Kenneth Feingold, MD

Title(s)Professor Emeritus, Medicine
SchoolSchool of Medicine
AddressLocation Required, #001
Phone415-750-2005
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidencySchool of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    PPARs and LXR Regulate Epidermal Differentiation
    NIH R01AR050629Aug 9, 2004 - May 31, 2008
    Role: Principal Investigator
    Effects of Psychological Stress on the Stratum Corneum
    NIH R01AR049932Apr 1, 2004 - Dec 31, 2009
    Role: Principal Investigator
    Stratum Corneum Acidification in the Neonate
    NIH R01HD029706May 15, 1994 - Apr 30, 2010
    Role: Principal Investigator
    REGULATION OF EPIDERMAL LIPID METABOLISM
    NIH R01AR039639Jan 10, 1991 - Jun 30, 2001
    Role: Principal Investigator
    Relationship of Keratinocyte Function to Differentiation
    NIH P01AR039448Jul 15, 1988 - Jul 31, 2010
    Role: Co-Investigator
    CHOLESTEROL SYNTHESIS IN DIABETIC ANIMALS
    NIH R01AM032685Jul 1, 1983 - Jun 30, 1986
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The bidirectional interaction of COVID-19 infections and lipoproteins. Best Pract Res Clin Endocrinol Metab. 2023 07; 37(4):101751. Feingold KR. PMID: 36894344; PMCID: PMC9951034.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. Recent advances in lipidology. Best Pract Res Clin Endocrinol Metab. 2023 05; 37(3):101750. Feingold KR, Chait A. PMID: 36914551.
      View in: PubMed   Mentions:    Fields:    
    3. Lipid and Lipoprotein Metabolism. Endocrinol Metab Clin North Am. 2022 09; 51(3):437-458. Feingold KR. PMID: 35963623.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    4. Approach to patients with elevated low-density lipoprotein cholesterol levels. Best Pract Res Clin Endocrinol Metab. 2023 05; 37(3):101658. Feingold KR, Chait A. PMID: 35487874.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Approach to patients with hypertriglyceridemia. Best Pract Res Clin Endocrinol Metab. 2023 05; 37(3):101659. Chait A, Feingold KR. PMID: 35459627.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. The bidirectional link between HDL and COVID-19 infections. J Lipid Res. 2021; 62:100067. Feingold KR. PMID: 33741421; PMCID: PMC7963524.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    7. Stress test of the skin: The cutaneous permeability barrier treadmill. Exp Dermatol. 2020 01; 29(1):112-113. Schmuth M, Feingold KR, Elias PM. PMID: 31682042; PMCID: PMC6989371.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Maximizing the benefits of cholesterol-lowering drugs. Curr Opin Lipidol. 2019 10; 30(5):388-394. Feingold KR. PMID: 31335331.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Going from A to Z. N Engl J Med. 2018 01 04; 378(1):73-79. Atri D, Furfaro D, Dhaliwal G, Feingold KR, Manesh R. PMID: 29298151.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines. J Invest Dermatol. 2017 06; 137(6):1277-1285. Hu L, Mauro TM, Dang E, Man G, Zhang J, Lee D, Wang G, Feingold KR, Elias PM, Man MQ. PMID: 28115059; PMCID: PMC5441930.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    11. Stressing Signal Versus Noise: An Exercise in Clinical Reasoning. J Gen Intern Med. 2017 01; 32(1):122-126. Gupta N, Feingold K, Dhaliwal G. PMID: 27798784; PMCID: PMC5215167.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Effect of inflammation on HDL structure and function. Curr Opin Lipidol. 2016 10; 27(5):521-30. Feingold KR, Grunfeld C. PMID: 27495134.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    13. Symptomatic Graves' Disease After Autoimmune Hypothyroidism. Am J Med. 2016 May; 129(5):e19-20. Brondfield S, Feingold KR. PMID: 26772649.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. High-Density Lipoprotein Subclasses and Noncardiovascular, Noncancer Chronic Inflammatory-Related Events Versus Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2015 Sep 14; 4(9):e002295. Duprez DA, Otvos J, Tracy RP, Feingold KR, Greenland P, Gross MD, Lima JA, Mackey RH, Neaton JD, Sanchez OA, Jacobs DR. PMID: 26370448; PMCID: PMC4599511.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    15. TLR3: a receptor that recognizes cell injury is essential for permeability barrier homeostasis following UV irradiation. J Invest Dermatol. 2015 Feb; 135(2):339-340. Feingold KR. PMID: 25573047.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    16. Statin myopathy: a problem looking for a solution. Atherosclerosis. 2015 Mar; 239(1):85-6. Feingold KR. PMID: 25576849.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Lowered humidity produces human epidermal equivalents with enhanced barrier properties. Tissue Eng Part C Methods. 2015 Jan; 21(1):15-22. Sun R, Celli A, Crumrine D, Hupe M, Adame LC, Pennypacker SD, Park K, Uchida Y, Feingold KR, Elias PM, Ilic D, Mauro TM. PMID: 24803151; PMCID: PMC4291214.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages. J Lipid Res. 2014 Dec; 55(12):2501-8. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. PMID: 25320346; PMCID: PMC4242443.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    19. Paradoxical benefits of psychological stress in inflammatory dermatoses models are glucocorticoid mediated. J Invest Dermatol. 