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    Keith Mostov, MD, PhD

    SchoolUCSF School of Medicine
    Address600 16th Street
    San Francisco CA 94158
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      Collapse Overview 
      Collapse Overview
      Epithelial polarity, morphogenesis and regeneration.

      The most fundamental type of organization of cells in metazoa is that of epithelia. Epithelial cells form sheets of cells that line surfaces and internal cavities. The simplest metazoa, such as hydra, consist largely of two concentric cylinders of epithelial cell sheets. Most internal organs in higher animals, such as the respiratory, digestive, genito-urinary and vascular systems are lined by a single layer of epithelial cells. We are studying the structure and polarity of individual epithelial cells, how they are organized into multicellular tissues and organs, and how these are repaired and regenerate in response to injury. We use cell and organotypic culture, mice and in silico modeling, combining live imaging, biochemistry and genetics.

      Collapse Interests
      Host-pathogen interaction, Pseudomonas aeruginosa

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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Peng J, Awad A, Sar S, Hamze Komaiha O, Moyano R, Rayal A, Samuel D, Shewan A, Vanhaesebroeck B, Mostov K, Gassama-Diagne A. Phosphoinositide 3-kinase p110d promotes lumen formation through the enhancement of apico-basal polarity and basal membrane organization. Nat Commun. 2015; 6:5937.
        View in: PubMed
      2. Bryant DM, Roignot J, Datta A, Overeem AW, Kim M, Yu W, Peng X, Eastburn DJ, Ewald AJ, Werb Z, Mostov KE. A molecular switch for the orientation of epithelial cell polarization. Dev Cell. 2014 Oct 27; 31(2):171-87.
        View in: PubMed PMC4248238
      3. Nedvetsky PI, Emmerson E, Finley JK, Ettinger A, Cruz-Pacheco N, Prochazka J, Haddox CL, Northrup E, Hodges C, Mostov KE, Hoffman MP, Knox SM. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland. Dev Cell. 2014 Aug 25; 30(4):449-62.
        View in: PubMed PMC4155578
      4. Tran CS, Eran Y, Ruch TR, Bryant DM, Datta A, Brakeman P, Kierbel A, Wittmann T, Metzger RJ, Mostov KE, Engel JN. Host cell polarity proteins participate in innate immunity to Pseudomonas aeruginosa infection. Cell Host Microbe. 2014 May 14; 15(5):636-43.
        View in: PubMed PMC4062193
      5. Kwon SH, Liu KD, Mostov KE. Intercellular transfer of GPRC5B via exosomes drives HGF-mediated outward growth. Curr Biol. 2014 Jan 20; 24(2):199-204.
        View in: PubMed PMC3938203
      6. Cerruti B, Puliafito A, Shewan AM, Yu W, Combes AN, Little MH, Chianale F, Primo L, Serini G, Mostov KE, Celani A, Gamba A. Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures. J Cell Biol. 2013 Oct 28; 203(2):359-72.
        View in: PubMed PMC3812962
      7. Rousso T, Shewan AM, Mostov KE, Schejter ED, Shilo BZ. Apical targeting of the formin Diaphanous in Drosophila tubular epithelia. Elife. 2013; 2:e00666.
        View in: PubMed PMC3707080
      8. Roignot J, Peng X, Mostov K. Polarity in mammalian epithelial morphogenesis. Cold Spring Harb Perspect Biol. 2013 Feb; 5(2).
        View in: PubMed
      9. Cai L, Mostov KE. Cell height: Tao rising. J Cell Biol. 2012 Dec 24; 199(7):1023-4.
        View in: PubMed PMC3529524
      10. Gálvez-Santisteban M, Rodriguez-Fraticelli AE, Bryant DM, Vergarajauregui S, Yasuda T, Bañón-Rodríguez I, Bernascone I, Datta A, Spivak N, Young K, Slim CL, Brakeman PR, Fukuda M, Mostov KE, Martín-Belmonte F. Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol. 2012 Aug; 14(8):838-49.
        View in: PubMed PMC3433678
      11. Senga K, Mostov KE, Mitaka T, Miyajima A, Tanimizu N. Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Mol Biol Cell. 2012 Aug; 23(15):2845-55.
        View in: PubMed PMC3408412
      12. Nedvetsky PI, Kwon SH, Debnath J, Mostov KE. Cyclic AMP regulates formation of mammary epithelial acini in vitro. Mol Biol Cell. 2012 Aug; 23(15):2973-81.
        View in: PubMed PMC3408423
      13. Eastburn DJ, Zegers MM, Mostov KE. Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1-HSP90. J Cell Sci. 2012 Sep 1; 125(Pt 17):4147-57.
        View in: PubMed PMC3482320
      14. Su T, Chapin SJ, Bryant DM, Shewan AM, Young K, Mostov KE. Reduced immunoglobulin A transcytosis associated with immunoglobulin A nephropathy and nasopharyngeal carcinoma. J Biol Chem. 2011 Dec 30; 286(52):44921-5.
        View in: PubMed PMC3247984
      15. Cheung ID, Bagnat M, Ma TP, Datta A, Evason K, Moore JC, Lawson ND, Mostov KE, Moens CB, Stainier DY. Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Dev Biol. 2012 Jan 1; 361(1):68-78.
        View in: PubMed PMC3235368
      16. Shewan A, Eastburn DJ, Mostov K. Phosphoinositides in cell architecture. Cold Spring Harb Perspect Biol. 2011 Aug; 3(8):a004796.
        View in: PubMed PMC3140688
      17. Lepanto P, Bryant DM, Rossello J, Datta A, Mostov KE, Kierbel A. Pseudomonas aeruginosa interacts with epithelial cells rapidly forming aggregates that are internalized by a Lyn-dependent mechanism. Cell Microbiol. 2011 Aug; 13(8):1212-22.
