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    John Watson, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentSchool of Medicine Dean's Office
    Address

       Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Plemenitas A, Watson JA. Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol. Eur J Biochem. 1999 Dec; 266(2):317-26.
        View in: PubMed
      2. Giron MD, Havel CM, Watson JA. Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14):6398-402.
        View in: PubMed
      3. Li R, Havel C, Watson JA, Murray AW. The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. Nature. 1993 Nov 4; 366(6450):82-4.
        View in: PubMed
      4. Giron MD, Havel CM, Watson JA. Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Arch Biochem Biophys. 1993 Apr; 302(1):265-71.
        View in: PubMed
      5. Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute mevalonic acid utilization and 3-hydroxy-3-methylglutaryl-coenzyme A reductase modulation. Arch Biochem Biophys. 1992 Oct; 298(1):204-10.
        View in: PubMed
      6. Havel CM, Fisher P, Watson JA. Isopentenoid synthesis in embryonic Drosophila cells: prenylated protein profile and prenyl group usage. Arch Biochem Biophys. 1992 Jun; 295(2):410-20.
        View in: PubMed
      7. Glenn JS, Watson JA, Havel CM, White JM. Identification of a prenylation site in delta virus large antigen. Science. 1992 May 29; 256(5061):1331-3.
        View in: PubMed
      8. Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. Arch Biochem Biophys. 1992 May 1; 294(2):639-46.
        View in: PubMed
      9. Plemenitas A, Havel CM, Watson JA. Sterol-mediated regulation of mevalonic acid synthesis. Accumulation of 4-carboxysterols as the predominant sterols synthesized in a Chinese hamster ovary cell cholesterol auxotroph (mutant 215). J Biol Chem. 1990 Oct 5; 265(28):17012-7.
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      10. Erickson SK, Cooper AD, Barnard GF, Havel CM, Watson JA, Feingold KR, Moser AH, Hughes-Fulford M, Siperstein MD. Regulation of cholesterol metabolism in a slow-growing hepatoma in vivo. Biochim Biophys Acta. 1988 May 22; 960(2):131-8.
        View in: PubMed
      11. Gonzalez-Pacanowska D, Arison B, Havel CM, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. J Biol Chem. 1988 Jan 25; 263(3):1301-6.
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      12. Havel C, Rector ER, Watson JA. Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. J Biol Chem. 1986 Aug 5; 261(22):10150-6.
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      13. Cabrera JA, Bolds J, Shields PE, Havel CM, Watson JA. Isoprenoid synthesis in Halobacterium halobium. Modulation of 3-hydroxy-3-methylglutaryl coenzyme a concentration in response to mevalonate availability. J Biol Chem. 1986 Mar 15; 261(8):3578-83.
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      14. Watson JA, Havel CM, Lobos DV, Baker FC, Morrow CJ. Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. J Biol Chem. 1985 Nov 15; 260(26):14083-91.
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      15. Brown K, Havel CM, Watson JA. Isoprene synthesis in isolated embryonic Drosophila cells. II. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. J Biol Chem. 1983 Jul 10; 258(13):8512-8.
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      16. Silberkang M, Havel CM, Friend DS, McCarthy BJ, Watson JA. Isoprene synthesis in isolated embryonic Drosophila cells. I. Sterol-deficient eukaryotic cells. J Biol Chem. 1983 Jul 10; 258(13):8503-11.
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      17. Havel C, Hansbury E, Scallen TJ, Watson JA. Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation. J Biol Chem. 1979 Oct 10; 254(19):9573-82.
        View in: PubMed
      18. Beirne OR, Heller R, Watson JA. Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells. J Biol Chem. 1977 Feb 10; 252(3):950-4.
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      19. Beirne OR, Watson JA. Comparison of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma cells grown in vivo and in vitro. Proc Natl Acad Sci U S A. 1976 Aug; 73(8):2735-9.
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      20. Bell JJ, Sargeant TE, Watson JA. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l. J Biol Chem. 1976 Mar 25; 251(6):1745-58.
        View in: PubMed
      21. Kirsten ES, Watson JA. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins. J Biol Chem. 1974 Oct 10; 249(19):6104-9.
        View in: PubMed
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