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    John Forsayeth

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentNeurological Surgery
    Address1855 Folsom Street, MCB
    San Francisco CA 94103
    Phone415-902-4076
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Hadaczek P, Stanek L, Ciesielska A, Sudhakar V, Samaranch L, Pivirotto P, Bringas J, O'Riordan C, Mastis B, San Sebastian W, Forsayeth J, Cheng SH, Bankiewicz KS, Shihabuddin LS. Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease. Mol Ther Methods Clin Dev. 2016; 3:16037. PMID: 27408903.
        View in: PubMed
      2. Green F, Samaranch L, Zhang HS, Manning-Bog A, Meyer K, Forsayeth J, Bankiewicz KS. Axonal transport of AAV9 in nonhuman primate brain. Gene Ther. 2016 Jun; 23(6):520-6. PMID: 26953486.
        View in: PubMed
      3. Samaranch L, Bringas J, Pivirotto P, Sebastian WS, Forsayeth J, Bankiewicz K. Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates. Hum Gene Ther Methods. 2016 Feb; 27(1):13-6. PMID: 26757202.
        View in: PubMed
      4. Seo JW, Ang J, Mahakian LM, Tam S, Fite B, Ingham ES, Beyer J, Forsayeth J, Bankiewicz KS, Xu T, Ferrara KW. Self-assembled 20-nm (64)Cu-micelles enhance accumulation in rat glioblastoma. J Control Release. 2015 Dec 28; 220(Pt A):51-60. PMID: 26437259.
        View in: PubMed
      5. Samaranch L, Hadaczek P, Kells AP, Bringas JR, Stockinger D, San Sebastian W, Macayan M, Samineni S, Pivirotto P, Forsayeth J, Bankiewicz KS. Slow AAV2 clearance from the brain of nonhuman primates and anti-capsid immune response. Gene Ther. 2016 Apr; 23(4):393-8. PMID: 26510688.
        View in: PubMed
      6. Ciesielska A, Sharma N, Beyer J, Forsayeth J, Bankiewicz K. Carbidopa-based modulation of the functional effect of the AAV2-hAADC gene therapy in 6-OHDA lesioned rats. PLoS One. 2015; 10(4):e0122708. PMID: 25860990; PMCID: PMC4393141.
      7. Forsayeth J, Bankiewicz KS. Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies. Mol Ther. 2015 Apr; 23(4):612. PMID: 25849423; PMCID: PMC4395790 [Available on 04/01/16].
      8. Hadaczek P, Wu G, Sharma N, Ciesielska A, Bankiewicz K, Davidow AL, Lu ZH, Forsayeth J, Ledeen RW. GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model. Exp Neurol. 2015 Jan; 263:177-89. PMID: 25448159.
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      9. Yang X, Saito R, Nakamura T, Zhang R, Sonoda Y, Kumabe T, Forsayeth J, Bankiewicz K, Tominaga T. Peri-tumoral leakage during intra-tumoral convection-enhanced delivery has implications for efficacy of peri-tumoral infusion before removal of tumor. Drug Deliv. 2016 Mar; 23(3):781-6. PMID: 24865286.
        View in: PubMed
      10. Barak S, Wang J, Ahmadiantehrani S, Ben Hamida S, Kells AP, Forsayeth J, Bankiewicz KS, Ron D. Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse. Addict Biol. 2015 Jul; 20(4):629-42. PMID: 24801661.
        View in: PubMed
      11. Salegio EA, Streeter H, Dube N, Hadaczek P, Samaranch L, Kells AP, San Sebastian W, Zhai Y, Bringas J, Xu T, Forsayeth J, Bankiewicz KS. Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy. Front Neuroanat. 2014; 8:9. PMID: 24672434; PMCID: PMC3956368.
      12. Noble CO, Krauze MT, Drummond DC, Forsayeth J, Hayes ME, Beyer J, Hadaczek P, Berger MS, Kirpotin DB, Bankiewicz KS, Park JW. Pharmacokinetics, tumor accumulation and antitumor activity of nanoliposomal irinotecan following systemic treatment of intracranial tumors. Nanomedicine (Lond). 2014 Jul; 9(14):2099-108. PMID: 24494810.