        View in: PubMed PMC3813436
      18. Marciano DK, Brakeman PR, Lee CZ, Spivak N, Eastburn DJ, Bryant DM, Beaudoin GM, Hofmann I, Mostov KE, Reichardt LF. p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development. 2011 May; 138(10):2099-109.
        View in: PubMed PMC3082309
      19. Engelberg JA, Datta A, Mostov KE, Hunt CA. MDCK cystogenesis driven by cell stabilization within computational analogues. PLoS Comput Biol. 2011 Apr; 7(4):e1002030.
        View in: PubMed PMC3072361
      20. Datta A, Bryant DM, Mostov KE. Molecular regulation of lumen morphogenesis. Curr Biol. 2011 Feb 8; 21(3):R126-36.
        View in: PubMed PMC3771703
      21. Roland JT, Bryant DM, Datta A, Itzen A, Mostov KE, Goldenring JR. Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2789-94.
        View in: PubMed PMC3041130
      22. Kwon SH, Nedvetsky PI, Mostov KE. Transcriptional profiling identifies TNS4 function in epithelial tubulogenesis. Curr Biol. 2011 Jan 25; 21(2):161-6.
        View in: PubMed PMC3031161
      23. Su T, Bryant DM, Luton F, Vergés M, Ulrich SM, Hansen KC, Datta A, Eastburn DJ, Burlingame AL, Shokat KM, Mostov KE. A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol. 2010 Dec; 12(12):1143-53.
        View in: PubMed PMC3072784
      24. Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, Mostov K, Huisken J, Stainier DY. Cse1l is a negative regulator of CFTR-dependent fluid secretion. Curr Biol. 2010 Oct 26; 20(20):1840-5.
        View in: PubMed PMC2963654
      25. Bryant DM, Datta A, Rodríguez-Fraticelli AE, Peränen J, Martín-Belmonte F, Mostov KE. A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol. 2010 Nov; 12(11):1035-45.
        View in: PubMed PMC2975675
      26. Kim M, O'Brien LE, Kwon SH, Mostov KE. STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis. Mol Biol Cell. 2010 Nov 15; 21(22):3926-33.
        View in: PubMed PMC2982126
      27. Rodriguez-Fraticelli AE, Vergarajauregui S, Eastburn DJ, Datta A, Alonso MA, Mostov K, Martín-Belmonte F. The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis. J Cell Biol. 2010 May 17; 189(4):725-38.
        View in: PubMed PMC2872911
      28. Eastburn DJ, Mostov KE. Laying the foundation for epithelia: insights into polarized basement membrane deposition. EMBO Rep. 2010 May; 11(5):329-30.
        View in: PubMed PMC2868545
      29. Kim SH, Matthay MA, Mostov K, Hunt CA. Simulation of lung alveolar epithelial wound healing in vitro. J R Soc Interface. 2010 Aug 6; 7(49):1157-70.
        View in: PubMed PMC2894878
      30. Mostov K, Liptsen E, Boutchko R. Medical applications of shortwave FM radar: remote monitoring of cardiac and respiratory motion. Med Phys. 2010 Mar; 37(3):1332-8.
        View in: PubMed PMC2847938
      31. Kim SH, Debnath J, Mostov K, Park S, Hunt CA. A computational approach to resolve cell level contributions to early glandular epithelial cancer progression. BMC Syst Biol. 2009; 3:122.
        View in: PubMed PMC2814811
      32. Bucior I, Mostov K, Engel JN. Pseudomonas aeruginosa-mediated damage requires distinct receptors at the apical and basolateral surfaces of the polarized epithelium. Infect Immun. 2010 Mar; 78(3):939-53.
        View in: PubMed PMC2825949
      33. Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13; 139(4):660-2.
        View in: PubMed PMC2900917
      34. Kim SH, Park S, Mostov K, Debnath J, Hunt CA. Computational investigation of epithelial cell dynamic phenotype in vitro. Theor Biol Med Model. 2009; 6:8.
        View in: PubMed PMC2696420
      35. Luton F, Hexham MJ, Zhang M, Mostov KE. Identification of a cytoplasmic signal for apical transcytosis. Traffic. 2009 Aug; 10(8):1128-42.
        View in: PubMed PMC2920487
      36. Tanimizu N, Miyajima A, Mostov KE. Liver progenitor cells fold up a cell monolayer into a double-layered structure during tubular morphogenesis. Mol Biol Cell. 2009 May; 20(9):2486-94.
        View in: PubMed PMC2675627
      37. Kim SH, Yu W, Mostov K, Matthay MA, Hunt CA. A computational approach to understand in vitro alveolar morphogenesis. PLoS One. 2009; 4(3):e4819.
        View in: PubMed PMC2653231
      38. Brakeman PR, Liu KD, Shimizu K, Takai Y, Mostov KE. Nectin proteins are expressed at early stages of nephrogenesis and play a role in renal epithelial cell morphogenesis. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F564-74.
        View in: PubMed PMC2660185
      39. Bryant DM, Mostov KE. From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol. 2008 Nov; 9(11):887-901.
        View in: PubMed PMC2921794
      40. Shafikhani SH, Mostov K, Engel J. Focal adhesion components are essential for mammalian cell cytokinesis. Cell Cycle. 2008 Sep 15; 7(18):2868-76.
        View in: PubMed PMC2745397
      41. Yu W, Shewan AM, Brakeman P, Eastburn DJ, Datta A, Bryant DM, Fan QW, Weiss WA, Zegers MM, Mostov KE. Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Rep. 2008 Sep; 9(9):923-9.
        View in: PubMed PMC2529350
      42. Martín-Belmonte F, Yu W, Rodríguez-Fraticelli AE, Ewald AJ, Ewald A, Werb Z, Alonso MA, Mostov K. Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr Biol. 2008 Apr 8; 18(7):507-13.