2014 Dec; 134(12):2890-2897. Lin TK, Man MQ, Santiago JL, Scharschmidt TC, Hupe M, Martin-Ezquerra G, Youm JK, Zhai Y, Trullas C, Feingold KR, Elias PM. PMID: 24991965; PMCID: PMC4227540.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    20. Basis for enhanced barrier function of pigmented skin. J Invest Dermatol. 2014 Sep; 134(9):2399-2407. Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias PM. PMID: 24732399; PMCID: PMC4134407.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    21. The adverse effect of IFN gamma on stratum corneum structure and function in psoriasis and atopic dermatitis. J Invest Dermatol. 2014 Mar; 134(3):597-600. Feingold KR. PMID: 24518112.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. The important role of lipids in the epidermis and their role in the formation and maintenance of the cutaneous barrier. Biochim Biophys Acta. 2014 Mar; 1841(3):279. Feingold K, Elias P. PMID: 24564908.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    23. Capsule commentary on Radin, pitfalls in hemoglobin A1c measurement: when results may be misleading. J Gen Intern Med. 2014 Feb; 29(2):363. Feingold KR. PMID: 24065382; PMCID: PMC3912282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis. Biochim Biophys Acta. 2014 Mar; 1841(3):353-61. Elias PM, Williams ML, Choi EH, Feingold KR. PMID: 24291327; PMCID: PMC3966299.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    25. Role of lipids in the formation and maintenance of the cutaneous permeability barrier. Biochim Biophys Acta. 2014 Mar; 1841(3):280-94. Feingold KR, Elias PM. PMID: 24262790.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    26. Diabetes and risk of hospitalized fall injury among older adults. Diabetes Care. 2013 Dec; 36(12):3985-91. Yau RK, Strotmeyer ES, Resnick HE, Sellmeyer DE, Feingold KR, Cauley JA, Vittinghoff E, De Rekeneire N, Harris TB, Nevitt MC, Cummings SR, Shorr RI, Schwartz AV. PMID: 24130352; PMCID: PMC3836123.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    27. Innate immunity stimulates permeability barrier homeostasis. J Invest Dermatol. 2013 Aug; 133(8):1925-7. Feingold KR. PMID: 23856931.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Ceramides stimulate caspase-14 expression in human keratinocytes. Exp Dermatol. 2013 Feb; 22(2):113-8. Jiang YJ, Kim P, Uchida Y, Elias PM, Bikle DD, Grunfeld C, Feingold KR. PMID: 23362869; PMCID: PMC4099380.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    29. Lipids: a key player in the battle between the host and microorganisms. J Lipid Res. 2012 Dec; 53(12):2487-9. Feingold KR, Grunfeld C. PMID: 23075464; PMCID: PMC3494250.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    30. Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function. J Invest Dermatol. 2013 Feb; 133(2):469-78. Lin TK, Man MQ, Santiago JL, Park K, Roelandt T, Oda Y, Hupe M, Crumrine D, Lee HJ, Gschwandtner M, Thyssen JP, Trullas C, Tschachler E, Feingold KR, Elias PM. PMID: 23014339; PMCID: PMC3532566.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    31. Tight junction properties change during epidermis development. Exp Dermatol. 2012 Oct; 21(10):798-801. Celli A, Zhai Y, Jiang YJ, Crumrine D, Elias PM, Feingold KR, Mauro TM. PMID: 22882565; PMCID: PMC3477265.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    32. Lamellar bodies: the key to cutaneous barrier function. J Invest Dermatol. 2012 Aug; 132(8):1951-3. Feingold KR. PMID: 22797297.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    33. Mechanisms of triglyceride accumulation in activated macrophages. J Leukoc Biol. 2012 Oct; 92(4):829-39. Feingold KR, Shigenaga JK, Kazemi MR, McDonald CM, Patzek SM, Cross AS, Moser A, Grunfeld C. PMID: 22753953; PMCID: PMC3441312.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    34. Psoriasis: it's more than just the skin. J Lipid Res. 2012 Aug; 53(8):1427-9. Feingold KR, Grunfeld C. PMID: 22685321; PMCID: PMC3540839.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Regulation of permeability barrier homeostasis. Clin Dermatol. 2012 May-Jun; 30(3):263-8. Feingold KR, Denda M. PMID: 22507038.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    36. Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders. Clin Dermatol. 2012 May-Jun; 30(3):311-22. Elias PM, Williams ML, Feingold KR. PMID: 22507046; PMCID: PMC3607361.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    37. Angiopoietin like protein 4 expression is decreased in activated macrophages. Biochem Biophys Res Commun. 2012 May 11; 421(3):612-5. Feingold KR, Shigenaga JK, Cross AS, Moser A, Grunfeld C. PMID: 22538368.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    38. FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis. Endocrinology. 2012 Jun; 153(6):2689-700. Feingold KR, Grunfeld C, Heuer JG, Gupta A, Cramer M, Zhang T, Shigenaga JK, Patzek SM, Chan ZW, Moser A, Bina H, Kharitonenkov A. PMID: 22474187; PMCID: PMC3359613.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    39. Topical herbal extract (Huangdang mixture) exhibits both preventive and therapeutic effects in murine acute irritant contact dermatitis. Int J Dermatol. 2011 Nov; 50(11):1421-1427. Man W, Man M, Hupe M, Martin-Ezquerra G, Feingold KR, Elias PM, Man MQ. PMID: 22004502.