        View in: PubMed
      13. Samaranch L, San Sebastian W, Kells AP, Salegio EA, Heller G, Bringas JR, Pivirotto P, DeArmond S, Forsayeth J, Bankiewicz KS. AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol Ther. 2014 Feb; 22(2):329-37. PMID: 24419081; PMCID: PMC3918916.
      14. Dube N, Shu JY, Dong H, Seo JW, Ingham E, Kheirolomoom A, Chen PY, Forsayeth J, Bankiewicz K, Ferrara KW, Xu T. Evaluation of doxorubicin-loaded 3-helix micelles as nanocarriers. Biomacromolecules. 2013 Oct 14; 14(10):3697-705. PMID: 24050265; PMCID: PMC3923314.
      15. San Sebastian W, Samaranch L, Heller G, Kells AP, Bringas J, Pivirotto P, Forsayeth J, Bankiewicz KS. Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain. Gene Ther. 2013 Dec; 20(12):1178-83. PMID: 24067867; PMCID: PMC3855617.
      16. San Sebastian W, Samaranch L, Kells AP, Forsayeth J, Bankiewicz KS. Gene therapy for misfolding protein diseases of the central nervous system. Neurotherapeutics. 2013 Jul; 10(3):498-510. PMID: 23700209; PMCID: PMC3701766.
      17. Yin D, Zhai Y, Gruber HE, Ibanez CE, Robbins JM, Kells AP, Kasahara N, Forsayeth J, Jolly DJ, Bankiewicz KS. Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors in a rodent brain tumor model. Cancer Gene Ther. 2013 Jun; 20(6):336-41. PMID: 23703472; PMCID: PMC3733370.
      18. Samaranch L, Salegio EA, San Sebastian W, Kells AP, Bringas JR, Forsayeth J, Bankiewicz KS. Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates. Hum Gene Ther. 2013 May; 24(5):526-32. PMID: 23517473; PMCID: PMC3655626.
      19. Chen PY, Ozawa T, Drummond DC, Kalra A, Fitzgerald JB, Kirpotin DB, Wei KC, Butowski N, Prados MD, Berger MS, Forsayeth JR, Bankiewicz K, James CD. Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts. Neuro Oncol. 2013 Feb; 15(2):189-97. PMID: 23262509; PMCID: PMC3548589.
      20. Ciesielska A, Hadaczek P, Mittermeyer G, Zhou S, Wright JF, Bankiewicz KS, Forsayeth J. Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses. Mol Ther. 2013 Jan; 21(1):158-66. PMID: 22929660; PMCID: PMC3538301.
      21. Salegio EA, Samaranch L, Jenkins RW, Clarke CJ, Lamarre C, Beyer J, Kells AP, Bringas J, Sebastian WS, Richardson RM, Rosenbluth KH, Hannun YA, Bankiewicz KS, Forsayeth J. Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain. Hum Gene Ther. 2012 Aug; 23(8):891-902. PMID: 22574943; PMCID: PMC3413900.
      22. Bu J, Ashe KM, Bringas J, Marshall J, Dodge JC, Cabrera-Salazar MA, Forsayeth J, Schuchman EH, Bankiewicz KS, Cheng SH, Shihabuddin LS, Passini MA. Merits of combination cortical, subcortical, and cerebellar injections for the treatment of Niemann-Pick disease type A. Mol Ther. 2012 Oct; 20(10):1893-901. PMID: 22828503; PMCID: PMC3464981.
      23. Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS. Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease. Hum Gene Ther. 2012 Apr; 23(4):377-81. PMID: 22424171; PMCID: PMC4530392.
      24. Samaranch L, Salegio EA, San Sebastian W, Kells AP, Foust KD, Bringas JR, Lamarre C, Forsayeth J, Kaspar BK, Bankiewicz KS. Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates. Hum Gene Ther. 2012 Apr; 23(4):382-9. PMID: 22201473; PMCID: PMC3327605.
