Marcel Alavi Alavi Khorassani Moghadam, PhD
|School||UCSF School of Medicine|
|Address||10 Koret Way|
San Francisco CA 94143
|Foundation Fighting Blindness||2014||Travel Award - RD2014|
|Eberhard Karls Universität, Tübingen, Germany||2010||PhD with the highest honors, summa cum laude|
|GlaxoSmithKline||2009||Travel Award - ARVO 2009|
|European Retinal Research Training Network RETNET||2007||Fellowship|
|GlaxoSmithKline||2007||Travel Award - ARVO 2007|
I study different aspects related to ER stress, a condition where misfolded proteins accumulate within cells ultimately causing cell death. I established tools for in vivo monitoring of ER stress in collaboration with Jonathan Lin at UCSD. We showed increased ER stress in vivo in a mouse model for retinal degeneration. I also characterized the retinal phenotype of mutant type IV collagen mice and found vascular lesions associated with ER stress. In collaboration with Scott Oakes and Feroz Papa at UCSF I tested new therapies preventing cells to die upon ER stress.
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