John Fahy, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #1307
San Francisco CA 94143
Phone415-476-9940
ORCID ORCID Icon0000-0001-5427-9308 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Sequential, Multiple Assignment, Randomized Trial in Severe Asthma Protocol (SMART-SA)
    NIH UG1HL139106Sep 23, 2017 - Jun 30, 2023
    Role: Principal Investigator
    Carbohydrate-based Therapy for Lung Disease
    NIH P01HL128191Sep 1, 2016 - Jul 31, 2021
    Role: Principal Investigator
    Exploring the biology of persistent type 2 airway niches in asthma
    NIH 2P01HL107202-06A1Aug 15, 2012 - Jul 31, 2024
    Role: Principal Investigator
    Exploring the biology of persistent type 2 airway niches in asthma
    NIH P01HL107202Aug 15, 2012 - Jul 31, 2024
    Role: Principal Investigator
    Clinical and Molecular Phenotypes of Severe Asthma
    NIH U10HL109146Aug 8, 2011 - May 31, 2019
    Role: Principal Investigator
    Preventing fucose-dependent binding of aspergillus and pseudomonas to lung mucin
    NIH P50HL107191May 1, 2011 - Apr 30, 2015
    Role: Principal Investigator
    Mechanism of mucus pathology in asthma exacerbations
    NIH R01HL080414Jul 1, 2005 - Apr 30, 2021
    Role: Principal Investigator
    T CELL INFLAMMATION AND MUCIN HYPERSECRETION IN COPD
    NIH R01HL066564Aug 1, 2001 - Jul 31, 2005
    Role: Principal Investigator
    GOBLET CELL DYSFUNCTION IN ASTHMA
    NIH R01HL061662Dec 7, 1998 - Nov 30, 2003
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Collaboration Interests

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma. JCI Insight. 2024 Feb 08; 9(3). Huang BK, Elicker BM, Henry TS, Kallianos KG, Hahn LD, Tang M, Heng F, McCulloch CE, Bhakta NR, Majumdar S, Choi J, Denlinger LC, Fain SB, Hastie AT, Hoffman EA, Israel E, Jarjour NN, Levy BD, Mauger DT, Sumino K, Wenzel SE, Castro M, Woodruff PG, Fahy JV, Sarp FTNSARP. PMID: 38127464.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    2. A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma. Am J Respir Crit Care Med. 2023 Dec 19. Leung C, Tang M, Huang BK, Fain SB, Hoffman EA, Choi J, Dunican EM, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Levy BD, Wenzel SE, Sumino K, Hastie AT, Schirm J, McCulloch CE, Peters MC, Woodruff PG, Sorkness RL, Castro M, Fahy JV, NHLBI Severe Asthma Research Program (SARP). PMID: 38113166.
      View in: PubMed   Mentions:    Fields:    
    3. A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases. Eur Respir J. 2023 05; 61(5). Addante A, Raymond W, Gitlin I, Charbit A, Orain X, Scheffler AW, Kuppe A, Duerr J, Daniltchenko M, Drescher M, Graeber SY, Healy AM, Oscarson S, Fahy JV, Mall MA. PMID: 37080569; PMCID: PMC10209473.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    4. Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes. J Asthma. 2023 10; 60(10):1843-1852. Li H, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Wenzel SE, Zein J, Bleecker ER, Meyers DA, Chen Y, Li X, NHLBI Severe Asthma Research Program (SARP). PMID: 36940238; PMCID: PMC10528448.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes. J Asthma. 2023 10; 60(10):1824-1835. Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA, NHLBI Severe Asthma Research Program (SARP). PMID: 36946148; PMCID: PMC10524756.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma. J Allergy Clin Immunol. 2023 07; 152(1):94-106.e12. Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray A. PMID: 36893862; PMCID: PMC10330021.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity. Am J Respir Crit Care Med. 2023 02 15; 207(4):438-451. Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ER. PMID: 36066606; PMCID: PMC9940145.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    8. Skeletal Muscle Adiposity and Lung Function Trajectory in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2023 02 15; 207(4):475-484. Tattersall MC, Lee KE, Tsuchiya N, Osman F, Korcarz CE, Hansen KM, Peters MC, Fahy JV, Longhurst CA, Dunican E, Wentzel SE, Leader JK, Israel E, Levy BD, Castro M, Erzurum SC, Lempel J, Moore WC, Bleecker ER, Phillips BR, Mauger DT, Hoffman EA, Fain SB, Reeder SB, Sorkness RL, Jarjour NN, Denlinger LC, Schiebler ML. PMID: 36194556; PMCID: PMC9940151.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Reply to Nie et al. and Bhammar et al. Am J Respir Crit Care Med. 2023 01 01; 207(1):111-112. Peters MC, Schiebler ML, Mauger DT, Fahy JV. PMID: 36029296; PMCID: PMC9952864.
      View in: PubMed   Mentions:    Fields:    
    10. Reply to Ikeda and Tomita. Am J Respir Crit Care Med. 2022 11 15; 206(10):1299-1300. Tang M, Mauger DT, Fahy JV, Dunican EM. PMID: 35876128; PMCID: PMC9746837.
      View in: PubMed   Mentions:    Fields:    
    11. The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma. Am J Respir Crit Care Med. 2022 11 01; 206(9):1096-1106. Peters MC, Schiebler ML, Cardet JC, Johansson MW, Sorkness R, DeBoer MD, Bleecker ER, Meyers DA, Castro M, Sumino K, Erzurum SC, Tattersall MC, Zein JG, Hastie AT, Moore W, Levy BD, Israel E, Phillips BR, Mauger DT, Wenzel SE, Fajt ML, Koliwad SK, Denlinger LC, Woodruff PG, Jarjour NN, Fahy JV, National Heart, Lung, and Blood Institute Severe Asthma Research Program-3. PMID: 35687105; PMCID: PMC9704842.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    12. Urinary total conjugated 3-bromotyrosine, asthma severity, and exacerbation risk. Am J Physiol Lung Cell Mol Physiol. 2022 11 01; 323(5):L548-L557. Wang Z, Xu W, Comhair SAA, Fu X, Shao Z, Bearden R, Zein JG, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Mauger DT, Gaston B, Hazen SL, Erzurum SC. PMID: 36126269; PMCID: PMC9602918.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L372-L389. Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, Simmons G, Fahy JV. PMID: 35762590; PMCID: PMC9448286.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. DNA sequencing analysis of cystic fibrosis transmembrane conductance regulator gene identifies cystic fibrosis-associated variants in the Severe Asthma Research Program. Pediatr Pulmonol. 2022 07; 57(7):1782-1788. Izquierdo ME, Marion CR, Moore WC, Raraigh KS, Taylor-Cousar JL, Cutting GR, Ampleford E, Hawkins GA, Zein J, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Mauger D, Levy BD, Wenzel SE, Woodruff P, Bleecker ER, Meyers DA, Ortega VE. PMID: 35451201; PMCID: PMC9443928.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time. Am J Respir Crit Care Med. 2022 05 01; 205(9):1036-1045. Tang M, Elicker BM, Henry T, Gierada DS, Schiebler ML, Huang BK, Peters MC, Castro M, Hoffman EA, Fain SB, Ash SY, Choi J, Hall C, Phillips BR, Mauger DT, Denlinger LC, Jarjour NN, Israel E, Phipatanakul W, Levy BD, Wenzel SE, Bleecker ER, Woodruff PG, Fahy JV, Dunican EM. PMID: 35104436; PMCID: PMC9851493.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts. Radiology. 2022 08; 304(2):450-459. Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD, Hoffman EA, Castro M, Sheshadri A, NHLBI Severe Asthma Research Program (SARP). PMID: 35471111; PMCID: PMC9340243.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. The Mucin Gene MUC5B Is Required for Normal Lung Function. Am J Respir Crit Care Med. 2022 04 01; 205(7):737-739. Liegeois MA, Fahy JV. PMID: 35148488; PMCID: PMC9836220.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Obesity alters pathology and treatment response in inflammatory disease. Nature. 2022 04; 604(7905):337-342. Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Crotty Alexander LE, Suh JM, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee IK, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A. PMID: 35355021; PMCID: PMC9165753.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    19. Mucus secretion blocked at its source in the lungs. Nature. 2022 03; 603(7903):798-799. Gitlin I, Fahy JV. PMID: 35322214.
