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    Liang Ge, PhD

    TitleAssistant Professor of Surgery
    SchoolUCSF School of Medicine
    DepartmentSurgery
    Address4150 Clement Street
    San Francisco CA 94121
    Phone415-221-4810
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Mookhoek A, Krishnan K, Chitsaz S, Kuang H, Ge L, Schoof PH, Bogers AJ, Takkenberg JJ, Tseng EE. Biomechanics of Failed Pulmonary Autografts Compared to Native Aortic Roots. Ann Thorac Surg. 2016 Oct 17. PMID: 27765169.
        View in: PubMed
      2. Morgan AE, Wozniak CJ, Gulati S, Ge L, Grossi EA, Weinsaft JW, Ratcliffe MB. Association of Uneven MitraClip Application and Leaflet Stress in a Finite Element Model. JAMA Surg. 2016 Oct 5. PMID: 27706490.
        View in: PubMed
      3. Pantoja JL, Morgan AE, Grossi EA, Jensen MO, Weinsaft JW, Levine RA, Ge L, Ratcliffe MB. Undersized Mitral Annuloplasty Increases Strain in the Proximal Lateral Left Ventricular Wall. Ann Thorac Surg. 2016 Oct 5. PMID: 27720201.
        View in: PubMed
      4. Vahidkhah K, Cordasco D, Abbasi M, Ge L, Tseng E, Bagchi P, Azadani AN. Flow-Induced Damage to Blood Cells in Aortic Valve Stenosis. Ann Biomed Eng. 2016 Sep; 44(9):2724-36. PMID: 27048168.
        View in: PubMed
      5. Ge L, Wu Y, Soleimani M, Khazalpour M, Takaba K, Tartibi M, Zhang Z, Acevedo-Bolton G, Saloner DA, Wallace AW, Mishra R, Grossi EA, Guccione JM, Ratcliffe MB. Moderate Ischemic Mitral Regurgitation After Posterolateral Myocardial Infarction in Sheep Alters Left Ventricular Shear but Not Normal Strain in the Infarct and Infarct Borderzone. Ann Thorac Surg. 2016 May; 101(5):1691-9. PMID: 26857634.
        View in: PubMed
      6. Morgan AE, Pantoja JL, Weinsaft J, Grossi E, Guccione J, Ge L, Ratcliffe MB. Finite Element Modeling of Mitral Valve Repair. J Biomech Eng. 2016 Feb 1; 138(2). PMID: 26632260.
        View in: PubMed
      7. Pantoja JL, Zhang Z, Tartibi M, Sun K, Macmillan W, Guccione JM, Ge L, Ratcliffe MB. Residual Stress Impairs Pump Function After Surgical Ventricular Remodeling: A Finite Element Analysis. Ann Thorac Surg. 2015 Dec; 100(6):2198-205. PMID: 26341601.
        View in: PubMed
      8. Genet M, Chuan Lee L, Ge L, Acevedo-Bolton G, Jeung N, Martin A, Cambronero N, Boyle A, Yeghiazarians Y, Kozerke S, Guccione JM. A Novel Method for Quantifying Smooth Regional Variations in Myocardial Contractility Within an Infarcted Human Left Ventricle Based on Delay-Enhanced Magnetic Resonance Imaging. J Biomech Eng. 2015 Aug; 137(8):081009. PMID: 25994000; PMCID: PMC4476031 [Available on 08/01/16].
      9. Ratcliffe M, Cambronero N, Takaba K, Ge L. Studies on postinfarct left ventricular remodeling: state of the art. Ann Thorac Surg. 2015 Mar; 99(3):755-6. PMID: 25742811.
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      10. Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB. Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation. J Heart Valve Dis. 2014 Nov; 23(6):727-34. PMID: 25790620.
        View in: PubMed
      11. Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB. Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis. Ann Thorac Surg. 2014 Oct; 98(4):1355-62. PMID: 25130075.
