, Bluestein H, Karliner JS. Assessment of long-term antiarrhythmic therapy: studies on the long-term efficacy and toxicity of tocainide. Am J Cardiol. 1979 Mar; 43(3):612-8. PMID: 420111.
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      156. Ryan WF, Karliner JS. Effects of tocainide on left ventricular performance at rest and during acute alterations in heart rate and systemic arterial pressure. An echocardiographic study. Br Heart J. 1979 Feb; 41(2):175-81. PMID: 371645; PMCID: PMC486846.
      157. Ryan W, Engler R, LeWinter M, Karliner JS. Efficacy of a new oral agent (tocainide) in the acute treatment of refractory ventricular arrhythmias. Am J Cardiol. 1979 Feb; 43(2):285-91. PMID: 760482.
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      158. Gregoratos G, Karliner JS. Infective endocarditis. Diagnosis and management. Med Clin North Am. 1979 Jan; 63(1):173-99. PMID: 581890.
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      159. LeWinter MM, Karliner JS, Covell JW. Alteration in heart rate response to hemorrhage in conscious dogs with volume overload. Am J Physiol. 1978 Oct; 235(4):H422-8. PMID: 696883.
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      160. Katz R, Karliner JS, Resnik R. Effects of a natural volume overload state (pregnancy) on left ventricular performance in normal human subjects. Circulation. 1978 Sep; 58(3 Pt 1):434-41. PMID: 679433.
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      161. Tobinick E, Schelbert HR, Henning H, LeWinter M, Taylor A, Ashburn WL, Karliner JS. Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography. Circulation. 1978 Jun; 57(6):1078-84. PMID: 639228.
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      162. Hardarson T, Henning H, O'Rourke RA, Karliner JS, Ryan W, Ross J. Variability, reproducibility, and applications of precordial ST-segment mapping following acute myocardial infarction. Circulation. 1978 Jun; 57(6):1096-103. PMID: 639230.
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      163. Henning H, O'Rourke RA, Crawford MH, Righetti A, Karliner JS. Inferior myocardial infarction as a cause of asymmetric septal hypertrophy. An echocardiographic study. Am J Cardiol. 1978 May 1; 41(5):817-22. PMID: 148208.
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      164. Lew W, Henning H, Schelbert H, Karliner JS. Assessment of mitral valve E point-septal separation as an index of left ventricular performance in patients with acute and previous myocardial infarction. Am J Cardiol. 1978 May 1; 41(5):836-45. PMID: 645591.
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      165. LeWinter MM, Karliner JS, O'Rourke RA. Effects of oral equiblocking doses of a cardioselective and noncardioselective beta-adrenergic blocking agent on left ventricular function in the normal conscious dog. Cardiovasc Res. 1978 Feb; 12(2):81-90. PMID: 647714.
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      166. Karliner JS. Clinical reliability of determining left ventricular function by echocardiography. Cardiovasc Clin. 1978; 9(2):151-65. PMID: 359144.
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      167. Karliner JS, LeWinter MM, Mahler F, Engler R, O'Rourke RA. Pharmacologic and hemodynamic influences on the rate of isovolumic left ventricular relaxation in the normal conscious dog. J Clin Invest. 1977 Sep; 60(3):511-21. PMID: 893662; PMCID: PMC372396.
      168. LeWinter MM, Crawford MH, O'Rourke RA, Karliner JS. The effects of oral propranolol, digoxin and combination therapy on the resting and exercise electrocardiogram. Am Heart J. 1977 Feb; 93(2):202-9. PMID: 319642.
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      169. Filner B, Karliner JS, Daily PO. Favorable influence of dopamine on left ventricular performance in patients refractory to discontinuation of cardiopulmonary bypass. Circ Shock. 1977; 4(3):223-30. PMID: 923019.
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      170. Crawford MH, Karliner JS, O'Rourke RA, Amon KW. Favorable effects of oral maintenance digoxin therapy on left ventricular performance in normal subjects: echocardiographic study. Am J Cardiol. 1976 Dec; 38(7):843-7. PMID: 998521.
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      171. Schelbert HR, Henning H, Ashburn WL, Verba JW, Karliner JS, O'Rourke RA. Serial measurements of left ventricular ejection fraction by radionuclide angiography early and late after myocardial infarction. Am J Cardiol. 1976 Oct; 38(4):407-15. PMID: 970327.