      View in: PubMed   Mentions: 1     Fields:    
    20. 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation. J Clin Invest. 2022 01 04; 132(1). Nagasaki T, Schuyler AJ, Zhao J, Samovich SN, Yamada K, Deng Y, Ginebaugh SP, Christenson SA, Woodruff PG, Fahy JV, Trudeau JB, Stoyanovsky D, Ray A, Tyurina YY, Kagan VE, Wenzel SE. PMID: 34762602; PMCID: PMC8718153.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    21. Mucus Plugs in Asthma at CT Associated with Regional Ventilation Defects at 3He MRI. Radiology. 2022 04; 303(1):184-190. Mummy DG, Dunican EM, Carey KJ, Evans MD, Elicker BM, Newell JD, Gierada DS, Nagle SK, Schiebler ML, Sorkness RL, Jarjour NN, Denlinger LC, Fahy JV, Fain SB. PMID: 34931858; PMCID: PMC8962781.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    22. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 02; 149(2):488-516.e9. Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P, PrecISE Study Team. PMID: 34848210; PMCID: PMC8821377.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    23. Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE2 in vitro. bioRxiv. 2021 Nov 11. Khanna K, Raymond W, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Pillai S, Healy AM, Duff T, Oscarson S, Hoffmann M, Pöhlmann S, Simmons G, Fahy JV. PMID: 33330868; PMCID: PMC7743076.
      View in: PubMed   Mentions:
    24. Benefits of Airway Androgen Receptor Expression in Human Asthma. Am J Respir Crit Care Med. 2021 08 01; 204(3):285-293. Zein JG, McManus JM, Sharifi N, Erzurum SC, Marozkina N, Lahm T, Giddings O, Davis MD, DeBoer MD, Comhair SA, Bazeley P, Kim HJ, Busse W, Calhoun W, Castro M, Chung KF, Fahy JV, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Ortega VE, Peters M, Bleecker ER, Meyers DA, Zhao Y, Wenzel SE, Gaston B. PMID: 33779531; PMCID: PMC8513596.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    25. Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 04 21; 13(1):66. Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. PMID: 33883027; PMCID: PMC8059115.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    26. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. Am J Respir Crit Care Med. 2021 04 15; 203(8):957-968. Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler R, Christenson SA, Comellas A, Cooper CB, Couper D, Criner GJ, Dransfield M, Doerschuk CM, Drummond MB, Hansel NN, Han MK, Hastie AT, Hoffman EA, Krishnan JA, Lazarus SC, Martinez FJ, McCulloch CE, O'Neal WK, Ortega VE, Paine R, Peters S, Schroeder JD, Woodruff PG, Fahy JV. PMID: 33180550; PMCID: PMC8048745.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    27. Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma. Am J Respir Crit Care Med. 2021 04 01; 203(7):841-852. Denlinger LC, Phillips BR, Sorkness RL, Bleecker ER, Castro M, DeBoer MD, Fitzpatrick AM, Hastie AT, Gaffin JM, Moore WC, Peters MC, Peters SP, Phipatanakul W, Cardet JC, Erzurum SC, Fahy JV, Fajt ML, Gaston B, Levy BD, Meyers DA, Ross K, Teague WG, Wenzel SE, Woodruff PG, Zein J, Jarjour NN, Mauger DT, Israel E. PMID: 33290668; PMCID: PMC8017577.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2021 04 01; 203(7):882-892. Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ER. PMID: 33545021; PMCID: PMC8017570.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    29. PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment. J Allergy Clin Immunol. 2021 05; 147(5):1594-1601. Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. PMID: 33667479; PMCID: PMC8113113.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    30. Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: Results from SARP-3. J Allergy Clin Immunol. 2021 09; 148(3):752-762. Krings JG, Goss CW, Lew D, Samant M, McGregor MC, Boomer J, Bacharier LB, Sheshadri A, Hall C, Brownell J, Schechtman KB, Peterson S, McEleney S, Mauger DT, Fahy JV, Fain SB, Denlinger LC, Israel E, Washko G, Hoffman E, Wenzel SE, Castro M, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program Investigators. PMID: 33577895; PMCID: PMC8349941.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Erratum: COVID-19-related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids. Am J Respir Crit Care Med. 2020 12 15; 202(12):1744-1746. Peters MC, Fahy JV. PMID: 33320072; PMCID: PMC7737596.
      View in: PubMed   Mentions: 2     Fields:    
    32. The Use of a Three-Fluid Atomising Nozzle in the Production of Spray-Dried Theophylline/Salbutamol Sulphate Powders Intended for Pulmonary Delivery. Pharmaceutics. 2020 Nov 20; 12(11). Focaroli S, Jiang G, O'Connell P, Fahy JV, Healy AM. PMID: 33233520; PMCID: PMC7699582.
      View in: PubMed   Mentions: 1  
    33. Reply to Nannini and to Lipworth et al. Am J Respir Crit Care Med. 2020 11 01; 202(9):1325-1326. Peters MC, Fahy JV, Denlinger LC. PMID: 32687407; PMCID: PMC7605204.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency. Am J Respir Crit Care Med. 2020 10 01; 202(7):973-982. Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, Fahy JV, Denlinger LC. PMID: 32479111; PMCID: PMC7528796.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    35. The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations. J Biopharm Stat. 2020 11 01; 30(6):1026-1037. Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. PMID: 32941098; PMCID: PMC7954787.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    36. Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways. J Allergy Clin Immunol. 2021 03; 147(3):894-909. Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, Woodruff PG, Kaminski N, Wenzel SE, Bleecker ER, Meyers DA, NHLBI Severe Asthma Research Program (SARP). PMID: 32795586; PMCID: PMC7876167.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    37. An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells. Clin Exp Allergy. 2020 08; 50(8):904-914. Kerr SC, Gonzalez JR, Schanin J, Peters MC, Lambrecht BN, Brock EC, Charbit A, Ansel KM, Youngblood BA, Fahy JV. PMID: 32542913; PMCID: PMC7610812.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    38. COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids. Am J Respir Crit Care Med. 2020 07 01; 202(1):83-90. Peters MC, Sajuthi S, Deford P, Christenson S, Rios CL, Montgomery MT, Woodruff PG, Mauger DT, Erzurum SC, Johansson MW, Denlinger LC, Jarjour NN, Castro M, Hastie AT, Moore W, Ortega VE, Bleecker ER, Wenzel SE, Israel E, Levy BD, Seibold MA, Fahy JV. PMID: 32348692; PMCID: PMC7328313.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansCellsPHPublic Health
    39. Baseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort. J Allergy Clin Immunol. 2020 07; 146(1):222-226. Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips B, Wenzel SE, Fahy JV, Israel E, Bleecker ER, NHLBI SARP 3 Investigators. PMID: 32032631; PMCID: PMC7343602.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    40. An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma. Cell. 2020 Jan 23; 180(2):406. Maun HR, Jackman JK, Choy DF, Loyet KM, Staton TL, Jia G, Dressen A, Hackney JA, Bremer M, Walters BT, Vij R, Chen X, Trivedi NN, Morando A, Lipari MT, Franke Y, Wu X, Zhang J, Liu J, Wu P, Chang D, Orozco LD, Christensen E, Wong M, Corpuz R, Hang JQ, Lutman J, Sukumaran S, Wu Y, Ubhayakar S, Liang X, Schwartz LB, Babina M, Woodruff PG, Fahy JV, Ahuja R, Caughey GH, Kusi A, Dennis MS, Eigenbrot C, Kirchhofer D, Austin CD, Wu LC, Koerber JT, Lee WP, Yaspan BL, Alatsis KR, Arron JR, Lazarus RA, Yi T. PMID: 31978350.