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    40. Cardiolipin synthase-1 mRNA expression does not correlate with endogenous cardiolipin synthase enzyme activity in vitro and in vivo in mammalian lipopolysaccharide models of inflammation. Inflammation. 2011 Aug; 34(4):247-54. Lu B, Xu FY, Taylor WA, Feingold KR, Hatch GM. PMID: 20652826.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    41. Inflammation inhibits GPR81 expression in adipose tissue. Inflamm Res. 2011 Oct; 60(10):991-5. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. PMID: 21751047.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    42. Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis. J Invest Dermatol. 2011 Sep; 131(9):1845-52. Hatano Y, Elias PM, Crumrine D, Feingold KR, Katagiri K, Fujiwara S. PMID: 21633371; PMCID: PMC3156961.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsPHPublic Health
    43. PPARgamma activators stimulate aquaporin 3 expression in keratinocytes/epidermis. Exp Dermatol. 2011 Jul; 20(7):595-9. Jiang YJ, Kim P, Lu YF, Feingold KR. PMID: 21457357; PMCID: PMC3120929.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    44. Lipid metabolism in the epidermis. Dermatoendocrinol. 2011 Apr; 3(2):52. Feingold KR. PMID: 21695011; PMCID: PMC3117001.
      View in: PubMed   Mentions: 1  
    45. The expression and regulation of enzymes mediating the biosynthesis of triglycerides and phospholipids in keratinocytes/epidermis. Dermatoendocrinol. 2011 Apr; 3(2):70-6. Jiang YJ, Feingold KR. PMID: 21695015; PMCID: PMC3117005.
      View in: PubMed   Mentions: 7  
    46. The mechanisms by which lipids coordinately regulate the formation of the protein and lipid domains of the stratum corneum: Role of fatty acids, oxysterols, cholesterol sulfate and ceramides as signaling molecules. Dermatoendocrinol. 2011 Apr; 3(2):113-8. Feingold KR, Jiang YJ. PMID: 21695021; PMCID: PMC3117011.
      View in: PubMed   Mentions: 9  
    47. Inflammation inhibits the expression of phosphoenolpyruvate carboxykinase in liver and adipose tissue. Innate Immun. 2012 Apr; 18(2):231-40. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. PMID: 21450790.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    48. A topical Chinese herbal mixture improves epidermal permeability barrier function in normal murine skin. Exp Dermatol. 2011 Mar; 20(3):285-8. Man M, Hupe M, Mackenzie D, Kim H, Oda Y, Crumrine D, Lee SH, Martin-Ezquerra G, Trullas C, Mauro TM, Feingold KR, Elias PM, Man MQ. PMID: 21323748; PMCID: PMC4548955.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    49. The role of HDL in innate immunity. J Lipid Res. 2011 Jan; 52(1):1-3. Feingold KR, Grunfeld C. PMID: 20944062; PMCID: PMC2999920.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    50. Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis. J Lipid Res. 2010 Nov; 51(11):3207-16. Lu B, Jiang YJ, Kim P, Moser A, Elias PM, Grunfeld C, Feingold KR. PMID: 20719759; PMCID: PMC2952561.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    51. Regulation of ABCG1 expression in human keratinocytes and murine epidermis. J Lipid Res. 2010 Nov; 51(11):3185-95. Jiang YJ, Lu B, Tarling EJ, Kim P, Man MQ, Crumrine D, Edwards PA, Elias PM, Feingold KR. PMID: 20675829; PMCID: PMC2952559.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    52. IL-6 stimulates but is not essential for stratum corneum formation and permeability barrier development during gestation. Exp Dermatol. 2010 Aug; 19(8):e31-6. Jiang YJ, Lu B, Crumrine D, Elias PM, Feingold KR. PMID: 19758319.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    53. Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification? J Invest Dermatol. 2010 Aug; 130(8):2141-4. Fluhr JW, Elias PM, Man MQ, Hupe M, Selden C, Sundberg JP, Tschachler E, Eckhart L, Mauro TM, Feingold KR. PMID: 20376063; PMCID: PMC4548931.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    54. Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes. Innate Immun. 2011 Apr; 17(2):174-82. Feingold KR, Shigenaga JK, Patzek SM, Chui LG, Moser A, Grunfeld C. PMID: 20100709.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    55. The acute phase response inhibits reverse cholesterol transport. J Lipid Res. 2010 Apr; 51(4):682-4. Feingold KR, Grunfeld C. PMID: 20071695; PMCID: PMC2842157.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    56. The acute phase response stimulates the expression of angiopoietin like protein 4. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1737-41. Lu B, Moser A, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 20043872.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    57. Does inhibition of apolipoprotein B synthesis produce foie gras? J Lipid Res. 2010 May; 51(5):877-8. Feingold KR. PMID: 20042543; PMCID: PMC2853454.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    58. Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators. J Allergy Clin Immunol. 2010 Jan; 125(1):160-9.e1-5. Hatano Y, Man MQ, Uchida Y, Crumrine D, Mauro TM, Feingold KR, Elias PM, Holleran WM. PMID: 19818482; PMCID: PMC2859962.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    59. Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes. J Invest Dermatol. 