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      172. Henning H, Crawford MH, Karliner JS, O'Rourke RA. Beneficial effects of nitroglycerin on abnormal ventricular wall motion at rest and during exercise in patient with previous myocardial infarction. Am J Cardiol. 1976 Mar 31; 37(4):623-9. PMID: 1258801.
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      173. Roeske WR, O'Rourke RA, Klein A, Leopold G, Karliner JS. Noninvasive evaluation of ventricular hypertrophy in professional athletes. Circulation. 1976 Feb; 53(2):286-91. PMID: 128424.
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      174. Henning H, Schelbert H, Crawford MH, Karliner JS, Ashburn W, O'Rourke RA. Left ventricular performance assessed by radionuclide angiocardiography and echocardiography in patients with previous myocardial infarction. Circulation. 1975 Dec; 52(6):1069-75. PMID: 1182951.
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      175. Roeske WR, Higgins C, Karliner JS, Berk RN, O'Rourke RA. Incidence of arrhythmias and ST-segment changes in elderly patients during barium enema studies. Am Heart J. 1975 Dec; 90(6):688-94. PMID: 1199917.
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      176. Hirshleifer J, Crawford M, O'Rourke RA, Karliner JS. Influence of acute alterations in heart rate and systemic arterial pressure on echocardiographic measures of left ventricular perfornmance in normal human subjects. Circulation. 1975 Nov; 52(5):835-41. PMID: 1175264.
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      177. Crawford MH, LeWinter MM, O'Rourke RA, Karliner JS, Ross J. Combined propranolol and digoxin therapy in angina pectoris. Ann Intern Med. 1975 Oct; 83(4):449-55. PMID: 1101757.
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      178. Alpert JS, Crawford MH, Karliner JS, O'Rourke RA. Letter: STI in COPD. Circulation. 1975 Aug; 52(2):354-5. PMID: 1149215.
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      179. Unger K, Shaw D, Karliner JS, Crawford M, O'Rourke RA, Moser KM. Evaluation of left ventricular performance in acutely ill patients with chronic obstructive lung disease. Chest. 1975 Aug; 68(2):135-42. PMID: 1149544.
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      180. LeWinter MM, Crawford MH, Karliner JS, ORourke RA. Effects of oral propranolol in normal subjects. Clin Pharmacol Ther. 1975 Jun; 17(6):709-12. PMID: 1139862.
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      181. Mahler F, Karliner JS, O'Rourke RA. Effects of chronic digoxin administration on left ventricular performance in the normal conscious dog. Circulation. 1974 Oct; 50(4):720-7. PMID: 4418666.
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      182. Hagan AD, Francis GS, Sahn DJ, Karliner JS, Friedman WF, O'Rourke RA. Ultrasound evaluation of systolic anterior septal motion in patients with and without right ventricular volume overload. Circulation. 1974 Aug; 50(2):248-54. PMID: 4846632.
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      183. LeWinter MM, Hoffman JR, Shell WE, Karliner JS, O'Rourke RA. Phenylephrine-induced atypical chest pain in patients with prolapsing mitral valve leaflets. Am J Cardiol. 1974 Jul; 34(1):12-8. PMID: 4835748.
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      184. Shaw DJ, Crawford MH, Karliner JS, DiDonna G, Carleton RM, Ross J, O'Rourke RA. Arm-crank ergometry: a new method for the evaluation of coronary artery disease. Am J Cardiol. 1974 May 20; 33(6):801-5. PMID: 4824854.
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      185. Ludbrook P, Karliner JS, London A, Peterson KL, Leopold GR, O'Rourke RA. Posterior wall velocity: an unreliable index of total left ventricular performance in patients with coronary artery disease. Am J Cardiol. 1974 Apr; 33(4):475-82. PMID: 4818047.
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      186. Ludbrook P, Karliner JS, O'Rourke RA. Effects of submaximal isometric handgrip on left ventricular size and wall motion. Am J Cardiol. 1974 Jan; 33(1):30-6. PMID: 4808553.
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      187. Karliner JS, Gault JH, Bouchard RJ, Holzer J. Factors influencing the ejection fraction and the mean rate of circumferential fibre shortening during atrial fibrillation in man. Cardiovasc Res. 1974 Jan; 8(1):18-25. PMID: 4819485.
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      188. Ludbrook P, Karliner JS, Peterson K, Leopold G, O'Rourke RA. Comparison of ultrasound and cineangiographic measurements of left ventricular performance in patients with and without wall motion abnormalities. Br Heart J. 1973 Oct; 35(10):1026-32. PMID: 4759463; PMCID: PMC458747.