        View in: PubMed
      12. Genet M, Lee LC, Nguyen R, Haraldsson H, Acevedo-Bolton G, Zhang Z, Ge L, Ordovas K, Kozerke S, Guccione JM. Distribution of normal human left ventricular myofiber stress at end diastole and end systole: a target for in silico design of heart failure treatments. J Appl Physiol (1985). 2014 Jul 15; 117(2):142-52. PMID: 24876359; PMCID: PMC4101610.
      13. Lee LC, Ge L, Zhang Z, Pease M, Nikolic SD, Mishra R, Ratcliffe MB, Guccione JM. Patient-specific finite element modeling of the Cardiokinetix Parachute(®) device: effects on left ventricular wall stress and function. Med Biol Eng Comput. 2014 Jun; 52(6):557-66. PMID: 24793158; PMCID: PMC4118670.
      14. Wisneski AD, Matthews PB, Azadani AN, Mookhoek A, Chitsaz S, Guccione JM, Ge L, Tseng EE. Human pulmonary autograft wall stress at systemic pressures prior to remodeling after the Ross procedure. J Heart Valve Dis. 2014 May; 23(3):377-84. PMID: 25296465.
        View in: PubMed
      15. Lee LC, Genet M, Dang AB, Ge L, Guccione JM, Ratcliffe MB. Applications of computational modeling in cardiac surgery. J Card Surg. 2014 May; 29(3):293-302. PMID: 24708036; PMCID: PMC4045706.
      16. Ge L, Morrel WG, Ward A, Mishra R, Zhang Z, Guccione JM, Grossi EA, Ratcliffe MB. Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation. Ann Thorac Surg. 2014 May; 97(5):1496-503. PMID: 24630767; PMCID: PMC4121378.
      17. Haraldsson H, Hope M, Acevedo-Bolton G, Tseng E, Zhong X, Epstein FH, Ge L, Saloner D. Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2014; 16:6. PMID: 24400865; PMCID: PMC3895850.
      18. Ge L, Tseng EE. Invited commentary. Ann Thorac Surg. 2013 Dec; 96(6):2154. PMID: 24296184.
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      19. Azadani AN, Chitsaz S, Mannion A, Mookhoek A, Wisneski A, Guccione JM, Hope MD, Ge L, Tseng EE. Biomechanical properties of human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2013 Jul; 96(1):50-8. PMID: 23731613.
        View in: PubMed
      20. Lee LC, Wenk JF, Zhong L, Klepach D, Zhang Z, Ge L, Ratcliffe MB, Zohdi TI, Hsu E, Navia JL, Kassab GS, Guccione JM. Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function. J Appl Physiol (1985). 2013 Jul 1; 115(1):136-44. PMID: 23640586; PMCID: PMC3727014.
      21. Wenk JF, Ge L, Zhang Z, Mojsejenko D, Potter DD, Tseng EE, Guccione JM, Ratcliffe MB. Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart. Ann Thorac Surg. 2013 Jun; 95(6):2022-7. PMID: 23643546; PMCID: PMC3702266.
      22. Borazjani I, Ge L, Le T, Sotiropoulos F. A parallel overset-curvilinear-immersed boundary framework for simulating complex 3D incompressible flows. Comput Fluids. 2013 Apr 1; 77:76-96. PMID: 23833331.
        View in: PubMed
      23. Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction. Ann Thorac Surg. 2013 May; 95(5):1619-25. PMID: 23523189; PMCID: PMC3640420.
      24. Lee LC, Wall ST, Klepach D, Ge L, Zhang Z, Lee RJ, Hinson A, Gorman JH, Gorman RC, Guccione JM. Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart. Int J Cardiol. 2013 Oct 3; 168(3):2022-8. PMID: 23394895; PMCID: PMC3748222.
      25. Ratcliffe M, Cambronero N, Ge L. Invited commentary. Ann Thorac Surg. 2013 Jan; 95(1):162. PMID: 23272834.
        View in: PubMed
      26. Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE. Material properties of CorCap passive cardiac support device. Ann Thorac Surg. 2013 Jan; 95(1):148-54. PMID: 22981255; PMCID: PMC3527692.