      View in: PubMed   Mentions: 2     Fields:    
    41. HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2187-2193. Zein J, Gaston B, Bazeley P, DeBoer MD, Igo RP, Bleecker ER, Meyers D, Comhair S, Marozkina NV, Cotton C, Patel M, Alyamani M, Xu W, Busse WW, Calhoun WJ, Ortega V, Hawkins GA, Castro M, Chung KF, Fahy JV, Fitzpatrick AM, Israel E, Jarjour NN, Levy B, Mauger DT, Moore WC, Noel P, Peters SP, Teague WG, Wenzel SE, Erzurum SC, Sharifi N. PMID: 31932420; PMCID: PMC6995013.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    42. Severe asthma during childhood and adolescence: A longitudinal study. J Allergy Clin Immunol. 2020 01; 145(1):140-146.e9. Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, Israel E, Levy B, Fahy JV, Castro M, Bleecker ER, Meyers D, Moore WC, Wenzel SE, Jarjour NN, Erzurum SC, Teague WG, Gaston B. PMID: 31622688.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsCTClinical Trials
    43. Development and initial validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2020 01; 145(1):127-139. Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN. PMID: 31604088; PMCID: PMC6949388.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    44. An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma. Cell. 2019 Oct 03; 179(2):417-431.e19. Maun HR, Jackman JK, Choy DF, Loyet KM, Staton TL, Jia G, Dressen A, Hackney JA, Bremer M, Walters BT, Vij R, Chen X, Trivedi NN, Morando A, Lipari MT, Franke Y, Wu X, Zhang J, Liu J, Wu P, Chang D, Orozco LD, Christensen E, Wong M, Corpuz R, Hang JQ, Lutman J, Sukumaran S, Wu Y, Ubhayakar S, Liang X, Schwartz LB, Babina M, Woodruff PG, Fahy JV, Ahuja R, Caughey GH, Kusi A, Dennis MS, Eigenbrot C, Kirchhofer D, Austin CD, Wu LC, Koerber JT, Lee WP, Yaspan BL, Alatsis KR, Arron JR, Lazarus RA, Yi T. PMID: 31585081; PMCID: PMC8403554.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    45. The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes. Eur J Pharm Biopharm. 2019 Nov; 144:139-153. Mah PT, O'Connell P, Focaroli S, Lundy R, O'Mahony TF, Hastedt JE, Gitlin I, Oscarson S, Fahy JV, Healy AM. PMID: 31536784; PMCID: PMC6938683.
      View in: PubMed   Mentions: 8     Fields:    
    46. Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort. Chest. 2020 02; 157(2):258-267. Ash SY, Sanchez-Ferrero GV, Schiebler ML, Rahaghi FN, Rai A, Come CE, Ross JC, Colon AG, Cardet JC, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Lempel JK, Mauger DT, Tattersall MC, Wenzel SE, Levy BD, Washko GR, Israel E, San Jose Estepar R, SARP Investigators. PMID: 31521672; PMCID: PMC7005378.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma. J Allergy Clin Immunol. 2020 01; 145(1):430-433. Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, Meyers DA, Fahy JV, Bleecker ER, National Heart, Lung, and Blood Institute's Severe Asthma Research Program (SARP) Networks. PMID: 31513878; PMCID: PMC7469890.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    48. Making Asthma Crystal Clear. N Engl J Med. 2019 08 29; 381(9):882-884. Fahy JV, Locksley RM. PMID: 31461600.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    49. Clinical significance of the bronchodilator response in children with severe asthma. Pediatr Pulmonol. 2019 11; 54(11):1694-1703. Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-DeClue H, Boomer JS, Castro M. PMID: 31424170; PMCID: PMC7015037.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med. 2019 06 01; 199(11):1358-1367. Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE. PMID: 30682261; PMCID: PMC6543720.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    51. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 05 23; 380(21):2009-2019. Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA, National Heart, Lung, and Blood Institute AsthmaNet. PMID: 31112384; PMCID: PMC6711475.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    52. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med. 2019 05 01; 199(9):1076-1085. Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV. PMID: 30888839; PMCID: PMC6515873.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    53. The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium. JCI Insight. 2019 04 18; 4(8). Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, Mauger DT, Dakhama A, Gellatly S, Pavelka N, Berman R, Di YP, Wenzel SE, Chu HW. PMID: 30996135; PMCID: PMC6538329.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    54. The Cytokines of Asthma. Immunity. 2019 04 16; 50(4):975-991. Lambrecht BN, Hammad H, Fahy JV. PMID: 30995510.
      View in: PubMed   Mentions: 333     Fields:    Translation:HumansAnimalsCells
    55. A Design of Experiment (DoE) approach to optimise spray drying process conditions for the production of trehalose/leucine formulations with application in pulmonary delivery. Int J Pharm. 2019 May 01; 562:228-240. Focaroli S, Mah PT, Hastedt JE, Gitlin I, Oscarson S, Fahy JV, Healy AM. PMID: 30849470; PMCID: PMC6562166.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    56. A Transcriptomic Method to Determine Airway Immune Dysfunction in T2-High and T2-Low Asthma. Am J Respir Crit Care Med. 2019 02 15; 199(4):465-477. Peters MC, Ringel L, Dyjack N, Herrin R, Woodruff PG, Rios C, O'Connor B, Fahy JV, Seibold MA. PMID: 30371106; PMCID: PMC6376622.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    57. Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2019 06; 143(6):2052-2061. Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG. PMID: 30635198; PMCID: PMC6556425.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    58. Purpose of the Conference: The 2018 Transatlantic Conference on Lung Diseases. Ann Am Thorac Soc. 2018 11; 15(Suppl 3):S139. MacNee W, Fahy JV, Nicod LP, Kolls J. PMID: 30431342.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Autopsy and Imaging Studies of Mucus in Asthma. Lessons Learned about Disease Mechanisms and the Role of Mucus in Airflow Obstruction. Ann Am Thorac Soc. 2018 11; 15(Suppl 3):S184-S191. Dunican EM, Watchorn DC, Fahy JV. PMID: 30431352; PMCID: PMC6322032.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    60. Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol. 2018 08 03; 3(26). Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD, National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators. PMID: 30076281; PMCID: PMC6320225.
      View in: PubMed   Mentions: 100     Fields:    
    61. Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med. 2018 07 01; 198(1):39-50. Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR, SARP Investigators. PMID: 29672122; PMCID: PMC6034125.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    62. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med. 2018 Apr 10; 18(1):58. DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W. PMID: 29631584; PMCID: PMC5891903.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    63. ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2018 03 22; 3(6). Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD, National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators. PMID: 29563345; PMCID: PMC5926903.
      View in: PubMed   Mentions: 3     Fields:    
    64. Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol. 2019 01; 143(1):104-113.e14. Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Wenzel SE, Fahy JV, National Heart, Lung and Blood Institute Severe Asthma Research Program 3. PMID: 29524537; PMCID: PMC6128784.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    65. Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. Cell Discov. 2018; 4:7. Lachowicz-Scroggins ME, Gordon ED, Wesolowska-Andersen A, Jackson ND, MacLeod HJ, Sharp LZ, Sun M, Seibold MA, Fahy JV. PMID: 29449961; PMCID: PMC5809386.
      View in: PubMed   Mentions: 8  
    66. Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest. 2018 03 01; 128(3):997-1009. Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV, National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP). PMID: 29400693; PMCID: PMC5824874.
      View in: PubMed   Mentions: 146     Fields:    Translation:Humans
    67. IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma. Am J Respir Crit Care Med. 2018 02 01; 197(3):313-324. Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. PMID: 29064281; PMCID: PMC5811952.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    68. Purpose of the Conference: The 2017 Transatlantic Conference on Lung Diseases. Ann Am Thorac Soc. 2017 11; 14(Suppl_5):S313. MacNee W, Fahy JV, Nicod LP, Kolls J. PMID: 29161085; PMCID: PMC5946628.