      189. Holzer J, Karliner JS, O'Rourke RA, Pitt W, Ross J. Effectiveness of dopamine in patients with cardiogenic shock. Am J Cardiol. 1973 Jul; 32(1):79-84. PMID: 4713114.
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      190. Ludbrook P, Karliner JS, Kostuk W, O'Rourke RA. Effects of intravenously administered propranolol on wall motion abnormalities. Am J Cardiol. 1973 Jun; 31(6):712-7. PMID: 4706728.
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      191. Eckberg DL, Gault JH, Bouchard RL, Karliner JS, Ross J. Mechanics of left ventricular contraction in chronic severe mitral regurgitation. Circulation. 1973 Jun; 47(6):1252-9. PMID: 4709542.
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      192. Laiken S, Laiken N, O'Rourke RA, Karliner JS. A rapid method for frontal plane axis determination in scalar electrocardiograms. Am Heart J. 1973 May; 85(5):620-3. PMID: 4266821.
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      193. Ashburn WL, Kostuk WJ, Karliner JS, Peterson KL, Sobel BE. Left ventricular volume and ejection fraction determination by radionuclide angiography. Semin Nucl Med. 1973 Apr; 3(2):165-76. PMID: 4696299.
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      194. Kostuk WJ, Ehsani AA, Karliner JS, Ashburn WL, Peterson KL, Ross J, Sobel BE. Left ventricular performance after myocardial infarction assessed by radioisotope angiocardiography. Circulation. 1973 Feb; 47(2):242-9. PMID: 4567867.
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      195. Karliner JS. Current aspects of digitalis therapy. W V Med J. 1973 Jan; 69(1):7-8. PMID: 4509349.
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      196. Cooper RH, O'Rourke RA, Karliner JS, Peterson KL, Leopold GR. Comparison of ultrasound and cineangiographic measurements of the mean rate of circumferential fiber shortening in man. Circulation. 1972 Nov; 46(5):914-23. PMID: 5081143.
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      197. Karliner JS. Current aspects of digitalis therapy. Med Ann Dist Columbia. 1972 Nov; 41(11):695-6. PMID: 4508226.
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      198. Karliner JS. Noncardiogenic forms of pulmonary edema. Circulation. 1972 Aug; 46(2):212-5. PMID: 5046017.
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      199. Johnson AD, O'Rourke RA, Karliner JS, Burian C. Effect of myocardial revascularization on systolic time intervals in patients with left ventricular dysfunction. Circulation. 1972 May; 45(1 Suppl):I91-6. PMID: 4537205.
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      200. Karliner JS, Braunwald E. Present status of digitalis treatment of acute myocardial infarction. Circulation. 1972 Apr; 45(4):891-902. PMID: 4259419.
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      201. Karliner JS, Ross J. Evaluation of myocardial contractility in man. G Ital Cardiol. 1972; 2(5):595-603. PMID: 5079018.
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      202. Karliner JS, Gander MP, Sobel BE. Elevated serum glyceraldehyde phosphate dehydrogenase activity following acute myocardial infarction. Chest. 1971 Oct; 60(4):318-23. PMID: 5115853.
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      203. Karliner JS, Gault JH, Eckberg D, Mullins CB, Ross J. Mean velocity of fiber shortening. A simplified measure of left ventricular myocardial contractility. Circulation. 1971 Sep; 44(3):323-33. PMID: 5097436.
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      204. Karliner JS, Bouchard RJ, Gault JH. Dimensional changes of the human left ventricle prior to aortic valve opening. A cineangiographic study in patients with and without left heart disease. Circulation. 1971 Sep; 44(3):312-22. PMID: 5097435.
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      205. Braunwald E, Karliner JS, Ashburn WL, Kazamias TM, Ross J, Maroko PR, Sobel BE, Braunwald NS. Research on the diagnosis and treatment of myocardial infarction. Calif Med. 1971 May; 114(5):44-63. PMID: 5092514; PMCID: PMC1501990.
      206. Karliner JS, Ross J. Left ventricular performance after acute myocardial infarction. Prog Cardiovasc Dis. 1971 Jan; 13(4):374-91. PMID: 5212392.
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      207. Goldschlager AW, Karliner JS. Ventricular standstill after intravenous diphenylhydantoin. Am Heart J. 1967 Sep; 74(3):410-2. PMID: 6068646.
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