Leslie is the Director of the Research Technology (RT) Program and the Chief Information Officer at the Clinical and Translational Science Institute (CTSI) at UCSF. In this position, she is responsible for a team of professionals who manage, develop, and innovate on technology / infrastructure projects that support CTSI's mission to accelerate translational research. UCSF Profiles (profiles.ucsf.edu) and UCSF Clinical Trials (clinicaltrials.ucsf.edu) are among the software platforms the RT team currently manages.

Prior to the position at UCSF, Leslie served as Vice President, Product Management and Member Services at Medem Inc. After earning a Master of Public Health degree in Epidemiology from UC Berkeley, Ms. Yuan began her career as a statistical programmer, first for the California Department of Health Services and later for Syntex Corp. She spent the next 10 years at Chevron, first conducting epidemiologic research on the health effects of working in the petroleum industry, and later in Human Resources, where she was responsible for designing and planning the benefits for Chevron's self-insured and fully-insured health care plans. Ms. Yuan has served on the board of directors of a San Francisco non-profit agency, which provides support for women and children who are victims of domestic violence. She received her undergraduate degree in biology from Cornell University.