2010 Feb; 130(2):500-10. Hachem JP, Roelandt T, Schürer N, Pu X, Fluhr J, Giddelo C, Man MQ, Crumrine D, Roseeuw D, Feingold KR, Mauro T, Elias PM. PMID: 19741713; PMCID: PMC2844116.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    60. ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists. Atherosclerosis. 2010 Mar; 209(1):81-8. Feingold KR, Kazemi MR, Magra AL, McDonald CM, Chui LG, Shigenaga JK, Patzek SM, Chan ZW, Londos C, Grunfeld C. PMID: 19748622.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    61. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. J Allergy Clin Immunol. 2009 Sep; 124(3):496-506, 506.e1-6. Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM. PMID: 19733297; PMCID: PMC2881668.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    62. PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. J Invest Dermatol. 2010 Feb; 130(2):511-9. Jiang YJ, Barish G, Lu B, Evans RM, Crumrine D, Schmuth M, Elias PM, Feingold KR. PMID: 19675577.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    63. Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm. J Lipid Res. 2009 Oct; 50(10):2055-63. Feingold KR, Moser A, Patzek SM, Shigenaga JK, Grunfeld C. PMID: 19443862; PMCID: PMC2739760.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    64. Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes. J Biol Chem. 2009 Jul 10; 284(28):18942-52. Jiang YJ, Uchida Y, Lu B, Kim P, Mao C, Akiyama M, Elias PM, Holleran WM, Grunfeld C, Feingold KR. PMID: 19429679; PMCID: PMC2707228.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    65. Pentosidine and increased fracture risk in older adults with type 2 diabetes. J Clin Endocrinol Metab. 2009 Jul; 94(7):2380-6. Schwartz AV, Garnero P, Hillier TA, Sellmeyer DE, Strotmeyer ES, Feingold KR, Resnick HE, Tylavsky FA, Black DM, Cummings SR, Harris TB, Bauer DC, Health, Aging, and Body Composition Study. PMID: 19383780; PMCID: PMC2708944.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    66. The role of CD44 in cutaneous inflammation. Exp Dermatol. 2009 Nov; 18(11):962-8. Man M, Elias PM, Man W, Wu Y, Bourguignon LY, Feingold KR, Man MQ. PMID: 19469887; PMCID: PMC2784008.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    67. Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis. Exp Dermatol. 2009 Jul; 18(7):643-9. Demerjian M, Choi EH, Man MQ, Chang S, Elias PM, Feingold KR. PMID: 19236478; PMCID: PMC2704255.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    68. IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development. J Dermatol Sci. 2009 May; 54(2):88-98. Jiang YJ, Lu B, Crumrine D, Man MQ, Elias PM, Feingold KR. PMID: 19216058.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    69. pH-regulated mechanisms account for pigment-type differences in epidermal barrier function. J Invest Dermatol. 2009 Jul; 129(7):1719-29. Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, Sirimanna G, Feingold KR, Mauro TM, Elias PM. PMID: 19177137; PMCID: PMC2695842.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    70. Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis. J Invest Dermatol. 2009 Jul; 129(7):1824-35. Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, Holleran WM. PMID: 19177139; PMCID: PMC2695850.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    71. The "caveolae brake hypothesis" and the epidermal barrier. J Invest Dermatol. 2009 Apr; 129(4):927-36. Roelandt T, Giddelo C, Heughebaert C, Denecker G, Hupe M, Crumrine D, Kusuma A, Haftek M, Roseeuw D, Declercq W, Feingold KR, Elias PM, Hachem JP. PMID: 19005485.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    72. The outer frontier: the importance of lipid metabolism in the skin. J Lipid Res. 2009 Apr; 50 Suppl:S417-22. Feingold KR. PMID: 18980941; PMCID: PMC2674689.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    73. Endotoxin in the gut and chylomicrons: translocation or transportation? J Lipid Res. 2009 Jan; 50(1):1-2. Grunfeld C, Feingold KR. PMID: 18957696.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    74. LPS and proinflammatory cytokines decrease lipin-1 in mouse adipose tissue and 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2008 Dec; 295(6):E1502-9. Lu B, Lu Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 18940942; PMCID: PMC2603550.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    75. Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification. J Invest Dermatol. 2009 Feb; 129(2):365-74. Fluhr JW, Man MQ, Hachem JP, Crumrine D, Mauro TM, Elias PM, Feingold KR. PMID: 18704104; PMCID: PMC4548956.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    76. Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis. Am J Pathol. 2008 Sep; 173(3):689-99. Elias PM, Arbiser J, Brown BE, Rossiter H, Man MQ, Cerimele F, Crumrine D, Gunathilake R, Choi EH, Uchida Y, Tschachler E, Feingold KR. PMID: 18688025; PMCID: PMC2527083.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    77. Inflammation stimulates the expression of PCSK9. Biochem Biophys Res Commun. 2008 Sep 19; 374(2):341-4. Feingold KR, Moser AH, Shigenaga JK, Patzek SM, Grunfeld C. PMID: 18638454; PMCID: PMC2571081.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    78. LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney. J Lipid Res. 2008 Oct; 49(10):2179-87. Feingold KR, Wang Y, Moser A, Shigenaga JK, Grunfeld C. PMID: 18574256; PMCID: PMC2533407.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    79. Skin as an endocrine organ: implications for its function. Drug Discov Today Dis Mech. 2008 Jun 01; 5(2):137-144. Slominski A, Wortsman J, Paus R, Elias PM, Tobin DJ, Feingold KR. PMID: 19492070; PMCID: PMC2658605.
