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    Mark Le Gros, PhD

    SchoolUCSF School of Medicine
    Address1550 4th Street, Bldg 19B
    San Francisco CA 94158
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Tjong H, Li W, Kalhor R, Dai C, Hao S, Gong K, Zhou Y, Li H, Zhou XJ, Le Gros MA, Larabell CA, Chen L, Alber F. Population-based 3D genome structure analysis reveals driving forces in spatial genome organization. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):E1663-72. PMID: 26951677.
        View in: PubMed
      2. Do M, Isaacson SA, McDermott G, Le Gros MA, Larabell CA. Imaging and characterizing cells using tomography. Arch Biochem Biophys. 2015 Sep 1; 581:111-21. PMID: 25602704; PMCID: PMC4506273 [Available on 09/01/16].
      3. Smith EA, McDermott G, Do M, Leung K, Panning B, Le Gros MA, Larabell CA. Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies. Biophys J. 2014 Oct 21; 107(8):1988-96. PMID: 25418180; PMCID: PMC4213715.
      4. Le Gros MA, McDermott G, Cinquin BP, Smith EA, Do M, Chao WL, Naulleau PP, Larabell CA. Biological soft X-ray tomography on beamline 2.1 at the Advanced Light Source. J Synchrotron Radiat. 2014 Nov; 21(Pt 6):1370-7. PMID: 25343808; PMCID: PMC4211134.
      5. Cinquin BP, Do M, McDermott G, Walters AD, Myllys M, Smith EA, Cohen-Fix O, Le Gros MA, Larabell CA. Putting molecules in their place. J Cell Biochem. 2014 Feb; 115(2):209-16. PMID: 23966233; PMCID: PMC3865101.
      6. Smith EA, Cinquin BP, Do M, McDermott G, Le Gros MA, Larabell CA. Correlative cryogenic tomography of cells using light and soft x-rays. Ultramicroscopy. 2014 Aug; 143:33-40. PMID: 24355261; PMCID: PMC4013260.
      7. Isaacson SA, Larabell CA, Le Gros MA, McQueen DM, Peskin CS. The influence of spatial variation in chromatin density determined by X-ray tomograms on the time to find DNA binding sites. Bull Math Biol. 2013 Nov; 75(11):2093-117. PMID: 23955281; PMCID: PMC3934756.
      8. Smith EA, Cinquin BP, McDermott G, Le Gros MA, Parkinson DY, Kim HT, Larabell CA. Correlative microscopy methods that maximize specimen fidelity and data completeness, and improve molecular localization capabilities. J Struct Biol. 2013 Oct; 184(1):12-20. PMID: 23531637; PMCID: PMC3758393.
      9. Parkinson DY, Epperly LR, McDermott G, Le Gros MA, Boudreau RM, Larabell CA. Nanoimaging cells using soft X-ray tomography. Methods Mol Biol. 2013; 950:457-81. PMID: 23086890.
        View in: PubMed
      10. Murphy SV, Lim R, Heraud P, Cholewa M, Le Gros M, de Jonge MD, Howard DL, Paterson D, McDonald C, Atala A, Jenkin G, Wallace EM. Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator. PLoS One. 2012; 7(9):e46533. PMID: 23029546; PMCID: PMC3460882.
      11. McDermott G, Fox DM, Epperly L, Wetzler M, Barron AE, Le Gros MA, Larabell CA. Visualizing and quantifying cell phenotype using soft X-ray tomography. Bioessays. 2012 Apr; 34(4):320-7. PMID: 22290620; PMCID: PMC3343367.
      12. McDermott G, Le Gros MA, Larabell CA. Visualizing cell architecture and molecular location using soft x-ray tomography and correlated cryo-light microscopy. Annu Rev Phys Chem. 2012; 63:225-39. PMID: 22242730; PMCID: PMC3349341.
      13. Parkinson DY, Knoechel C, Yang C, Larabell CA, Le Gros MA. Automatic alignment and reconstruction of images for soft X-ray tomography. J Struct Biol. 2012 Feb; 177(2):259-66. PMID: 22155289; PMCID: PMC3288662.
