Loading...

Mary Helen Barcellos-Hoff, PhD

Address2340 Sutter Street
San Francisco CA 94115
Phone415-476-8091
EmailMary.Barcellos-Hoff@ucsf.edu
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of ChicagoA.B.1978Biopsychology
    University of California, San FranciscoPh.D.1986Experimental Pathology
    University of California, BerkeleyPostdoctoral training1988Biophysics

    Collapse Overview 
    Collapse Overview
    The Barcellos-Hoff laboratory studies radiation carcinogenesis and biologically augmented radiotherapy. Dr. Barcellos-Hoff received an undergraduate degree from the University of Chicago and earned a doctoral degree in experimental pathology from the University of California, San Francisco. She conducted postdoctoral research on extracellular matrix mediated functional differentiation with Mina Bissell at the Lawrence Berkeley National Laboratory (LBNL). She joined LBNL as a staff scientist, where she rose from postdoctoral fellow to Senior Scientist and Associate Director of the Life Sciences Division. She joined New York University School of Medicine in 2008 as Director of Radiation Biology in the Department of Radiation Oncology. She moved to UCSF as Professor and Vice Chair of Research in the Department of Radiation Oncology in 2015.

    Dr. Barcellos-Hoff promotes the application of systems biology approaches to problems in radiation research. She was Chief Scientist for the Low Dose Radiation Research program in the Department of Energy (DOE) from 2006-2010. Her studies funded by DOE and NASA describe the complexity of radiation effects on biological systems and have generated new perspectives on mechanisms underlying radiation carcinogenesis.

    Translational research based on aspects of these low dose studies provides a rationale for implementing TGFß inhibition during radiotherapy. TGF? is activated by radiation and mediates the DNA damage response as well as the composition of the tumor microenvironment, particularly tumor immunological responses. Detailed understanding of its contributions to tumor response may motivate clinical trials of TGF? inhibitors in radiotherapy.

    Dr. Barcellos-Hoff is a member of AAAS and the American Association of Cancer Research. She is member of the AACR Tumor Microenvironment Working Group, which she chaired from 2012 to 2014, and a founding member of the AACR committee for Radiation Science and Medicine Working Group. She is a long-standing member of the Radiation Research Society and President of the International Association of Radiation Research (2014-2019).


    Collapse Research 
    Collapse Research Activities and Funding
    Contribution of development and age to breast cancer etiology
    NIH R01CA190980Jul 1, 2015 - Dec 31, 2020
    Role: Principal Investigator
    Contextual Glioblastoma Screening For Efficacious Radiation Sensitizers
    NIH R21NS088775Sep 1, 2014 - Aug 31, 2016
    Role: Principal Investigator
    Intercellular Interactions Modulate Carcinogenesis Course: A Dynamic System Study
    NIH U54CA149233May 1, 2010 - Feb 28, 2015
    Role: Co-Investigator
    Biological Basis of Breast Density and Cancer Risk
    NIH/NCI P01CA107584Aug 10, 2006 - Feb 28, 2013
    Role: Co-Investigator
    Model-based predictions of responses RTK Pathway therapies
    NIH U54CA112970Sep 30, 2004 - Feb 28, 2015
    Role: Co-Investigator
    TGFb Regulation of ER Receptor Positive Mammary Cells
    NIH R01AG022413Sep 30, 2003 - Feb 29, 2008
    Role: Principal Investigator
    Gordon Research Conference on Mammary Gland Biology
    NIH R13CA090303May 1, 2001 - Apr 30, 2004
    Role: Principal Investigator
    STROMAL INFLUENCE ON EXPRESSION OF PRENEOPLASIA
    NIH R29CA051841Jan 1, 1991 - Dec 31, 1996
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, Català I, Soler T, Venturas G, Rojo-Sebastian A, Serra H, Cuadras D, Blanco I, Lozano J, Canals F, Sieuwerts AM, de Weerd V, Look MP, Puertas S, García N, Perkins AS, Bonifaci N, Skowron M, Gómez-Baldó L, Hernández V, Martínez-Aranda A, Martínez-Iniesta M, Serrat X, Cerón J, Brunet J, Barretina MP, Gil M, Falo C, Fernández A, Morilla I, Pernas S, Plà MJ, Andreu X, Seguí MA, Ballester R, Castellà E, Nellist M, Morales S, Valls J, Velasco A, Matias-Guiu X, Figueras A, Sánchez-Mut JV, Sánchez-Céspedes M, Cordero A, Gómez-Miragaya J, Palomero L, Gómez A, Gajewski TF, Cohen EE, Jesiotr M, Bodnar L, Quintela-Fandino M, López-Bigas N, Valdés-Mas R, Puente XS, Viñals F, Casanovas O, Graupera M, Hernández-Losa J, Ramón Y Cajal S, García-Alonso L, Saez-Rodriguez J, Esteller M, Sierra A, Martín-Martín N, Matheu A, Carracedo A, González-Suárez E, Nanjundan M, Cortés J, Lázaro C, Odero MD, Martens JW, Moreno-Bueno G, Barcellos-Hoff MH, Villanueva A, Gomis RR, Pujana MA. Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. 2016 Dec 19. PMID: 27991928.
      View in: PubMed
    2. Martinez-Ruiz H, Illa-Bochaca I, Omene C, Hanniford D, Liu Q, Hernando E, Barcellos-Hoff MH. A TGFß-miR-182-BRCA1 axis controls the mammary differentiation hierarchy. Sci Signal. 2016 Dec 06; 9(457):ra118. PMID: 27923913.
      View in: PubMed
    3. Bayin NS, Ma L, Thomas C, Baitalmal R, Sure A, Fansiwala K, Bustoros M, Golfinos JG, Pacione D, Snuderl M, Zagzag D, Barcellos-Hoff MH, Placantonakis D. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-ß Small Molecule Inhibitor. Neoplasia. 2016 Dec; 18(12):795-805. PMID: 27978994.
