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Kazuhito Morioka, MD, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentNeurological Surgery
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-206-4297
EmailKazuhito.Morioka@ucsf.edu
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    Collapse Biography 
    Collapse Awards and Honors
    33rd Annual symposium of the National Neurotrauma Society2015Student Competition Finalist Presenter
    32th Annual symposium of the National Neurotrauma Society2014Student Competition Finalist Presenter
    Wings for Life Spinal Cord Research Foundation2013 - 2015Individual Research Grant
    Society for Neuroscience2011Special Travel Award
    31st Annual Meeting of the American Society for Bone and Mineral Research2009Plenary Poster
    27th Annual Meeting of the Japanese Society for Bone and Mineral Research2009Young Investigator Award

    Collapse Overview 
    Collapse Overview
    Over the past 10 years, I have worked in clinical orthopaedic surgery from emergency to rehabilitation in spinal disorders and related projects in Japan. During my PhD in bone biology and oncology, I received training in molecular biology techniques and statistical genetics/genomics and translation methodology. My doctoral dissertation investigated the gene expression profiles using cDNA microarray analysis in osteosarcoma samples, identifying the tyrosine kinase orphan receptor with ligand Wnt as a candidate therapeutic target for human osteosarcoma. In my postdoctoral fellow in Japan, I received training in pre-clinical spinal cord injury (SCI) research at the University of Zurich, and took part in a pilot study to evaluate a novel biomarker for the severity of SCI patients at the National Rehabilitation Center, gaining an interest in spinal cord research. In my postdoctoral fellow in US, my current research focuses on the cellular mechanisms of neuronal plasticity and functional recovery following traumatic central nervous system injury at UCSF Brain and Spinal Injury Center. I hope that our fruitful projects might serve as patients for allowing to acquire essential functions again leading to improved quality of life.


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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pedoia V, Haefeli J, Morioka K, Teng HL, Nardo L, Souza RB, Ferguson AR, Majumdar S. MRI and biomechanics multidimensional data analysis reveals R2 -R1ρ as an early predictor of cartilage lesion progression in knee osteoarthritis. J Magn Reson Imaging. 2017 May 04. PMID: 28471543.
      View in: PubMed
    2. Ryu Y, Ogata T, Nagao M, Kitamura T, Morioka K, Ichihara Y, Doi T, Sawada Y, Akai M, Nishimura R, Fujita N. The swimming test is effective for evaluating spasticity after contusive spinal cord injury. PLoS One. 2017; 12(2):e0171937. PMID: 28182676.
      View in: PubMed
    3. Haefeli J, Huie JR, Morioka K, Ferguson AR. Assessments of Sensory Plasticity after Spinal Cord Injury across Species. Neurosci Lett. 2016 Dec 19. PMID: 28007646.
      View in: PubMed
    4. Huie JR, Morioka K, Haefeli J, Ferguson AR. What is Being Trained? How Divergent Forms of Plasticity Compete to Shape Locomotor Recovery after Spinal Cord Injury. J Neurotrauma. 2016 Nov 22. PMID: 27875927.
      View in: PubMed
    5. Ishii K, Morioka K . Complication, rehabilitation, and pharmacological therapy in the patient with acute spinal cord injury. Orthopedic Surgery. 2016; 35(70):220-5.
    6. Okazaki R, Doi T, Hayakawa K, Morioka K, Imamura O, Takishima K, Hamanoue M, Sawada Y, Nagao M, Tanaka S, Ogata T. The crucial role of Erk2 in demyelinating inflammation in the central nervous system. J Neuroinflammation. 2016; 13(1):235. PMID: 27596241; PMCID: PMC5011945.
    7. Ishii K, Morioka K . Changes in treatment strategies for cervical spinal cord injury. Journal of Joint Surgery. 2016; 35(6):580-7.
    8. Hamanoue M, Morioka K, Ohsawa I, Ohsawa K, Kobayashi M, Tsuburaya K, Akasaka Y, Mikami T, Ogata T, Takamatsu K. Cell-permeable p38?MAP kinase promotes migration of adult neural stem/progenitor cells. Sci Rep. 2016; 6:24279. PMID: 27067799.
      View in: PubMed
    9. Ota H, Emaminejad S, Gao Y, Zhao A, Wu E, Challa S, Chen K, Fahad HM, Jha AK, Kiriya D, Gao W, Shiraki H, Morioka K, Ferguson AR, Healy KE, Davis RW, Javey A. Application of 3D printing for smart objects with embedded electronic sensors and systems. Adv. Mater. Technol. 2016; 1(1):1600013.
    10. Hayakawa K, Okazaki R, Morioka K, Nakamura K, Tanaka S, Ogata T. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. J Neurosci Res. 2014 Dec; 92(12):1647-58. PMID: 25044014.
      View in: PubMed
    11. Hayakawa K, Okazaki R, Ishii K, Ueno T, Izawa N, Tanaka Y, Toyooka S, Matsuoka N, Morioka K, Ohori Y, Nakamura K, Akai M, Tobimatsu Y, Hamabe Y, Ogata T. Phosphorylated neurofilament subunit NF-H as a biomarker for evaluating the severity of spinal cord injury patients, a pilot study. Spinal Cord. 2012 Jul; 50(7):493-6. PMID: 22270191.
      View in: PubMed
    12. Ogata T, Morioka K . Current Status of Central Nervous System Regeneration. Journal of therapy. 2011; 93(2):314-8.
    13. Ogata T, Ueno T, Hoshikawa S, Ito J, Okazaki R, Hayakawa K, Morioka K, Yamamoto S, Nakamura K, Tanaka S, Akai M. Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage. Neuroscience. 2011 Mar 10; 176:132-41. PMID: 21167918.
      View in: PubMed
    14. Morioka K, Tanikawa C, Ochi K, Daigo Y, Katagiri T, Kawano H, Kawaguchi H, Myoui A, Yoshikawa H, Naka N, Araki N, Kudawara I, Ieguchi M, Nakamura K, Nakamura Y, Matsuda K. Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Sci. 2009 Jul; 100(7):1227-33. PMID: 19486338.
      View in: PubMed
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