        View in: PubMed PMC2405957
      43. Martin-Belmonte F, Mostov K. Regulation of cell polarity during epithelial morphogenesis. Curr Opin Cell Biol. 2008 Apr; 20(2):227-34.
        View in: PubMed
      44. Engelberg JA, Kim M, Mostov KE, Hunt CA. In silico simulation of epithelial cell tubulogenesis. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1036-9.
        View in: PubMed
      45. Bryant D, Mostov K. Development: inflationary pressures. Nature. 2007 Oct 4; 449(7162):549-50.
        View in: PubMed
      46. Jacobson C, Mostov K. Catch the KIF5B train to the apical surface. Dev Cell. 2007 Oct; 13(4):457-8.
        View in: PubMed
      47. Liu KD, Datta A, Yu W, Brakeman PR, Jou TS, Matthay MA, Mostov KE. Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1633-40.
        View in: PubMed
      48. Bagnat M, Cheung ID, Mostov KE, Stainier DY. Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol. 2007 Aug; 9(8):954-60.
        View in: PubMed
      49. Kim M, Datta A, Brakeman P, Yu W, Mostov KE. Polarity proteins PAR6 and aPKC regulate cell death through GSK-3beta in 3D epithelial morphogenesis. J Cell Sci. 2007 Jul 15; 120(Pt 14):2309-17.
        View in: PubMed
      50. Krtolica A, Genbacev O, Escobedo C, Zdravkovic T, Nordstrom A, Vabuena D, Nath A, Simon C, Mostov K, Fisher SJ. Disruption of apical-basal polarity of human embryonic stem cells enhances hematoendothelial differentiation. Stem Cells. 2007 Sep; 25(9):2215-23.
        View in: PubMed
      51. Martin-Belmonte F, Mostov K. Phosphoinositides control epithelial development. Cell Cycle. 2007 Aug 15; 6(16):1957-61.
        View in: PubMed
      52. Bryant DM, Kerr MC, Hammond LA, Joseph SR, Mostov KE, Teasdale RD, Stow JL. EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. J Cell Sci. 2007 May 15; 120(Pt 10):1818-28.
        View in: PubMed
      53. Kierbel A, Gassama-Diagne A, Rocha C, Radoshevich L, Olson J, Mostov K, Engel J. Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane. J Cell Biol. 2007 Apr 9; 177(1):21-7.
        View in: PubMed PMC2064102
      54. Leroy P, Mostov KE. Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis. Mol Biol Cell. 2007 May; 18(5):1943-52.
        View in: PubMed PMC1855025
      55. Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol Biol Cell. 2007 May; 18(5):1693-700.
        View in: PubMed PMC1855040
      56. Tanimizu N, Miyajima A, Mostov KE. Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture. Mol Biol Cell. 2007 Apr; 18(4):1472-9.
        View in: PubMed PMC1838984
      57. Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, Gerke V, Mostov K. PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell. 2007 Jan 26; 128(2):383-97.
        View in: PubMed PMC1865103
      58. Levin M, Ewald AJ, McMahon M, Werb Z, Mostov K. A model of intussusceptive angiogenesis. Novartis Found Symp. 2007; 283:37-42; discussion 42-5, 238-41.
        View in: PubMed
      59. Reiter JF, Mostov K. Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle. Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49):18383-4.
        View in: PubMed PMC1693671
      60. Vergés M, Sebastián I, Mostov KE. Phosphoinositide 3-kinase regulates the role of retromer in transcytosis of the polymeric immunoglobulin receptor. Exp Cell Res. 2007 Feb 15; 313(4):707-18.
        View in: PubMed PMC1810347
      61. Gassama-Diagne A, Yu W, ter Beest M, Martin-Belmonte F, Kierbel A, Engel J, Mostov K. Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nat Cell Biol. 2006 Sep; 8(9):963-70.
        View in: PubMed
      62. Grant MR, Mostov KE, Tlsty TD, Hunt CA. Simulating properties of in vitro epithelial cell morphogenesis. PLoS Comput Biol. 2006 Oct 6; 2(10):e129.
        View in: PubMed PMC1592363
      63. Mostov K, Martin-Belmonte F. Developmental biology: the hole picture. Nature. 2006 Jul 27; 442(7101):363-4.
        View in: PubMed
      64. Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell. 2006 May; 9(5):341-9.
        View in: PubMed PMC2925230
      65. Mostov KE. mTOR is out of control in polycystic kidney disease. Proc Natl Acad Sci U S A. 2006 Apr 4; 103(14):5247-8.
        View in: PubMed PMC1459339
      66. O'Brien LE, Yu W, Tang K, Jou TS, Zegers MM, Mostov KE. Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures. Methods Enzymol. 2006; 406:676-91.
        View in: PubMed
      67. ter Beest MB, Chapin SJ, Avrahami D, Mostov KE. The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells. Mol Biol Cell. 2005 Dec; 16(12):5784-92.
        View in: PubMed PMC1289421
      68. Kierbel A, Gassama-Diagne A, Mostov K, Engel JN. The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization. Mol Biol Cell. 2005 May; 16(5):2577-85.
        View in: PubMed PMC1087259
      69. Mostov K, Brakeman P, Datta A, Gassama A, Katz L, Kim M, Leroy P, Levin M, Liu K, Martin F, O'Brien LE, Verges M, Su T, Tang K, Tanimizu N, Yamaji T, Yu W. Formation of multicellular epithelial structures. Novartis Found Symp. 2005; 269:193-200; discussion 200-5, 223-30.
        View in: PubMed
      70. Yu W, Datta A, Leroy P, O'Brien LE, Mak G, Jou TS, Matlin KS, Mostov KE, Zegers MM. Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol Biol Cell. 2005 Feb; 16(2):433-45.