      14. Hanssen E, Knoechel C, Dearnley M, Dixon MW, Le Gros M, Larabell C, Tilley L. Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum. J Struct Biol. 2012 Feb; 177(2):224-32. PMID: 21945653; PMCID: PMC3349340.
      15. Uchida M, Sun Y, McDermott G, Knoechel C, Le Gros MA, Parkinson D, Drubin DG, Larabell CA. Quantitative analysis of yeast internal architecture using soft X-ray tomography. Yeast. 2011 Mar; 28(3):227-36. PMID: 21360734; PMCID: PMC3404734.
      16. Uchida M, McDermott G, Wetzler M, Le Gros MA, Myllys M, Knoechel C, Barron AE, Larabell CA. Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicans. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19375-80. PMID: 19880740; PMCID: PMC2780763.
      17. McDermott G, Le Gros MA, Knoechel CG, Uchida M, Larabell CA. Soft X-ray tomography and cryogenic light microscopy: the cool combination in cellular imaging. Trends Cell Biol. 2009 Nov; 19(11):587-95. PMID: 19818625; PMCID: PMC3276488.
      18. Le Gros MA, McDermott G, Uchida M, Knoechel CG, Larabell CA. High-aperture cryogenic light microscopy. J Microsc. 2009 Jul; 235(1):1-8. PMID: 19566622; PMCID: PMC3350647.
      19. Ashcroft JM, Gu W, Zhang T, Hughes SM, Hartman KB, Hofmann C, Kanaras AG, Kilcoyne DA, Le Gros M, Yin Y, Alivisatos AP, Larabell CA. TiO2 nanoparticles as a soft X-ray molecular probe. Chem Commun (Camb). 2008 Jun 7; (21):2471-3. PMID: 18491018; PMCID: PMC3355471.
      20. Parkinson DY, McDermott G, Etkin LD, Le Gros MA, Larabell CA. Quantitative 3-D imaging of eukaryotic cells using soft X-ray tomography. J Struct Biol. 2008 Jun; 162(3):380-6. PMID: 18387313; PMCID: PMC2505111.
      21. Gu W, Etkin LD, Le Gros MA, Larabell CA. X-ray tomography of Schizosaccharomyces pombe. Differentiation. 2007 Jul; 75(6):529-35. PMID: 17459084.
        View in: PubMed
      22. Fu A, Gu W, Boussert B, Koski K, Gerion D, Manna L, Le Gros M, Larabell CA, Alivisatos AP. Semiconductor quantum rods as single molecule fluorescent biological labels. Nano Lett. 2007 Jan; 7(1):179-82. PMID: 17212460; PMCID: PMC3984543.
      23. Gu W, Pellegrino T, Parak WJ, Boudreau R, Le Gros MA, Alivisatos AP, Larabell CA. Measuring cell motility using quantum dot probes. Methods Mol Biol. 2007; 374:125-31. PMID: 17237535.
        View in: PubMed
      24. Le Gros MA, McDermott G, Larabell CA. X-ray tomography of whole cells. Curr Opin Struct Biol. 2005 Oct; 15(5):593-600. PMID: 16153818.
        View in: PubMed
      25. Gu W, Pellegrino T, Parak WJ, Boudreau R, Le Gros MA, Gerion D, Alivisatos AP, Larabell CA. Quantum-dot-based cell motility assay. Sci STKE. 2005 Jun 28; 2005(290):pl5. PMID: 15985641.
        View in: PubMed
      26. Larabell CA, Le Gros MA. X-ray tomography generates 3-D reconstructions of the yeast, saccharomyces cerevisiae, at 60-nm resolution. Mol Biol Cell. 2004 Mar; 15(3):957-62. PMID: 14699066; PMCID: PMC363052.
      27. Pellegrino T, Parak WJ, Boudreau R, Le Gros MA, Gerion D, Alivisatos AP, Larabell CA. Quantum dot-based cell motility assay. Differentiation. 2003 Dec; 71(9-10):542-8. PMID: 14686951.
        View in: PubMed
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