      View in: PubMed
    4. Formenti SC, Demaria S, Barcellos-Hoff MH, McBride WH. Subverting misconceptions about radiation therapy. Nat Immunol. 2016 Mar 22; 17(4):345. PMID: 27002831.
      View in: PubMed
    5. Barcellos-Hoff MH, Mao JH. HZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary Carcinogenesis. Front Oncol. 2016; 6:57. PMID: 27014632.
      View in: PubMed
    6. Hendry JH, Niwa O, Barcellos-Hoff MH, Globus RK, Harrison JD, Martin MT, Seed TM, Shay JW, Story MD, Suzuki K, Yamashita S. ICRP Publication 131: Stem cell biology with respect to carcinogenesis aspects of radiological protection. Ann ICRP. 2016 Jun; 45(1 Suppl):239-52. PMID: 26956677.
      View in: PubMed
    7. Mittal V, El Rayes T, Narula N, McGraw TE, Altorki NK, Barcellos-Hoff MH. The Microenvironment of Lung Cancer and Therapeutic Implications. Adv Exp Med Biol. 2016; 890:75-110. PMID: 26703800.
      View in: PubMed
    8. Niwa O, Barcellos-Hoff MH, Globus RK, Harrison JD, Hendry JH, Jacob P, Martin MT, Seed TM, Shay JW, Story MD, Suzuki K, Yamashita S. ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection. Ann ICRP. 2015 Dec; 44(3-4):7-357. PMID: 26637346.
      View in: PubMed
    9. Barcellos-Hoff MH, Iliakis G, Jeggo P, McKenna G, O'Neil P, Wallace S. "Praising What Is Lost. . . Radiat Res. 2015 Dec; 184(6):563-4. PMID: 27064149.
      View in: PubMed
    10. Brown M, Held K, Mason K, McBride B, Willey J, Williams J, Barcellos-Hoff MH, Iliakis G, Jeggo P, McKenna G, O'Neil P, Wallace S. Two Perspectives. Radiat Res. 2015 Dec; 184(6):563-4. PMID: 26600171.
      View in: PubMed
    11. Qiang L, Shah P, Barcellos-Hoff M, He YY. TGF-ß signaling links E-cadherin loss to suppression of nucleotide excision repair. Oncogene. 2016 Jun 23; 35(25):3293-302. PMID: 26477308.
      View in: PubMed
    12. Barcellos-Hoff MH, Blakely EA, Burma S, Fornace AJ, Gerson S, Hlatky L, Kirsch DG, Luderer U, Shay J, Wang Y, Weil MM. Concepts and challenges in cancer risk prediction for the space radiation environment. Life Sci Space Res (Amst). 2015 Jul; 6:92-103. PMID: 26256633.
      View in: PubMed
    13. Casey SC, Vaccari M, Al-Mulla F, Al-Temaimi R, Amedei A, Barcellos-Hoff MH, Brown DG, Chapellier M, Christopher J, Curran CS, Forte S, Hamid RA, Heneberg P, Koch DC, Krishnakumar PK, Laconi E, Maguer-Satta V, Marongiu F, Memeo L, Mondello C, Raju J, Roman J, Roy R, Ryan EP, Ryeom S, Salem HK, Scovassi AI, Singh N, Soucek L, Vermeulen L, Whitfield JR, Woodrick J, Colacci A, Bisson WH, Felsher DW. The effect of environmental chemicals on the tumor microenvironment. Carcinogenesis. 2015 Jun; 36 Suppl 1:S160-83. PMID: 26106136; PMCID: PMC4565612 [Available on 06/01/16].
    14. Decarlo L, Mestel C, Barcellos-Hoff MH, Schneider RJ. Eukaryotic Translation Initiation Factor 4E Is a Feed-Forward Translational Coactivator of Transforming Growth Factor ß Early Protransforming Events in Breast Epithelial Cells. Mol Cell Biol. 2015 Aug; 35(15):2597-609. PMID: 25986608; PMCID: PMC4524117 [Available on 02/01/16].
    15. Vanpouille-Box C, Diamond JM, Pilones KA, Zavadil J, Babb JS, Formenti SC, Barcellos-Hoff MH, Demaria S. TGFß Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity. Cancer Res. 2015 Jun 1; 75(11):2232-42. PMID: 25858148; PMCID: PMC4522159 [Available on 06/01/16].
    16. Zhang P, Lo A, Huang Y, Huang G, Liang G, Mott J, Karpen GH, Blakely EA, Bissell MJ, Barcellos-Hoff MH, Snijders AM, Mao JH. Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment. Sci Rep. 2015; 5:8919. PMID: 25747469; PMCID: PMC4352890.
    17. Barcellos-Hoff MH. BUB1-bling over with possibilities. Neoplasia. 2015 Feb; 17(2):153-4. PMID: 25748233; PMCID: PMC4351292.
    18. Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K. Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells. Stem Cell Reports. 2015 Feb 10; 4(2):297-311. PMID: 25619437; PMCID: PMC4325231.
    19. Pellicciotta I, Marciscano AE, Hardee ME, Francis D, Formenti S, Barcellos-Hoff MH. Development of a novel multiplexed assay for quantification of transforming growth factor-ß (TGF-ß). Growth Factors. 2015 Apr; 33(2):79-91. PMID: 25586866.
      View in: PubMed
    20. Du S, Bouquet S, Lo CH, Pellicciotta I, Bolourchi S, Parry R, Barcellos-Hoff MH. Attenuation of the DNA damage response by transforming growth factor-beta inhibitors enhances radiation sensitivity of non-small-cell lung cancer cells in vitro and in vivo. Int J Radiat Oncol Biol Phys. 2015 Jan 1; 91(1):91-9. PMID: 25835621.