      25. Salegio EA, Samaranch L, Kells AP, Mittermeyer G, San Sebastian W, Zhou S, Beyer J, Forsayeth J, Bankiewicz KS. Axonal transport of adeno-associated viral vectors is serotype-dependent. Gene Ther. 2013 Mar; 20(3):348-52. PMID: 22418061; PMCID: PMC3381869.
      26. Mendiburu-Eliçabe M, Yin D, Hadaczek P, Zhai Y, Forsayeth J, Bankiewicz KS. Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study. J Neurooncol. 2012 May; 108(1):53-8. PMID: 22350373.
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      27. San Sebastian W, Richardson RM, Kells AP, Lamarre C, Bringas J, Pivirotto P, Salegio EA, Dearmond SJ, Forsayeth J, Bankiewicz KS. Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum. Hum Gene Ther. 2012 Feb; 23(2):210-7. PMID: 22017504; PMCID: PMC3277736.
      28. Hadaczek P, Beyer J, Kells A, Narrow W, Bowers W, Federoff HJ, Forsayeth J, Bankiewicz KS. Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system. PLoS One. 2011; 6(11):e27728. PMID: 22132130; PMCID: PMC3221672.
      29. Salegio EA, Samaranch L, Kells AP, Forsayeth J, Bankiewicz K. Guided delivery of adeno-associated viral vectors into the primate brain. Adv Drug Deliv Rev. 2012 May 15; 64(7):598-604. PMID: 22036906; PMCID: PMC3279613.
      30. Kells AP, Forsayeth J, Bankiewicz KS. Glial-derived neurotrophic factor gene transfer for Parkinson's disease: anterograde distribution of AAV2 vectors in the primate brain. Neurobiol Dis. 2012 Nov; 48(2):228-35. PMID: 22019719; PMCID: PMC3289735.
      31. Forsayeth JR, Bankiewicz KS. AAV9: over the fence and into the woods . . . Mol Ther. 2011 Jun; 19(6):1006-7. PMID: 21629257; PMCID: PMC3129793.
      32. Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease. Mol Ther. 2011 Jun; 19(6):1048-57. PMID: 21343917; PMCID: PMC3129792.
      33. Laganiere J, Kells AP, Lai JT, Guschin D, Paschon DE, Meng X, Fong LK, Yu Q, Rebar EJ, Gregory PD, Bankiewicz KS, Forsayeth J, Zhang HS. An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease. J Neurosci. 2010 Dec 8; 30(49):16469-74. PMID: 21147986.
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      34. Forsayeth J, Bankiewicz KS, Aminoff MJ. Gene therapy for Parkinson's disease: where are we now and where are we going? Expert Rev Neurother. 2010 Dec; 10(12):1839-45. PMID: 21091315.
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      35. Ciesielska A, Mittermeyer G, Hadaczek P, Kells AP, Forsayeth J, Bankiewicz KS. Anterograde axonal transport of AAV2-GDNF in rat basal ganglia. Mol Ther. 2011 May; 19(5):922-7. PMID: 21102559; PMCID: PMC3098627.
      36. Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS. Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease. Neurosurgery. 2010 Nov; 67(5):1377-85. PMID: 20871425.
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      37. Salegio EA, Kells AP, Richardson RM, Hadaczek P, Forsayeth J, Bringas J, Sardi SP, Passini MA, Shihabuddin LS, Cheng SH, Fiandaca MS, Bankiewicz KS. Magnetic resonance imaging-guided delivery of adeno-associated virus type 2 to the primate brain for the treatment of lysosomal storage disorders. Hum Gene Ther. 2010 Sep; 21(9):1093-103. PMID: 20408734; PMCID: PMC2936496.
      38. Yin D, Richardson RM, Fiandaca MS, Bringas J, Forsayeth J, Berger MS, Bankiewicz KS. Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics. J Neurosurg. 2010 Aug; 113(2):240-8. PMID: 20367078.
