Laura Caboni, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentBiochemistry and Biophysics
Address600 16th St
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kapoor K, Finer-Moore JS, Pedersen BP, Caboni L, Waight A, Hillig RC, Bringmann P, Heisler I, Müller T, Siebeneicher H, Stroud RM. Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4711-6. PMID: 27078104.
      View in: PubMed
    2. Suzawa M, Miranda DA, Ramos KA, Ang KK, Faivre EJ, Wilson CG, Caboni L, Arkin MR, Kim YS, Fletterick RJ, Diaz A, Schneekloth JS, Ingraham HA. A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver. Elife. 2015; 4. PMID: 26653140.
      View in: PubMed
    3. Hayashi Y, Caboni L, Das D, Yumoto F, Clayton T, Deller MC, Nguyen P, Farr CL, Chiu HJ, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Tomoda K, Conklin BR, Wilson IA, Yamanaka S, Fletterick RJ. Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc Natl Acad Sci U S A. 2015 Apr 14; 112(15):4666-71. PMID: 25825768; PMCID: PMC4403148.
    4. O'Boyle NM, Pollock JK, Carr M, Knox AJ, Nathwani SM, Wang S, Caboni L, Zisterer DM, Meegan MJ. ß-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand. J Med Chem. 2014 Nov 26; 57(22):9370-82. PMID: 25369367.
      View in: PubMed
    5. Caboni L, Gálvez-Llompart M, Gálvez J, Blanco F, Rubio-Martinez J, Fayne D, Lloyd DG. Molecular topology applied to the discovery of 1-benzyl-2-(3-fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2H-pyrrole-5-one as a non-ligand-binding-pocket antiandrogen. J Chem Inf Model. 2014 Oct 27; 54(10):2953-66. PMID: 25233256.
      View in: PubMed
    6. Kesel AJ, Huang Z, Murray MG, Prichard MN, Caboni L, Nevin DK, Fayne D, Lloyd DG, Detorio MA, Schinazi RF. Retinazone inhibits certain blood-borne human viruses including Ebola virus Zaire. Antivir Chem Chemother. 2014; 23(5):197-215. PMID: 23636868.
      View in: PubMed
    7. Caboni L, Egan B, Kelly B, Blanco F, Fayne D, Meegan MJ, Lloyd DG. Structure-activity relationships in non-ligand binding pocket (non-LBP) diarylhydrazide antiandrogens. J Chem Inf Model. 2013 Aug 26; 53(8):2116-30. PMID: 23834240.
      View in: PubMed
    8. Caboni L, Lloyd DG. Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors. Med Res Rev. 2013 Sep; 33(5):1081-118. PMID: 23344935.
      View in: PubMed
    9. Blanco F, Egan B, Caboni L, Elguero J, O'Brien J, McCabe T, Fayne D, Meegan MJ, Lloyd DG. Study of E/Z isomerization in a series of novel non-ligand binding pocket androgen receptor antagonists. J Chem Inf Model. 2012 Sep 24; 52(9):2387-97. PMID: 22853713.
      View in: PubMed
    10. McKay PB, Fayne D, Horn HW, James T, Peters MB, Carta G, Caboni L, Nevin DK, Price T, Bradley G, Williams DC, Rice JE, Lloyd DG. Consensus Computational Ligand-Based Design for the Identification of Novel Modulators of Human Estrogen Receptor Alpha. Mol Inform. 2012 Apr; 31(3-4):246-58. PMID: 27477095.
      View in: PubMed
    11. Caboni L, Kinsella GK, Blanco F, Fayne D, Jagoe WN, Carr M, Williams DC, Meegan MJ, Lloyd DG. "True" antiandrogens-selective non-ligand-binding pocket disruptors of androgen receptor-coactivator interactions: novel tools for prostate cancer. J Med Chem. 2012 Feb 23; 55(4):1635-44. PMID: 22280402; PMCID: PMC3295204.
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