Kirsten Kangelaris, MD
|School||UCSF School of Medicine|
|University of California, San Francisco||M.A.S. in Clinical Research||2010|| Graduate Division (Advance Training in Clinical Research)|
Dr. Kangelaris is a hospitalist committed to improving the care of hospitalized adults. Her clinical work includes caring for medical patients on the teaching service at Moffitt-Long hospital and serving as a medical consultant on the inpatient Neurosurgical Surgery service.
Her research focuses on the role of neutrophils in the development of organ dysfunction in sepsis. Specifically, she studies clinical cohorts of patients with sepsis and the Acute Respiratory Distress Syndrome (ARDS), a common complication of sepsis, using biological markers including genomic, transcriptional and protein biomarkers in order to understand the biological underpinnings of the host response to sepsis and it's complications. The goal of this work is to identify different biological subtypes of risk that can be used to improve treatments and risk stratification in sepsis and ARDS. She is also committed to understanding the epidemiology of early critical illness and expanding cohorts to include non-intensive care unit patients in order to enhance understanding of spectrum of illness in sepsis. Another specific focus relates to understanding genetic and biologic determinants of ARDS observed in African American patients, who suffer increased acute lung injury incidence and mortality.
Dr. Kangelaris is currently supported by an NHLBI K23 to study chemokine-related pathways of ARDS pathogenesis in African-American patients. She completed medical school, internship and residency in Internal Medicine at the University of Michigan Medical School, and completed a General Medicine Research Fellowship and a Master's of Advanced Studies in Clinical Research at UCSF. She joined faculty in the Division of Hospital Medicine at UCSF in 2010. She is a Fellow of the Society of Hospital Medicine and member of the American Thoracic Society.
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