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      39. Kells AP, Eberling J, Su X, Pivirotto P, Bringas J, Hadaczek P, Narrow WC, Bowers WJ, Federoff HJ, Forsayeth J, Bankiewicz KS. Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. J Neurosci. 2010 Jul 14; 30(28):9567-77. PMID: 20631185; PMCID: PMC2914692.
      40. Su X, Kells AP, Salegio EA, Salegio EA, Richardson RM, Hadaczek P, Beyer J, Bringas J, Pivirotto P, Forsayeth J, Bankiewicz KS. Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors. Mol Ther. 2010 Aug; 18(8):1490-5. PMID: 20551915; PMCID: PMC2927064.
      41. Hadaczek P, Eberling JL, Pivirotto P, Bringas J, Forsayeth J, Bankiewicz KS. Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC. Mol Ther. 2010 Aug; 18(8):1458-61. PMID: 20531394; PMCID: PMC2927057.
      42. Dickinson PJ, LeCouteur RA, Higgins RJ, Bringas JR, Larson RF, Yamashita Y, Krauze MT, Forsayeth J, Noble CO, Drummond DC, Kirpotin DB, Park JW, Berger MS, Bankiewicz KS. Canine spontaneous glioma: a translational model system for convection-enhanced delivery. Neuro Oncol. 2010 Sep; 12(9):928-40. PMID: 20488958; PMCID: PMC2940703.
      43. Hadaczek P, Johnston L, Forsayeth J, Bankiewicz KS. Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain. Neuropharmacology. 2010 Jun; 58(7):1114-21. PMID: 20153340; PMCID: PMC2849906.
      44. Gimenez F, Krauze MT, Valles F, Hadaczek P, Bringas J, Sharma N, Forsayeth J, Bankiewicz KS. Image-guided convection-enhanced delivery of GDNF protein into monkey putamen. Neuroimage. 2011 Jan; 54 Suppl 1:S189-95. PMID: 20080195.
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      45. Yin D, Forsayeth J, Bankiewicz KS. Optimized cannula design and placement for convection-enhanced delivery in rat striatum. J Neurosci Methods. 2010 Mar 15; 187(1):46-51. PMID: 20026357; PMCID: PMC2865230.
      46. Su X, Kells AP, Huang EJ, Lee HS, Hadaczek P, Beyer J, Bringas J, Pivirotto P, Penticuff J, Eberling J, Federoff HJ, Forsayeth J, Bankiewicz KS. Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys. Hum Gene Ther. 2009 Dec; 20(12):1627-40. PMID: 19671001; PMCID: PMC2861959.
      47. Yin D, Valles FE, Fiandaca MS, Bringas J, Gimenez F, Berger MS, Forsayeth J, Bankiewicz KS. Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates. Neuroimage. 2011 Jan; 54 Suppl 1:S196-203. PMID: 19761848; PMCID: PMC2895968.
      48. Valles F, Fiandaca MS, Bringas J, Dickinson P, LeCouteur R, Higgins R, Berger M, Forsayeth J, Bankiewicz KS. Anatomic compression caused by high-volume convection-enhanced delivery to the brain. Neurosurgery. 2009 Sep; 65(3):579-85; discussion 585-6. PMID: 19687704; PMCID: PMC2745991.
      49. Johnston LC, Eberling J, Pivirotto P, Hadaczek P, Federoff HJ, Forsayeth J, Bankiewicz KS. Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys. Hum Gene Ther. 2009 May; 20(5):497-510. PMID: 19203243; PMCID: PMC2767387.
      50. Eberling JL, Kells AP, Pivirotto P, Beyer J, Bringas J, Federoff HJ, Forsayeth J, Bankiewicz KS. Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys. Hum Gene Ther. 2009 May; 20(5):511-8. PMID: 19254173; PMCID: PMC2725183.
      51. Richardson RM, Varenika V, Forsayeth JR, Bankiewicz KS. Future applications: gene therapy. Neurosurg Clin N Am. 2009 Apr; 20(2):205-10. PMID: 19555883; PMCID: PMC3030700.