      View in: PubMed
    21. Kim MR, Lee J, An YS, Jin YB, Park IC, Chung E, Shin I, Barcellos-Hoff MH, Yi JY. TGFß1 protects cells from ?-IR by enhancing the activity of the NHEJ repair pathway. Mol Cancer Res. 2015 Feb; 13(2):319-29. PMID: 25319009.
      View in: PubMed
    22. Illa-Bochaca I, Ouyang H, Tang J, Sebastiano C, Mao JH, Costes SV, Demaria S, Barcellos-Hoff MH. Densely ionizing radiation acts via the microenvironment to promote aggressive Trp53-null mammary carcinomas. Cancer Res. 2014 Dec 1; 74(23):7137-48. PMID: 25304265.
      View in: PubMed
    23. Nguyen DH, Ouyang H, Mao JH, Hlatky L, Barcellos-Hoff MH. Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice. Cancer Res. 2014 Dec 1; 74(23):7149-58. PMID: 25281718; PMCID: PMC4252877 [Available on 12/01/15].
    24. Barcellos-Hoff MH, Cucinotta FA. New tricks for an old fox: impact of TGFß on the DNA damage response and genomic stability. Sci Signal. 2014 Sep 2; 7(341):re5. PMID: 25185158.
      View in: PubMed
    25. Isacke CM, Barcellos-Hoff MH. Soil amendments that slow cancer growth. Cancer Discov. 2014 Jun; 4(6):637-9. PMID: 24891361.
      View in: PubMed
    26. Arany PR, Cho A, Hunt TD, Sidhu G, Shin K, Hahm E, Huang GX, Weaver J, Chen AC, Padwa BL, Hamblin MR, Barcellos-Hoff MH, Kulkarni AB, J Mooney D. Photoactivation of endogenous latent transforming growth factor-ß1 directs dental stem cell differentiation for regeneration. Sci Transl Med. 2014 May 28; 6(238):238ra69. PMID: 24871130; PMCID: PMC4113395.
    27. Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruis H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes SV, Barcellos-Hoff MH. Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Stem Cells. 2014 Mar; 32(3):649-61. PMID: 24038768.
      View in: PubMed
    28. Bassani L, Graffeo CS, Behrooz N, Tyagi V, Wilson T, Penaranda S, Zagzag D, Rifkin DB, Barcellos-Hoff M, Fatterpekar G, Placantonakis D. Noninvasive diagnosis and management of spontaneous intracranial hypotension in patients with marfan syndrome: Case Report and Review of the Literature. Surg Neurol Int. 2014; 5:8. PMID: 24575323; PMCID: PMC3927088.
    29. Barcellos-Hoff MH, Kleinberg DL. Breast cancer risk in BRCA1 mutation carriers: insight from mouse models. Ann Oncol. 2013 Nov; 24 Suppl 8:viii8-viii12. PMID: 24131977.
      View in: PubMed
    30. Du S, Barcellos-Hoff MH. Tumors as organs: biologically augmenting radiation therapy by inhibiting transforming growth factor ß activity in carcinomas. Semin Radiat Oncol. 2013 Oct; 23(4):242-51. PMID: 24012338; PMCID: PMC3951811.
    31. Barcellos-Hoff MH, Lyden D, Wang TC. The evolution of the cancer niche during multistage carcinogenesis. Nat Rev Cancer. 2013 Jul; 13(7):511-8. PMID: 23760023.
      View in: PubMed
    32. Nguyen DH, Fredlund E, Zhao W, Perou CM, Balmain A, Mao JH, Barcellos-Hoff M. Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes. Clin Cancer Res. 2013 Mar 15; 19(6):1353-62. PMID: 23339125; PMCID: PMC3732211.
    33. Barcellos-Hoff MH. New biological insights on the link between radiation exposure and breast cancer risk. J Mammary Gland Biol Neoplasia. 2013 Mar; 18(1):3-13. PMID: 23325014.
      View in: PubMed
    34. Barcellos-Hoff MH. Does microenvironment contribute to the etiology of estrogen receptor-negative breast cancer? Clin Cancer Res. 2013 Feb 1; 19(3):541-8. PMID: 23325583.
      View in: PubMed
    35. Golden EB, Pellicciotta I, Demaria S, Barcellos-Hoff MH, Formenti SC. The convergence of radiation and immunogenic cell death signaling pathways. Front Oncol. 2012; 2:88. PMID: 22891162; PMCID: PMC3413017.
    36. Hardee ME, Marciscano AE, Medina-Ramirez CM, Zagzag D, Narayana A, Lonning SM, Barcellos-Hoff MH. Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-ß. Cancer Res. 2012 Aug 15; 72(16):4119-29. PMID: 22693253; PMCID: PMC3538149.
    37. Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubinski J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE, Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt Av, Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldés T, Andrés R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigó R, Aiza G, Brunet J, Castellsagué J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Deissler H, Varon-Mateeva R, Sutter C, Niederacher D, Imyamitov E, Sinilnikova OM, Stoppa-Lyonne D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I, Spurdle AB, Beesley J, Chen X, Healey S, Barcellos-Hoff MH, Vidal M, Gruber SB, Lázaro C, Capellá G, McGuffog L, Nathanson KL, Antoniou AC, Chenevix-Trench G, Fleisch MC, Moreno V, Pujana MA. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol. 2011 Nov; 9(11):e1001199. PMID: 22110403; PMCID: PMC3217025.
    38. Bouquet F, Pal A, Pilones KA, Demaria S, Hann B, Akhurst RJ, Babb JS, Lonning SM, DeWyngaert JK, Formenti SC, Barcellos-Hoff M. TGFß1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Clin Cancer Res. 2011 Nov 1; 17(21):6754-65. PMID: 22028490; PMCID: PMC3724539.
