Marton Siklos, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address600 16th Street
San Francisco CA 94158
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    1. Pierce EN, Piyankarage SC, Dunlap T, Litosh V, Siklos MI, Wang YT, Thatcher GR. Prodrugs Bioactivated to Quinones Target NF-?B and Multiple Protein Networks: Identification of the Quinonome. Chem Res Toxicol. 2016 Jul 18; 29(7):1151-9. PMID: 27258437.
      View in: PubMed
    2. Kastrati I, Siklos MI, Calderon-Gierszal EL, El-Shennawy L, Georgieva G, Thayer EN, Thatcher GR, Frasor J. Dimethyl Fumarate Inhibits the Nuclear Factor ?B Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. J Biol Chem. 2016 Feb 12; 291(7):3639-47. PMID: 26683377.
      View in: PubMed
    3. Fà M, Zhang H, Staniszewski A, Saeed F, Shen LW, Schiefer IT, Siklos MI, Tapadar S, Litosh VA, Libien J, Petukhov PA, Teich AF, Thatcher GR, Arancio O. Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. J Alzheimers Dis. 2015 Oct 17; 49(3):707-21. PMID: 26484927.
      View in: PubMed
    4. Siklos M, BenAissa M, Thatcher GR. Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors. Acta Pharm Sin B. 2015 Nov; 5(6):506-19. PMID: 26713267.
      View in: PubMed
    5. Hemachandra LP, Patel H, Chandrasena RE, Choi J, Piyankarage SC, Wang S, Wang Y, Thayer EN, Scism RA, Michalsen BT, Xiong R, Siklos MI, Bolton JL, Thatcher GR. SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites. Cancer Prev Res (Phila). 2014 May; 7(5):505-15. PMID: 24598415; PMCID: PMC4128015.
    6. Patel HK, Siklos MI, Abdelkarim H, Mendonca EL, Vaidya A, Petukhov PA, Thatcher GR. A chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy. ChemMedChem. 2014 Mar; 9(3):602-13. PMID: 23956109; PMCID: PMC3962780.
    7. Schiefer IT, Tapadar S, Litosh V, Siklos M, Scism R, Wijewickrama GT, Chandrasena EP, Sinha V, Tavassoli E, Brunsteiner M, Fa' M, Arancio O, Petukhov P, Thatcher GR. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013 Aug 8; 56(15):6054-68. PMID: 23834438; PMCID: PMC3962784.
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