      52. Hadaczek P, Forsayeth J, Mirek H, Munson K, Bringas J, Pivirotto P, McBride JL, Davidson BL, Bankiewicz KS. Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response. Hum Gene Ther. 2009 Mar; 20(3):225-37. PMID: 19292604; PMCID: PMC2730589.
      53. Kells AP, Hadaczek P, Yin D, Bringas J, Varenika V, Forsayeth J, Bankiewicz KS. Efficient gene therapy-based method for the delivery of therapeutics to primate cortex. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2407-11. PMID: 19193857; PMCID: PMC2650169.
      54. Krauze MT, Forsayeth J, Yin D, Bankiewicz KS. Convection-enhanced delivery of liposomes to primate brain. Methods Enzymol. 2009; 465:349-62. PMID: 19913176.
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      55. Varenika V, Kells AP, Valles F, Hadaczek P, Forsayeth J, Bankiewicz KS. Controlled dissemination of AAV vectors in the primate brain. Prog Brain Res. 2009; 175:163-72. PMID: 19660655.
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      56. Fiandaca MS, Varenika V, Eberling J, McKnight T, Bringas J, Pivirotto P, Beyer J, Hadaczek P, Bowers W, Park J, Federoff H, Forsayeth J, Bankiewicz KS. Real-time MR imaging of adeno-associated viral vector delivery to the primate brain. Neuroimage. 2009 Aug; 47 Suppl 2:T27-35. PMID: 19095069; PMCID: PMC2730220.
      57. Yin D, Valles FE, Fiandaca MS, Forsayeth J, Larson P, Starr P, Bankiewicz KS. Striatal volume differences between non-human and human primates. J Neurosci Methods. 2009 Jan 30; 176(2):200-5. PMID: 18809434; PMCID: PMC2662364.
      58. Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. Engineering GPCR signaling pathways with RASSLs. Nat Methods. 2008 Aug; 5(8):673-8. PMID: 18668035; PMCID: PMC2703467.
      59. Johnston LC, Su X, Maguire-Zeiss K, Horovitz K, Ankoudinova I, Guschin D, Hadaczek P, Federoff HJ, Bankiewicz K, Forsayeth J. Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease. Mol Ther. 2008 Aug; 16(8):1392-9. PMID: 18545225; PMCID: PMC2725180.
      60. Fiandaca MS, Forsayeth JR, Dickinson PJ, Bankiewicz KS. Image-guided convection-enhanced delivery platform in the treatment of neurological diseases. Neurotherapeutics. 2008 Jan; 5(1):123-7. PMID: 18164491; PMCID: PMC2719019.
      61. Krauze MT, Vandenberg SR, Yamashita Y, Saito R, Forsayeth J, Noble C, Park J, Bankiewicz KS. Safety of real-time convection-enhanced delivery of liposomes to primate brain: a long-term retrospective. Exp Neurol. 2008 Apr; 210(2):638-44. PMID: 18295759; PMCID: PMC2362104.
      62. Fiandaca M, Forsayeth J, Bankiewicz K. Current status of gene therapy trials for Parkinson's disease. Exp Neurol. 2008 Jan; 209(1):51-7. PMID: 17920059.
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      63. Krauze MT, Noble CO, Kawaguchi T, Drummond D, Kirpotin DB, Yamashita Y, Kullberg E, Forsayeth J, Park JW, Bankiewicz KS. Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts. Neuro Oncol. 2007 Oct; 9(4):393-403. PMID: 17652269; PMCID: PMC1994096.
      64. Krauze MT, Forsayeth J, Park JW, Bankiewicz KS. Real-time imaging and quantification of brain delivery of liposomes. Pharm Res. 2006 Nov; 23(11):2493-504. PMID: 16972184.
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      65. Bankiewicz KS, Forsayeth J, Eberling JL, Sanchez-Pernaute R, Pivirotto P, Bringas J, Herscovitch P, Carson RE, Eckelman W, Reutter B, Cunningham J. Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. Mol Ther. 2006 Oct; 14(4):564-70. PMID: 16829205.