    39. Kleinberg DL, Barcellos-Hoff MH. The pivotal role of insulin-like growth factor I in normal mammary development. Endocrinol Metab Clin North Am. 2011 Sep; 40(3):461-71, vii. PMID: 21889714.
      View in: PubMed
    40. Barcellos-Hoff MH. TGFß biology in breast: 15 years on. J Mammary Gland Biol Neoplasia. 2011 Jun; 16(2):65-6. PMID: 21534008.
      View in: PubMed
    41. Nguyen DH, Martinez-Ruiz H, Barcellos-Hoff MH. Consequences of epithelial or stromal TGFß1 depletion in the mammary gland. J Mammary Gland Biol Neoplasia. 2011 Jun; 16(2):147-55. PMID: 21590374.
      View in: PubMed
    42. Nguyen DH, Oketch-Rabah HA, Illa-Bochaca I, Geyer FC, Reis-Filho JS, Mao JH, Ravani SA, Zavadil J, Borowsky AD, Jerry DJ, Dunphy KA, Seo JH, Haslam S, Medina D, Barcellos-Hoff MH. Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. Cancer Cell. 2011 May 17; 19(5):640-51. PMID: 21575864; PMCID: PMC3110779.
    43. Barcellos-Hoff MH, Brenner DJ, Brooks AL, Formenti S, Hlatky L, Locke PA, Shore R, Tenforde T, Travis EL, Williams J. Low-dose radiation knowledge worth the cost. Science. 2011 Apr 15; 332(6027):305-6. PMID: 21493843.
      View in: PubMed
    44. Andarawewa KL, Costes SV, Fernandez-Garcia I, Chou WS, Ravani SA, Park H, Barcellos-Hoff MH. Lack of radiation dose or quality dependence of epithelial-to-mesenchymal transition (EMT) mediated by transforming growth factor ß. Int J Radiat Oncol Biol Phys. 2011 Apr 1; 79(5):1523-31. PMID: 21310544.
      View in: PubMed
    45. Barcellos-Hoff MH. In honor of Mina J. Bissell. Integr Biol (Camb). 2011 Apr; 3(4):253-4. PMID: 21448491.
      View in: PubMed
    46. Barcellos-Hoff MH. What is the use of systems biology approaches in radiation biology? Health Phys. 2011 Mar; 100(3):272-3. PMID: 21595065.
      View in: PubMed
    47. Moses H, Barcellos-Hoff MH. TGF-beta biology in mammary development and breast cancer. Cold Spring Harb Perspect Biol. 2011 Jan; 3(1):a003277. PMID: 20810549; PMCID: PMC3003461.
    48. Barcellos-Hoff MH. Stromal mediation of radiation carcinogenesis. J Mammary Gland Biol Neoplasia. 2010 Dec; 15(4):381-7. PMID: 21181431; PMCID: PMC3068291.
    49. Han J, Chang H, Yang Q, Fontenay G, Groesser T, Barcellos-Hoff MH, Parvin B. Multiscale iterative voting for differential analysis of stress response for 2D and 3D cell culture models. J Microsc. 2011 Mar; 241(3):315-26. PMID: 21118235.
      View in: PubMed
    50. Mukhopadhyay R, Costes SV, Bazarov AV, Hines WC, Barcellos-Hoff MH, Yaswen P. Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Res. 2010; 12(1):R11. PMID: 20146798; PMCID: PMC2880432.
    51. Costes SV, Chiolo I, Pluth JM, Barcellos-Hoff MH, Jakob B. Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutat Res. 2010 Apr-Jun; 704(1-3):78-87. PMID: 20060491; PMCID: PMC3951968.
    52. Shelton DN, Fernandez-Gonzalez R, Illa-Bochaca I, Ortiz-de-Solorzano C, Barcellos-Hoff MH, Welm BE. Use of stem cell markers in dissociated mammary populations. Methods Mol Biol. 2010; 621:49-55. PMID: 20405358.
      View in: PubMed
    53. Illa-Bochaca I, Fernandez-Gonzalez R, Shelton DN, Welm BE, Ortiz-de-Solorzano C, Barcellos-Hoff MH. Limiting-dilution transplantation assays in mammary stem cell studies. Methods Mol Biol. 2010; 621:29-47. PMID: 20405357.
      View in: PubMed
    54. Fernandez-Gonzalez R, Illa-Bochaca I, Shelton DN, Welm BE, Barcellos-Hoff MH, Ortiz-de-Solorzano C. In situ analysis of cell populations: long-term label-retaining cells. Methods Mol Biol. 2010; 621:1-28. PMID: 20405356.
      View in: PubMed
    55. Han J, Chang H, Andarawewa K, Yaswen P, Barcellos-Hoff MH, Parvin B. Multidimensional profiling of cell surface proteins and nuclear markers. IEEE/ACM Trans Comput Biol Bioinform. 2010 Jan-Mar; 7(1):80-90. PMID: 20150670.
      View in: PubMed
    56. Barcellos-Hoff MH, Cordes N. Resistance to radio- and chemotherapy and the tumour microenvironment. Int J Radiat Biol. 2009 Nov; 85(11):920-2. PMID: 19895267.
      View in: PubMed
    57. Barcellos-Hoff MH, Nguyen DH. Radiation carcinogenesis in context: how do irradiated tissues become tumors? Health Phys. 2009 Nov; 97(5):446-57. PMID: 19820454; PMCID: PMC2761885.
    58. Barcellos-Hoff MH, Newcomb EW, Zagzag D, Narayana A. Therapeutic targets in malignant glioblastoma microenvironment. Semin Radiat Oncol. 2009 Jul; 19(3):163-70. PMID: 19464631; PMCID: PMC3538148.