      27. Chitsaz S, Azadani AN, Matthews PB, Chuter TA, Tseng EE, Ge L. Hemodynamic determinants of aortic dissection propagation by 2D computational modeling: implications for endovascular stent-grafting. J Cardiovasc Surg (Torino). 2012 Oct; 53(5):631-40. PMID: 22820737.
        View in: PubMed
      28. Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Ge L, Tseng EE. Regional mechanical properties of human pulmonary root used for the Ross operation. J Heart Valve Dis. 2012 Jul; 21(4):527-34. PMID: 22953683.
        View in: PubMed
      29. Carrick R, Ge L, Lee LC, Zhang Z, Mishra R, Axel L, Guccione JM, Grossi EA, Ratcliffe MB. Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stress. Ann Thorac Surg. 2012 Jun; 93(6):1964-71. PMID: 22560323; PMCID: PMC3470864.
      30. Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. The benefit of enhanced contractility in the infarct borderzone: a virtual experiment. Front Physiol. 2012; 3:86. PMID: 22509168; PMCID: PMC3321638.
      31. Wenk JF, Klepach D, Lee LC, Zhang Z, Ge L, Tseng EE, Martin A, Kozerke S, Gorman JH, Gorman RC, Guccione JM. First evidence of depressed contractility in the border zone of a human myocardial infarction. Ann Thorac Surg. 2012 Apr; 93(4):1188-93. PMID: 22326127; PMCID: PMC3314154.
      32. Wenk JF, Ge L, Zhang Z, Soleimani M, Potter DD, Wallace AW, Tseng E, Ratcliffe MB, Guccione JM. A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure. Comput Methods Biomech Biomed Engin. 2013; 16(8):807-18. PMID: 22248290; PMCID: PMC3367128.
      33. Wong VM, Wenk JF, Zhang Z, Cheng G, Acevedo-Bolton G, Burger M, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB, Ge L. The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation. Ann Thorac Surg. 2012 Mar; 93(3):776-82. PMID: 22245588; PMCID: PMC3432639.
      34. Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Wisneski A, Ge L, Tseng EE. Biomechanical comparison of human pulmonary and aortic roots. Eur J Cardiothorac Surg. 2012 May; 41(5):1111-6. PMID: 22219450.
        View in: PubMed
      35. Azadani AN, Chitsaz S, Matthews PB, Jaussaud N, Leung J, Tsinman T, Ge L, Tseng EE. Comparison of mechanical properties of human ascending aorta and aortic sinuses. Ann Thorac Surg. 2012 Jan; 93(1):87-94. PMID: 22075218.
        View in: PubMed
      36. Soleimani M, Khazalpour M, Cheng G, Zhang Z, Acevedo-Bolton G, Saloner DA, Mishra R, Wallace AW, Guccione JM, Ge L, Ratcliffe MB. Moderate mitral regurgitation accelerates left ventricular remodeling after posterolateral myocardial infarction. Ann Thorac Surg. 2011 Nov; 92(5):1614-20. PMID: 21945222; PMCID: PMC3253877.
      37. Lee LC, Wenk JF, Klepach D, Zhang Z, Saloner D, Wallace AW, Ge L, Ratcliffe MB, Guccione JM. A novel method for quantifying in-vivo regional left ventricular myocardial contractility in the border zone of a myocardial infarction. J Biomech Eng. 2011 Sep; 133(9):094506. PMID: 22010752; PMCID: PMC3207355.
      38. Azadani AN, Jaussaud N, Ge L, Chitsaz S, Chuter TA, Tseng EE. Valve-in-valve hemodynamics of 20-mm transcatheter aortic valves in small bioprostheses. Ann Thorac Surg. 2011 Aug; 92(2):548-55. PMID: 21704287.
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      39. Zhao X, Wenk JF, Burger M, Liu Y, Das MK, Combs W, Ge L, Guccione JM, Kassab GS. Simulation of mechanical environment in active lead fixation: effect of fixation helix size. J Biomech Eng. 2011 Jun; 133(6):061006. PMID: 21744926.
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      40. Wenk JF, Sun K, Zhang Z, Soleimani M, Ge L, Saloner D, Wallace AW, Ratcliffe MB, Guccione JM. Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction. J Biomech Eng. 2011 Apr; 133(4):044501. PMID: 21428685; PMCID: PMC3097530.
      41. Matthews PB, Jhun CS, Yaung S, Azadani AN, Guccione JM, Ge L, Tseng EE. Finite element modeling of the pulmonary autograft at systemic pressure before remodeling. J Heart Valve Dis. 2011 Jan; 20(1):45-52. PMID: 21404897.
        View in: PubMed
      42. Zhang Z, Tendulkar A, Sun K, Saloner DA, Wallace AW, Ge L, Guccione JM, Ratcliffe MB. Comparison of the Young-Laplace law and finite element based calculation of ventricular wall stress: implications for postinfarct and surgical ventricular remodeling. Ann Thorac Surg. 2011 Jan; 91(1):150-6. PMID: 21172505; PMCID: PMC3058250.
      43. Simon HA, Ge L, Sotiropoulos F, Yoganathan AP. Numerical investigation of the performance of three hinge designs of bileaflet mechanical heart valves. Ann Biomed Eng. 2010 Nov; 38(11):3295-310. PMID: 20571852; PMCID: PMC2949571.
      44. Matthews PB, Azadani AN, Jhun CS, Ge L, Guy TS, Guccione JM, Tseng EE. Comparison of porcine pulmonary and aortic root material properties. Ann Thorac Surg. 2010 Jun; 89(6):1981-8. PMID: 20494060.
        View in: PubMed
      45. Rayz VL, Boussel L, Ge L, Leach JR, Martin AJ, Lawton MT, McCulloch C, Saloner D. Flow residence time and regions of intraluminal thrombus deposition in intracranial aneurysms. Ann Biomed Eng. 2010 Oct; 38(10):3058-69. PMID: 20499185; PMCID: PMC2940011.
      46. Azadani AN, Jaussaud N, Matthews PB, Ge L, Chuter TA, Tseng EE. Transcatheter aortic valves inadequately relieve stenosis in small degenerated bioprostheses. Interact Cardiovasc Thorac Surg. 2010 Jul; 11(1):70-7. PMID: 20395249.
        View in: PubMed
      47. Ge L, Sotiropoulos F. Direction and magnitude of blood flow shear stresses on the leaflets of aortic valves: is there a link with valve calcification? J Biomech Eng. 2010 Jan; 132(1):014505. PMID: 20524753.
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      48. Simon HA, Ge L, Borazjani I, Sotiropoulos F, Yoganathan AP. Simulation of the three-dimensional hinge flow fields of a bileaflet mechanical heart valve under aortic conditions. Ann Biomed Eng. 2010 Mar; 38(3):841-53. PMID: 19960368; PMCID: PMC2841271.
      49. Azadani AN, Jaussaud N, Matthews PB, Ge L, Guy TS, Chuter TA, Tseng EE. Valve-in-valve implantation using a novel supravalvular transcatheter aortic valve: proof of concept. Ann Thorac Surg. 2009 Dec; 88(6):1864-9. PMID: 19932250.
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      50. Azadani AN, Jaussaud N, Matthews PB, Ge L, Guy TS, Chuter TA, Tseng EE. Energy loss due to paravalvular leak with transcatheter aortic valve implantation. Ann Thorac Surg. 2009 Dec; 88(6):1857-63. PMID: 19932249.
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      51. Matthews PB, Kim B, Azadani AN, Guy TS, Guccione JM, Ge L, Tseng EE. Biomechanical perspective on the porcine pulmonary root prior to Ross remodeling. J Heart Valve Dis. 2009 Nov; 18(6):682-90. PMID: 20099718.