        View in: PubMed PMC545874
      71. Tanimizu N, Saito H, Mostov K, Miyajima A. Long-term culture of hepatic progenitors derived from mouse Dlk+ hepatoblasts. J Cell Sci. 2004 Dec 15; 117(Pt 26):6425-34.
        View in: PubMed
      72. Vergés M, Luton F, Gruber C, Tiemann F, Reinders LG, Huang L, Burlingame AL, Haft CR, Mostov KE. The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol. 2004 Aug; 6(8):763-9.
        View in: PubMed
      73. O'Brien LE, Tang K, Kats ES, Schutz-Geschwender A, Lipschutz JH, Mostov KE. ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Dev Cell. 2004 Jul; 7(1):21-32.
        View in: PubMed
      74. Matsumura S, Van De Water J, Leung P, Odin JA, Yamamoto K, Gores GJ, Mostov K, Ansari AA, Coppel RL, Shiratori Y, Gershwin ME. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. Hepatology. 2004 May; 39(5):1415-22.
        View in: PubMed
      75. Kazmierczak BI, Mostov K, Engel JN. Epithelial cell polarity alters Rho-GTPase responses to Pseudomonas aeruginosa. Mol Biol Cell. 2004 Feb; 15(2):411-9.
        View in: PubMed PMC329196
      76. Pollack AL, Apodaca G, Mostov KE. Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C482-94.
        View in: PubMed
      77. Zegers MM, Forget MA, Chernoff J, Mostov KE, ter Beest MB, Hansen SH. Pak1 and PIX regulate contact inhibition during epithelial wound healing. EMBO J. 2003 Aug 15; 22(16):4155-65.
        View in: PubMed PMC175788
      78. Mostov KE. Epithelial polarity and morphogenesis. Methods. 2003 Jul; 30(3):189-90.
        View in: PubMed
      79. Lai JF, Juang SH, Hung YM, Cheng HY, Cheng TL, Mostov KE, Jou TS. An ecdysone and tetracycline dual regulatory expression system for studies on Rac1 small GTPase-mediated signaling. Am J Physiol Cell Physiol. 2003 Sep; 285(3):C711-9.
        View in: PubMed
      80. Mostov K, Su T, ter Beest M. Polarized epithelial membrane traffic: conservation and plasticity. Nat Cell Biol. 2003 Apr; 5(4):287-93.
        View in: PubMed
      81. Zegers MM, O'Brien LE, Yu W, Datta A, Mostov KE. Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol. 2003 Apr; 13(4):169-76.
        View in: PubMed
      82. Lipschutz JH, Lingappa VR, Mostov KE. The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. J Biol Chem. 2003 Jun 6; 278(23):20954-60.
        View in: PubMed
      83. Mostov K, Zegers M. Cell biology: Just mix and patch. Nature. 2003 Mar 20; 422(6929):267-8.
        View in: PubMed
      84. Yu W, O'Brien LE, Wang F, Bourne H, Mostov KE, Zegers MM. Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol Biol Cell. 2003 Feb; 14(2):748-63.
        View in: PubMed PMC150005
      85. van Ijzendoorn SC, Mostov KE, Hoekstra D. Role of rab proteins in epithelial membrane traffic. Int Rev Cytol. 2003; 232:59-88.
        View in: PubMed
      86. O'Brien LE, Zegers MM, Mostov KE. Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol. 2002 Jul; 3(7):531-7.
        View in: PubMed
      87. Lipschutz JH, Mostov KE. Exocytosis: the many masters of the exocyst. Curr Biol. 2002 Mar 19; 12(6):R212-4.
        View in: PubMed
      88. van IJzendoorn SC, Tuvim MJ, Weimbs T, Dickey BF, Mostov KE. Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Dev Cell. 2002 Feb; 2(2):219-28.
        View in: PubMed
      89. von Zastrow M, Mostov K. Signal transduction. A new thread in an intricate web. Science. 2001 Nov 30; 294(5548):1845-7.
        View in: PubMed
      90. Lipschutz JH, O'Brien LE, Altschuler Y, Avrahami D, Nguyen Y, Tang K, Mostov KE. Analysis of membrane traffic in polarized epithelial cells. Curr Protoc Cell Biol. 2001 Nov; Chapter 15:Unit 15.5.
        View in: PubMed
      91. O'Brien LE, Jou TS, Pollack AL, Zhang Q, Hansen SH, Yurchenco P, Mostov KE. Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nat Cell Biol. 2001 Sep; 3(9):831-8.
        View in: PubMed
      92. Mangravite LM, Lipschutz JH, Mostov KE, Giacomini KM. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line. Am J Physiol Renal Physiol. 2001 May; 280(5):F879-85.
        View in: PubMed
      93. Kazmierczak BI, Jou TS, Mostov K, Engel JN. Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells. Cell Microbiol. 2001 Feb; 3(2):85-98.
        View in: PubMed
      94. Kazmierczak BI, Mostov K, Engel JN. Interaction of bacterial pathogens with polarized epithelium. Annu Rev Microbiol. 2001; 55:407-35.
        View in: PubMed
      95. Lipschutz JH, Guo W, O'Brien LE, Nguyen YH, Novick P, Mostov KE. Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. Mol Biol Cell. 2000 Dec; 11(12):4259-75.
        View in: PubMed PMC15071
      96. Hansen SH, Zegers MM, Woodrow M, Rodriguez-Viciana P, Chardin P, Mostov KE, McMahon M. Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway. Mol Cell Biol. 2000 Dec; 20(24):9364-75.
        View in: PubMed PMC102193
      97. van Ooij C, Kalman L. Host cell-derived sphingolipids are required for the intracellular growth of Chlamydia trachomatis. Cell Microbiol. 2000 Dec; 2(6):627-37.