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      66. Forsayeth JR, Eberling JL, Sanftner LM, Zhen Z, Pivirotto P, Bringas J, Cunningham J, Bankiewicz KS. A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys. Mol Ther. 2006 Oct; 14(4):571-7. PMID: 16781894; PMCID: PMC2725179.
      67. Daadi MM, Pivirotto P, Bringas J, Cunningham J, Forsayeth J, Eberling J, Bankiewicz KS. Distribution of AAV2-hAADC-transduced cells after 3 years in Parkinsonian monkeys. Neuroreport. 2006 Feb 6; 17(2):201-4. PMID: 16407771.
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      68. Bankiewicz KS, Daadi M, Pivirotto P, Bringas J, Sanftner L, Cunningham J, Forsayeth JR, Eberling JL. Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys. Exp Neurol. 2006 Feb; 197(2):363-72. PMID: 16337943; PMCID: PMC2766604.
      69. Krauze MT, Mcknight TR, Yamashita Y, Bringas J, Noble CO, Saito R, Geletneky K, Forsayeth J, Berger MS, Jackson P, Park JW, Bankiewicz KS. Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging. Brain Res Brain Res Protoc. 2005 Dec; 16(1-3):20-6. PMID: 16181805.
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      70. Sanftner LM, Rivera VM, Suzuki BM, Feng L, Berk L, Zhou S, Forsayeth JR, Clackson T, Cunningham J. Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats. Mol Ther. 2006 Jan; 13(1):167-74. PMID: 16126007.
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      71. Shumilla JA, Samuels I, Johnson KW, Forsayeth JR. Systemic administration of propentofylline does not attenuate morphine tolerance in non-injured rodents. Neurosci Lett. 2005 Aug 26; 384(3):344-8. PMID: 15953678.
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      72. Krauze MT, Saito R, Noble C, Bringas J, Forsayeth J, McKnight TR, Park J, Bankiewicz KS. Effects of the perivascular space on convection-enhanced delivery of liposomes in primate putamen. Exp Neurol. 2005 Nov; 196(1):104-11. PMID: 16109410.
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      73. Sanftner LM, Sommer JM, Suzuki BM, Smith PH, Vijay S, Vargas JA, Forsayeth JR, Cunningham J, Bankiewicz KS, Kao H, Bernal J, Pierce GF, Johnson KW. AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters. Exp Neurol. 2005 Aug; 194(2):476-83. PMID: 16022872; PMCID: PMC3816113.
      74. Doroudchi MM, Liauw J, Heaton K, Zhen Z, Forsayeth JR. Adeno-associated virus-mediated gene transfer of human aromatic L-amino acid decarboxylase protects mixed striatal primary cultures from L-DOPA toxicity. J Neurochem. 2005 May; 93(3):634-40. PMID: 15836622.
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      75. Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci. 2005 Apr; 21(8):2136-48. PMID: 15869510.
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      76. Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005; 1:9. PMID: 15813997; PMCID: PMC1079940.
      77. Sanftner LM, Suzuki BM, Doroudchi MM, Feng L, McClelland A, Forsayeth JR, Cunningham J. Striatal delivery of rAAV-hAADC to rats with preexisting immunity to AAV. Mol Ther. 2004 Mar; 9(3):403-9. PMID: 15006607.
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      78. Marangi PA, Forsayeth JR, Mittaud P, Erb-Vögtli S, Blake DJ, Moransard M, Sander A, Fuhrer C. Acetylcholine receptors are required for agrin-induced clustering of postsynaptic proteins. EMBO J. 2001 Dec 17; 20(24):7060-73. PMID: 11742983; PMCID: PMC125801.
      79. Truong A, Xing X, Forsayeth JR, Dwoskin LP, Crooks PA, Cohen BN. Pharmacological differences between immunoisolated native brain and heterologously expressed rat alpha4beta2 nicotinic receptors. Brain Res Mol Brain Res. 2001 Nov 30; 96(1-2):68-76. PMID: 11731010.
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      80. Fitzgerald J, Kennedy D, Viseshakul N, Cohen BN, Mattick J, Bateman JF, Forsayeth JR. UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein. Brain Res. 2000 Sep 15; 877(1):110-23. PMID: 10980252.
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      81. Gray AT, Zhao BB, Kindler CH, Winegar BD, Mazurek MJ, Xu J, Chavez RA, Forsayeth JR, Yost CS. Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5. Anesthesiology. 2000 Jun; 92(6):1722-30. PMID: 10839924.
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      82. Sweileh W, Wenberg K, Xu J, Forsayeth J, Hardy S, Loring RH. Multistep expression and assembly of neuronal nicotinic receptors is both host-cell- and receptor-subtype-dependent. Brain Res Mol Brain Res. 2000 Feb 22; 75(2):293-302. PMID: 10686351.
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      83. Shafaee N, Houng M, Truong A, Viseshakul N, Figl A, Sandhu S, Forsayeth JR, Dwoskin LP, Crooks PA, Cohen BN. Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors. Br J Pharmacol. 1999 Nov; 128(6):1291-9. PMID: 10578144; PMCID: PMC1571746.
      84. Wang N, Verna L, Hardy S, Forsayeth J, Zhu Y, Stemerman MB. Adenovirus-mediated overexpression of c-Jun and c-Fos induces intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human endothelial cells. Arterioscler Thromb Vasc Biol. 1999 Sep; 19(9):2078-84. PMID: 10479648.
        View in: PubMed
      85. Chavez RA, Gray AT, Zhao BB, Kindler CH, Mazurek MJ, Mehta Y, Forsayeth JR, Yost CS. TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family. J Biol Chem. 1999 Mar 19; 274(12):7887-92. PMID: 10075682.
        View in: PubMed
      86. Figl A, Viseshakul N, Shafaee N, Forsayeth J, Cohen BN. Two mutations linked to nocturnal frontal lobe epilepsy cause use-dependent potentiation of the nicotinic ACh response. J Physiol. 1998 Dec 15; 513 ( Pt 3):655-70. PMID: 9824708; PMCID: PMC2231326.
      87. Gray AT, Winegar BD, Leonoudakis DJ, Forsayeth JR, Yost CS. TOK1 is a volatile anesthetic stimulated K+ channel. Anesthesiology. 1998 Apr; 88(4):1076-84. PMID: 9579518.
        View in: PubMed
      88. Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, Chavez RA, Forsayeth JR, Yost CS. An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum. J Neurosci. 1998 Feb 1; 18(3):868-77. PMID: 9437008.
        View in: PubMed
      89. Eilers H, Schaeffer E, Bickler PE, Forsayeth JR. Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase C-dependent mechanism. Mol Pharmacol. 1997 Dec; 52(6):1105-12. PMID: 9415721.
        View in: PubMed
      90. Xia H, Fitzgerald J, Bredt DS, Forsayeth JR. Detection of mycoplasma infection of mammalian cells. Biotechniques. 1997 May; 22(5):934-6. PMID: 9149878.
        View in: PubMed
      91. Forsayeth JR, Kobrin E. Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor. J Neurosci. 1997 Mar 1; 17(5):1531-8. PMID: 9030613.
        View in: PubMed
      92. Gorman S, Viseshakul N, Cohen B, Hardy S, Grant GA, Yost CS, Forsayeth JR. A recombinant adenovirus that directs secretion of biologically active kappa-bungarotoxin from mammalian cells. Brain Res Mol Brain Res. 1997 Feb; 44(1):143-6. PMID: 9030709.
        View in: PubMed
      93. Winegar BD, Owen DF, Yost CS, Forsayeth JR, Mayeri E. Volatile general anesthetics produce hyperpolarization of Aplysia neurons by activation of a discrete population of baseline potassium channels. Anesthesiology. 1996 Oct; 85(4):889-900. PMID: 8873561.