      View in: PubMed   Mentions: 45  
    80. HDL and innate immunity: a tale of two apolipoproteins. J Lipid Res. 2008 Aug; 49(8):1605-6. Grunfeld C, Feingold KR. PMID: 18515886.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    81. Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models. Exp Dermatol. 2008 Aug; 17(8):681-7. Man MQ, Shi Y, Man M, Lee SH, Demerjian M, Chang S, Feingold KR, Elias PM. PMID: 18341576; PMCID: PMC2843409.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    82. Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology. J Lipid Res. 2008 Mar; 49(3):499-509. Schmuth M, Jiang YJ, Dubrac S, Elias PM, Feingold KR. PMID: 18182682.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    83. Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2. Am J Pathol. 2008 Jan; 172(1):86-97. Demerjian M, Hachem JP, Tschachler E, Denecker G, Declercq W, Vandenabeele P, Mauro T, Hupe M, Crumrine D, Roelandt T, Houben E, Elias PM, Feingold KR. PMID: 18156206; PMCID: PMC2189608.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    84. Diabetes-related complications, glycemic control, and falls in older adults. Diabetes Care. 2008 Mar; 31(3):391-6. Schwartz AV, Vittinghoff E, Sellmeyer DE, Feingold KR, de Rekeneire N, Strotmeyer ES, Shorr RI, Vinik AI, Odden MC, Park SW, Faulkner KA, Harris TB, Health, Aging, and Body Composition Study. PMID: 18056893; PMCID: PMC2288549.
      View in: PubMed   Mentions: 159     Fields:    Translation:Humans
    85. Infection and inflammation decrease apolipoprotein M expression. Atherosclerosis. 2008 Jul; 199(1):19-26. Feingold KR, Shigenaga JK, Chui LG, Moser A, Khovidhunkit W, Grunfeld C. PMID: 18054359.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    86. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest. 2007 Nov; 117(11):3339-49. Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. PMID: 17975669; PMCID: PMC2045593.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    87. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol. 2008 Apr; 128(4):917-25. Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, Elias PM. PMID: 17943185; PMCID: PMC2671223.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    88. Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis. J Lipid Res. 2007 Dec; 48(12):2531-46. Feingold KR. PMID: 17872588.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    89. Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. J Invest Dermatol. 2008 Feb; 128(2):370-7. Man MQ, Barish GD, Schmuth M, Crumrine D, Barak Y, Chang S, Jiang Y, Evans RM, Elias PM, Feingold KR. PMID: 17713572.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    90. Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol. 2008 Jan; 128(1):79-86. Man MQ, Hatano Y, Lee SH, Man M, Chang S, Feingold KR, Leung DY, Holleran W, Uchida Y, Elias PM. PMID: 17671515; PMCID: PMC2671229.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    91. PPAR and LXR activators regulate ABCA12 expression in human keratinocytes. J Invest Dermatol. 2008 Jan; 128(1):104-9. Jiang YJ, Lu B, Kim P, Paragh G, Schmitz G, Elias PM, Feingold KR. PMID: 17611579.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    92. The regulation of permeability barrier homeostasis. J Invest Dermatol. 2007 Jul; 127(7):1574-6. Feingold KR, Schmuth M, Elias PM. PMID: 17568800.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    93. Stratum corneum acidification is impaired in moderately aged human and murine skin. J Invest Dermatol. 2007 Dec; 127(12):2847-56. Choi EH, Man MQ, Xu P, Xin S, Liu Z, Crumrine DA, Jiang YJ, Fluhr JW, Feingold KR, Elias PM, Mauro TM. PMID: 17554364.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    94. Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization. Am J Pathol. 2007 Jun; 170(6):2055-67. Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, Mauro TM. PMID: 17525272; PMCID: PMC1899430.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    95. Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response. Biochim Biophys Acta. 2007 Sep; 1771(9):1177-85. Lu B, Sims PJ, Wiedmer T, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 17590392.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    96. Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Metabolism. 2007 Feb; 56(2):267-79. Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR. PMID: 17224343; PMCID: PMC2700944.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    97. Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells. Biochem J. 2007 Jan 01; 401(1):103-9. Van Q, Liu J, Lu B, Feingold KR, Shi Y, Lee RM, Hatch GM. PMID: 16939411; PMCID: PMC1698660.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    98. Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins. J Lipid Res. 2006 Nov; 47(11):2575-80. Staprans I, Pan XM, Rapp JH, Moser AH, Feingold KR. PMID: 16894239.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    99. Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function. Am J Physiol Regul Integr Comp Physiol. 2006 Dec; 291(6):R1657-62. Choi EH, Demerjian M, Crumrine D, Brown BE, Mauro T, Elias PM, Feingold KR. PMID: 16857896.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    100. Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response. J Lipid Res. 2006 Oct; 47(10):2179-90. Lu B, Moser AH, Shigenaga JK, Feingold KR, Grunfeld C. PMID: 16847310.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    101. Regulation of ABCA1 expression in human keratinocytes and murine epidermis. J Lipid Res. 2006 Oct; 47(10):2248-58. Jiang YJ, Lu B, Kim P, Elias PM, Feingold KR. PMID: 16825673.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    102. Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models. Exp Dermatol. 2006 Jul; 15(7):483-92. Fluhr JW, Feingold KR, Elias PM. PMID: 16761956.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    103. Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formation/secretion, and permeability barrier homeostasis. J Invest Dermatol. 2006 Jun; 126(6):1356-65. Bourguignon LY, Ramez M, Gilad E, Singleton PA, Man MQ, Crumrine DA, Elias PM, Feingold KR. PMID: 16557236.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    104. Serine protease signaling of epidermal permeability barrier homeostasis. J Invest Dermatol. 2006 Sep; 126(9):2074-86. Hachem JP, Houben E, Crumrine D, Man MQ, Schurer N, Roelandt T, Choi EH, Uchida Y, Brown BE, Feingold KR, Elias PM. PMID: 16691196.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    105. FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Mol Cell Biol. 2006 May; 26(9):3455-67. Wu Q, Ortegon AM, Tsang B, Doege H, Feingold KR, Stahl A. PMID: 16611988; PMCID: PMC1447434.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    106. Thiazolidinedione use and bone loss in older diabetic adults. J Clin Endocrinol Metab. 2006 Sep; 91(9):3349-54. Schwartz AV, Sellmeyer DE, Vittinghoff E, Palermo L, Lecka-Czernik B, Feingold KR, Strotmeyer ES, Resnick HE, Carbone L, Beamer BA, Park SW, Lane NE, Harris TB, Cummings SR. PMID: 16608888; PMCID: PMC1563497.
      View in: PubMed   Mentions: 158     Fields:    Translation:Humans
    107. Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome. J Invest Dermatol. 2006 Jul; 126(7):1609-21. Hachem JP, Wagberg F, Schmuth M, Crumrine D, Lissens W, Jayakumar A, Houben E, Mauro TM, Leonardsson G, Brattsand M, Egelrud T, Roseeuw D, Clayman GL, Feingold KR, Williams ML, Elias PM. PMID: 16601670.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    108. Cloning and characterization of a cDNA encoding human cardiolipin synthase (hCLS1). J Lipid Res. 2006 Jun; 47(6):1140-5. Lu B, Xu FY, Jiang YJ, Choy PC, Hatch GM, Grunfeld C, Feingold KR. PMID: 16547353.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    109. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Exp Dermatol. 2006 Mar; 15(3):154-60. Demerjian M, Man MQ, Choi EH, Brown BE, Crumrine D, Chang S, Mauro T, Elias PM, Feingold KR. PMID: 16480422.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    110. Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing. J Invest Dermatol. 2006 Feb; 126(2):386-92. Man MQ, Choi EH, Schmuth M, Crumrine D, Uchida Y, Elias PM, Holleran WM, Feingold KR. PMID: 16374473.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    111. Decreased nuclear hormone receptor expression in the livers of mice in late pregnancy. Am J Physiol Endocrinol Metab. 2006 Jun; 290(6):E1313-20. Sweeney TR, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 16434558.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    112. Differential expression of fatty acid transport proteins in epidermis and skin appendages. J Invest Dermatol. 2005 Dec; 125(6):1174-81. Schmuth M, Ortegon AM, Mao-Qiang M, Elias PM, Feingold KR, Stahl A. PMID: 16354187.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    113. Topical liver x receptor activators accelerate postnatal acidification of stratum corneum and improve function in the neonate. J Invest Dermatol. 2005 Dec; 125(6):1206-14. Fluhr JW, Crumrine D, Mao-Qiang M, Moskowitz DG, Elias PM, Feingold KR. PMID: 16354191.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    114. The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis. Mol Nutr Food Res. 2005 Nov; 49(11):1075-82. Staprans I, Pan XM, Rapp JH, Feingold KR. PMID: 16270280.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    115. Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis. J Lipid Res. 2005 Nov; 46(11):2448-57. Lu B, Jiang YJ, Man MQ, Brown B, Elias PM, Feingold KR. PMID: 16150824.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    116. LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes. J Lipid Res. 2005 Dec; 46(12):2657-66. Jiang YJ, Kim P, Elias PM, Feingold KR. PMID: 16150827.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    117. Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. J Invest Dermatol. 2005 Sep; 125(3):510-20. Hachem JP, Man MQ, Crumrine D, Uchida Y, Brown BE, Rogiers V, Roseeuw D, Feingold KR, Elias PM. PMID: 16117792.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    118. Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines. J Lipid Res. 2005 Nov; 46(11):2377-87. Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 16106051.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    119. Suppression of estrogen-related receptor alpha and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response. J Lipid Res. 2005 Oct; 46(10):2282-8. Kim MS, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. PMID: 16061943.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    120. Is endogenous glycerol a determinant of stratum corneum hydration in humans? J Invest Dermatol. 2005 Aug; 125(2):288-93. Choi EH, Man MQ, Wang F, Zhang X, Brown BE, Feingold KR, Elias PM. PMID: 16098039.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    121. Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity. J Invest Dermatol. 2005 Mar; 124(3):587-95. Choi EH, Brown BE, Crumrine D, Chang S, Man MQ, Elias PM, Feingold KR. PMID: 15737200.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    122. Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists. Arterioscler Thromb Vasc Biol. 2005 Jun; 25(6):1220-4. Kazemi MR, McDonald CM, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 15705927.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    123. Parotid secretory protein is an HDL-associated protein with anticandidal activity. Am J Physiol Regul Integr Comp Physiol. 2005 May; 288(5):R1306-15. Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane JP, Feingold KR, Grunfeld C. PMID: 15637169.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    124. Diabetes and bone loss at the hip in older black and white adults. J Bone Miner Res. 2005 Apr; 20(4):596-603. Schwartz AV, Sellmeyer DE, Strotmeyer ES, Tylavsky FA, Feingold KR, Resnick HE, Shorr RI, Nevitt MC, Black DM, Cauley JA, Cummings SR, Harris TB, Health ABC Study. PMID: 15765178.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    125. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. J Invest Dermatol. 2004 Sep; 123(3):603-6. Presland RB, Coulombe PA, Eckert RL, Mao-Qiang M, Feingold KR, Elias PM. PMID: 15304104.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    126. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Atherosclerosis. 2004 Sep; 176(1):37-44. Khovidhunkit W, Duchateau PN, Medzihradszky KF, Moser AH, Naya-Vigne J, Shigenaga JK, Kane JP, Grunfeld C, Feingold KR. PMID: 15306172.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    127. Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. J Invest Dermatol. 2004 Aug; 123(2):305-12. Mao-Qiang M, Fowler AJ, Schmuth M, Lau P, Chang S, Brown BE, Moser AH, Michalik L, Desvergne B, Wahli W, Li M, Metzger D, Chambon PH, Elias PM, Feingold KR. PMID: 15245430.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    128. Functional consequences of a neutral pH in neonatal rat stratum corneum. J Invest Dermatol. 2004 Jul; 123(1):140-51. Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M, Haftek M, Serre G, Crumrine D, Mauro TM, Elias PM, Feingold KR. PMID: 15191554.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    129. The effect of LXR activators on AP-1 proteins in keratinocytes. J Invest Dermatol. 2004 Jul; 123(1):41-8. Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR. PMID: 15191540.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    130. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. Am J Physiol Endocrinol Metab. 2004 Oct; 287(4):E731-8. Kim MS, Shigenaga J, Moser A, Grunfeld C, Feingold KR. PMID: 15198932.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    131. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res. 2004 Jul; 45(7):1169-96. Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. PMID: 15102878.
      View in: PubMed   Mentions: 519     Fields:    Translation:HumansAnimals
    132. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. J Invest Dermatol. 2004 Apr; 122(4):971-83. Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, Chambon P, Willson TM, Elias PM, Feingold KR. PMID: 15102088.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    133. Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis). J Invest Dermatol. 2004 Apr; 122(4):909-22. Schmuth M, Fluhr JW, Crumrine DC, Uchida Y, Hachem JP, Behne M, Moskowitz DG, Christiano AM, Feingold KR, Elias PM. PMID: 15102081.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    134. Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E201-7. Feingold K, Kim MS, Shigenaga J, Moser A, Grunfeld C. PMID: 14701665.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    135. Basis for abnormal desquamation and permeability barrier dysfunction in RXLI. J Invest Dermatol. 2004 Feb; 122(2):314-9. Elias PM, Crumrine D, Rassner U, Hachem JP, Menon GK, Man W, Choy MH, Leypoldt L, Feingold KR, Williams ML. PMID: 15009711.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    136. Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum. J Invest Dermatol. 2004 Feb; 122(2):320-9. Fluhr JW, Behne MJ, Brown BE, Moskowitz DG, Selden C, Mao-Qiang M, Mauro TM, Elias PM, Feingold KR. PMID: 15009712.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    137. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J Biol Chem. 2004 Mar 19; 279(12):11767-76. Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV. PMID: 14668353.