        View in: PubMed
      98. van Ijzendoorn SC, Mostov KE. Connecting apical endocytosis to the intracellular traffic infrastructure in polarized hepatocytes. Gastroenterology. 2000 Dec; 119(6):1791-4.
        View in: PubMed
      99. Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation. Biochemistry. 2000 Nov 14; 39(45):13916-24.
        View in: PubMed
      100. Trejo J, Altschuler Y, Fu HW, Mostov KE, Coughlin SR. Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits. J Biol Chem. 2000 Oct 6; 275(40):31255-65.
        View in: PubMed
      101. Zhang JR, Mostov KE, Lamm ME, Nanno M, Shimida S, Ohwaki M, Tuomanen E. The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell. 2000 Sep 15; 102(6):827-37.
        View in: PubMed
      102. Low SH, Miura M, Roche PA, Valdez AC, Mostov KE, Weimbs T. Intracellular redirection of plasma membrane trafficking after loss of epithelial cell polarity. Mol Biol Cell. 2000 Sep; 11(9):3045-60.
        View in: PubMed PMC14974
      103. Mostov KE, Verges M, Altschuler Y. Membrane traffic in polarized epithelial cells. Curr Opin Cell Biol. 2000 Aug; 12(4):483-90.
        View in: PubMed
      104. Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. J Biol Chem. 2000 Jul 7; 275(27):20717-25.
        View in: PubMed
      105. Wang E, Brown PS, Aroeti B, Chapin SJ, Mostov KE, Dunn KW. Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome. Traffic. 2000 Jun; 1(6):480-93.
        View in: PubMed
      106. Brown PS, Wang E, Aroeti B, Chapin SJ, Mostov KE, Dunn KW. Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling. Traffic. 2000 Feb; 1(2):124-40.
        View in: PubMed
      107. Mostov K, ter Beest MB, Chapin SJ. Catch the mu1B train to the basolateral surface. Cell. 1999 Oct 15; 99(2):121-2.
        View in: PubMed
      108. Altschuler Y, Liu S, Katz L, Tang K, Hardy S, Brodsky F, Apodaca G, Mostov K. ADP-ribosylation factor 6 and endocytosis at the apical surface of Madin-Darby canine kidney cells. J Cell Biol. 1999 Oct 4; 147(1):7-12.
        View in: PubMed PMC2164974
      109. Luton F, Vergés M, Vaerman JP, Sudol M, Mostov KE. The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo. Mol Cell. 1999 Oct; 4(4):627-32.
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      110. Vergés M, Havel RJ, Mostov KE. A tubular endosomal fraction from rat liver: biochemical evidence of receptor sorting by default. Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10146-51.
        View in: PubMed PMC17857
      111. Comolli JC, Waite LL, Mostov KE, Engel JN. Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa. Infect Immun. 1999 Jul; 67(7):3207-14.
        View in: PubMed PMC116497
      112. Luton F, Mostov KE. Transduction of basolateral-to-apical signals across epithelial cells: ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals. Mol Biol Cell. 1999 May; 10(5):1409-27.
        View in: PubMed PMC25293
      113. Altschuler Y, Barbas SM, Terlecky LJ, Tang K, Hardy S, Mostov KE, Schmid SL. Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms. J Cell Biol. 1998 Dec 28; 143(7):1871-81.
        View in: PubMed PMC2175237
      114. Pollack AL, Runyan RB, Mostov KE. Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis. Dev Biol. 1998 Dec 1; 204(1):64-79.
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      115. Malmborg AC, Shultz DB, Luton F, Mostov KE, Richly E, Leung PS, Benson GD, Ansari AA, Coppel RL, Gershwin ME, Van de Water J. Penetration and co-localization in MDCK cell mitochondria of IgA derived from patients with primary biliary cirrhosis. J Autoimmun. 1998 Oct; 11(5):573-80.
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      116. Fleiszig SM, Vallas V, Jun CH, Mok L, Balkovetz DF, Roth MG, Mostov KE. Susceptibility of epithelial cells to Pseudomonas aeruginosa invasion and cytotoxicity is upregulated by hepatocyte growth factor. Infect Immun. 1998 Jul; 66(7):3443-6.
        View in: PubMed PMC108367
      117. Weimbs T, Mostov K, Low SH, Hofmann K. A model for structural similarity between different SNARE complexes based on sequence relationships. Trends Cell Biol. 1998 Jul; 8(7):260-2.
        View in: PubMed
      118. Luton F, Cardone MH, Zhang M, Mostov KE. Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor. Mol Biol Cell. 1998 Jul; 9(7):1787-802.
        View in: PubMed PMC25419
      119. Low SH, Chapin SJ, Wimmer C, Whiteheart SW, Kömüves LG, Mostov KE, Weimbs T. The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells. J Cell Biol. 1998 Jun 29; 141(7):1503-13.
        View in: PubMed PMC2133007
      120. Bose S, Chapin SJ, Seetharam S, Feix J, Mostov KE, Seetharam B. Brefeldin A (BFA) inhibits basolateral membrane (BLM) delivery and dimerization of transcobalamin II receptor in human intestinal epithelial Caco-2 cells. BFA effects on BLM cholesterol content. J Biol Chem. 1998 Jun 26; 273(26):16163-9.
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      121. Singer KL, Mostov KE. Dimerization of the polymeric immunoglobulin receptor controls its transcytotic trafficking. Mol Biol Cell. 1998 Apr; 9(4):901-15.
        View in: PubMed PMC25316
      122. Hauser AR, Fleiszig S, Kang PJ, Mostov K, Engel JN. Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells. Infect Immun. 1998 Apr; 66(4):1413-20.