      View in: PubMed   Mentions:    Fields:    
    69. Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control. Chest. 2018 02; 153(2):378-386. Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC, National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. PMID: 29080709; PMCID: PMC5815875.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    70. Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia. Clin Exp Allergy. 2017 Dec; 47(12):1534-1545. Lachowicz-Scroggins ME, Finkbeiner WE, Gordon ED, Yuan S, Zlock L, Bhakta NR, Woodruff PG, Fahy JV, Boushey HA. PMID: 28833774.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    71. After asthma: redefining airways diseases. Lancet. 2018 01 27; 391(10118):350-400. Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A. PMID: 28911920.
      View in: PubMed   Mentions: 312     Fields:    Translation:HumansPHPublic Health
    72. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):545-554.e4. Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN. PMID: 28866107; PMCID: PMC5832534.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    73. ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2017 Jul 20; 2(14). Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD, National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. PMID: 28724795; PMCID: PMC5518567.
      View in: PubMed   Mentions: 17     Fields:    
    74. Asthma and corticosteroids: time for a more precise approach to treatment. Eur Respir J. 2017 06; 49(6). Dunican EM, Fahy JV. PMID: 28663322.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    75. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med. 2017 06 01; 195(11):1439-1448. Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E, Severe Asthma Research Program. PMID: 27967215; PMCID: PMC5470749.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    76. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol. 2017 Mar 10; 2(9). Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. PMID: 28783702; PMCID: PMC5561743.
      View in: PubMed   Mentions: 43     Fields:    
    77. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 02 01; 195(3):302-313. Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. PMID: 27556234; PMCID: PMC5328178.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCellsCTClinical Trials
    78. Purpose of the Conference: 2016 Transatlantic Airway Conference. Ann Am Thorac Soc. 2016 12; 13 Suppl 5:S395. MacNee W, Fahy JV, Nicod LP, Kolls JK. PMID: 28005426; PMCID: PMC5946651.
      View in: PubMed   Mentions: 1     Fields:    
    79. Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma. Am J Respir Crit Care Med. 2016 11 15; 194(10):1296-1299. Lachowicz-Scroggins ME, Yuan S, Kerr SC, Dunican EM, Yu M, Carrington SD, Fahy JV. PMID: 27845589; PMCID: PMC5114443.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    80. Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization. Ann Am Thorac Soc. 2016 11; 13(11):2103-2104. Dickey BF, Fahy JV, Kesimer M, Boucher RC, Evans CM, Thornton D. PMID: 27831803; PMCID: PMC5802559.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    81. Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III. Chest. 2016 Dec; 150(6):1242-1250. Luyster FS, Strollo PJ, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE. PMID: 27720882; PMCID: PMC5310183.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    82. IL1RL1 asthma risk variants regulate airway type 2 inflammation. JCI Insight. 2016 09 08; 1(14):e87871. Gordon ED, Palandra J, Wesolowska-Andersen A, Ringel L, Rios CL, Lachowicz-Scroggins ME, Sharp LZ, Everman JL, MacLeod HJ, Lee JW, Mason RJ, Matthay MA, Sheldon RT, Peters MC, Nocka KH, Fahy JV, Seibold MA. PMID: 27699235; PMCID: PMC5033813.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    83. Metabolic consequences of obesity as an "outside in" mechanism of disease severity in asthma. Eur Respir J. 2016 08; 48(2):291-3. Peters MC, Fahy JV. PMID: 27478182; PMCID: PMC6020152.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    84. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):8765-70. Gordon ED, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff PG, Ansel KM, Nocka K, Seibold MA, Fahy JV. PMID: 27432971; PMCID: PMC4978244.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    85. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. Lancet Respir Med. 2016 07; 4(7):574-584. Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JV, National Heart, Lung, and Blood Institute Severe Asthma Research Program. PMID: 27283230; PMCID: PMC5007068.
      View in: PubMed   Mentions: 189     Fields:    Translation:Humans
    86. Cross-Talk between Epithelial Cells and Type 2 Immune Signaling. The Role of IL-25. Am J Respir Crit Care Med. 2016 05 01; 193(9):935-6. Gordon ED, Locksley RM, Fahy JV. PMID: 27128698; PMCID: PMC4872659.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    87. Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma. J Allergy Clin Immunol. 2017 01; 139(1):72-81.e1. Sweerus K, Lachowicz-Scroggins M, Gordon E, LaFemina M, Huang X, Parikh M, Kanegai C, Fahy JV, Frank JA. PMID: 27215490; PMCID: PMC5073041.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    88. FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. PLoS Pathog. 2016 Apr; 12(4):e1005555. Kerr SC, Fischer GJ, Sinha M, McCabe O, Palmer JM, Choera T, Lim FY, Wimmerova M, Carrington SD, Yuan S, Lowell CA, Oscarson S, Keller NP, Fahy JV. PMID: 27058347; PMCID: PMC4825926.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    89. Mast cells in asthma: biomarker and therapeutic target. Eur Respir J. 2016 Apr; 47(4):1040-2. Reber LL, Fahy JV. PMID: 27037311.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    90. Asthma Was Talking, But We Weren't Listening. Missed or Ignored Signals That Have Slowed Treatment Progress. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S78-82. Fahy JV. PMID: 27027957; PMCID: PMC5015736.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    91. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. PMID: 26305520; PMCID: PMC4731702.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    92. Purpose of the Conference: 2015 Transatlantic Airway Conference. Ann Am Thorac Soc. 2015 Nov; 12 Suppl 2:S111. MacNee W, Fahy J, Nicod L, Kolls J. PMID: 26595725; PMCID: PMC5467081.
      View in: PubMed   Mentions:    Fields:    
    93. The Role of Type 2 Inflammation in the Pathogenesis of Asthma Exacerbations. Ann Am Thorac Soc. 2015 Nov; 12 Suppl 2:S144-9. Dunican EM, Fahy JV. PMID: 26595730; PMCID: PMC5467082.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    94. Oxidation increases mucin polymer cross-links to stiffen airway mucus gels. Sci Transl Med. 2015 Feb 25; 7(276):276ra27. Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV. PMID: 25717100; PMCID: PMC4403633.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    95. Type 2 inflammation in asthma--present in most, absent in many. Nat Rev Immunol. 2015 Jan; 15(1):57-65. Fahy JV. PMID: 25534623; PMCID: PMC4390063.
      View in: PubMed   Mentions: 559     Fields:    Translation:HumansAnimalsCells
    96. Twenty-Ninth Transatlantic Airway Conference. Innate and adaptive immune responses in airway disease. Purpose of the conference. Ann Am Thorac Soc. 2014 Dec; 11 Suppl 5:S233. MacNee W, Fahy J, Nicod L, Kolls J. PMID: 25525724.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    97. A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production. Nat Immunol. 2014 Dec; 15(12):1162-70. Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM. PMID: 25362490; PMCID: PMC4233009.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    98. Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One. 2014; 9(6):e99084. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS. PMID: 24915147; PMCID: PMC4051692.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    99. Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma. Am J Respir Crit Care Med. 2014 Apr 15; 189(8):1005-7. Kerr SC, Carrington SD, Oscarson S, Gallagher ME, Solon M, Yuan S, Ahn JN, Dougherty RH, Finkbeiner WE, Peters MC, Fahy JV. PMID: 24735037; PMCID: PMC4098098.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    100. Asthma and the flu: a tricky two-step. Immunol Cell Biol. 2014 May-Jun; 92(5):389-91. Locksley RM, Fahy JV. PMID: 24687019; PMCID: PMC4396068.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    101. Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Ann Am Thorac Soc. 2014 Apr; 11 Suppl 3:S139-45. Jackson DJ, Hartert TV, Martinez FD, Weiss ST, Fahy JV. PMID: 24754822; PMCID: PMC4112503.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansPHPublic Health
    102. A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity. PLoS One. 2013; 8(12):e83077. Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr SC, Lahmann M, Balloy V, Fahy JV, Chignard M, Imberty A, Wimmerova M. PMID: 24340081; PMCID: PMC3858362.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    103. Purpose of the conference. Ann Am Thorac Soc. 2013 Dec; 10 Suppl:S107. MacNee W, Fahy J, Nicod L, Wanner A. PMID: 24313758.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    104. Chair's summary: Mechanisms of relevance to clinical heterogeneity of asthma and chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2013 Dec; 10 Suppl:S108. Fahy JV. PMID: 24313759; PMCID: PMC5478182.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    105. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. 2014 Feb; 133(2):388-94. Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV. PMID: 24075231; PMCID: PMC3981552.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansCells
    106. Type 2 immune responses in obese individuals with asthma. Am J Respir Crit Care Med. 2013 Sep 15; 188(6):633-4. Peters MC, Fahy JV. PMID: 24032378.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    107. A qPCR-based metric of Th2 airway inflammation in asthma. Clin Transl Allergy. 2013 Jul 17; 3(1):24. Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG. PMID: 23866775; PMCID: PMC3724712.