    59. Barcellos-Hoff M, Akhurst RJ. Transforming growth factor-beta in breast cancer: too much, too late. Breast Cancer Res. 2009; 11(1):202. PMID: 19291273; PMCID: PMC2687712.
    60. Beebe D, Barcellos-Hoff MH. The development of integrative biology: bridging the gap--a view from the Scientific Editors. [An interview with David Beebe and Mary Helen Barcellos-Hoff by Kathleen Too]. Integr Biol (Camb). 2009 Feb; 1(2):145-7. PMID: 20023799.
      View in: PubMed
    61. Barcellos-Hoff MH, Beebe D. Integrating biology and technology. Integr Biol (Camb). 2009 Jan; 1(1):14. PMID: 20023786.
      View in: PubMed
    62. Simian M, Bissell MJ, Barcellos-Hoff MH, Shyamala G. Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice. Breast Cancer Res. 2009; 11(5):R72. PMID: 19788752; PMCID: PMC2790852.
    63. Fernandez-Gonzalez R, Illa-Bochaca I, Welm BE, Fleisch MC, Werb Z, Ortiz-de-Solorzano C, Barcellos-Hoff M. Mapping mammary gland architecture using multi-scale in situ analysis. Integr Biol (Camb). 2009 Jan; 1(1):80-9. PMID: 20023794; PMCID: PMC2847439.
    64. Maxwell CA, Fleisch MC, Costes SV, Erickson AC, Boissière A, Gupta R, Ravani SA, Parvin B, Barcellos-Hoff MH. Targeted and nontargeted effects of ionizing radiation that impact genomic instability. Cancer Res. 2008 Oct 15; 68(20):8304-11. PMID: 18922902.
      View in: PubMed
    65. Sudo H, Garbe J, Stampfer MR, Barcellos-Hoff M, Kronenberg A. Karyotypic instability and centrosome aberrations in the progeny of finite life-span human mammary epithelial cells exposed to sparsely or densely ionizing radiation. Radiat Res. 2008 Jul; 170(1):23-32. PMID: 18582160.
      View in: PubMed
    66. Barcellos-Hoff MH. Cancer as an emergent phenomenon in systems radiation biology. Radiat Environ Biophys. 2008 Feb; 47(1):33-8. PMID: 18026977.
      View in: PubMed
    67. Andarawewa KL, Paupert J, Pal A, Barcellos-Hoff MH. New rationales for using TGFbeta inhibitors in radiotherapy. Int J Radiat Biol. 2007 Nov-Dec; 83(11-12):803-11. PMID: 18058368.
      View in: PubMed
    68. Barcellos-Hoff MH, Cordes N. Radiation therapy and the microenvironment. Int J Radiat Biol. 2007 Nov-Dec; 83(11-12):723-5. PMID: 18058363.
      View in: PubMed
    69. Andarawewa KL, Erickson AC, Chou WS, Costes SV, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff M. Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. Cancer Res. 2007 Sep 15; 67(18):8662-70. PMID: 17875706.
      View in: PubMed
    70. Costes SV, Ponomarev A, Chen JL, Nguyen D, Cucinotta FA, Barcellos-Hoff MH. Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Comput Biol. 2007 Aug; 3(8):e155. PMID: 17676951; PMCID: PMC1937017.
    71. Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, Spellman PT, Lorenz K, Lee EH, Barcellos-Hoff M, Petersen OW, Gray JW, Bissell MJ. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol. 2007 Jun; 1(1):84-96. PMID: 18516279.
      View in: PubMed
    72. Parvin B, Yang Q, Han J, Chang H, Rydberg B, Barcellos-Hoff MH. Iterative voting for inference of structural saliency and characterization of subcellular events. IEEE Trans Image Process. 2007 Mar; 16(3):615-23. PMID: 17357723.
      View in: PubMed
    73. Raman S, Maxwell CA, Barcellos-Hoff MH, Parvin B. Geometric approach to segmentation and protein localization in cell culture assays. J Microsc. 2007 Jan; 225(Pt 1):22-30. PMID: 17286692.
      View in: PubMed
    74. Jobling MF, Mott JD, Finnegan MT, Jurukovski V, Erickson AC, Walian PJ, Taylor SE, Ledbetter S, Lawrence CM, Rifkin DB, Barcellos-Hoff MH. Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species. Radiat Res. 2006 Dec; 166(6):839-48. PMID: 17149983.
      View in: PubMed
    75. Fleisch MC, Maxwell CA, Kuper CK, Brown ET, Barcellos-Hoff MH, Costes SV. Intensity-based signal separation algorithm for accurate quantification of clustered centrosomes in tissue sections. Microsc Res Tech. 2006 Dec; 69(12):964-72. PMID: 16941664.
      View in: PubMed
    76. Kirshner J, Jobling MF, Pajares MJ, Ravani SA, Glick AB, Lavin MJ, Koslov S, Shiloh Y, Barcellos-Hoff MH. Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res. 2006 Nov 15; 66(22):10861-9. PMID: 17090522.
      View in: PubMed
    77. Fernández-González R, Muñoz-Barrutia A, Barcellos-Hoff MH, Ortiz-de-Solorzano C. Quantitative in vivo microscopy: the return from the 'omics'. Curr Opin Biotechnol. 2006 Oct; 17(5):501-10. PMID: 16899361.
      View in: PubMed
    78. Fleisch MC, Maxwell CA, Barcellos-Hoff MH. The pleiotropic roles of transforming growth factor beta in homeostasis and carcinogenesis of endocrine organs. Endocr Relat Cancer. 2006 Jun; 13(2):379-400. PMID: 16728569.
      View in: PubMed
    79. Costes SV, Boissière A, Ravani S, Romano R, Parvin B, Barcellos-Hoff MH. Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts. Radiat Res. 2006 May; 165(5):505-15. PMID: 16669704.