        View in: PubMed PMC108068
      123. Low SH, Roche PA, Anderson HA, van Ijzendoorn SC, Zhang M, Mostov KE, Weimbs T. Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells. J Biol Chem. 1998 Feb 6; 273(6):3422-30.
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      124. Weimbs T, Low SH, Chapin SJ, Mostov KE. Apical targeting in polarized epithelial cells: There's more afloat than rafts. Trends Cell Biol. 1997 Oct; 7(10):393-9.
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      125. Fleiszig SM, Evans DJ, Do N, Vallas V, Shin S, Mostov KE. Epithelial cell polarity affects susceptibility to Pseudomonas aeruginosa invasion and cytotoxicity. Infect Immun. 1997 Jul; 65(7):2861-7.
        View in: PubMed PMC175402
      126. Pollack AL, Barth AI, Altschuler Y, Nelson WJ, Mostov KE. Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis. J Cell Biol. 1997 Jun 30; 137(7):1651-62.
        View in: PubMed PMC2137813
      127. Kang PJ, Hauser AR, Apodaca G, Fleiszig SM, Wiener-Kronish J, Mostov K, Engel JN. Identification of Pseudomonas aeruginosa genes required for epithelial cell injury. Mol Microbiol. 1997 Jun; 24(6):1249-62.
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      128. Mostov K, Werb Z. Journey across the osteoclast. Science. 1997 Apr 11; 276(5310):219-20.
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      129. Weimbs T, Low SH, Chapin SJ, Mostov KE, Bucher P, Hofmann K. A conserved domain is present in different families of vesicular fusion proteins: a new superfamily. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):3046-51.
        View in: PubMed PMC20319
      130. Barth AI, Pollack AL, Altschuler Y, Mostov KE, Nelson WJ. NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J Cell Biol. 1997 Feb 10; 136(3):693-706.
        View in: PubMed PMC2134296
      131. Balkovetz DF, Pollack AL, Mostov KE. Hepatocyte growth factor alters the polarity of Madin-Darby canine kidney cell monolayers. J Biol Chem. 1997 Feb 7; 272(6):3471-7.
        View in: PubMed
      132. Fleiszig SM, Wiener-Kronish JP, Miyazaki H, Vallas V, Mostov KE, Kanada D, Sawa T, Yen TS, Frank DW. Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S. Infect Immun. 1997 Feb; 65(2):579-86.
        View in: PubMed PMC176099
      133. Low SH, Chapin SJ, Weimbs T, Kömüves LG, Bennett MK, Mostov KE. Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 1996 Dec; 7(12):2007-18.
        View in: PubMed PMC276046
      134. Reich V, Mostov K, Aroeti B. The basolateral sorting signal of the polymeric immunoglobulin receptor contains two functional domains. J Cell Sci. 1996 Aug; 109 ( Pt 8):2133-9.
        View in: PubMed
      135. Enrich C, Apodaca G, Mostov KE. Calmodulin regulates the intracellular trafficking in epithelial cells. Z Gastroenterol. 1996 Jun; 34 Suppl 3:83-5.
        View in: PubMed
      136. Cardone MH, Smith BL, Mennitt PA, Mochly-Rosen D, Silver RB, Mostov KE. Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis. J Cell Biol. 1996 Jun; 133(5):997-1005.
        View in: PubMed PMC2120848
      137. Apodaca G, Cardone MH, Whiteheart SW, DasGupta BR, Mostov KE. Reconstitution of transcytosis in SLO-permeabilized MDCK cells: existence of an NSF-dependent fusion mechanism with the apical surface of MDCK cells. EMBO J. 1996 Apr 1; 15(7):1471-81.
        View in: PubMed PMC450054
      138. Chapin SJ, Enrich C, Aroeti B, Havel RJ, Mostov KE. Calmodulin binds to the basolateral targeting signal of the polymeric immunoglobulin receptor. J Biol Chem. 1996 Jan 19; 271(3):1336-42.
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      139. Cardone M, Mostov K. Wortmannin inhibits transcytosis of dimeric IgA by the polymeric immunoglobulin receptor. FEBS Lett. 1995 Nov 27; 376(1-2):74-6.
        View in: PubMed
      140. Song W, Vaerman JP, Mostov KE. Dimeric and tetrameric IgA are transcytosed equally by the polymeric Ig receptor. J Immunol. 1995 Jul 15; 155(2):715-21.
        View in: PubMed
      141. Ma JK, Hiatt A, Hein M, Vine ND, Wang F, Stabila P, van Dolleweerd C, Mostov K, Lehner T. Generation and assembly of secretory antibodies in plants. Science. 1995 May 5; 268(5211):716-9.
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      142. Apodaca G, Bomsel M, Lindstedt R, Engel J, Frank D, Mostov KE, Wiener-Kronish J. Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing. Infect Immun. 1995 Apr; 63(4):1541-51.
        View in: PubMed PMC173187
      143. Mostov KE. Regulation of protein traffic in polarized epithelial cells. Histol Histopathol. 1995 Apr; 10(2):423-31.
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      144. Mostov KE, Cardone MH. Regulation of protein traffic in polarized epithelial cells. Bioessays. 1995 Feb; 17(2):129-38.
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      145. Mostov KE, Altschuler Y, Chapin SJ, Enrich C, Low SH, Luton F, Richman-Eisenstat J, Singer KL, Tang K, Weimbs T. Regulation of protein traffic in polarized epithelial cells: the polymeric immunoglobulin receptor model. Cold Spring Harb Symp Quant Biol. 1995; 60:775-81.
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      146. Bonzelius F, Herman GA, Cardone MH, Mostov KE, Kelly RB. The polymeric immunoglobulin receptor accumulates in specialized endosomes but not synaptic vesicles within the neurites of transfected neuroendocrine PC12 cells. J Cell Biol. 1994 Dec; 127(6 Pt 1):1603-16.