        View in: PubMed
      52. Borazjani I, Ge L, Sotiropoulos F. High-resolution fluid-structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta. Ann Biomed Eng. 2010 Feb; 38(2):326-44. PMID: 19806458; PMCID: PMC3154744.
      53. Dwyer HA, Matthews PB, Azadani A, Ge L, Guy TS, Tseng EE. Migration forces of transcatheter aortic valves in patients with noncalcific aortic insufficiency. J Thorac Cardiovasc Surg. 2009 Nov; 138(5):1227-33. PMID: 19748632.
        View in: PubMed
      54. Azadani AN, Jaussaud N, Matthews PB, Chuter TA, Ge L, Guy TS, Guccione J, Tseng EE. Aortic valve-in-valve implantation: impact of transcatheter- bioprosthesis size mismatch. J Heart Valve Dis. 2009 Jul; 18(4):367-73. PMID: 19852139.
        View in: PubMed
      55. Dwyer HA, Matthews PB, Azadani A, Jaussaud N, Ge L, Guy TS, Tseng EE. Computational fluid dynamics simulation of transcatheter aortic valve degeneration. Interact Cardiovasc Thorac Surg. 2009 Aug; 9(2):301-8. PMID: 19414489.
        View in: PubMed
      56. Azadani AN, Matthews PB, Ge L, Shen Y, Jhun CS, Guy TS, Tseng EE. Mechanical properties of surgical glues used in aortic root replacement. Ann Thorac Surg. 2009 Apr; 87(4):1154-60. PMID: 19324142.
        View in: PubMed
      57. Ge L, Ratcliffe M. The use of computational flow modeling (CFD) to determine the effect of left ventricular shape on blood flow in the left ventricle. Ann Thorac Surg. 2009 Apr; 87(4):993-4. PMID: 19324118.
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      58. Rayz VL, Boussel L, Lawton MT, Acevedo-Bolton G, Ge L, Young WL, Higashida RT, Saloner D. Numerical modeling of the flow in intracranial aneurysms: prediction of regions prone to thrombus formation. Ann Biomed Eng. 2008 Nov; 36(11):1793-804. PMID: 18787954; PMCID: PMC2664710.
      59. Borazjani I, Ge L, Sotiropoulos F. Curvilinear Immersed Boundary Method for Simulating Fluid Structure Interaction with Complex 3D Rigid Bodies. J Comput Phys. 2008 Aug 10; 227(16):7587-7620. PMID: 20981246.
        View in: PubMed
      60. Ge L, Dasi LP, Sotiropoulos F, Yoganathan AP. Characterization of hemodynamic forces induced by mechanical heart valves: Reynolds vs. viscous stresses. Ann Biomed Eng. 2008 Feb; 36(2):276-97. PMID: 18049902.
        View in: PubMed
      61. Ge L, Sotiropoulos F. A Numerical Method for Solving the 3D Unsteady Incompressible Navier-Stokes Equations in Curvilinear Domains with Complex Immersed Boundaries. J Comput Phys. 2007 Aug; 225(2):1782-1809. PMID: 19194533.
        View in: PubMed
      62. Ge L, Leo HL, Sotiropoulos F, Yoganathan AP. Flow in a mechanical bileaflet heart valve at laminar and near-peak systole flow rates: CFD simulations and experiments. J Biomech Eng. 2005 Oct; 127(5):782-97. PMID: 16248308.
        View in: PubMed
      63. Pekkan K, de Zélicourt D, Ge L, Sotiropoulos F, Frakes D, Fogel MA, Yoganathan AP. Physics-driven CFD modeling of complex anatomical cardiovascular flows-a TCPC case study. Ann Biomed Eng. 2005 Mar; 33(3):284-300. PMID: 15868719.
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      64. Ge L, Jones SC, Sotiropoulos F, Healy TM, Yoganathan AP. Numerical simulation of flow in mechanical heart valves: grid resolution and the assumption of flow symmetry. J Biomech Eng. 2003 Oct; 125(5):709-18. PMID: 14618930.
        View in: PubMed
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