      View in: PubMed
    80. Barcellos-Hoff MH, Costes SV. A systems biology approach to multicellular and multi-generational radiation responses. Mutat Res. 2006 May 11; 597(1-2):32-8. PMID: 16417910.
      View in: PubMed
    81. Barcellos-Hoff M, Park C, Wright EG. Radiation and the microenvironment - tumorigenesis and therapy. Nat Rev Cancer. 2005 Nov; 5(11):867-75. PMID: 16327765.
      View in: PubMed
    82. Muraoka-Cook RS, Shin I, Yi JY, Easterly E, Barcellos-Hoff MH, Yingling JM, Zent R, Arteaga CL. Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression. Oncogene. 2006 Jun 8; 25(24):3408-23. PMID: 16186809.
      View in: PubMed
    83. Fernandez-Gonzalez R, Barcellos-Hoff MH, Ortiz-de-Solórzano C. A tool for the quantitative spatial analysis of complex cellular systems. IEEE Trans Image Process. 2005 Sep; 14(9):1300-13. PMID: 16190466.
      View in: PubMed
    84. Grimm SL, Contreras A, Barcellos-Hoff MH, Rosen JM. Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem. 2005 Oct 28; 280(43):36301-9. PMID: 16120603.
      View in: PubMed
    85. Ewan KB, Oketch-Rabah HA, Ravani SA, Shyamala G, Moses HL, Barcellos-Hoff MH. Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice. Am J Pathol. 2005 Aug; 167(2):409-17. PMID: 16049327; PMCID: PMC1603552.
    86. Barcellos-Hoff MH. Integrative radiation carcinogenesis: interactions between cell and tissue responses to DNA damage. Semin Cancer Biol. 2005 Apr; 15(2):138-48. PMID: 15652459.
      View in: PubMed
    87. Muraoka-Cook RS, Kurokawa H, Koh Y, Forbes JT, Roebuck LR, Barcellos-Hoff MH, Moody SE, Chodosh LA, Arteaga CL. Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Res. 2004 Dec 15; 64(24):9002-11. PMID: 15604265.
      View in: PubMed
    88. Stone HB, Moulder JE, Coleman CN, Ang KK, Anscher MS, Barcellos-Hoff M, Dynan WS, Fike JR, Grdina DJ, Greenberger JS, Hauer-Jensen M, Hill RP, Kolesnick RN, Macvittie TJ, Marks C, McBride WH, Metting N, Pellmar T, Purucker M, Robbins ME, Schiestl RH, Seed TM, Tomaszewski JE, Travis EL, Wallner PE, Wolpert M, Zaharevitz D. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res. 2004 Dec; 162(6):711-28. PMID: 15548121.
      View in: PubMed
    89. Barcellos-Hoff MH, Medina D. New highlights on stroma-epithelial interactions in breast cancer. Breast Cancer Res. 2005; 7(1):33-6. PMID: 15642180; PMCID: PMC1064117.
    90. Fernandez-Gonzalez R, Barcellos-Hoff MH, Ortiz-de-Solórzano C. Quantitative image analysis in mammary gland biology. J Mammary Gland Biol Neoplasia. 2004 Oct; 9(4):343-59. PMID: 15838604.
      View in: PubMed
    91. Coleman CN, Stone HB, Alexander GA, Barcellos-Hoff MH, Bedford JS, Bristow RG, Dynlacht JR, Fuks Z, Gorelic LS, Hill RP, Joiner MC, Liu FF, McBride WH, McKenna WG, Powell SN, Robbins ME, Rockwell S, Schiff PB, Shaw EG, Siemann DW, Travis EL, Wallner PE, Wong RS, Zeman EM. Education and training for radiation scientists: radiation research program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003. Radiat Res. 2003 Dec; 160(6):729-37. PMID: 14640790.
      View in: PubMed
    92. Park CC, Henshall-Powell RL, Erickson AC, Talhouk R, Parvin B, Bissell MJ, Barcellos-Hoff MH. Ionizing radiation induces heritable disruption of epithelial cell interactions. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10728-33. PMID: 12960393; PMCID: PMC196872.
    93. Erickson AC, Barcellos-Hoff MH. The not-so innocent bystander: the microenvironment as a therapeutic target in cancer. Expert Opin Ther Targets. 2003 Feb; 7(1):71-88. PMID: 12556204.
      View in: PubMed
    94. Parvin B, Yang Q, Fontenay G, Barcellos-Hoff MH. BioSig: an imaging bioinformatics system for phenotypic analysis. IEEE Trans Syst Man Cybern B Cybern. 2003; 33(5):814-24. PMID: 18238234.
      View in: PubMed
    95. Fernandez-Gonzalez R, Jones A, Garcia-Rodriguez E, Chen PY, Idica A, Lockett SJ, Barcellos-Hoff MH, Ortiz-De-Solorzano C. System for combined three-dimensional morphological and molecular analysis of thick tissue specimens. Microsc Res Tech. 2002 Dec 15; 59(6):522-30. PMID: 12467029.
      View in: PubMed
    96. Ewan KB, Henshall-Powell RL, Ravani SA, Pajares MJ, Arteaga C, Warters R, Akhurst RJ, Barcellos-Hoff M. Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res. 2002 Oct 15; 62(20):5627-31. PMID: 12384514.
      View in: PubMed
    97. Ortiz De Solórzano C, Costes S, Callahan DE, Parvin B, Barcellos-Hoff MH. Applications of quantitative digital image analysis to breast cancer research. Microsc Res Tech. 2002 Oct 15; 59(2):119-27. PMID: 12373722.
      View in: PubMed
    98. Wang F, Hansen RK, Radisky D, Yoneda T, Barcellos-Hoff MH, Petersen OW, Turley EA, Bissell MJ. Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst. 2002 Oct 2; 94(19):1494-503. PMID: 12359858; PMCID: PMC2975573.