        View in: PubMed PMC2120272
      147. Song W, Apodaca G, Mostov K. Transcytosis of the polymeric immunoglobulin receptor is regulated in multiple intracellular compartments. J Biol Chem. 1994 Nov 25; 269(47):29474-80.
        View in: PubMed
      148. Apodaca G, Enrich C, Mostov KE. The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in Madin-Darby canine kidney cells. J Biol Chem. 1994 Jul 22; 269(29):19005-13.
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      149. Okamoto CT, Song W, Bomsel M, Mostov KE. Rapid internalization of the polymeric immunoglobulin receptor requires phosphorylated serine 726. J Biol Chem. 1994 Jun 3; 269(22):15676-82.
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      150. Aroeti B, Mostov KE. Polarized sorting of the polymeric immunoglobulin receptor in the exocytotic and endocytotic pathways is controlled by the same amino acids. EMBO J. 1994 May 15; 13(10):2297-304.
        View in: PubMed PMC395093
      151. Bomsel M, Mostov KE. Both the Gs alpha and beta gamma subunits of the heterotrimeric G protein, Gs, control the sorting of the polymeric immunoglobulin receptor into transcytotic vesicles. Biochem Soc Trans. 1994 May; 22(2):463-8.
        View in: PubMed
      152. Apodaca G, Katz LA, Mostov KE. Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J Cell Biol. 1994 Apr; 125(1):67-86.
        View in: PubMed PMC2120019
      153. Crepaldi T, Pollack AL, Prat M, Zborek A, Mostov K, Comoglio PM. Targeting of the SF/HGF receptor to the basolateral domain of polarized epithelial cells. J Cell Biol. 1994 Apr; 125(2):313-20.
        View in: PubMed PMC2120024
      154. Cardone MH, Smith BL, Song W, Mochly-Rosen D, Mostov KE. Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells. J Cell Biol. 1994 Mar; 124(5):717-27.
        View in: PubMed PMC2119954
      155. Song W, Bomsel M, Casanova J, Vaerman JP, Mostov K. Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA. Proc Natl Acad Sci U S A. 1994 Jan 4; 91(1):163-6.
        View in: PubMed PMC42906
      156. Mostov KE. Transepithelial transport of immunoglobulins. Annu Rev Immunol. 1994; 12:63-84.
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      157. Bomsel M, Mostov KE. Possible role of both the alpha and beta gamma subunits of the heterotrimeric G protein, Gs, in transcytosis of the polymeric immunoglobulin receptor. J Biol Chem. 1993 Dec 5; 268(34):25824-35.
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      158. Aroeti B, Kosen PA, Kuntz ID, Cohen FE, Mostov KE. Mutational and secondary structural analysis of the basolateral sorting signal of the polymeric immunoglobulin receptor. J Cell Biol. 1993 Dec; 123(5):1149-60.
        View in: PubMed PMC2119873
      159. Apodaca G, Mostov KE. Transcytosis of placental alkaline phosphatase-polymeric immunoglobulin receptor fusion proteins is regulated by mutations of Ser664. J Biol Chem. 1993 Nov 5; 268(31):23712-9.
        View in: PubMed
      160. Apodaca G, Aroeti B, Tang K, Mostov KE. Brefeldin-A inhibits the delivery of the polymeric immunoglobulin receptor to the basolateral surface of MDCK cells. J Biol Chem. 1993 Sep 25; 268(27):20380-5.
        View in: PubMed
      161. Lindstedt R, Apodaca G, Barondes SH, Mostov KE, Leffler H. Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. J Biol Chem. 1993 Jun 5; 268(16):11750-7.
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      162. Chang MP, Mallet WG, Mostov KE, Brodsky FM. Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits. EMBO J. 1993 May; 12(5):2169-80.
        View in: PubMed PMC413438
      163. Mostov K. Protein traffic in polarized epithelial cells: the polymeric immunoglobulin receptor as a model system. J Cell Sci Suppl. 1993; 17:21-6.
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      164. Bomsel M, Mostov K. Role of heterotrimeric G proteins in membrane traffic. Mol Biol Cell. 1992 Dec; 3(12):1317-28.
        View in: PubMed PMC275702
      165. Okamoto CT, Shia SP, Bird C, Mostov KE, Roth MG. The cytoplasmic domain of the polymeric immunoglobulin receptor contains two internalization signals that are distinct from its basolateral sorting signal. J Biol Chem. 1992 May 15; 267(14):9925-32.
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      166. Mostov K, Apodaca G, Aroeti B, Okamoto C. Plasma membrane protein sorting in polarized epithelial cells. J Cell Biol. 1992 Feb; 116(3):577-83.
        View in: PubMed PMC2289323
      167. Aroeti B, Casanova J, Okamoto C, Cardone M, Pollack A, Tang K, Mostov K. Polymeric immunoglobulin receptor. Int Rev Cytol. 1992; 137B:157-68.
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      168. Casanova JE, Mishumi Y, Ikehara Y, Hubbard AL, Mostov KE. Direct apical sorting of rat liver dipeptidylpeptidase IV expressed in Madin-Darby canine kidney cells. J Biol Chem. 1991 Dec 25; 266(36):24428-32.
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      169. Mostov K. The polymeric immunoglobulin receptor. Semin Cell Biol. 1991 Dec; 2(6):411-8.
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      170. Bomsel M, Mostov K. Sorting of plasma membrane proteins in epithelial cells. Curr Opin Cell Biol. 1991 Aug; 3(4):647-53.
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      171. Casanova JE, Apodaca G, Mostov KE. An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor. Cell. 1991 Jul 12; 66(1):65-75.
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      172. Apodaca G, Bomsel M, Arden J, Breitfeld PP, Tang K, Mostov KE. The polymeric immunoglobulin receptor. A model protein to study transcytosis. J Clin Invest. 1991 Jun; 87(6):1877-82.