      View in: PubMed   Mentions: 221     Fields:    Translation:AnimalsCells
    138. pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion. J Invest Dermatol. 2003 Aug; 121(2):345-53. Hachem JP, Crumrine D, Fluhr J, Brown BE, Feingold KR, Elias PM. PMID: 12880427.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    139. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. J Lipid Res. 2003 Sep; 44(9):1728-36. Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. PMID: 12777468.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    140. Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol. 2003 Jun; 120(6):998-1006. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM. PMID: 12787127.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    141. [Beyond glucocorticoids, retinoids and vitamin D--the evolution of nuclear hormone type transcription factor targeting in the skin]. J Dtsch Dermatol Ges. 2003 May; 1(5):352-62. Schmuth M, Elias PM, Feingold KR. PMID: 16285300.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    142. Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice. J Invest Dermatol. 2003 May; 120(5):728-37. Fluhr JW, Mao-Qiang M, Brown BE, Wertz PW, Crumrine D, Sundberg JP, Feingold KR, Elias PM. PMID: 12713573.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    143. Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities. J Invest Dermatol. 2003 Mar; 120(3):456-64. Kao JS, Fluhr JW, Man MQ, Fowler AJ, Hachem JP, Crumrine D, Ahn SK, Brown BE, Elias PM, Feingold KR. PMID: 12603860.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    144. Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. J Lipid Res. 2003 Apr; 44(4):705-15. Staprans I, Pan XM, Rapp JH, Feingold KR. PMID: 12562864.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    145. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J Invest Dermatol. 2003 Feb; 120(2):246-55. Fowler AJ, Sheu MY, Schmuth M, Kao J, Fluhr JW, Rhein L, Collins JL, Willson TM, Mangelsdorf DJ, Elias PM, Feingold KR. PMID: 12542530.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    146. Repression of farnesoid X receptor during the acute phase response. J Biol Chem. 2003 Mar 14; 278(11):8988-95. Kim MS, Shigenaga J, Moser A, Feingold K, Grunfeld C. PMID: 12519762.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    147. Origin of the epidermal calcium gradient: regulation by barrier status and role of active vs passive mechanisms. J Invest Dermatol. 2002 Dec; 119(6):1269-74. Elias P, Ahn S, Brown B, Crumrine D, Feingold KR. PMID: 12485427.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    148. Role of peroxisome proliferator-activated receptor alpha in epidermal development in utero. J Invest Dermatol. 2002 Dec; 119(6):1298-303. Schmuth M, Schoonjans K, Yu QC, Fluhr JW, Crumrine D, Hachem JP, Lau P, Auwerx J, Elias PM, Feingold KR. PMID: 12485431.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    149. The potential of metabolic interventions to enhance transdermal drug delivery. J Investig Dermatol Symp Proc. 2002 Dec; 7(1):79-85. Elias PM, Tsai J, Menon GK, Holleran WM, Feingold KR. PMID: 12518797.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    150. The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3. J Invest Dermatol. 2002 Nov; 119(5):1109-13. Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z. PMID: 12445200.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    151. Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice. Biochem Biophys Res Commun. 2002 Jul 12; 295(2):249-54. Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott LH. PMID: 12150939.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    152. Basis for the permeability barrier abnormality in lamellar ichthyosis. Exp Dermatol. 2002 Jun; 11(3):248-56. Elias PM, Schmuth M, Uchida Y, Rice RH, Behne M, Crumrine D, Feingold KR, Holleran WM, Pharm D. PMID: 12102664.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    153. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. J Invest Dermatol. 2002 Jan; 118(1):25-34. Kömüves LG, Schmuth M, Fowler AJ, Elias PM, Hanley K, Man MQ, Moser AH, Lobaccaro JM, Williams ML, Mangelsdorf DJ, Feingold KR. PMID: 11851872.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    154. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. J Invest Dermatol. 2002 Jan; 118(1):94-101. Sheu MY, Fowler AJ, Kao J, Schmuth M, Schoonjans K, Auwerx J, Fluhr JW, Man MQ, Elias PM, Feingold KR. PMID: 11851881.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    155. Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements. J Biol Chem. 2002 Jan 25; 277(4):2916-22. Tsuruoka H, Khovidhunkit W, Brown BE, Fluhr JW, Elias PM, Feingold KR. PMID: 11707442.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
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