    99. Ewan KB, Shyamala G, Ravani SA, Tang Y, Akhurst R, Wakefield L, Barcellos-Hoff M. Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am J Pathol. 2002 Jun; 160(6):2081-93. PMID: 12057913; PMCID: PMC1850834.
    100. Costes S, Barcellos-Hoff MH. Radiation quality and tissue-specific microenvironments following exposure to 1 GeV/amu Fe. Adv Space Res. 2002; 30(4):865-70. PMID: 12530433.
      View in: PubMed
    101. Girault I, Karu AE, Schaper M, Barcellos-Hoff MH, Hagen T, Vogel DS, Ames BN, Christen S, Shigenaga MK. Immunodetection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC. Free Radic Biol Med. 2001 Dec 1; 31(11):1375-87. PMID: 11728809.
      View in: PubMed
    102. Barcellos-Hoff MH, Brooks AL. Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability. Radiat Res. 2001 Nov; 156(5 Pt 2):618-27. PMID: 11604083.
      View in: PubMed
    103. Barcellos-Hoff MH. It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment. J Mammary Gland Biol Neoplasia. 2001 Apr; 6(2):213-21. PMID: 11501581.
      View in: PubMed
    104. Asch BB, Barcellos-Hoff MH. Epigenetics and breast cancer. J Mammary Gland Biol Neoplasia. 2001 Apr; 6(2):151-2. PMID: 11501575.
      View in: PubMed
    105. Barcellos-Hoff MH. Three down and counting: the transformation of human mammary cells from normal to malignant in three steps. Trends Mol Med. 2001 Apr; 7(4):142-3. PMID: 11286925.
      View in: PubMed
    106. Kong FM, Anscher MS, Sporn TA, Washington MK, Clough R, Barcellos-Hoff MH, Jirtle RL. Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury. Int J Radiat Oncol Biol Phys. 2001 Jan 1; 49(1):35-41. PMID: 11163495.
      View in: PubMed
    107. Chang PY, Bjornstad K A, Chang E, McNamara M, Barcellos-Hoff MH, Lin SP, Aragon G, Polansky JR, Lui GM, Blakely EA. Particle irradiation induces FGF2 expression in normal human lens cells. Radiat Res. 2000 Nov; 154(5):477-84. PMID: 11025644.
      View in: PubMed
    108. Costes S, Streuli CH, Barcellos-Hoff MH. Quantitative image analysis of laminin immunoreactivity in skin basement membrane irradiated with 1 GeV/nucleon iron particles. Radiat Res. 2000 Oct; 154(4):389-97. PMID: 11023602.
      View in: PubMed
    109. Park CC, Bissell MJ, Barcellos-Hoff MH. The influence of the microenvironment on the malignant phenotype. Mol Med Today. 2000 Aug; 6(8):324-9. PMID: 10904250.
      View in: PubMed
    110. Barcellos-Hoff MH, Ravani SA. Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 2000 Mar 1; 60(5):1254-60. PMID: 10728684.
      View in: PubMed
    111. Barcellos-Hoff MH, Ewan KB. Transforming growth factor-beta and breast cancer: Mammary gland development. Breast Cancer Res. 2000; 2(2):92-9. PMID: 11250698; PMCID: PMC139430.
    112. O'Malley Y, Zhao W, Barcellos-Hoff MH, Robbins ME. Radiation-induced alterations in rat mesangial cell Tgfb1 and Tgfb3 gene expression are not associated with altered secretion of active Tgfb isoforms. Radiat Res. 1999 Dec; 152(6):622-8. PMID: 10581532.
      View in: PubMed
    113. Vodovotz Y, Mitchell JB, Lucia MS, McKinney L, Kollum M, Cottin Y, Chan RC, Barcellos-Hoff MH, Waksman R. Modulation of protein expression and activity by radiation: relevance to intracoronary radiation for the prevention of restenosis. Cardiovasc Radiat Med. 1999 Oct-Dec; 1(4):336-43. PMID: 10828563.
      View in: PubMed
    114. Tribble DL, Barcellos-Hoff MH, Chu BM, Gong EL. Ionizing radiation accelerates aortic lesion formation in fat-fed mice via SOD-inhibitable processes. Arterioscler Thromb Vasc Biol. 1999 Jun; 19(6):1387-92. PMID: 10364068.
      View in: PubMed
    115. Vodovotz Y, Chesler L, Chong H, Kim SJ, Simpson JT, DeGraff W, Cox GW, Roberts AB, Wink DA, Barcellos-Hoff M. Regulation of transforming growth factor beta1 by nitric oxide. Cancer Res. 1999 May 1; 59(9):2142-9. PMID: 10232601.
      View in: PubMed
    116. Chong H, Vodovotz Y, Cox GW, Barcellos-Hoff MH. Immunocytochemical localization of latent transforming growth factor-beta1 activation by stimulated macrophages. J Cell Physiol. 1999 Mar; 178(3):275-83. PMID: 9989773.
      View in: PubMed
    117. Barcellos-Hoff MH. How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues. Radiat Res. 1998 Nov; 150(5 Suppl):S109-20. PMID: 9806614.
      View in: PubMed
    118. Barcellos-Hoff MH. The potential influence of radiation-induced microenvironments in neoplastic progression. J Mammary Gland Biol Neoplasia. 1998 Apr; 3(2):165-75. PMID: 10819525.
      View in: PubMed
    119. Shyamala G, Yang X, Silberstein G, Barcellos-Hoff MH, Dale E. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. Proc Natl Acad Sci U S A. 1998 Jan 20; 95(2):696-701. PMID: 9435255; PMCID: PMC18483.
    120. Shyamala G, Barcellos-Hoff MH, Toft D, Yang X. In situ localization of progesterone receptors in normal mouse mammary glands: absence of receptors in the connective and adipose stroma and a heterogeneous distribution in the epithelium. J Steroid Biochem Mol Biol. 1997 Nov-Dec; 63(4-6):251-9. PMID: 9459191.
