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    Kazuhito Morioka, MD, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentNeurological Surgery
    Address1001 Potrero Ave
    San Francisco CA 94110
    Phone415-206-4297
    EmailKazuhito.Morioka@ucsf.edu
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      Collapse Biography 
      Collapse Awards and Honors
      33rd Annual symposium of the National Neurotrauma Society2015Student Competition Finalist Presenter
      32th Annual symposium of the National Neurotrauma Society2014Student Competition Finalist Presenter
      Society for Neuroscience2011Special Travel Award
      31st Annual Meeting of the American Society for Bone and Mineral Research2009Plenary Poster
      27th Annual Meeting of the Japanese Society for Bone and Mineral Research2009Young Investigator Award

      Collapse Overview 
      Collapse Overview
      Over the past 10 years, I have worked in clinical orthopaedic surgery from emergency to rehabilitation in spinal disorders and related projects in Japan. During my PhD in bone biology and oncology, I received training in molecular biology techniques and statistical genetics/genomics and translation methodology. My doctoral dissertation investigated the gene expression profiles using cDNA microarray analysis in osteosarcoma samples, identifying the tyrosine kinase orphan receptor with ligand Wnt as a candidate therapeutic target for human osteosarcoma. In my postdoctoral fellow in Japan, I received training in pre-clinical spinal cord injury (SCI) research at the University of Zurich, and took part in a pilot study to evaluate a novel biomarker for the severity of SCI patients at the National Rehabilitation Center, gaining an interest in spinal cord research. In my postdoctoral fellow in US, my current research focuses on the cellular mechanisms of neuronal plasticity and functional recovery following traumatic central nervous system injury at UCSF Brain and Spinal Injury Center. I hope that our fruitful projects might serve as patients for allowing to acquire essential functions again leading to improved quality of life.


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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Okazaki R, Doi T, Hayakawa K, Morioka K, Imamura O, Takishima K, Hamanoue M, Sawada Y, Nagao M, Tanaka S, Ogata T. The crucial role of Erk2 in demyelinating inflammation in the central nervous system. J Neuroinflammation. 2016; 13(1):235. PMID: 27596241; PMCID: PMC5011945.
      2. Hamanoue M, Morioka K, Ohsawa I, Ohsawa K, Kobayashi M, Tsuburaya K, Akasaka Y, Mikami T, Ogata T, Takamatsu K. Cell-permeable p38?MAP kinase promotes migration of adult neural stem/progenitor cells. Sci Rep. 2016; 6:24279. PMID: 27067799.
        View in: PubMed
      3. Hayakawa K, Okazaki R, Morioka K, Nakamura K, Tanaka S, Ogata T. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. J Neurosci Res. 2014 Dec; 92(12):1647-58. PMID: 25044014.
        View in: PubMed
      4. Hayakawa K, Okazaki R, Ishii K, Ueno T, Izawa N, Tanaka Y, Toyooka S, Matsuoka N, Morioka K, Ohori Y, Nakamura K, Akai M, Tobimatsu Y, Hamabe Y, Ogata T. Phosphorylated neurofilament subunit NF-H as a biomarker for evaluating the severity of spinal cord injury patients, a pilot study. Spinal Cord. 2012 Jul; 50(7):493-6. PMID: 22270191.
        View in: PubMed
      5. Ogata T, Ueno T, Hoshikawa S, Ito J, Okazaki R, Hayakawa K, Morioka K, Yamamoto S, Nakamura K, Tanaka S, Akai M. Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage. Neuroscience. 2011 Mar 10; 176:132-41. PMID: 21167918.
        View in: PubMed
      6. Morioka K, Tanikawa C, Ochi K, Daigo Y, Katagiri T, Kawano H, Kawaguchi H, Myoui A, Yoshikawa H, Naka N, Araki N, Kudawara I, Ieguchi M, Nakamura K, Nakamura Y, Matsuda K. Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Sci. 2009 Jul; 100(7):1227-33. PMID: 19486338.
        View in: PubMed
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