        View in: PubMed PMC296937
      173. Breitfeld PP, McKinnon WC, Mostov KE. Effect of nocodazole on vesicular traffic to the apical and basolateral surfaces of polarized MDCK cells. J Cell Biol. 1990 Dec; 111(6 Pt 1):2365-73.
        View in: PubMed PMC2116403
      174. Breitfeld PP, Casanova JE, McKinnon WC, Mostov KE. Deletions in the cytoplasmic domain of the polymeric immunoglobulin receptor differentially affect endocytotic rate and postendocytotic traffic. J Biol Chem. 1990 Aug 15; 265(23):13750-7.
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      175. Casanova JE, Breitfeld PP, Ross SA, Mostov KE. Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis. Science. 1990 May 11; 248(4956):742-5.
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      176. Le Bivic A, Sambuy Y, Mostov K, Rodriguez-Boulan E. Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. J Cell Biol. 1990 May; 110(5):1533-9.
        View in: PubMed PMC2200188
      177. Breitfeld PP, Casanova JE, Simister NE, Ross SA, McKinnon WC, Mostov KE. Transepithelial transport of immunoglobulins: a model of protein sorting and transcytosis. Am J Respir Cell Mol Biol. 1989 Oct; 1(4):257-62.
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      178. Breitfeld PP, Harris JM, Mostov KE. Postendocytotic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells. J Cell Biol. 1989 Aug; 109(2):475-86.
        View in: PubMed PMC2115734
      179. Breitfeld PP, Casanova JE, Simister NE, Ross SA, McKinnon WC, Mostov KE. Sorting signals. Curr Opin Cell Biol. 1989 Aug; 1(4):617-23.
        View in: PubMed
      180. Simister NE, Mostov KE. An Fc receptor structurally related to MHC class I antigens. Nature. 1989 Jan 12; 337(6203):184-7.
        View in: PubMed
      181. Simister NE, Mostov KE. Cloning and expression of the neonatal rat intestinal Fc receptor, a major histocompatibility complex class I antigen homolog. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:571-80.
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      182. Breitfeld PP, Casanova JE, Harris JM, Simister NE, Mostov KE. Expression and analysis of the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells using retroviral vectors. Methods Cell Biol. 1989; 32:329-37.
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      183. Breitfeld PP, Harris JM, Mostov KE. Cell biology of the IgA receptor in polarized epithelia. Monogr Allergy. 1988; 24:66-70.
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      184. Mostov KE, Breitfeld P, Harris JM. An anchor-minus form of the polymeric immunoglobulin receptor is secreted predominantly apically in Madin-Darby canine kidney cells. J Cell Biol. 1987 Nov; 105(5):2031-6.
        View in: PubMed PMC2114864
      185. Mostov KE, de Bruyn Kops A, Deitcher DL. Deletion of the cytoplasmic domain of the polymeric immunoglobulin receptor prevents basolateral localization and endocytosis. Cell. 1986 Nov 7; 47(3):359-64.
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      186. Mostov KE, Deitcher DL. Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA. Cell. 1986 Aug 15; 46(4):613-21.
        View in: PubMed
      187. Deitcher DL, Mostov KE. Alternate splicing of rabbit polymeric immunoglobulin receptor. Mol Cell Biol. 1986 Jul; 6(7):2712-5.
        View in: PubMed PMC367828
      188. Deitcher DL, Neutra MR, Mostov KE. Functional expression of the polymeric immunoglobulin receptor from cloned cDNA in fibroblasts. J Cell Biol. 1986 Mar; 102(3):911-9.
        View in: PubMed PMC2114126
      189. Mostov KE, Friedlander M, Blobel G. Structure and function of the receptor for polymeric immunoglobulins. Biochem Soc Symp. 1986; 51:113-5.
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      190. Mostov KE, Simister NE. Transcytosis. Cell. 1985 Dec; 43(2 Pt 1):389-90.
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      191. Mostov KE, Friedlander M, Blobel G. The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains. Nature. 1984 Mar 1-7; 308(5954):37-43.
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      192. Anderson DJ, Mostov KE, Blobel G. Mechanisms of integration of de novo-synthesized polypeptides into membranes: signal-recognition particle is required for integration into microsomal membranes of calcium ATPase and of lens MP26 but not of cytochrome b5. Proc Natl Acad Sci U S A. 1983 Dec; 80(23):7249-53.
        View in: PubMed PMC390032
      193. Mostov KE, Blobel G. Transcellular transport of polymeric immunoglobulin by secretory component: a model system for studying intracellular protein sorting. Ann N Y Acad Sci. 1983 Jun 30; 409:441-51.
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      194. Mostov KE, Blobel G. Biosynthesis, processing, and function of secretory component. Methods Enzymol. 1983; 98:458-66.
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      195. Mostov KE, Blobel G. A transmembrane precursor of secretory component. The receptor for transcellular transport of polymeric immunoglobulins. J Biol Chem. 1982 Oct 10; 257(19):11816-21.
        View in: PubMed
      196. Hemperly JJ, Mostov KE, Cunningham BA. In vitro translation and processing of a precursor form of favin, a lectin from Vicia faba. J Biol Chem. 1982 Jul 10; 257(13):7903-9.
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      197. Mostov KE, DeFoor P, Fleischer S, Blobel G. Co-translational membrane integration of calcium pump protein without signal sequence cleavage. Nature. 1981 Jul 2; 292(5818):87-8.
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      198. Mostov KE, Kraehenbuhl JP, Blobel G. Receptor-mediated transcellular transport of immunoglobulin: synthesis of secretory component as multiple and larger transmembrane forms. Proc Natl Acad Sci U S A. 1980 Dec; 77(12):7257-61.
        View in: PubMed PMC350481
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