      View in: PubMed
    121. Ehrhart EJ, Segarini P, Tsang ML, Carroll AG, Barcellos-Hoff MH. Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation. FASEB J. 1997 Oct; 11(12):991-1002. PMID: 9337152.
      View in: PubMed
    122. Reiss M, Barcellos-Hoff MH. Transforming growth factor-beta in breast cancer: a working hypothesis. Breast Cancer Res Treat. 1997 Aug; 45(1):81-95. PMID: 9285120.
      View in: PubMed
    123. Franko AJ, Sharplin J, Ghahary A, Barcellos-Hoff MH. Immunohistochemical localization of transforming growth factor beta and tumor necrosis factor alpha in the lungs of fibrosis-prone and "non-fibrosing" mice during the latent period and early phase after irradiation. Radiat Res. 1997 Feb; 147(2):245-56. PMID: 9008217.
      View in: PubMed
    124. Barcellos-Hoff MH. Latency and activation in the control of TGF-beta. J Mammary Gland Biol Neoplasia. 1996 Oct; 1(4):353-63. PMID: 10887509.
      View in: PubMed
    125. Barcellos-Hoff MH, Dix TA. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol. 1996 Sep; 10(9):1077-83. PMID: 8885242.
      View in: PubMed
    126. Ehrhart EJ, Gillette EL, Barcellos-Hoff MH. Immunohistochemical evidence of rapid extracellular matrix remodeling after iron-particle irradiation of mouse mammary gland. Radiat Res. 1996 Feb; 145(2):157-62. PMID: 8606925.
      View in: PubMed
    127. Barcellos-Hoff MH. Latency and activation in the control of TGF-beta. J Mammary Gland Biol Neoplasia. 1996; 1(4):353-63. PMID: 11543607.
      View in: PubMed
    128. Barcellos-Hoff MH, Ehrhart EJ, Kalia M, Jirtle R, Flanders K, Tsang ML. Immunohistochemical detection of active transforming growth factor-beta in situ using engineered tissue. Am J Pathol. 1995 Nov; 147(5):1228-37. PMID: 7485387; PMCID: PMC1869520.
    129. Barcellos-Hoff M, Derynck R, Tsang ML, Weatherbee JA. Transforming growth factor-beta activation in irradiated murine mammary gland. J Clin Invest. 1994 Feb; 93(2):892-9. PMID: 8113421; PMCID: PMC293960.
    130. Barcellos-Hoff MH. Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Res. 1993 Sep 1; 53(17):3880-6. PMID: 8358713.
      View in: PubMed
    131. Barcellos-Hoff M, Linfoot PA, Marton LJ, Deen DF. Production of stable phenotypes from 9L rat brain tumor multicellular spheroids treated with 1,3-bis(2-chloroethyl)-1-nitrosourea. Int J Cancer. 1992 Sep 30; 52(3):409-13. PMID: 1399117.
      View in: PubMed
    132. Barcellos-Hoff MH. Mammary epithelial reorganization on extracellular matrix is mediated by cell surface galactosyltransferase. Exp Cell Res. 1992 Jul; 201(1):225-34. PMID: 1612125.
      View in: PubMed
    133. Aggeler J, Ward J, Blackie LM, Barcellos-Hoff MH, Streuli CH, Bissell MJ. Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo. J Cell Sci. 1991 Jun; 99 ( Pt 2):407-17. PMID: 1885677.
      View in: PubMed
    134. Barcellos-Hoff M, Marton LJ, Deen DF. Differential drug sensitivity conferred by growth status detected in a mixed population of cycling and noncycling cells. Cancer Res. 1990 Jun 15; 50(12):3551-5. PMID: 2340503.
      View in: PubMed
    135. Barcellos-Hoff MH, Aggeler J, Ram TG, Bissell MJ. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development. 1989 Feb; 105(2):223-35. PMID: 2806122; PMCID: PMC2948482.
    136. Deen DF, Morgan WF, Tofilon PJ, Barcellos-Hoff M. Measurement of sister chromatid exchanges and their relationship to DNA damage, repair and cell killing. Pharmacol Ther. 1989; 42(3):349-60. PMID: 2672050.
      View in: PubMed
    137. Linfoot PA, Barcellos-Hoff M, Brent TP, Marton LJ, Deen DF. Cell-cycle, phase-specific cell killing by carmustine in sensitive and resistant cells. NCI Monogr. 1988; (6):183-6. PMID: 3352762.
      View in: PubMed
    138. Lee EY, Barcellos-Hoff MH, Chen LH, Parry G, Bissell MJ. Transferrin is a major mouse milk protein and is synthesized by mammary epithelial cells. In Vitro Cell Dev Biol. 1987 Mar; 23(3):221-6. PMID: 3549678.
      View in: PubMed
    139. Bissell MJ, Barcellos-Hoff MH. The influence of extracellular matrix on gene expression: is structure the message? J Cell Sci Suppl. 1987; 8:327-43. PMID: 3332665.
      View in: PubMed
    140. Jostes RF, Williams ME, Barcellos-Hoff MH, Hoshino T, Deen DF. Growth delay in 9L rat brain tumor spheroids after irradiation with single and split doses of X rays. Radiat Res. 1985 May; 102(2):182-9. PMID: 4070541.
      View in: PubMed
    141. da Silva V, Gutin PH, Barcellos-Hoff MH, Bernstein MA, Deen DF, Weaver KA. The effect of combination treatment with cis-platinum and low dose rate 125I radiation in a murine brachytherapy model. Int J Radiat Oncol Biol Phys. 1984 Aug; 10(8):1471-2. PMID: 6540767.
      View in: PubMed
    Mary Helen's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP