Lucas Schirmer, MD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentRegeneration Medicine
Address401 Parnassus Ave, LangPorter
San Francisco CA 94143
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    University of GöttingenM.D.2008School of Medicine
    Technical University of MunichBoard Certification2014Neurology
    Technical University of MunichVenia Legendi2015Neurology
    Collapse Awards and Honors
    German Research Foundation2015 - 2017Postdoctoral Fellowship
    Genzyme Corporation2013 - 2015Neuroimmunology Fellowship
    German Multiple Sclerosis Society2013Hans Georg Queckenstedt Award
    American Academy of Neurology2013International Scholarship Award
    Technical University of Munich2011Intramural Research Grant (KKF)
    Multiple Sclerosis International Federation2010Du Pré Grant
    German Society of Neurology2009Felgenhauer Fellowship
    University of Göttingen2009School of Medicine Thesis Award ("summa cum laude")
    German Research Foundation2003 - 2006Fellowship, Graduate School 632 “Neuroplasticity: From Molecules to Systems“

    Collapse Overview 
    Collapse overview
    As a neurologist physician-scientist I focus my research on glia biology working with experimental models and human pathology in a synergistic way. I would like to understand the underlying pathophysiological mechanisms that lead to neurodegeneration, scar formation and unsatisfactory remyelination and work on strategies to foster repair in progressive multiple sclerosis (MS). My clinical interests are focused on several aspects of neuroinflammation and neurooncology with a particular emphasis on MS, glioma, neuroinfectious diseases and spinal cord injury.

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017 Jan 18. PMID: 28099414.
      View in: PubMed
    2. Schirmer L, Worthington V, Solloch U, Loleit V, Grummel V, Lakdawala N, Grant D, Wassmuth R, Schmidt AH, Gebhardt F, Andlauer TF, Sauter J, Berthele A, Lunn MP, Hemmer B, et al. Higher frequencies of HLA DQB1*05:01 and anti-glycosphingolipid antibodies in a cluster of severe Guillain-Barré syndrome. J Neurol. 2016 Aug 2. PMID: 27485170.
      View in: PubMed
    3. Boeckh-Behrens T, Kleine JF, Zimmer C, Neff F, Scheipl F, Pelisek J, Schirmer L, Nguyen K, Karatas D, Poppert H. Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke. Stroke. 2016 Jul; 47(7):1864-71. PMID: 27197854.
      View in: PubMed
    4. Schirmer L, Wölfel S, Georgi E, Ploner M, Bauer B, Hemmer B. Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis. Open Forum Infect Dis. 2015 Sep; 2(3):ofv124. PMID: 26393235; PMCID: PMC4569839.
    5. Boeckh-Behrens T, Schubert M, Förschler A, Prothmann S, Kreiser K, Zimmer C, Riegger J, Bauer J, Neff F, Kehl V, Pelisek J, Schirmer L, Mehr M, Poppert H. The Impact of Histological Clot Composition in Embolic Stroke. Clin Neuroradiol. 2016 Jun; 26(2):189-97. PMID: 25261075.
      View in: PubMed
    6. Schirmer L, Srivastava R, Kalluri SR, Böttinger S, Herwerth M, Carassiti D, Srivastava B, Gempt J, Schlegel J, Kuhlmann T, Korn T, Reynolds R, Hemmer B. Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014 Jun; 75(6):810-28. PMID: 24777949.
      View in: PubMed
    7. Schirmer L, Srivastava R, Hemmer B. To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis. Mult Scler. 2014 Mar; 20(3):271-9. PMID: 24589684.
      View in: PubMed
    8. Schirmer L, Rothhammer V, Hemmer B, Korn T. Enriched CD161high CCR6+ ?d T cells in the cerebrospinal fluid of patients with multiple sclerosis. JAMA Neurol. 2013 Mar 1; 70(3):345-51. PMID: 23599932.
      View in: PubMed
    9. Srivastava R, Aslam M, Kalluri SR, Schirmer L, Buck D, Tackenberg B, Rothhammer V, Chan A, Gold R, Berthele A, Bennett JL, Korn T, Hemmer B. Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med. 2012 Jul 12; 367(2):115-23. PMID: 22784115.
      View in: PubMed
    10. Schirmer L, Merkler D, König FB, Brück W, Stadelmann C. Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions. Brain Pathol. 2013 Jan; 23(1):2-12. PMID: 22612622.
      View in: PubMed
    11. Lahmer T, Küchle C, Schirmer L, Heemann U, Lutz J, Thürmel K. Kidney transplant after preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome. Exp Clin Transplant. 2012 Jun; 10(3):299-301. PMID: 22631071.
      View in: PubMed
    12. Sellner J, Schirmer L, Erik Gilhus N, Grisold W, Struhal W. The Open Facilities for Training in European Neurology (OFTEN): an emerging pan-European exchange programme for junior neurologists. Eur J Neurol. 2012 Jun; 19(6):e54-5. PMID: 22448868.
      View in: PubMed
    13. Schirmer L, Seifert CL, Pfeifenbring S, Wunderlich S, Stadelmann C, Hemmer B. Clinicopathological considerations in acute disseminated encephalomyelitis (ADEM): a fulminant case with favorable outcome. J Neurol. 2012 Apr; 259(4):753-5. PMID: 21901482.
      View in: PubMed
    14. Schirmer L, Antel JP, Brück W, Stadelmann C. Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol. 2011 Jul; 21(4):428-40. PMID: 21114565.
      View in: PubMed
    15. Sellner J, Schirmer L, Hemmer B, Mühlau M. [Radiologically isolated syndrome: multiple sclerosis based solely on MRI findings?]. Nervenarzt. 2010 Oct; 81(10):1208-17. PMID: 20422146.
      View in: PubMed
    16. Sellner J, Schirmer L, Hemmer B, Mühlau M. The radiologically isolated syndrome: take action when the unexpected is uncovered? J Neurol. 2010 Oct; 257(10):1602-11. PMID: 20503053.
      View in: PubMed
    17. Schirmer L, Albert M, Buss A, Schulz-Schaeffer WJ, Antel JP, Brück W, Stadelmann C. Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol. 2009 Nov; 66(5):698-704. PMID: 19938172.
      View in: PubMed
    Lucas's Networks
    Derived automatically from this person's publications.
    People in Profiles who have published with this person.
    Related Authors
    People who share related concepts with this person.
    Back to TOP