Jordan Ward

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address600 16th St
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Transcriptional networks controlling molting in C. elegans and B. malayi
    NIH/NIGMS R00GM107345May 1, 2014 - Nov 30, 2019
    Role: Principal Investigator
    Transcriptional networks controlling molting in C. elegans and B. malayi
    NIH/NIGMS K99GM107345May 1, 2014 - Apr 30, 2016
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ratnappan R, Ward JD, Yamamoto KR, Ghazi A. Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. Worm. 2016 Jan-Mar; 5(1):e1151609. PMID: 27073739.
      View in: PubMed
    2. Ward JD. Rendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic Nematodes. Genetics. 2015 Dec; 201(4):1279-94. PMID: 26644478.
      View in: PubMed
    3. Zhang L, Ward JD, Cheng Z, Dernburg AF. The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans. Development. 2015 Dec 15; 142(24):4374-84. PMID: 26552885.
      View in: PubMed
    4. Taylor MR, Špírek M, Chaurasiya KR, Ward JD, Carzaniga R, Yu X, Egelman EH, Collinson LM, Rueda D, Krejci L, Boulton SJ. Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Cell. 2015 Jul 16; 162(2):271-86. PMID: 26186187; PMCID: PMC4518479.
    5. Ward JD. Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. Genetics. 2015 Feb; 199(2):363-77. PMID: 25491644; PMCID: PMC4317648.
    6. Ratnappan R, Amrit FR, Chen SW, Gill H, Holden K, Ward J, Yamamoto KR, Olsen CP, Ghazi A. Germline signals deploy NHR-49 to modulate fatty-acid ß-oxidation and desaturation in somatic tissues of C. elegans. PLoS Genet. 2014 Dec; 10(12):e1004829. PMID: 25474470; PMCID: PMC4256272.
    7. Ward JD, Yamamoto KR, Asahina M. SUMO as a nuclear hormone receptor effector: New insights into combinatorial transcriptional regulation. Worm. 2014; 3:e29317. PMID: 25254154; PMCID: PMC4165532.
    8. Ward JD, Mullaney B, Schiller BJ, He le D, Petnic SE, Couillault C, Pujol N, Bernal TU, Van Gilst MR, Ashrafi K, Ewbank JJ, Yamamoto KR. Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses. PLoS One. 2014; 9(3):e92552. PMID: 24651852; PMCID: PMC3961378.
    9. Ward JD, Bojanala N, Bernal T, Ashrafi K, Asahina M, Yamamoto KR. Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development. PLoS Genet. 2013; 9(12):e1003992. PMID: 24348269; PMCID: PMC3861103.
    10. Dickinson DJ, Ward JD, Reiner DJ, Goldstein B. Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat Methods. 2013 Oct; 10(10):1028-34. PMID: 23995389; PMCID: PMC3905680.
    11. O'Neil NJ, Martin JS, Youds JL, Ward JD, Petalcorin MI, Rose AM, Boulton SJ. Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis. PLoS Genet. 2013; 9(7):e1003582. PMID: 23874209; PMCID: PMC3715453.
    12. Adamo A, Collis SJ, Adelman CA, Silva N, Horejsi Z, Ward JD, Martinez-Perez E, Boulton SJ, La Volpe A. Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell. 2010 Jul 9; 39(1):25-35. PMID: 20598602.
      View in: PubMed
    13. Taubert S, Ward JD, Yamamoto KR. Nuclear hormone receptors in nematodes: evolution and function. Mol Cell Endocrinol. 2011 Mar 1; 334(1-2):49-55. PMID: 20438802; PMCID: PMC3042524.
    14. Youds JL, Mets DG, McIlwraith MJ, Martin JS, Ward JD, ONeil NJ, Rose AM, West SC, Meyer BJ, Boulton SJ. RTEL-1 enforces meiotic crossover interference and homeostasis. Science. 2010 Mar 5; 327(5970):1254-8. PMID: 20203049.
      View in: PubMed
    15. Ward JD, Muzzini DM, Petalcorin MI, Martinez-Perez E, Martin JS, Plevani P, Cassata G, Marini F, Boulton SJ. Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell. 2010 Jan 29; 37(2):259-72. PMID: 20122407.
      View in: PubMed
    16. Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 2008 Oct 17; 135(2):261-71. PMID: 18957201; PMCID: PMC3726190.
    17. Hobson N, Price NL, Ward JD, Raivio TL. Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids. BMC Microbiol. 2008; 8:134. PMID: 18681975; PMCID: PMC2518929.
    18. Goodyer W, Kaitna S, Couteau F, Ward JD, Boulton SJ, Zetka M. HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell. 2008 Feb; 14(2):263-74. PMID: 18267094.
      View in: PubMed
    19. Macritchie DM, Ward JD, Nevesinjac AZ, Raivio TL. Activation of the Cpx envelope stress response down-regulates expression of several locus of enterocyte effacement-encoded genes in enteropathogenic Escherichia coli. Infect Immun. 2008 Apr; 76(4):1465-75. PMID: 18227171; PMCID: PMC2292881.
    20. Adamo A, Montemauri P, Silva N, Ward JD, Boulton SJ, La Volpe A. BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair. EMBO Rep. 2008 Mar; 9(3):287-92. PMID: 18219312; PMCID: PMC2267377.
    21. Youds JL, Barber LJ, Ward JD, Collis SJ, O'Neil NJ, Boulton SJ, Rose AM. DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol. 2008 Mar; 28(5):1470-9. PMID: 18086896; PMCID: PMC2258786.
    22. Ward JD, Barber LJ, Petalcorin MI, Yanowitz J, Boulton SJ. Replication blocking lesions present a unique substrate for homologous recombination. EMBO J. 2007 Jul 25; 26(14):3384-96. PMID: 17611606; PMCID: PMC1933397.
    23. Collis SJ, Barber LJ, Clark AJ, Martin JS, Ward JD, Boulton SJ. HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nat Cell Biol. 2007 Apr; 9(4):391-401. PMID: 17384638.
      View in: PubMed
    24. Collis SJ, Barber LJ, Ward JD, Martin JS, Boulton SJ. C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair. DNA Repair (Amst). 2006 Nov 8; 5(11):1398-406. PMID: 16914393.
      View in: PubMed
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