      View in: PubMed   Mentions: 35  
    108. An integrated nano-scale approach to profile miRNAs in limited clinical samples. Am J Clin Exp Immunol. 2012 Nov 30; 1(2):70-89. Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM. PMID: 23304658; PMCID: PMC3538381.
      View in: PubMed   Mentions: 24  
    109. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):28-33. Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF, NHLBI Asthma Clinical Research Network Investigators. PMID: 23144325; PMCID: PMC3570642.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    110. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. PMID: 22988107; PMCID: PMC3479591.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    111. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA, Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. PMID: 22968888; PMCID: PMC3697088.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    112. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol. 2012 Sep; 130(3):647-654.e10. Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR, Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) . PMID: 22857879; PMCID: PMC3626285.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansCells
    113. Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. BMC Med Genomics. 2012 Jun 19; 5:27. Diez D, Goto S, Fahy JV, Erle DJ, Woodruff PG, Wheelock ÅM, Wheelock CE. PMID: 22713245; PMCID: PMC3408345.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    114. Cluster analysis of obesity and asthma phenotypes. PLoS One. 2012; 7(5):e36631. Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY, Asthma Clinical Research Network. PMID: 22606276; PMCID: PMC3350517.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCTClinical Trials
    115. Asthma outcomes: biomarkers. J Allergy Clin Immunol. 2012 Mar; 129(3 Suppl):S9-23. Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA, Schleimer RP, Minnicozzi M. PMID: 22386512; PMCID: PMC3390196.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    116. A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):612-9. McGrath KW, Icitovic N, Boushey HA, Lazarus SC, Sutherland ER, Chinchilli VM, Fahy JV, Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. PMID: 22268133; PMCID: PMC3326288.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansCTClinical Trials
    117. Genetic association between human chitinases and lung function in COPD. Hum Genet. 2012 Jul; 131(7):1105-14. Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ. PMID: 22200767; PMCID: PMC3771523.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    118. A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness. Clin Exp Allergy. 2012 Jan; 42(1):144-55. Gordon ED, Sidhu SS, Wang ZE, Woodruff PG, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV. PMID: 22093101; PMCID: PMC3271792.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    119. The airway epithelium as a regulator of Th2 responses in asthma. Am J Respir Crit Care Med. 2011 Aug 15; 184(4):390-2. Fahy JV, Locksley RM. PMID: 21844510.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    120. The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-α-1,3-galactose. J Allergy Clin Immunol. 2011 May; 127(5):1286-93.e6. Commins SP, James HR, Kelly LA, Pochan SL, Workman LJ, Perzanowski MS, Kocan KM, Fahy JV, Nganga LW, Ronmark E, Cooper PJ, Platts-Mills TA. PMID: 21453959; PMCID: PMC3085643.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansAnimals
    121. Hexaphenylbenzene as a rigid template for the straightforward syntheses of "star-shaped" glycodendrimers. J Org Chem. 2011 Jan 21; 76(2):724-7. Chabre YM, Brisebois PP, Abbassi L, Kerr SC, Fahy JV, Marcotte I, Roy R. PMID: 21190367; PMCID: PMC3981551.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    122. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. J Immunol. 2011 Feb 01; 186(3):1861-9. Choy DF, Modrek B, Abbas AR, Kummerfeld S, Clark HF, Wu LC, Fedorowicz G, Modrusan Z, Fahy JV, Woodruff PG, Arron JR. PMID: 21187436; PMCID: PMC3981556.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    123. Airway mucus function and dysfunction. N Engl J Med. 2010 Dec 02; 363(23):2233-47. Fahy JV, Dickey BF. PMID: 21121836; PMCID: PMC4048736.
      View in: PubMed   Mentions: 656     Fields:    Translation:Humans
    124. Negative methacholine challenge tests in subjects who report physician-diagnosed asthma. Clin Exp Allergy. 2011 Jan; 41(1):46-51. McGrath KW, Fahy JV. PMID: 21105916; PMCID: PMC3059141.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    125. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ, National Heart, Lung and Blood Institute's Asthma Clinical Research Network. PMID: 20920764; PMCID: PMC2950827.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    126. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER, National Heart, Lung, and Blood Institute Asthma Clinical Research Network. PMID: 20979471; PMCID: PMC3011177.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    127. The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation. Am J Respir Crit Care Med. 2011 Jan 15; 183(2):189-94. Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon MC, Carrington SD, Fahy JV. PMID: 20732988; PMCID: PMC3040389.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    128. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14170-5. Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L, Muller SJ, Fahy JV. PMID: 20660732; PMCID: PMC2922596.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansCells
    129. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol. 2010 May; 125(5):1046-1053.e8. Dougherty RH, Sidhu SS, Raman K, Solon M, Solberg OD, Caughey GH, Woodruff PG, Fahy JV. PMID: 20451039; PMCID: PMC2918406.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    130. Identifying clinical phenotypes of asthma: steps in the right direction. Am J Respir Crit Care Med. 2010 Feb 15; 181(4):296-7. Fahy JV. PMID: 20130143.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    131. Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):438-45. Woodruff PG, Wolff M, Hohlfeld JM, Krug N, Dransfield MT, Sutherland ER, Criner GJ, Kim V, Prasse A, Nivens MC, Tetzlaff K, Heilker R, Fahy JV. PMID: 20007923.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    132. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E, National Heart, Lung and Blood Institute's Asthma Clinical Research Network. PMID: 19932356; PMCID: PMC2914569.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    133. Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma. Am J Respir Crit Care Med. 2009 Oct 01; 180(7):603-10. Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff PG, Fahy JV, Erle DJ. PMID: 19628779; PMCID: PMC2753788.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    134. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med. 2009 Sep 01; 180(5):388-95. Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV. PMID: 19483109; PMCID: PMC2742757.
      View in: PubMed   Mentions: 730     Fields:    Translation:HumansCells
    135. Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. J Biol Chem. 2009 Jul 17; 284(29):19650-8. Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG. PMID: 19435888; PMCID: PMC2740590.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    136. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med. 2009 Aug 01; 180(3):203-10. Innes AL, Carrington SD, Thornton DJ, Kirkham S, Rousseau K, Dougherty RH, Raymond WW, Caughey GH, Muller SJ, Fahy JV. PMID: 19423716; PMCID: PMC2724713.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    137. Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies. Proc Am Thorac Soc. 2009 May 01; 6(3):256-9. Fahy JV. PMID: 19387026.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansCells
    138. Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype. Clin Exp Allergy. 2009 Feb; 39(2):193-202. Dougherty RH, Fahy JV. PMID: 19187331; PMCID: PMC2730743.
      View in: PubMed   Mentions: 139     Fields:    Translation:Humans
    139. Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. J Allergy Clin Immunol. 2008 Nov; 122(5):944-950.e3. Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG, Fahy JV. PMID: 18845328; PMCID: PMC2666777.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    140. Predicting worsening asthma control following the common cold. Eur Respir J. 2008 Dec; 32(6):1548-54. Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Ameredes BT, Bleecker ER, Calhoun WJ, Cherniack RM, Craig TJ, Denlinger LC, Israel E, Fahy JV, Jarjour NN, Kraft M, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Ramsdell JW, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Wechsler ME, National Heart, Lung and Blood Institute's Asthma Clinical Research Network. PMID: 18768579; PMCID: PMC2592508.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    141. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci U S A. 2007 Oct 02; 104(40):15858-63. Woodruff PG, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV. PMID: 17898169; PMCID: PMC2000427.
      View in: PubMed   Mentions: 360     Fields:    Translation:HumansCells
    142. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):783-90. Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske RF, Leone FT, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Wechsler ME, Fahy JV, National Heart Lung and Blood Institute's Asthma Clinical Research Network. PMID: 17204725; PMCID: PMC1899291.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    143. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol. 2007 Jan; 119(1):73-80. Martin RJ, Szefler SJ, King TS, Kraft M, Boushey HA, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fahy JV, Israel E, Lazarus SC, Lemanske RF, Leone FT, Pesola GR, Peters SP, Sorkness CA, Szwejbka LA, Wechsler ME, National Heart, Lung, and Blood Institute's Asthma Clinical Research Center. PMID: 17208587; PMCID: PMC2872157.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    144. Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction. Chest. 2006 Oct; 130(4):1102-8. Innes AL, Woodruff PG, Ferrando RE, Donnelly S, Dolganov GM, Lazarus SC, Fahy JV. PMID: 17035444.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    145. Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma. Am J Respir Crit Care Med. 2007 Feb 01; 175(3):228-34. Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Leone F, Lazarus SC, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Israel E, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 16973987; PMCID: PMC1899264.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    146. Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils. Am J Respir Crit Care Med. 2006 Nov 01; 174(9):1018-24. Hays SR, Fahy JV. PMID: 16917116; PMCID: PMC2648101.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    147. Anti-IgE: lessons learned from effects on airway inflammation and asthma exacerbation. J Allergy Clin Immunol. 2006 Jun; 117(6):1230-2. Fahy JV. PMID: 16750979.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    148. Effects of multiday exposure to ozone on airway inflammation as determined using sputum induction. Environ Health Perspect. 2006 Feb; 114(2):209-12. Ratto J, Wong H, Liu J, Fahy J, Boushey H, Solomon C, Balmes J. PMID: 16451856; PMCID: PMC1367833.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    149. beta-Adrenergic receptor polymorphisms and response to salmeterol. Am J Respir Crit Care Med. 2006 Mar 01; 173(5):519-26. Wechsler ME, Lehman E, Lazarus SC, Lemanske RF, Boushey HA, Deykin A, Fahy JV, Sorkness CA, Chinchilli VM, Craig TJ, DiMango E, Kraft M, Leone F, Martin RJ, Peters SP, Szefler SJ, Liu W, Israel E, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 16322642; PMCID: PMC2662935.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    150. Induced sputum evaluation in microwave popcorn production workers. Chest. 2005 Aug; 128(2):991-7. Akpinar-Elci M, Stemple KJ, Enright PL, Fahy JV, Bledsoe TA, Kreiss K, Weissman DN. PMID: 16100197.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    151. Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol. 2005 Aug; 116(2):305-11. Kuperman DA, Lewis CC, Woodruff PG, Rodriguez MW, Yang YH, Dolganov GM, Fahy JV, Erle DJ. PMID: 16083784.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    152. Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005 Apr 14; 352(15):1519-28. Boushey HA, Sorkness CA, King TS, Sullivan SD, Fahy JV, Lazarus SC, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fagan JK, Fish JE, Ford JG, Kraft M, Lemanske RF, Leone FT, Martin RJ, Mauger EA, Pesola GR, Peters SP, Rollings NJ, Szefler SJ, Wechsler ME, Israel E, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 15829533.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCTClinical Trials
    153. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. J Allergy Clin Immunol. 2005 Apr; 115(4):720-7. Deykin A, Lazarus SC, Fahy JV, Wechsler ME, Boushey HA, Chinchilli VM, Craig TJ, Dimango E, Kraft M, Leone F, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Israel E, Asthma Clinical Research Network, National Heart, Lung, and Blood Institute/NIH. PMID: 15805990.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCellsCTClinical Trials
    154. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet. 2004 Oct 23-29; 364(9444):1505-12. Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, Deykin A, Fagan JK, Fahy JV, Fish J, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Liggett SB, Martin RJ, Mitra N, Peters SP, Silverman E, Sorkness CA, Szefler SJ, Wechsler ME, Weiss ST, Drazen JM, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 15500895.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCTClinical Trials
    155. Adenosine up-regulation of the mucin gene, MUC2, in asthma. FASEB J. 2004 Nov; 18(14):1770-2. McNamara N, Gallup M, Khong A, Sucher A, Maltseva I, Fahy J, Basbaum C. PMID: 15345696.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    156. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med. 2004 Sep 15; 170(6):583-93. Djukanovic R, Wilson SJ, Kraft M, Jarjour NN, Steel M, Chung KF, Bao W, Fowler-Taylor A, Matthews J, Busse WW, Holgate ST, Fahy JV. PMID: 15172898.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansCTClinical Trials
    157. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med. 2004 May 01; 169(9):1001-6. Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD, Carter R, Wong HH, Cadbury PS, Fahy JV. PMID: 14726423.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    158. Effect of a single dose of the selectin inhibitor TBC1269 on early and late asthmatic responses. Clin Exp Allergy. 2004 Jan; 34(1):77-84. Avila PC, Boushey HA, Wong H, Grundland H, Liu J, Fahy JV. PMID: 14720266.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    159. Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma. Am J Med. 2003 Dec 01; 115(8):620-6. Janson SL, Fahy JV, Covington JK, Paul SM, Gold WM, Boushey HA. PMID: 14656614.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCellsCTClinical Trials
    160. Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens. J Allergy Clin Immunol. 2003 Dec; 112(6):1243-5. Ferrando RE, Nyengaard JR, Hays SR, Fahy JV, Woodruff PG. PMID: 14657892.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    161. Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids. Chest. 2003 Jul; 124(1):42-50. Kraft M, Martin RJ, Lazarus SC, Fahy JV, Boushey HA, Lemanske RF, Szefler SJ, Asthma Clinical Research Network. PMID: 12853500.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    162. The role of mucus in fatal asthma. Am J Med. 2003 Jul; 115(1):68-9. Hays SR, Fahy JV. PMID: 12867239.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    163. Goblet cell and mucin gene abnormalities in asthma. Chest. 2002 Dec; 122(6 Suppl):320S-326S. Fahy JV. PMID: 12475809.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    164. Airway remodeling in asthma. Semin Respir Crit Care Med. 2002 Aug; 23(4):361-7. Woodruff PG, Fahy JV. PMID: 16088629.
