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    Matilda Chan, MD, PhD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    Address1001 Potrero Ave
    San Francisco CA 94110
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      Collapse Biography 
      Collapse Education and Training
      University of California, San FranciscoClinical Fellowship School of Medicine
      Keck/University of Southern CaliforniaM.D., Ph.D.School of Medicine2002

      Collapse Overview 
      Collapse Overview
      Matilda Chan is a cornea specialist at the F.I. Proctor Foundation. Her clinical expertise is the diagnosis and management of patients with corneal and ocular surface diseases. Her basic and translational research program focuses on understanding the cellular and molecular responses to corneal injury.

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Altiok EI, Browne S, Khuc E, Moran EP, Qiu F, Zhou K, Santiago-Ortiz JL, Ma JX, Chan MF, Healy KE. sFlt Multivalent Conjugates Inhibit Angiogenesis and Improve Half-Life In Vivo. PLoS One. 2016; 11(6):e0155990. PMID: 27257918.
        View in: PubMed
      2. Chou J, Chan MF, Werb Z. Metalloproteinases: a Functional Pathway for Myeloid Cells. Microbiol Spectr. 2016 Apr; 4(2). PMID: 27227311.
        View in: PubMed
      3. Maltseva I, Chan M, Kalus I, Dierks T, Rosen SD. The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair. PLoS One. 2013; 8(8):e69642. PMID: 23950901; PMCID: PMC3738537.
      4. Chan MF, Li J, Bertrand A, Casbon AJ, Lin JH, Maltseva I, Werb Z. Protective effects of matrix metalloproteinase-12 following corneal injury. J Cell Sci. 2013 Sep 1; 126(Pt 17):3948-60. PMID: 23813962; PMCID: PMC3757333.
      5. Dalmon C, Porco TC, Lietman TM, Prajna NV, Prajna L, Das MR, Kumar JA, Mascarenhas J, Margolis TP, Whitcher JP, Jeng BH, Keenan JD, Chan MF, McLeod SD, Acharya NR. The clinical differentiation of bacterial and fungal keratitis: a photographic survey. Invest Ophthalmol Vis Sci. 2012 Apr; 53(4):1787-91. PMID: 22395880; PMCID: PMC3342793.
      6. Chan MF, Sack R, Quigley DA, Sathe S, Vijmasi T, Li S, Holsclaw D, Strauss EC, McNamara NA. Membrane array analysis of tear proteins in ocular cicatricial pemphigoid. Optom Vis Sci. 2011 Aug; 88(8):1005-9. PMID: 21552176; PMCID: PMC3667701.
      7. Oldenburg CE, Keenan JD, Cevallos V, Chan MF, Acharya NR, Gaynor BD, McLeod SD, Esterberg EJ, Porco TC, Lietman TM. Microbiological cure times in acanthamoeba keratitis. Eye (Lond). 2011 Sep; 25(9):1155-60. PMID: 21637300; PMCID: PMC3178241.
      8. Hu AY, Strauss EC, Holland GN, Chan MF, Yu F, Margolis TP. Late varicella-zoster virus dendriform keratitis in patients with histories of herpes zoster ophthalmicus. Am J Ophthalmol. 2010 Feb; 149(2):214-220.e3. PMID: 19909942; PMCID: PMC4507370.
      9. Rutar T, Chan MF, Acharya NR, Naseri A. Cicatrising conjunctivitis due to paraneoplastic pemphigoid. Br J Ophthalmol. 2007 Nov; 91(11):1562-3. PMID: 17947274; PMCID: PMC2095435.
      10. Sappington RM, Chan M, Calkins DJ. Interleukin-6 protects retinal ganglion cells from pressure-induced death. Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):2932-42. PMID: 16799036.
        View in: PubMed
      11. Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, Laird PW, Jones PA. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol. 2002 Jan; 22(2):480-91. PMID: 11756544; PMCID: PMC139739.
      12. Chan MF, van Amerongen R, Nijjar T, Cuppen E, Jones PA, Laird PW. Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells. Mol Cell Biol. 2001 Nov; 21(22):7587-600. PMID: 11604495; PMCID: PMC99930.
      13. Chan MF, Liang G, Jones PA. Relationship between transcription and DNA methylation. Curr Top Microbiol Immunol. 2000; 249:75-86. PMID: 10802939.
        View in: PubMed
      14. Simoneau AR, Spruck CH, Gonzalez-Zulueta M, Gonzalgo ML, Chan MF, Tsai YC, Dean M, Steven K, Horn T, Jones PA. Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations. Cancer Res. 1996 Nov 1; 56(21):5039-43. PMID: 8895761.
        View in: PubMed
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