        View in: PubMed
      94. Sawa T, Miyazaki H, Pittet JF, Widdicombe JH, Gropper MA, Hashimoto S, Conrad DJ, Folkesson HG, Debs R, Forsayeth JR, Fox B, Wiener-Kronish JP. Intraluminal water increases expression of plasmid DNA in rat lung. Hum Gene Ther. 1996 May 20; 7(8):933-41. PMID: 8727507.
        View in: PubMed
      95. Forsayeth JR, Garcia PD. Adenovirus-mediated transfection of cultured cells. Biotechniques. 1994 Aug; 17(2):354-6, 357-8. PMID: 7980940.
        View in: PubMed
      96. Forsayeth JR, Gu Y, Hall ZW. BiP forms stable complexes with unassembled subunits of the acetylcholine receptor in transfected COS cells and in C2 muscle cells. J Cell Biol. 1992 May; 117(4):841-7. PMID: 1577860; PMCID: PMC2289465.
      97. Gu Y, Forsayeth JR, Verrall S, Yu XM, Hall ZW. Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells. J Cell Biol. 1991 Aug; 114(4):799-807. PMID: 1869588; PMCID: PMC2289901.
      98. Forsayeth JR, Franco A, Rossi AB, Lansman JB, Hall ZW. Expression of functional mouse muscle acetylcholine receptors in Chinese hamster ovary cells. J Neurosci. 1990 Aug; 10(8):2771-9. PMID: 2388086.
        View in: PubMed
      99. Gu Y, Franco A, Gardner PD, Lansman JB, Forsayeth JR, Hall ZW. Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells. Neuron. 1990 Aug; 5(2):147-57. PMID: 2383398.
        View in: PubMed
      100. LaRochelle WJ, Ralston E, Forsayeth JR, Froehner SC, Hall ZW. Clusters of 43-kDa protein are absent from genetic variants of C2 muscle cells with reduced acetylcholine receptor expression. Dev Biol. 1989 Mar; 132(1):130-8. PMID: 2645181.
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      101. Gu JL, Goldfine ID, Forsayeth JR, De Meyts P. Reversal of insulin-induced negative cooperativity by monoclonal antibodies that stabilize the slowly dissociating ("Ksuper") state of the insulin receptor. Biochem Biophys Res Commun. 1988 Jan 29; 150(2):694-701. PMID: 3277631.
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      102. Forsayeth JR, Caro JF, Sinha MK, Maddux BA, Goldfine ID. Monoclonal antibodies to the human insulin receptor that activate glucose transport but not insulin receptor kinase activity. Proc Natl Acad Sci U S A. 1987 May; 84(10):3448-51. PMID: 3033648; PMCID: PMC304888.
      103. Forsayeth JR, Montemurro A, Maddux BA, DePirro R, Goldfine ID. Effect of monoclonal antibodies on human insulin receptor autophosphorylation, negative cooperativity, and down-regulation. J Biol Chem. 1987 Mar 25; 262(9):4134-40. PMID: 2435731.
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      104. Forsayeth J, Maddux B, Goldfine ID. Biosynthesis and processing of the human insulin receptor. Diabetes. 1986 Jul; 35(7):837-46. PMID: 3721067.
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      105. Forsayeth JR, Gould MK. Inhibition of insulin-stimulated xylose uptake in rat soleus muscle by cycloheximide. Diabetologia. 1983 Nov; 25(5):429-32. PMID: 6360781.
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      106. Forsayeth J, Gould MK. Stimulatory and inhibitory effects of hydrogen peroxide, diamide and vitamin K-5 on sugar transport in rat soleus muscle. Biochim Biophys Acta. 1983 Sep 13; 759(3):184-91. PMID: 6882798.
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      107. Forsayeth JR, Gould MK. Inhibition of insulin-stimulated xylose uptake in denervated rat soleus muscle: a post-receptor effect. Diabetologia. 1982 Dec; 23(6):511-6. PMID: 6818081.
        View in: PubMed
      108. Forsayeth J, Gould MK. Effects of hyperosmolarity on basal and insulin-stimulated muscle sugar transport. Am J Physiol. 1981 Mar; 240(3):E263-7. PMID: 6782890.
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