      View in: PubMed   Mentions: 9     Fields:    
    165. Systemic effect comparisons of six inhaled corticosteroid preparations. Am J Respir Crit Care Med. 2002 May 15; 165(10):1377-83. Martin RJ, Szefler SJ, Chinchilli VM, Kraft M, Dolovich M, Boushey HA, Cherniack RM, Craig TJ, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kunselman SJ, Lazarus SC, Lemanske RF, Peters SP, Sorkness CA. PMID: 12016099.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCTClinical Trials
    166. A role for neutrophils in asthma? Am J Med. 2002 Apr 15; 112(6):498-500. Woodruff PG, Fahy JV. PMID: 11959064.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    167. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol. 2002 Mar; 109(3):410-8. Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack RM, Chinchilli VM, Craig TJ, Dolovich M, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lazarus SC, Lemanske RF, Mauger E, Peters SP, Sorkness CA, Asthma Clinical Research Network of the National Heart Lung, and Blood Institute. PMID: 11897984.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansCTClinical Trials
    168. Practical management of acute asthma in adults. Respir Care. 2002 Feb; 47(2):171-82. Hallstrand TS, Fahy JV. PMID: 11812274.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    169. Quality control within the Asthma Clinical Research Network. Control Clin Trials. 2001 Dec; 22(6 Suppl):207S-21S. Martin RJ, Kephart DK, Dyer AM, Fahy J, Kraft M, Asthma Clinical Trials Network. PMID: 11728625.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    170. Remodeling of the airway epithelium in asthma. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 2):S46-51. Fahy JV. PMID: 11734466.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    171. Epithelial desquamation in asthma. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 1):1997. Ordoñez CL, Fahy JV. PMID: 11780603.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    172. Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol. 2001 Nov; 108(5):753-8. Woodruff PG, Khashayar R, Lazarus SC, Janson S, Avila P, Boushey HA, Segal M, Fahy JV. PMID: 11692100.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    173. A novel method of gene transcript profiling in airway biopsy homogenates reveals increased expression of a Na+-K+-Cl- cotransporter (NKCC1) in asthmatic subjects. Genome Res. 2001 Sep; 11(9):1473-83. Dolganov GM, Woodruff PG, Novikov AA, Zhang Y, Ferrando RE, Szubin R, Fahy JV. PMID: 11544191.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    174. Asthma: prevalence, pathogenesis, and prospects for novel therapies. JAMA. 2001 Jul 25; 286(4):395-8. Woodruff PG, Fahy JV. PMID: 11466111.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    175. Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2583-93. Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF, Sorkness CA, Kraft M, Fish JE, Peters SP, Craig T, Drazen JM, Ford JG, Israel E, Martin RJ, Mauger EA, Nachman SA, Spahn JD, Szefler SJ, Asthma Clinical Research Network for the National Heart, Lung, and Blood Institute. PMID: 11368732.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCTClinical Trials
    176. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2594-603. Lemanske RF, Sorkness CA, Mauger EA, Lazarus SC, Boushey HA, Fahy JV, Drazen JM, Chinchilli VM, Craig T, Fish JE, Ford JG, Israel E, Kraft M, Martin RJ, Nachman SA, Peters SP, Spahn JD, Szefler SJ, Asthma Clinical Research Network for the National Heart, Lung, and Blood Institute. PMID: 11368733.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCTClinical Trials
    177. Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med. 2001 May; 163(6):1470-5. Fahy JV, Boushey HA, Lazarus SC, Mauger EA, Cherniack RM, Chinchilli VM, Craig TJ, Drazen JM, Ford JG, Fish JE, Israel E, Kraft M, Lemanske RF, Martin RJ, McLean D, Peters SP, Sorkness C, Szefler SJ, NHLBI Asthma Clinical Research Network. PMID: 11371420.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCellsCTClinical Trials
    178. The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research. Chest. 2001 Apr; 119(4):1027-33. Leone FT, Mauger EA, Peters SP, Chinchilli VM, Fish JE, Boushey HA, Cherniack RM, Drazen JM, Fahy JV, Ford J, Israel E, Lazarus SC, Lemanske RF, Martin RJ, McGeady SJ, Sorkness C, Szefler SJ, Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. PMID: 11296165.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    179. "Reactive airways disease". A lazy term of uncertain meaning that should be abandoned. Am J Respir Crit Care Med. 2001 Mar; 163(4):822-3. Fahy JV, O'Byrne PM. PMID: 11282751.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    180. Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression. Am J Respir Crit Care Med. 2001 Feb; 163(2):517-23. Ordoñez CL, Khashayar R, Wong HH, Ferrando R, Wu R, Hyde DM, Hotchkiss JA, Zhang Y, Novikov A, Dolganov G, Fahy JV. PMID: 11179133.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansCells
    181. Relationship of epidermal growth factor receptors to goblet cell production in human bronchi. Am J Respir Crit Care Med. 2001 Feb; 163(2):511-6. Takeyama K, Fahy JV, Nadel JA. PMID: 11179132.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    182. Use of biological markers of airway inflammation to detect the efficacy of nurse-delivered asthma education. Heart Lung. 2001 Jan-Feb; 30(1):39-46. Janson S, Hardie G, Fahy J, Boushey H. PMID: 11174366.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    183. Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol. 2001 Jan-Mar; 124(1-3):183-6. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. PMID: 11306963.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    184. Histopathology of fatal asthma: drowning in mucus. Pediatr Pulmonol. 2001; Suppl 23:88-9. Rubin BK, Tomkiewicz R, Fahy JV, Green FH. PMID: 11886162; PMCID: PMC7167957.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    185. Targeting cytokines in asthma therapy: round one. Lancet. 2000 Dec 23-30; 356(9248):2114-6. Boushey HA, Fahy JV. PMID: 11191533.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    186. Epithelial desquamation in asthma: artifact or pathology? Am J Respir Crit Care Med. 2000 Dec; 162(6):2324-9. Ordoñez C, Ferrando R, Hyde DM, Wong HH, Fahy JV. PMID: 11112158.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    187. The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med. 2000 Jul; 162(1):75-80. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. PMID: 10903223.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCTClinical Trials
    188. Reducing IgE levels as a strategy for the treatment of asthma. Clin Exp Allergy. 2000 Jun; 30 Suppl 1:16-21. Fahy JV. PMID: 10849469.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    189. Predictors of late asthmatic response. Logistic regression and classification tree analyses. Am J Respir Crit Care Med. 2000 Jun; 161(6):2092-5. Avila PC, Segal MR, Wong HH, Boushey HA, Fahy JV. PMID: 10852792.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    190. Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance. Am J Respir Crit Care Med. 2000 Apr; 161(4 Pt 1):1185-90. Ordoñez CL, Shaughnessy TE, Matthay MA, Fahy JV. PMID: 10764310.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    191. Cytotoxic prenylxanthones from Garcinia bracteata. J Nat Prod. 2000 Apr; 63(4):441-6. Thoison O, Fahy J, Dumontet V, Chiaroni A, Riche C, Tri MV, Sévenet T. PMID: 10785410.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    192. Low- and high-dose fluticasone propionate in asthma; effects during and after treatment. Eur Respir J. 2000 Jan; 15(1):11-8. Gershman NH, Wong HH, Liu JT, Fahy JV. PMID: 10678614.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    193. Airway inflammation and remodeling in asthma. Curr Opin Pulm Med. 2000 Jan; 6(1):15-20. Fahy JV, Corry DB, Boushey HA. PMID: 10608420.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    194. Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells. J Clin Invest. 1999 Nov; 104(10):1375-82. Longphre M, Li D, Gallup M, Drori E, Ordoñez CL, Redman T, Wenzel S, Bice DE, Fahy JV, Basbaum C. PMID: 10562299; PMCID: PMC409835.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    195. Effect of aerosolized anti-IgE (E25) on airway responses to inhaled allergen in asthmatic subjects. Am J Respir Crit Care Med. 1999 Sep; 160(3):1023-7. Fahy JV, Cockcroft DW, Boulet LP, Wong HH, Deschesnes F, Davis EE, Ruppel J, Su JQ, Adelman DC. PMID: 10471635.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    196. Fractional analysis of sequential induced sputum samples during sputum induction: evidence that different lung compartments are sampled at different time points. J Allergy Clin Immunol. 1999 Aug; 104(2 Pt 1):322-8. Gershman NH, Liu H, Wong HH, Liu JT, Fahy JV. PMID: 10452752.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    197. The effect of methacholine challenge on the cellular composition of induced sputum. J Allergy Clin Immunol. 1999 May; 103(5 Pt 1):957-9. Gershman NH, Fahy JV. PMID: 10329838.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    198. Neutrophil elastase and elastase-rich cystic fibrosis sputum degranulate human eosinophils in vitro. Am J Physiol. 1999 01; 276(1):L28-34. Liu H, Lazarus SC, Caughey GH, Fahy JV. PMID: 9887052.