John Watson, PhD
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| Title | Professor |
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| School | UCSF School of Medicine |
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| Department | School of Medicine Dean's Office |
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| Address | |
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Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Plemenitas A, Watson JA. Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol. Eur J Biochem. 1999 Dec; 266(2):317-26.
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Giron MD, Havel CM, Watson JA. Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14):6398-402.
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Li R, Havel C, Watson JA, Murray AW. The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. Nature. 1993 Nov 4; 366(6450):82-4.
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Giron MD, Havel CM, Watson JA. Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Arch Biochem Biophys. 1993 Apr; 302(1):265-71.
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Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute mevalonic acid utilization and 3-hydroxy-3-methylglutaryl-coenzyme A reductase modulation. Arch Biochem Biophys. 1992 Oct; 298(1):204-10.
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Havel CM, Fisher P, Watson JA. Isopentenoid synthesis in embryonic Drosophila cells: prenylated protein profile and prenyl group usage. Arch Biochem Biophys. 1992 Jun; 295(2):410-20.
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Glenn JS, Watson JA, Havel CM, White JM. Identification of a prenylation site in delta virus large antigen. Science. 1992 May 29; 256(5061):1331-3.
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Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. Arch Biochem Biophys. 1992 May 1; 294(2):639-46.
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Plemenitas A, Havel CM, Watson JA. Sterol-mediated regulation of mevalonic acid synthesis. Accumulation of 4-carboxysterols as the predominant sterols synthesized in a Chinese hamster ovary cell cholesterol auxotroph (mutant 215). J Biol Chem. 1990 Oct 5; 265(28):17012-7.
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Erickson SK, Cooper AD, Barnard GF, Havel CM, Watson JA, Feingold KR, Moser AH, Hughes-Fulford M, Siperstein MD. Regulation of cholesterol metabolism in a slow-growing hepatoma in vivo. Biochim Biophys Acta. 1988 May 22; 960(2):131-8.
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Gonzalez-Pacanowska D, Arison B, Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. J Biol Chem. 1988 Jan 25; 263(3):1301-6.
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Havel C, Rector ER, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. J Biol Chem. 1986 Aug 5; 261(22):10150-6.
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Cabrera JA, Bolds J, Shields PE, Havel CM, Watson JA. Isoprenoid synthesis in Halobacterium halobium. Modulation of 3-hydroxy-3-methylglutaryl coenzyme a concentration in response to mevalonate availability. J Biol Chem. 1986 Mar 15; 261(8):3578-83.
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Watson JA, Havel CM, Lobos DV, Baker FC, Morrow CJ. Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. J Biol Chem. 1985 Nov 15; 260(26):14083-91.
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Brown K, Havel CM, Watson JA. Isoprene synthesis in isolated embryonic Drosophila cells. II. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. J Biol Chem. 1983 Jul 10; 258(13):8512-8.
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Silberkang M, Havel CM, Friend DS, McCarthy BJ, Watson JA. Isoprene synthesis in isolated embryonic Drosophila cells. I. Sterol-deficient eukaryotic cells. J Biol Chem. 1983 Jul 10; 258(13):8503-11.
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Havel C, Hansbury E, Scallen TJ, Watson JA. Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation. J Biol Chem. 1979 Oct 10; 254(19):9573-82.
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Beirne OR, Heller R, Watson JA. Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells. J Biol Chem. 1977 Feb 10; 252(3):950-4.
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Beirne OR, Watson JA. Comparison of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma cells grown in vivo and in vitro. Proc Natl Acad Sci U S A. 1976 Aug; 73(8):2735-9.
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Bell JJ, Sargeant TE, Watson JA. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l. J Biol Chem. 1976 Mar 25; 251(6):1745-58.
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Kirsten ES, Watson JA. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins. J Biol Chem. 1974 Oct 10; 249(19):6104-9.
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