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    Lucas Schirmer, MD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentRegeneration Medicine
    Address401 Parnassus Ave, LangPorter
    San Francisco CA 94143
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      Collapse Biography 
      Collapse Education and Training
      University of GöttingenM.D.School of Medicine2008
      Technical University of MunichBoard CertificationNeurology2014
      Technical University of MunichVenia LegendiNeurology2015
      Collapse Awards and Honors
      German Research Foundation2015 - 2017Postdoctoral Fellowship
      Genzyme Corporation2013 - 2015Neuroimmunology Fellowship
      German Multiple Sclerosis Society2013Hans Georg Queckenstedt Award
      American Academy of Neurology2013International Scholarship Award
      Technical University of Munich2011Intramural Research Grant (KKF)
      Multiple Sclerosis International Federation2010Du Pré Grant
      German Society of Neurology2009Felgenhauer Fellowship
      University of Göttingen2009School of Medicine Thesis Award ("summa cum laude")
      German Research Foundation2003 - 2006Graduate School 632 “Neuroplasticity: From Molecules to Systems“

      Collapse Overview 
      Collapse Interests
      As a neurologist physician-scientist I focus my research on glia biology working with experimental models and human pathology in a synergistic way. I would like to understand the underlying pathophysiological mechanisms that lead to neurodegeneration, scar formation and unsatisfactory remyelination and work on strategies to foster repair in progressive multiple sclerosis (MS). My clinical interests are focused on several aspects of neuroinflammation and neurooncology with a particular emphasis on MS, glioma, neuroinfectious diseases and spinal cord injury.

      Collapse ORNG Applications 
      Collapse Featured Publications

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Schirmer L, Worthington V, Solloch U, Loleit V, Grummel V, Lakdawala N, Grant D, Wassmuth R, Schmidt AH, Gebhardt F, Andlauer TF, Sauter J, Berthele A, Lunn MP, Hemmer B, et al. Higher frequencies of HLA DQB1*05:01 and anti-glycosphingolipid antibodies in a cluster of severe Guillain-Barré syndrome. J Neurol. 2016 Aug 2. PMID: 27485170.
        View in: PubMed
      2. Boeckh-Behrens T, Kleine JF, Zimmer C, Neff F, Scheipl F, Pelisek J, Schirmer L, Nguyen K, Karatas D, Poppert H. Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke. Stroke. 2016 Jul; 47(7):1864-71. PMID: 27197854.
        View in: PubMed
      3. Schirmer L, Wölfel S, Georgi E, Ploner M, Bauer B, Hemmer B. Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis. Open Forum Infect Dis. 2015 Sep; 2(3):ofv124. PMID: 26393235; PMCID: PMC4569839.
      4. Boeckh-Behrens T, Schubert M, Förschler A, Prothmann S, Kreiser K, Zimmer C, Riegger J, Bauer J, Neff F, Kehl V, Pelisek J, Schirmer L, Mehr M, Poppert H. The Impact of Histological Clot Composition in Embolic Stroke. Clin Neuroradiol. 2016 Jun; 26(2):189-97. PMID: 25261075.
        View in: PubMed
      5. Schirmer L, Srivastava R, Kalluri SR, Böttinger S, Herwerth M, Carassiti D, Srivastava B, Gempt J, Schlegel J, Kuhlmann T, Korn T, Reynolds R, Hemmer B. Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014 Jun; 75(6):810-28. PMID: 24777949.
        View in: PubMed
      6. Schirmer L, Srivastava R, Hemmer B. To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis. Mult Scler. 2014 Mar; 20(3):271-9. PMID: 24589684.
        View in: PubMed
      7. Schirmer L, Rothhammer V, Hemmer B, Korn T. Enriched CD161high CCR6+ ?d T cells in the cerebrospinal fluid of patients with multiple sclerosis. JAMA Neurol. 2013 Mar 1; 70(3):345-51. PMID: 23599932.
        View in: PubMed
      8. Srivastava R, Aslam M, Kalluri SR, Schirmer L, Buck D, Tackenberg B, Rothhammer V, Chan A, Gold R, Berthele A, Bennett JL, Korn T, Hemmer B. Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med. 2012 Jul 12; 367(2):115-23. PMID: 22784115.
        View in: PubMed
      9. Schirmer L, Merkler D, König FB, Brück W, Stadelmann C. Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions. Brain Pathol. 2013 Jan; 23(1):2-12. PMID: 22612622.
        View in: PubMed
      10. Lahmer T, Küchle C, Schirmer L, Heemann U, Lutz J, Thürmel K. Kidney transplant after preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome. Exp Clin Transplant. 2012 Jun; 10(3):299-301. PMID: 22631071.
        View in: PubMed
      11. Sellner J, Schirmer L, Erik Gilhus N, Grisold W, Struhal W. The Open Facilities for Training in European Neurology (OFTEN): an emerging pan-European exchange programme for junior neurologists. Eur J Neurol. 2012 Jun; 19(6):e54-5. PMID: 22448868.
        View in: PubMed
      12. Schirmer L, Seifert CL, Pfeifenbring S, Wunderlich S, Stadelmann C, Hemmer B. Clinicopathological considerations in acute disseminated encephalomyelitis (ADEM): a fulminant case with favorable outcome. J Neurol. 2012 Apr; 259(4):753-5. PMID: 21901482.
        View in: PubMed
      13. Schirmer L, Antel JP, Brück W, Stadelmann C. Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol. 2011 Jul; 21(4):428-40. PMID: 21114565.
        View in: PubMed
      14. Sellner J, Schirmer L, Hemmer B, Mühlau M. [Radiologically isolated syndrome: multiple sclerosis based solely on MRI findings?]. Nervenarzt. 2010 Oct; 81(10):1208-17. PMID: 20422146.
        View in: PubMed
      15. Sellner J, Schirmer L, Hemmer B, Mühlau M. The radiologically isolated syndrome: take action when the unexpected is uncovered? J Neurol. 2010 Oct; 257(10):1602-11. PMID: 20503053.
        View in: PubMed
      16. Schirmer L, Albert M, Buss A, Schulz-Schaeffer WJ, Antel JP, Brück W, Stadelmann C. Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol. 2009 Nov; 66(5):698-704. PMID: 19938172.
        View in: PubMed
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