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    199. A safe, simple, standardized method should be used for sputum induction for research purposes. Clin Exp Allergy. 1998 Sep; 28(9):1047-9. Fahy JV. PMID: 9761006.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    200. Targeting IgE with monoclonal antibodies: the future is now. Clin Exp Allergy. 1998 Jun; 28(6):664-7. Fahy JV, Boushey HA. PMID: 9677128.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    201. Effect of low-dose beclomethasone dipropionate on asthma control and airway inflammation. Eur Respir J. 1998 Jun; 11(6):1240-7. Fahy JV, Boushey HA. PMID: 9657561.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    202. Methods for sputum induction and analysis of induced sputum: a method for assessing airway inflammation in asthma. Eur Respir J Suppl. 1998 Mar; 26:9S-12S. Kips JC, Fahy JV, Hargreave FE, Ind PW, in't Veen JC. PMID: 9585872.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    203. An evaluation of colchicine as an alternative to inhaled corticosteriods in moderate asthma. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 1):1165-71. Fish JE, Peters SP, Chambers CV, McGeady SJ, Epstein KR, Boushey HA, Cherniack RM, Chinchilli VM, Drazen JM, Fahy JV, Hurd SS, Israel E, Lazarus SC, Lemanske RF, Martin RJ, Mauger EA, Sorkness C, Szefler SJ. PMID: 9351617.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    204. Safety of one method of sputum induction in asthmatic subjects. Am J Respir Crit Care Med. 1997 Jul; 156(1):299-303. Wong HH, Fahy JV. PMID: 9230765.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    205. The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects. Am J Respir Crit Care Med. 1997 Jun; 155(6):1828-34. Fahy JV, Fleming HE, Wong HH, Liu JT, Su JQ, Reimann J, Fick RB, Boushey HA. PMID: 9196082.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansCTClinical Trials
    206. Similar RANTES levels in healthy and asthmatic airways by immunoassay and in situ hybridization. Am J Respir Crit Care Med. 1997 Mar; 155(3):1095-100. Fahy JV, Figueroa DJ, Wong HH, Liu JT, Abrams JS. PMID: 9116993.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    207. Comparison of two methods of collecting induced sputum in asthmatic subjects. Eur Respir J. 1996 Dec; 9(12):2448-53. Gershman NH, Wong HH, Liu JT, Mahlmeister MJ, Fahy JV. PMID: 8980952.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    208. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. N Engl J Med. 1996 Sep 19; 335(12):841-7. Drazen JM, Israel E, Boushey HA, Chinchilli VM, Fahy JV, Fish JE, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Sorkness C, Szefler SJ. PMID: 8778601.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCTClinical Trials
    209. High-resolution computed tomography of airway changes after induced bronchoconstriction and bronchodilation in asthmatic volunteers. Acad Radiol. 1996 May; 3(5):389-94. Kee ST, Fahy JV, Chen DR, Gamsu G. PMID: 8796690.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    210. Controversies involving inhaled beta-agonists and inhaled corticosteroids in the treatment of asthma. Clin Chest Med. 1995 Dec; 16(4):715-33. Fahy JV, Boushey HA. PMID: 8565410.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    211. Basic mechanisms of asthma. Environ Health Perspect. 1995 Sep; 103 Suppl 6:229-33. Boushey HA, Fahy JV. PMID: 8549478; PMCID: PMC1518922.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    212. Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects. Am J Respir Crit Care Med. 1995 Sep; 152(3):879-84. Fahy JV, Wong HH, Geppetti P, Reis JM, Harris SC, Maclean DB, Nadel JA, Boushey HA. PMID: 7663799.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    213. Analysis of induced sputum after air and ozone exposures in healthy subjects. Environ Res. 1995 Aug; 70(2):77-83. Fahy JV, Wong HH, Liu JT, Boushey HA. PMID: 8674483.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    214. Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med. 1995 Jul; 152(1):53-8. Fahy JV, Wong H, Liu J, Boushey HA. PMID: 7599862.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    215. Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol. 1995 Apr; 95(4):843-52. Fahy JV, Kim KW, Liu J, Boushey HA. PMID: 7722165.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansCells
    216. Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors. Eur Respir J. 1995 Jan; 8(1):10-4. Schuster A, Fahy JV, Ueki I, Nadel JA. PMID: 7744174.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    217. Chronic pulmonary disorders in sickle cell disease: findings at thin-section CT. Radiology. 1994 Dec; 193(3):807-11. Aquino SL, Gamsu G, Fahy JV, Claster S, Embury SH, Mentzer WC, Vichinsky EP. PMID: 7972829.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    218. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol. 1994 Nov; 94(5):861-9. Claman DM, Boushey HA, Liu J, Wong H, Fahy JV. PMID: 7963155.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsCTClinical Trials
    219. Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: a method for studying allergic airway inflammation. J Allergy Clin Immunol. 1994 Jun; 93(6):1031-9. Fahy JV, Liu J, Wong H, Boushey HA. PMID: 8006308.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    220. Use of mucin antibodies and cDNA probes to quantify hypersecretion in vivo in human airways. Am J Respir Cell Mol Biol. 1994 May; 10(5):538-45. Steiger D, Fahy J, Boushey H, Finkbeiner WE, Basbaum C. PMID: 8179917.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    221. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis. 1993 May; 147(5):1126-31. Fahy JV, Liu J, Wong H, Boushey HA. PMID: 8484620.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    222. Markers of mucus secretion and DNA levels in induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis. 1993 May; 147(5):1132-7. Fahy JV, Steiger DJ, Liu J, Basbaum CB, Finkbeiner WE, Boushey HA. PMID: 8484621.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    223. Lack of effect of prophylactic aerosolized pentamidine on the detection of Pneumocystis carinii in induced sputum or bronchoalveolar lavage specimens. Arch Pathol Lab Med. 1993 May; 117(5):493-6. Ng VL, Geaghan SM, Leoung G, Shiboski S, Fahy J, Schnapp L, Yajko DM, Hopewell PC, Hadley WK. PMID: 8489338.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    224. Disappearance of eosinophils from bronchoalveolar lavage fluid after patient education and high-dose inhaled corticosteroids: a case report. Heart Lung. 1993 May-Jun; 22(3):235-8. Janson-Bjerklie S, Fahy J, Geaghan S, Golden J. PMID: 8491659.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    225. Chronic eosinophilic pneumonia. A long-term follow-up of 12 patients. Chest. 1993 Jan; 103(1):162-5. Naughton M, Fahy J, FitzGerald MX. PMID: 8031327.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    226. Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases. Am Rev Respir Dis. 1992 Dec; 146(6):1430-3. Fahy JV, Schuster A, Ueki I, Boushey HA, Nadel JA. PMID: 1280928.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    227. Effect of aerosolized pentamidine prophylaxis on the clinical severity and diagnosis of Pneumocystis carinii pneumonia. Am Rev Respir Dis. 1992 Oct; 146(4):844-8. Fahy JV, Chin DP, Schnapp LM, Steiger DJ, Schaumberg TH, Geaghan SM, Klein JS, Hopewell PC. PMID: 1416408.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    228. Toxoplasma gondii pneumonitis in patients infected with the human immunodeficiency virus. Arch Intern Med. 1992 May; 152(5):1073-7. Schnapp LM, Geaghan SM, Campagna A, Fahy J, Steiger D, Ng V, Hadley WK, Hopewell PC, Stansell JD. PMID: 1304722.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    229. Aminoglycoside induced ototoxicity in patients with cystic fibrosis. Ir J Med Sci. 1991 Jun; 160(6):173-5. Mulherin D, Fahy J, Grant W, Keogan M, Kavanagh B, FitzGerald M. PMID: 1752740.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    230. "Slurry lung": a report of three cases. Thorax. 1991 May; 46(5):394-5. Fahy JV, Walley T, Gibney RT, McCabe M, FitzGerald MX. PMID: 2068701; PMCID: PMC1020977.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    231. A chest radiograph scoring system in adult cystic fibrosis: correlation with pulmonary function. Clin Radiol. 1991 May; 43(5):308-10. O'Laoide RM, Fahy J, Coffey M, Ward K, Malone D, Fitzgerald MX, Masterson J. PMID: 2036754.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    232. Bacteraemia and fungaemia in adults with cystic fibrosis. J Infect. 1991 May; 22(3):241-5. Fahy JV, Keoghan MT, Crummy EJ, FitzGerald MX. PMID: 1906505.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    233. Haemopericardium and cardiac tamponade complicating pulmonary lymphangioleiomyomatosis. Thorax. 1991 Mar; 46(3):222. Fahy J, Toner M, O'Sullivan J, FitzGerald MX. PMID: 2028440; PMCID: PMC463055.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    With one click, see people who:

    Mentor Faculty

    Run Clinical Trials

    Work in Global Health Equity

    Offer Student Projects

    See more options in the Advanced Search tab

    John's Networks
    Concepts (665)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (82)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB04.

    Copyright © The Regents of the University of California.